Author Archives: Nelson Yu

Biofuels: From You to Toilets to Cars

Have you ever wondered where your human wastes travel to when you flush the toilet? Probably not, I mean why would anyone think about that after doing their “business” in the washroom?  It is common knowledge that what we flush down the toilet end up in the sewers, but where do they go after? Sewage wastes are treated to separate wastewater and sludge. The wastewater can then be further treated to be reused, but what can we do with the remaining sewage sludge? The U.S. Department of Energy’s Pacific Northwest National Laboratory has researched a method to convert sewage wastes to biofuel.

Sewage sludge wastes being transported, courtesy of Wikimedia Commons

Sewage sludge wastes being transported, courtesy of Wikimedia Commons

Biofuels are fuels extracted from biomass, a renewable energy source composed of organic materials. There are many methods to convert biomass to biofuels. The following video provides some background on biofuels and commonly used methods to make them:

Autombile exhaust wastes from fossil fuels, courtesy of Wikimedia Commons

Autombile exhaust wastes from fossil fuels, courtesy of Wikimedia Commons

Biofuels can be a suitable substitute for conventional fossil fuels, coal and gas, when supplying energy to devices and vehicles. The development of biofuels is important for the purpose of reducing the use of fossil fuels. Since fossil fuels produces many wastes when burned. These wastes include air pollution, which is harmful to human health, and greenhouse gases such as carbon dioxide, which contribute to global warming. The use of biofuels can reduce the production of theses harmful wastes.

So how do we convert our human wastes to biofuel. The Department of Energy found that using hydrothermal liquefaction can break down human wastes to simpler chemical compounds. Hydrothermal liquefaction (HTL) is the process of breaking down wet biomass to crude-like oil under high pressure and temperature. In this case the wastes are pressurized to 3,000 pounds per square inch and 300 degrees Celsius. This process gives biocrude and a liquid phase. These parts can be treated to create fuel. Any other solid by-products from the creation of fuel are used for fertilizer, due to high nutrient content.

Personally, I think processing biofuel via sewage wastes is an ingenious method to kill two birds with one stone. Firstly, we produce high quality fuel that can replace fossil fuels. This will lower the production of greenhouse gases and pollution, thus improving the environment. Secondly, it will be very cost-efficient for the government, as any other sewage processing, transport and disposal are no longer necessary. Lastly, this process produces no unusable by-products, as the fuel and remaining organic matter can be used for many purposes.

– Nelson Yu

References:

Fuel from sewage is the future – and it’s closer than you think. http://www.pnnl.gov/news/release.aspx?id=4317 (accessed November 5, 2016).

What are Biofuels?. http://www.conserve-energy-future.com/advantages-and-disadvantages-of-biofuels.php (accessed November 5, 2016).

Hydrothermal liquefaction — the most promising path to a sustainable bio-oil production. https://www.eurekalert.org/pub_releases/2013-02/au-hl020613.php (accessed November 5, 2016).

Under the Helmet

October is finally upon us, therefore ’tis the season of hockey. We Canadians have this strange obsession with hockey. We enjoy the sight of a bone-crushing hit followed by a scuffle between the players involved or the entirety of the two teams. The adrenaline rush we get from watching players tackle each other is exhilarating. However, as we watch comfortably on our couches, the players under the helmet are at risk of obtaining a concussion, leading to neurological side-effects. The professional athletes we watch have many medical specialists tending to their injuries so that the repercussions may be minimized, but what about the young athletes playing in these contact sports?

Figure 1. MLB player, Yadier Molina, after suffering a mild concussion, courtesy of Wikimedia Commons

MLB player, Yadier Molina, after suffering a mild concussion, courtesy of Wikimedia Commons

Dr. Neil Goldenberg and Dr. Patrick Mularoni of John Hopkins All Children’s Hospitial are teaming up with adolescent athletes to investigate methods to treat and diagnose concussion, providing safer conditions for young athletes. The researchers are given a $500.000 grant from All Children’s Hospital Foundation to perform this three-year study.

Firstly, what is a concussion? A concussion is a mild traumatic brain injury (TBI) that causes damage to the brain. Concussions are commonly generated after an impact to that head that quickly shakes the head and brain back and forth.

