Video sponsored by the Irving K. Barber Learning Centre. Schools participate in the Aboriginal Enhancement Schools Network (AESN) on a voluntary and annual basis. AESN schools link their inquiry specifically to Aboriginal ways of knowing. The Spiral of Inquiry provides school teams with the structure for guiding their improvement and innovation work. Participating schools develop and submit an inquiry focus, collaborate with colleagues through regional meetings, and share case studies in a spirit of generosity and curiosity.

Speakers:

Lynne Tomlinson (Director of Instruction), SD 45, West Vancouver

Trish Catherine (Teacher), Ecole Ballenas Secondary SD 69, Qualicum

Paul Boyd (Teacher) WL Seaton Secondary, SD 22, Vernon

Marcus Toneatto (Principal), South Okanagan Secondary School, SD 53, Okanagan Similkameen

Mary Neto (Teacher), Smithers Secondary, SD 54, Bulkley Valley

Roberta Edzerza, (District Principal, Aboriginal Education) and Sandy Pond (Principal), Charles Hays Secondary, SD 53, Prince Rupert

Robert Taddei, (Teacher), Frank Hurt Secondary SD 36, Surrey

 

 

 

 

 

 

As part of the 44th Annual Conference of the Canadian Association of Information Science (CAIS), Jennifer Preece, Professor of the College of Information Studies at University of Maryland will be hosting a discussion about the new challenges for Information Studies in this period, known as the anthropocene. Humans are now having a profound influence on the planet, changing the atmosphere we breathe and reshaping the earth’s surface, thereby triggering species extinction at an alarming rate.

Information Studies professionals and students can have a profound influence on the data that is collected, how it is stored, retrieved and communicated with citizens and communities. We have a responsibility to help to heal our planet by raising awareness and triggering action. This talk challenges researchers, practitioners, teachers and students to lead the way in shaping a sustainable future. We can change information processes and technology, raise awareness, and engage citizens to contribute to science and their own communities by becoming “citizen scientists”.

This event happened on November 9, 2016.


Speaker:

Jennifer Preece, co-author of Interaction Design: Beyond Human Computer Interaction (4th Edition, 2015), helped to define research on online communities through her book Online Communities: Designing Usability, Supporting Sociability, 2000. Her current research focuses on information processes and technology for supporting citizen and environmental science; with an emphasis on community participation for collecting biodiversity data. Preece was dean of the College of Information Studies – Maryland’s iSchool for ten years from 2005 – 2015. Click here for further information about her career.

 


Select Books and Articles Available at UBC Library

Andrews, D., Nonnecke, B., & Preece, J. (2003). Electronic survey methodology: A case study in reaching hard-to-involve internet users. International Journal of Human-Computer Interaction, 16(2), 185-210. doi:10.1207/S15327590IJHC1602_04 [Link]

Preece, J. (2016). Citizen science: New research challenges for human-computer interaction. International Journal of Human-Computer Interaction, 32(8), 585-612. doi:10.1080/10447318.2016.1194153 [Link]

Sharp, H., Rogers, Y., & Preece, J. (2007). Interaction design: Beyond human-computer interaction (2nd ed.). Chichester;Hoboken, NJ;: Wiley. [Available at Koerner Library Stacks QA76.9.H85 P72 2007]

 


UBC Library Research Guides

Library Archival and Information Science

In collaboration with the Public Scholars Initiative (PSI), the IKBLC Community Engagement & Programs division presents the “PhDs Go Public Research Talk Series,” which showcases doctoral students telling their community-engaged research stories in just under seven minutes.

In “Human(e) Interactions with the Environment,” nine PhD students from UBC’s Public Scholars Initiative engage the public by using the Pecha Kucha format to present on how their research is contributing to the public good, and making a change in the world.  This year’s PSI themes include education, environment, culture, social justice, and health.

This event happened on Wednesday, 15 March 2017.


Speakers

Yemi Adeyeye (Forestry)

Evan Bowness (IRES)

Mollie Chapman (IRES)

Tugce Conger (IRES)

Jamie Fenneman (Botany)

Graham McDowell (IRES)

Emily Rugel (Population and Public Health)

Steve Williams (IRES)

Stefan Pauer (Law).


