International Posters/Presentations

Presenting author is highlighted in bold

• Horne AJ, Fedida D.  (2006) Pharmacological Interaction of Class I Antiarrhythmic Drugs With the Slow Inactivated State of Nav1.5 Channels.  Canadian Physiological Society Winter Meeting. (Presentation)
• Horne AJ, Fedida D.  (2007) Class I Antiarrhythmics Quinidine and Flecainide Interact With the Slow Inactivated State of the Cardiac Sodium Channel.  Biophysical Society 51^st Annual Meeting.  (Poster)
• Horne AJ, Claydon TW, Fedida D.  (2008) Fluorimetric Analysis of the Kv1.2 S3-S4 Linker Shows Differences From Shaker Potassium Channels.  Biophysical Society 52^nd Annual Meeting.  (Poster)
• Horne AJ, Claydon TW, Fedida D.  (2009) Voltage-clamp fluorimetry of Kv1.2 channels show two unique phases of quenching associated with channel activation.  Biophysical Society 53^rd Annual Meeting.  (Poster)
• Peters CJ, Vaid M, Horne A, Fedida D, Accili EA.  (2009) Using Voltage Clamp Fluorometry to Track Voltage Sensor Movement in a Mammalian Kv1.2 Channel in the Presence of the b1.2 Subunit.  Biophysical Society 53^rd Annual Meeting.  (Poster)
• Fedida D, Horne AJ, Eldstrom J, Sanatani S.  (2010) A pore-lining LQT3 sodium channel mutation reveals a kinetic mechanism of AP prolongation and arrhythmia unrelated to changes in inactivation or recovery from inactivation kinetics.  European Society of Cardiology Congress. (Poster)

Published Scientific Articles

Peters CJ, Vaid M, Horne AJ, Fedida D.  (2009) The molecular basis for the actions of Kvbeta1.2 on the opening and closing of the Kv1.2 delayed rectifier channel.  Channels 3(5): 1-9.(Pubmed link)

Horne AJ, Fedida D.  (2009) The use of voltage clamp fluorimetry in understanding potassium channel gating: a review of Shaker fluorescence data.  Canadian Journal of Physiology and Pharmacology 87(6): 411-8 (Pubmed link)

Vaid M, Horne AJ, Claydon TW, Fedida D.  (2009) Rapid outer pore movements after opening in a Kv1 potassium channel are revealed by TMRM fluorescence from the S3-S4 linker, and modulated by extracellular potassium.  Channels 3(1): 1-3 (Pubmed link)

Horne AJ, Peters CJ, Claydon TW, Fedida D.  (2010) Fast and slow voltage sensor rearrangements during activation gating in Kv1.2 channels detected using tetramethylrhodamine fluorescence.  Journal of General Physiology 136(1): 83-99 (Pubmed link)

Horne AJ, Eldstrom J, Sanatani S, Fedida D.  (2011) A novel mechanism for LQT3 with 2:1 block: A pore-lining mutation in Nav1.5 significantly affects voltage-dependence of activation.  Heart Rhythm 8(5): 770-777 (Pubmed link)

Scientific/Research Awards

Prizes (Grad Prizes)

• 2009 Top Poster Award, Graduate Student Category, Anesthesiology, Pharmacology and Therapeutics Research Day
• 2009 Steven Sacks Award (Best PCTH 514 Seminar), Anesthesiology, Pharmacology and Therapeutics Research Day
• 2008 Top Poster Award, Graduate Student Category, Anesthesiology, Pharmacology and Therapeutics Research Day
• 2007 Top Presentation Award, Graduate Student Category, Anesthesiology, Pharmacology and Therapeutics Research Day

Volunteer Writer, CRAM Science/CurioCity

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*Note: Publication dates stated above are those of original publication date; dates listed on the linked articles above reflect date of porting to the current Curiocity page.