Transformation of natural genetic variation into haemophilus influenzae genomes

UBC microbiologist Rosie Redfield was named one of “Ten People Who Mattered This Year” in the Nature journal as reported by UBC’s Public Affairs in December 2011. And, now you can view her peer-reviewed, full-text journal article that was recently added to the Canadian Institutes of Health Research (CIHR) Research Outputs at UBC collection in cIRcle at: Below is a quick snapshot about her article:

Author Summary

The ability of bacteria to acquire genetic information from their relatives—called natural competence—poses a major health risk, since recombination between pathogenic bacterial lineages can help bacteria develop resistance to antibiotics and adapt to host defenses. In this study we transformed competent cells of the human pathogen Haemophilus influenzae with genomic DNA from a divergent clinical isolate and used deep sequencing to identify the recombination events in four transformed chromosomes. The results show that transformation of single competent cells is more extensive than expected, and suggests that transformation can be used as a tool to map traits that vary between clinical isolates.

 Did you know?

The Canadian Institutes of Health Research (CIHR) Research Outputs at UBC community in cIRcle supports UBC researchers in complying with the CIHR’s Policy on Access to Research Outputs. This CIHR cIRcle community is found at:

Above Redfield Lab image credit:

Above Public Affairs’ news item is available at:



The Vancouver School Board is has an article on the public opinion’s effect on the future of public education in Vancouver.  Find out more here.

Vancouver School Board Sectoral Review: Our Schools, Our Programs, Our Future pdf here.

A reminder that Rare Books and Special Collections, University Archives and the Chung Collection will be closed on Good Friday (April 6) and Easter Monday (April 9). We are however open on Saturday April 7 from 12-5 as usual. For full details on RBSC hours, click here.

Kitamaat Mission Easter Sunday broadside

Kitamaat Mission Easter Sunday broadside

The broadside above is from a collection of 55 broadsides from the Kitamaat Mission from 1894-1902, recently added to the Chung Collection. These sheets were used for teaching purposes at Sunday morning services at the mission, and are printed in both the English and Haisla languages. Material published from mission presses are important resources for understanding the interactions between Christian missionaries and First Nations people, and also are used as a source for historical transliterations of First Nations languages.  For more resources similar to this one, try searching the library catalogue for “mission press,” or for the name of a specific mission.

a place of mind, The University of British Columbia

UBC Library





Emergency Procedures | Accessibility | Contact UBC | © Copyright The University of British Columbia

Spam prevention powered by Akismet