Select Books and Articles Available at UBC Library

Chapman, M. (2005). Once upon a time in volcán, costa rica: Integrating values into watershed management and poverty alleviation. Review of Policy Research, 22(6), 859-880. doi:10.1111/j.1541-1338.2005.00179.x [Link]

Comack, E., & Bowness, E. (2010). Dealing the race card: Public discourse on the policing of winnipeg’s inner-city communities. Canadian Journal of Urban Research, 19(1), 34-50. [Link]

Toft, M., Adeyeye, Y., & Lund, J. (2015). The use and usefulness of inventory-based management planning to forest management: Evidence from community forestry in nepal. Forest Policy and Economics, 60, 35-49. doi:10.1016/j.forpol.2015.06.007 [Link]

Williams, S., Bradley, H., Devadson, R., & Erickson, M. (2013). Globalization and work. Cambridge: Polity Press. [Available at Koerner Library Stacks HD6955 .W55 2013]


UBC Library Research Guides

Education

Worlds at Home: On Cosmopolitan Futures is a public symposium bringing together scholars from across Canada, the US and Australia to consider the future of cosmopolitanism as a critical approach to scholarship and praxis. The program will feature an interview with Dr. Sneja Gunew (UBC) and a launch of her book, Post-multicultural Writers as Neo-cosmopolitan Mediators (Anthem Press), a keynote address by Dr. Pheng Cheah (UC Berkeley) and more.

Speakers: Shani Mootoo, Lydia Kwa, Larissa Lai (University of Calgary) 


Select Books and Articles Available at UBC Library

Bradley, A., & Bradley, A. (10/01/2010). International journal of refugee law: Beyond borders; cosmopolitanism and family reunification for refugees in canada Oxford University Press. doi:10.1093/ijrl/eeq025 [Link]

Breckenridge, C. A. (2002). Cosmopolitanism Duke University Press. [Link]

Gunew, S. M., & Rizvi, F. (1994). Culture, difference and the arts. St Leonards, NSW, Australia: Allen & Unwin. [Available at Koerner Library Stacks DU120 .C85 1994]


UBC Library Research Guides

Anthropology

Education

 

In collaboration with the Public Scholars Initiative (PSI), the IKBLC Community Engagement & Programs division presents the “PhDs Go Public Research Talk Series,” which showcases doctoral students telling their community-engaged research stories in just under seven minutes.

In “Explorations in Culture and Diversity,” eight PhD students from UBC’s Public Scholars Initiative engage the public by using the Pecha Kucha format to present on how their research is contributing to the public good, and making a change in the world.  This year’s PSI themes include education, environment, culture, social justice, and health.

This event happened on Thursday, March 23, 2017.


Speakers

Ashli Akins (Interdisciplinary Studies)

Eury Chang (Theatre)

Severn Cullis-Suzuki (Anthroplogy)

Claire Fogal (Theatre)

Gregory Gan (Anthropology)

Lily Ivanova (Sociology)

Stephanie Nakagawa (Opera)

Teilhard Paradela (History)


Select Books and Articles Available at UBC Library

Chang, E. C. (01/01/2015). Theatre research in canada: Towards reconciliation: Immigration in marty chan’s the forbidden phoenix and david yee’s lady in the red dress Graduate Centre for Study of Drama. [Link]

Cullis-Suzuki, S. (2007). Notes from canada’s young activists : A generation stands up for change Greystone Books. [Link]

Gan, G. (2015). Soaring to dizzying heights: Christ the saviour cathedral as a historical arena for the persecution of pussy riot. Critique of Anthropology, 35(2), 166-186. doi:10.1177/0308275X15569852 [Link]

Ivanova, L. (2014). The cultural transmission of morals : A case study of western visitors to cambodia’s genocide museums [Link]


UBC Library Research Guides

Anthropology

Education

Sociology

Theatre

Research Day showcases the contributions of the iSchool students and faculty working at the intersections of archival, information, library and children’s literature studies.

Questions about social media as sources of information about individuals (of different ages, genders, backgrounds) and communities, their uses in our personal and professional lives, and impact on our practices and overall well-being are central to the work of students and scholars across all our iSchool programs. Recognizing this common ground, this year’s Research Day will focus on the broad topic of “information, social media, and well-being,” considering the many connections social media now have with the way we do information, library, and archival studies.

This event happened on March 10, 2017.