How a concussion is caused, courtesy of Wikimedia Commons

How a concussion is caused, courtesy of Wikimedia Commons

The Centers for Disease Control and Prevention estimated about 2.5 million people in the United States that visited hospitals for concussion diagnosis. Concussion symptoms vary depending on the severity of the injury; most of the symptoms subside relatively quickly. However, the long term effects require more studies to understand. A brief John Hopkins 2015 study of retired NFL players shows brain injury in the regions that regulate mood and verbal memory. Additionally, the players performed poorly on a memory test.

To prevent the potential long-term effects of concussions and protect young athletes, Dr. Goldenberg and Dr. Mularoni are determined to study changes in the brain functions of athletes in high school. Dr. George Jallo, Director of Brain Protection Sciences at John Hopkins, stated: “It’s very important for us to do a study in adolescents because that’s when their brain is developing and that’s when they’re going to have these head injuries.”

In my opinion, this study is a step in the right direction towards protecting youth in sports. As a former high school basketball player myself, I’ve experienced concussions due to errant elbows to the head. Being a stubborn person, I refused to stop and acted as if I was healthy. Although, I experienced minimal symptoms for a short period of time, it is unknown if the growth of my brain was affected at the time. Since I’ve suffered only one or two concussions it is unlikely to affect me in the long-term, but for the young athletes in hockey and football, contact is abundant, they might suffer through brain injuries that may change their livelihood forever.

-Nelson Yu

References:

Researchers and Athletes Team Up to Study Concussion. https://www.hopkinsallchildrens.org/ach-news/general-news/researchers-and-athletes-team-up-to-study-concussi (accessed Oct.16,2016)

Hedin, M. Johns Hopkins study of retired NFL players sheds light on concussion-related brain damage. http://hub.jhu.edu/2015/01/26/nfl-players-concussion-research/ (accessed Oct.16,2016)

Kivi, R. and Carey, E. Concussion. http://www.healthline.com/health/concussion#Overview1 (accessed Oct.16,2016)

Techniques Preventing Cancer Metastasis in Development

When I was 8 years old, my friend’s mother was diagnosed with breast cancer. Several years later her aunt was also diagnosed with breast cancer. For my friend, developing cancer is not imminent, however the thought of developing cancer is a terrifying idea for her. There is no doubt that almost everyone knows someone in their life who has been diagnosed by cancer, whether it be a family member, a friend, or an acquaintance. In my opinion, to fight against cancer the only way is to entrust the development of cures to the scientific community.

Cancer is menacing disease caused via changes to genes that control the way cells function. In the 21st century cancer has been the most renowned disease. The mortality rate of this disease is no laughing matter as an estimated 1,685,210 patients will be diagnosed with cancer and of those, 595,690 will die during 2016 in the United States alone. While many researchers are feverishly looking for cancer cures that kills cancer, others have been investigating methods to halt cancer from spreading throughout a patient’s body. MIT’s Natalie Artzi, a research scientist at MIT’s Institute for Medical Engineering and Science (IMES), and Tel-Aviv University’s Noam Shomrom have developed a new technique that may help prevent cancer metastasis.

Cancer Metastasis

Cancer Metastasis, courtesy of Wikimedia Commons

Metastasis is the spread of malignant cells from one organ or part of the body to another. Artzi and Shomrom’s new gene therapy technique involves applying microRNAs to cancer tumours. MicroRNAs are cellular RNA fragments that prevents the production of a particular protein. In their research Artzi and Shomrom identified that the protein Palladin plays a key role in the metastasis of breast cancer cells. Their experiments led to the discovery that miR-96 and miR-182, types of microRNAs, decreased the expression of Palladin, thus hampering the cancer cells capabilities to spread.

microRNA

microRNA, courtesy of Andres Zapata https://vimeo.com/52646065

 

With this new gene therapy technique in development, many types of cancers can be halted so long as the correct microRNAs are applied to the cancer sites. I  feel that this research is an immense step towards defeating cancer. Artzi and Shomon’s technique coupled with already known cancer treatments, such as chemotherapy,  can effectively halt the metastasis of early-stage cancer tumours. Thus, potentially saving thousands of patients in the United states, and millions around the world. Nonetheless, cancer would likely never be extinct until a definitive cure is found. However as members of the scientific community, we must do our best in following Artzi and Shomon’s footsetps by developing new techniques and treatments in hopes of saving the lives of people we know.

– Nelson Yu