Our lab focuses on the fundamental mechanisms of intercellular communication and neuroimmune responses of the central nervous system (CNS). We are also working to identify key signaling processes and novel therapeutic targets in neurodegenerative diseases, particularly Alzheimer\u2019s disease (AD). We examine the effects of exogenous and endogenous pro- and anti-inflammatory molecules on immune-stimulated model cells of the CNS, and monitor the responses elicited by these molecules using a variety of biochemical assays. By unraveling the intricate signaling processes between neuronal and non-neuronal cells in the healthy brain and under disease conditions, we gain valuable insights into the elusive molecular mechanisms of normal CNS functions as well as neurodegenerative processes.<\/p>\n","protected":false},"excerpt":{"rendered":"
Our lab focuses on the fundamental mechanisms of intercellular communication and neuroimmune responses of the central nervous system (CNS). We are also working to identify key signaling processes and novel therapeutic targets in neurodegenerative diseases, particularly Alzheimer\u2019s disease (AD). We examine the effects of exogenous and endogenous pro- and anti-inflammatory molecules on immune-stimulated model cells … <\/p>\n