Speaker:

Lyle Ungar, Professor of Computer And Information Science, University of Pennsylvania

Dr. Lyle Ungar is a Professor of Computer and Information Science at the University of Pennsylvania, where he also holds appointments in multiple departments in the Schools of Business, Medicine, Arts and Sciences, and Engineering and Applied Science.  Lyle received a B.S. from Stanford University and a Ph.D. from M.I.T.  He has published over 200 articles, supervised two dozen PhD students, and is co-inventor on eleven patents. His current research focuses on developing scalable machine learning methods for data mining and text mining, including spectral methods for NLP, and analysis of social media to better understand the drivers of physical and mental well-being.

“Social media such as Twitter and Facebook provide a rich, if imperfect portal onto people’s lives.  We analyze tens of millions of Facebook posts and billions of tweets to study variation in language use with age, gender, personality, and mental and physical well-being.  Word clouds visually illustrate the big five personality traits (e.g., “What is it like to be neurotic?”), while correlations between language use and county level health data suggest connections between health and happiness, including potential psychological causes of heart disease.”


Select Books and Articles Available at UBC Library

Smith, R. J., Crutchley, P., Schwartz, H. A., Ungar, L., Shofer, F., Padrez, K. A., & Merchant, R. M. (2017). Variations in Facebook Posting Patterns Across Validated Patient Health Conditions: A Prospective Cohort Study. Journal of Medical Internet Research, 19(1), e7. [Link]

Carpenter, J., Preotiuc-Pietro, D., Flekova, L., Giorgi, S., Hagan, C., Kern, M. L., … & Seligman, M. E. (2016). Real Men Don’t Say “Cute” Using Automatic Language Analysis to Isolate Inaccurate Aspects of Stereotypes. Social Psychological and Personality Science, 1948550616671998. [Link]

Kern, M. L., Park, G., Eichstaedt, J. C., Schwartz, H. A., Sap, M., Smith, L. K., & Ungar, L. H. (2016). Gaining insights from social media language: Methodologies and challenges. [Link]

Sinnenberg, L., DiSilvestro, C. L., Mancheno, C., Dailey, K., Tufts, C., Buttenheim, A. M., … & Asch, D. A. (2016). Twitter as a Potential Data Source for Cardiovascular Disease Research. Jama cardiology, 1(9), 1032-1036. [Link]

Carpenter, J., Preotiuc-Pietro, D., Flekova, L., Giorgi, S., Hagan, C., Kern, M. L., … & Seligman, M. E. (2016). Real Men Don’t Say “Cute” Using Automatic Language Analysis to Isolate Inaccurate Aspects of Stereotypes. Social Psychological and Personality Science, 1948550616671998. [Link]

Brooks, S. (05/01/2015). Computers in human behavior: Does personal social media usage affect efficiency and well-being? Elsevier. doi:10.1016/j.chb.2014.12.053 [Link]

Gerson, J., Plagnol, A. C., & Corr, P. J. (10/01/2016). Computers in human behavior: Subjective well-being and social media use: Do personality traits moderate the impact of social comparison on facebook? Elsevier. doi:10.1016/j.chb.2016.06.023 [Link]


UBC Library Research Guides

Computer Science

Information Visualization

 

This session aims to identify ways to support and promote accurate information about Aboriginal people, identify how current library structures may be barriers to full inclusion for Aboriginal students and how to address them, and identify power issues at play in our own instructional practice and how to make positive changes. Panelists are asked to consider the following questions:

How do you help your community find themselves in your collection or in your course?
How do you Indigenize your instruction?


Panelists

Deborah Lee is a Cree, Mohawk and Métis librarian. She worked as a Reference Librarian at the National Library of Canada / Library and Archives Canada for seven years. In 2007, Deborah became the Indigenous Studies Portal Librarian at the University of Saskatchewan. She has been the Indigenous Studies Liaison and Aboriginal Engagement Librarian at UofS since 2011. Deborah has presented widely at local, national and international conferences, including ACRL in 2015.

Patricia Geddes is the Student Engagement and Community Outreach Librarian at Vancouver Island University. She is a Liaison Librarian for Aboriginal Education Services, First Nations Studies, and the Faculty of Academic and Career Preparation.

Jenna Walsh was born in Vancouver on unceded Coast Salish territory and grew up in an inner city neighbourhood with a diverse Aboriginal population. At the University of British Columbia, her Interdisciplinary BA focused on global Indigeneity, and she did the First Nations Curriculum Concentration program for her MLIS.

Kim Lawson is Heiltsuk with English/ Danish ancestry. She is one of the authors of the “Protocols for Native American Archival Materials,” was the Archivist/ Librarian at The Union of BC Indian Chiefs Resource Centre, has an MLIS from UBC and is learning to speak Heiltsuk.

Camille Callison is a member of the Tahltan First Nation and the Indigenous Services Librarian & Liaison Librarian for Anthropology, Native Studies and Social Work at the University of Manitoba, Member of the UM Indigenous Advisory Circle (IAC) and has presented extensively on Indigenous Library & Archives issues.

Moderator

Sarah Dupont’s ancestry is Metis, French, and British. She is from Prince George, BC and is the Aboriginal Engagement Librarian at UBC Library, where she works in the Xwi7xwa Library and Irving K Barber Learning Centre. Her liaison areas include Indigenous Education and Indigenous Social Work. Sarah is the project manager for Indigitization, a UBC program to support First Nations digitization and preservation of their community resources.


Select Books and Articles Available at UBC Library

Doerksen, K., Karen Doerksen, & Carla Martin. (03/01/2016). Partnership: A loose coupling: Aboriginal participation in library education – A selective literature review The Partnership, provincial and territorial library association of Canada c/o Ontario Library Associ. doi:10.21083/partnership.v10i2.3337 [Link]

Face, M., & Hollens, D. (2004). A Digital Library to Serve a Region: The Bioregion and First Nations Collections of the Southern Oregon Digital Archives. Reference & User Services Quarterly, 44(2), 116-121. [Link]

Kelly, B., & Barbara Kelly. (01/01/2011). Partnership: Reflecting the lives of aboriginal women in canadian public library collection development The Partnership, provincial and territorial library association of Canada c/o Ontario Library Associ. [Link]


UBC Library Research Guides

Aboriginal Publishers, Distributors & News Media

First Nations & Indigenous Studies

Indigenous Librarianship

 

 

Webcast sponsored by the Irving K. Barber Learning Centre. The Archives Association of British Columbia (AABC) and the Irving K. Barber Learning Centre are pleased to present the webcast roundtable “Talking with First Nations Archives. ” Colleagues who work in local First Nations Archives, Resource Centres and in Records Management programs will share their experiences establishing archives, their role in facilitating access to records, and issues and concerns they encounter on a daily basis.

This event happened on February 23, 2017.


Select Books and Articles Available at UBC Library

Face, M., & Hollens, D. (2004). A Digital Library to Serve a Region: The Bioregion and First Nations Collections of the Southern Oregon Digital Archives. Reference & User Services Quarterly, 44(2), 116-121. [Link]

Lawson, K. L. (2004, November 24). Precious fragments : First Nations materials in archives, libraries and museums (T). [Link]

UBC Library Research Guides

Archival Material

First Nations & Indigenous Studies

Library & Archival Studies

As scholars, we have a critical responsibility to uphold principles such as intellectual honesty, rigour, and open communication. Those who work outside the academy, or whose scholarship spans the academic and non-academic realms, have additional responsibilities and often face more complex or different ethical dilemmas and conflicting moral imperatives in their work. This workshop will feature three experts speaking to the ethical dimensions of scholarship in different contexts: in work involving community engagement or partnership, in the health field, and in the work of ‘public intellectuals’ from any sector.

This event happened on February 16, 2017.


Panelist Speakers

Susan Porter (Dean & Vice-Provost, Graduate and Postdoctoral Studies)
Simon Donner (UBC Geography)
Nina Preto (Ethicist, Provincial Health Services Authority)
Karen Bartlett (School of Population and Public Health)


Select Books and Articles Available at UBC Library

Kipnis, K. (01/01/1999). Ethics: The responsible scholar: Ethical considerations in the humanities and social sciences University of Chicago Press. [Link]

Patterson, B. (2000). Liberal education: An ethos of learning: Forming ethical scholars through experiential education Association of American Colleges. [Link]


UBC Library Research Guides

Education

 

The sequencing of the human genome has been hailed as a scientific breakthrough in that it has opened the human genetic blueprint to investigations of all questions ranging from human origins to the understanding of health and complex diseases. As a result of this revolutionary sequencing of human genomes, our knowledge about how and why we differ from each other as well as how interactions between genes and culture have shaped our community is now more clearly understood. How can this knowledge be used to improve human health through disease prevention, diagnosis and personalized treatment approaches? What does the Genomics Revolution mean for you and your health? What is the potential for future generations?

Join UBC’s Faculties of Medicine, Dentistry and Pharmaceutical Sciences, in partnership with alumni UBC, to hear from five top UBC researchers and learn about the work they are doing to accelerate the genomics revolution which is advancing their fields.

 


Moderator

Dr. Catalina Lopez-Correa

Panelists & Talks

Dr. Jehannine Austin – Genetic counseling: the key to unlocking the potential health and economic benefits of human genomics?

Dr. Martin Dawes – It is not just the genetics that is difficult – the translation to everyday practice is really hard.

Dr. Howard Lim – Personalized Care in Oncology – Pitfalls and Successes

Dr. Corey Nislow – Only in the Light of Evolution: Cells, Organisms, and Pharmacology

Dr. Chris Overall – Can Proteomics Fill the Gap between Genomics and Phenotypes? The Human Proteome Project.


Speaker Biographies

Dr. Catalina Lopez-Correa

Chief Scientific Officer and Vice President, Sectors, Genome BC

catalina-lopez-correa-320x486In January 2016, Dr. Catalina Lopez-Correa joined Genome BC as Chief Scientific Officer and Vice President, Sectors. With over 18 years of international experience in both the academic and private sectors, Dr. Lopez-Correa brings her deep understanding of genomics to the Genome BC leadership team.

Dr. Lopez-Correa holds an MD from UPB University in Colombia, a Masters in Genetics from Paris VII/Pasteur Institute and a PhD in Medical Biosciences-Genetics from KULeuven in Belgium. Most recently she was the Vice-President and CSO, Scientific Affairs, at Genome Quebec where she was instrumental in developing competitive teams for national and provincial research projects, and raising the profile of Genome Quebec on the global stage.

Previous experience also includes a role as Senior Scientist with Eli Lilly and Company. During Dr. Lopez-Correa’s time at Eli Lilly, she was part of the Pharmacogenomics and Translational Medicine Group in charge of discovering and validating genetic/genomic biomarkers in different therapeutic areas (oncology, cardio-metabolic and neurosciences). She also helped develop the company’s tailored therapeutics and personalized medicine strategy. Dr. Lopez-Correa also held the position of Head of Cytogenomics laboratory at deCODE genetics where she developed screening strategies to detect genomic rearrangements. She has also worked for two different American biotech companies in the UK (Genomica and Informax).

Since 2002, Dr. Lopez-Correa has served as evaluator for large multinational projects funded by the European Commission, the IMI (Innovative Medicines Initiatives) and the NIH and has been recognized by several awards nationally and internationally. As part of her commitment to international development, Dr. Lopez-Correa funded the not for profit organization ODNS (Organisation pour le Développement avec des Nouvelles Solidarités) in 2012 and has been involved in several initiatives aimed at demonstrating the impact of genomics in developing countries.

Dr. Jehannine Austin

Associate Professor, UBC Department of Medical Genetics; Canada Research Chair in Translational Psychiatric Genomics; Acting Head, Department of Psychiatry, UBC Faculty of Medicine

 

Genetic counseling: the key to unlocking the potential health and economic benefits of human genomics?

The conditions that are most common in humans (e.g. cancer, psychiatric illness, diabetes, heart disease) are complex – that is,jehannine-austin-320x214 they arise as a result of interactions between genetic and environmental influences. Lifestyle modifications (e.g. quitting smoking, exercise, nutrition) can reduce the risk for these conditions, but studies show that providing people with information about their genetic risk does not reliably provoke adoption of healthy behaviours that can reduce risk. This talk will focus on the role of genetic counseling in personalized prevention approaches to common complex disease by empowering people to act on genomic risk information to engage in risk reduction behaviours.

BIO: Jehannine completed her BSc (Hons, Biochemistry) at Bath University, and her PhD in Neuropsychiatric Genetics at the University of Wales College of Medicine in the UK before completing training as a Genetic Counselor at UBC in 2003. She was first appointed as an Assistant Professor in the Department of Psychiatry in 2007, and in the Department of Medical Genetics in 2008, and was promoted to Associate Professor in 2012.

She holds/has held multiple external salary awards including a CIHR New Investigator Award, a Michael Smith Career Investigator Award, and a Tier 2 Canada Research Chair, and received CIHR’s 2007 Maud Menten New Investigator Award. She is co-author of the book “How to talk with families about genetics and psychiatric illness” (W.W Norton, 2011), Graduate Advisor to the UBC Genetic Counseling program, and a Board Certified Genetic Counselor.

Dr. Martin Dawes

Director & Co-Founder, Personalized Medicine Institute; Head, Family Practice, UBC Faculty of Medicine

It is not just the genetics that is difficult – the translation to everyday practice is really hard.

martin-dawes-320x386There is a journey of using genetic tests to avoid adverse reactions to drugs used commonly in Family Practice. More than half consultations in Family Practice involve complex decisions about medication, adding a genetic test makes things more complex. Dr Dawes and his team had to go back to the drawing board and rediscover how to help patients and professionals identify the safe effective drugs for the individual person.

BIO: Dr. Dawes is the Head of the Department of Family Practice at the University of British Columbia (UBC), and Cofounder of the Personalized Medicine Institute. He started his clinical practice as a family physician in Oxford. Following the completion of his PhD in 1992, he helped develop a Master’s program in Evidence Based Health Care, which allows clinicians to engage in research. He has directed the UK Centre for Evidence-Based Medicine in Oxford and was the head of family practice at McGill University before coming to UBC in 2010. His research includes genomics in primary care and lifestyle interventions to prevent diabetes.

Dr. Dawes is currently leading a new research project entitled “The Implementation of Pharmacogenomics in Primary Care in British Columbia”. This novel project is valued at over $720,000, and is being funded through Genome BC’s User Partnership Program, Rx&D’s Health Research Foundation and other partners. The project will also link in with TELUS Health, the largest electronic medical record (EMR) vendor in Canada.

Dr. Howard Lim

Medical Oncologist, BC Cancer Agency; Clinical Physician Professor, Medical Oncology Division, UBC Faculty of Medicine

Personalized Care in Oncology – Pitfalls and Successes

The use of whole genome sequencing technology to understand tumor biology can be used in the hopes of finding actionable howard-lim-320x480targets for patients with cancer. Dr Lim will provide an overview about how the use of this information can lead to success and how we can learn from the failures.

BIO: Lim is a Medical Oncologist at the BC Cancer Agency Vancouver Centre, specializing in Gastrointestinal Cancer. He is the Program Director of the Medical Oncology Training Program and is the Chair of the GI Tumor Group.

Dr Lim is also an active member of the GI Outcomes Unit, and the Personalized Onco-genomics Program – a clinical research initiative that’s embedding genomic sequencing into the diagnostic and treatment planning for patients with incurable cancers.

Prior to going to medical school, he was fortunate to do research at the BC Cancer Agency Research Centre under Dr. Marcel Bally, in the Department of Advanced Therapeutics. One of the great things that he witnessed was how research could be translated over to patient care seamlessly.

Dr. Lim completed his training in Medical Oncology at the BC Cancer Agency and then did additional training in Gastrointestinal Malignancies at the Oregon Health Sciences University, before coming to the BC Cancer Agency in 2008.

Dr. Corey Nislow

Associate Professor, UBC Faculty of Pharmaceutical Sciences

Only in the Light of Evolution: Cells, Organisms, and Pharmacology

corey-nislow-320x480At its core, all of biology can be considered a combination of the forces of natural selection, organism fitness and the extraordinary results required to meet these two challenges. For the past two decades Dr. Nislow’s lab has sought to understand how genotype is revealed in phenotype; by using diverse models from yeast to man and every environment imaginable. This talk will describe the lessons we have learned from such models and how we are applying them to patients.

BIO: Dr. Corey Nislow’s laboratory uses cutting edge tools to address this central question: how can we understand the biological commonalities in all of the life sciences; from embryonic development, to the spread of infectious diseases to better ways to treat cancer. Each of these disciplines, and in fact all of biology, can be explained in the context of competition, interaction and evolution. Therefore his lab studies the interface between genes and the environment using parallel genome-wide screens, high throughput cell-based assays and next generation sequencing of microbial and human populations. He and his scientific partner, Dr. Guri Giaever shift between model systems to understand how genes and drugs interact during normal and pathological states. Most recently, his lab is exploring how laboratory experiments can co-opt evolutionary processes to understand drug action.

He enjoys teaching all aspects of biotechnology, genomics and drug discovery for undergraduate and graduate students. Corey completed a BA in developmental biology at New College and a PhD in cell and molecular biology at the University of Colorado. He was also an American Cancer Society postdoctoral fellow. He led discovery teams at two biotechnology companies (MJ Research and Cytokinetics Inc., in the San Francisco Bay Area) and at Stanford University. Prior to joining UBC, he was associate professor at the University of Toronto and director of the Donnelly Sequencing Centre.

Dr. Chris Overall

Tier 1 Canada Research Chair, Protease Proteomics & Systems Biology; Professor, UBC Faculty of Dentistry

Can Proteomics Fill the Gap between Genomics and Phenotypes? The Human Proteome Project.

How can only 20,061 human genes encode the complexity of humans when similar numbers of similar genes also encode worms chris-overall-320x480and flys? Mapping and sequencing genes is just the start of this answer. Genes encode proteins and it is proteins that are responsible for forming the cells and tissues of humans. Further, proteins orchestrate the complexity of coordinated signaling between cells and organs that keep us healthy. Dr. Overall will discuss the huge diversity of protein forms, now known as “proteoforms”, and how they lead to the incredible complexity of human cells and tissues. It is through understanding proteoforms that disease mechanisms can be deciphered, new drug targets validated, and accurate diagnostic tests devised that will lead to new medical interventions to treat disease early. By reducing disease and its detrimental outcomes, proteomic biomarkers hold enormous promise to revolutionize diagnostics and personalized medicine ensuring sustainable health care costs.

BIO: Proteases are nature’s biological molecular scissors. Being involved in the fate of every protein—from protein synthesis and maturation, to function changing adaptations in response to changing needs of tissues and cells, and finally in protein removal, proteases are essential to maintaining healthy cells and tissues. Yet, with the good comes the bad. Proteases can dramatically worsen disease and cause tissue destruction leading to disability, pain and death in some diseases like cancer. Thus, Dr. Overall has a long-standing fascination in proteases from his undergraduate days to now. Indeed, he is a Professor and Tier 1 Canada Research Chair in Protease Proteomics and Systems Biology and holds a seven-year $5.55M CIHR Foundation Grant to investigate proteases.

Dr. Overall completed his undergraduate BDS, Honors Science and Masters degrees at the University of Adelaide, South Australia; his Ph.D. in Biochemistry at the University of Toronto; and was a MRC Centennial Fellow in his post-doctoral work with Dr. Michael Smith, UBC, learning protein engineering. On Sabbaticals in 1997-1998 he was a Visiting Senior Scientist at British Biotech Pharmaceuticals, Oxford, UK; and again in 2004/2008 he was a Visiting Senior Scientist at the Expert Protease Platform, Novartis Pharmaceuticals, Basel, Switzerland; and in 2010-2012 was an External Senior Fellow and is now an Honorary Professor, at the Freiburg Institute for Advanced Studies, Albert-Ludwigs Universität Freiburg, Germany.

With over 15,500 citations for his 237 papers he has an h index of 67 and this has been recognized by numerous awards including the 2002 CIHR Scientist of the Year, the UBC Killam Senior Researcher Award (Science) 2005, and several life time achievement awards. He was the Chair of the 2003 Matrix Metalloproteinase Gordon Research Conference and the 2010 Protease Gordon Research Conference. More recently his interests are evolving to deciphering immune deficiencies and chronic inflammatory diseases by the use of proteomics and degradomics, a term he coined. He was elected as Co-Chair of the Human Proteome Organization (HUPO) Chromosome–Centric Human Proteome Project (C-HPP) in 2014 and was recently elected in 2016 to the Executive Committee of HUPO.


Select Books and Articles Available at UBC Library

Current issues in molecular biology: The genome revolution in vaccine research (2004). Caister Academic Press. doi:10.21775/cimb.006.017 [Link]

Hillenmeyer, M., Fung, E., Wildenhain, J., Pierce, S., Hoon, S., Lee, W., . . . Giaever, G. (2008). The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes. Science, 320(5874), 362-365. [Link]

Hofker, M. H., Fu, J., & Wijmenga, C. (10/01/2014). Biochimica et biophysica acta. molecular basis of disease: The genome revolution and its role in understanding complex diseases Elsevier. [Link]

Peixoto, R. D., Renouf, D., & Lim, H. (2014). A population based analysis of prognostic factors in advanced biliary tract cancer. Journal of Gastrointestinal Oncology, 5(6), 428–432. http://doi.org/10.3978/j.issn.2078-6891.2014.081 [Link]


UBC Library Research Guides

Medical Education

Medical Genetics

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