Tag Archives: research

Does Smoking Keep Colds Away?

Have you ever found yourself sitting near a sneezing stranger, and wonder if you’re going to fall sick next? Do you feel the urge to pull out that pack of cigarettes in your pocket that has been marketed to be good for your health? No! It’s 2018, and research shows that not smoking will increase your chances of fighting a cold.

Good Smoking Ad

Ad for “Healthy Smoking” from Nesster on Flickr.

Specifically, recent research supports that someone can be exposed to the common cold, such as being sneezed on, and not get sick. This happens when your respiratory system is “free” to react to germs in the air before they make you sick.

While the common cold doesn’t sound dangerous, it can lead to complications. According to researchers, millions of colds per year in the US are caused by the rhinovirus and lead to hospitalization. In a recently published article in Cell Reports, Ellen F. Foxman and her team of scientists used two different airway cells from the outer lining of the nose and lungs to observe their responses to rhinovirus exposure and oxidative stress exposure. Oxidative stress exposure is when your body doesn’t have enough antioxidants (which can be obtained from eating antioxidant-rich foods and supplements) to balance out oxidants. Oxidants are molecules that can interact with cells in a good way or a bad way.

Disease Transmission Through Sneezing - Photo from Wikimedia Commons

Disease transmission through sneezing – photo from Wikimedia Commons

The outer layer of the airway normally provides protection from unhealthy parts in the air that gets into the body, including molecules that cause oxidative stress. Foxman’s team studied the protective functions of these cells and found that exposure to oxidative stress increases the cell vulnerability to rhinovirus infection. The study singled out smokers as the patient group the weakest as smoking causes oxidative stress.

Researchers look forward to finding ways to protect against oxidative stress to better defend against rhinovirus infection.

 

-Alyssa Hui

Bioterrorism: An Impending Global Threat

Since antiquity, biological warfare decimated the opposition.  The Assyrians developed fungus that poisoned enemy forces while the Mongols threw fallen soldiers over city walls to spread disease. However, present day treaties and protocols have banned biological weaponry for military use.

Unfortunately, the modern age introduced a new threat: Bioterrorism.

Members of the Japan Ground Self-Defense Force’s Special Weapons Protection Unit (U.S. Marine Corps photo by Lance Cpl. Tyler S. Giguere/Released)

Security agencies around the world struggle to detect biochemical agents. Terrorists can easily create anthrax and smallpox to inflict mass hysteria in enclosed areas such as airports or schools.

Anthrax acts as a potent nerve agent (destroys the body’s nervous system), while smallpox can infect millions of people, killing 30% of those afflicted. Thus, governments have responded by creating defence organizations tasked with combating this emerging threat.

“He who fights with monsters should look to it that he himself does not become a monster.” – Nietzsche

To me, this quote best describes the proper way of fighting back. I believe using destructive weaponry to annihilate terrorists does not make us any better than them. A fine line must exist, that separates us from becoming the very monsters, we fear ourselves.

So far, military research has focused more on prevention over elimination of the enemy. Particularly, in the field of spectroscopy which studies how light interacts with physical objects.

A study done in 2011 by researchers from the Defense Science & Technology Laboratory United Kingdom developed PD-SORS (Point Detection – Spatially Offset Raman Spectroscopy), a new technique that can detect traces of urine hidden in containers from distances of up to 20 cm away. Very similar to the Tricorder from Star Trek (a portable scanning sensor).

SORS works like this: a laser beam fires from a box and hits an object (encased by a barrier) which then scatters around its container before returning back to the box for analysis. A variety of barriers were tested: ranging from paper envelopes, jiffy bags and complex chemical compounds. To great effect, the detector picked up urine traces in all different types of containers!

Raman spectra of drugs. Courtesy of Wikimedia Commons.

Raman spectra of drugs. Courtesy of Wikimedia Commons.

SORS serves a crucial role in defence because traditional Raman spectroscopy excels in transparent and open-air settings. However, most threats hide from the public eye. Terrorists will place dirty bombs in suitcases, jackets and even coffee cups!

The ability to detect sub-surface threats proves invaluable in thwarting potential terrorist attacks. This practical application will allow airport security to improve their efficiency and accuracy when screening for potential threats at checkpoints.

Fighting headstrong may have worked in ancient times, but bioterrorism will require a different strategy. The key lies in prevention, where the greatest victory requires no battle.

Why Your Body Didn’t Fight that Cold

Have you ever found yourself sitting a little too close to a sniffling and sneezing stranger, and wondered if they’re contagiously sick or suffering due to allergies?

Fortunately, recent research supports that someone can be exposed to the common cold, and not get sick. This happens when your respiratory system is “free” to react to the germs in the air before they make you sick, and not fighting other stress from the environment.

Disease Transmission Through Sneezing - Photo from Wikimedia Commons

Disease Transmission Through Sneezing – Photo from Wikimedia Commons

Millions of common colds per year are caused by the rhinovirus. According to researchers, 2 million cases develop into respiratory illness, leading to hospitalization. In a recently published study in Cell Reports, Ellen F. Foxman and her team of scientists used two different airway epithelial cells between the nose and the lungs, nasal and lung cells respectively, to observe their responses to rhinovirus exposure and oxidative stress exposure.

Human Rhinovirus – photo from Flickr

Human Rhinovirus – Photo from Flickr

The outer layer cells of the airway normally provides the body protection from detrimental substances in the air. The study focused on the protective response of these cells further and found that exposure to oxidative stress increases the cell susceptibility to rhinovirus infection. This balance describes the natural compromise between taking viral versus oxidative airway damage. Furthermore, the study singled out smokers as the patient group most susceptible to rhinovirus infection, as smoking causes oxidative stress.

The researchers look forward to finding ways to protect against oxidative stress to better defend against rhinovirus infection.

While the common cold doesn’t sound dangerous, getting sick can lead to complications. These complications add to my long list of reasons to not smoke.

-Alyssa

Is BPA-Free Safe for Me?

I often find myself gravitating towards products that have labels such as “organic”, “cruelty-free”, “free-range”, etc. stuck to their packaging. It’s comforting to know I am opting for a product that is beneficial to either my health, the environment, or both. That’s why when I’m faced with the option to purchase a water bottle that is BPA-free, versus one that is not, 10 times out of 10 I buy the former. For years now I believed this choice was protecting me from the harmful effects of bisphenol A, a chemical known to disrupt reproduction in mice. Much to my surprise, this belief was shattered by a recent article in Current Biology that revealed that the replacement bisphenols are potentially just as harmful.

BPA-free plastic water bottles – photo from Pixabay

Patricia Hunt, a biologist at Washington State University who first discovered the damaging effects of BPA 20 years ago, has uncovered data that mirrors those findings. This new study shows that BPS, a replacement bisphenol, is causing abnormalities in the eggs and sperm of mice. Essentially, BPA-free plastics could still be causing the same adverse effects in humans that led us to ban BPA so many years ago.

The findings were uncovered much in the same way as the BPA discovery decades ago. While conducting unrelated research, Hunt noticed changes in the data collected from her lab mice. Specifically, she found abnormalities in their eggs and low sperm counts. “Given our previous experience with BPA leaching from polycarbonate cages and water bottles,” states Hunt, “damaged materials were an obvious suspect”.

Upon analysis of the plastic cages that the mice were being kept in, Hunt and her team discovered that the inner surfaces to which the mice were being exposed had traces of BPS. The compound, which has replaced BPA in many household items, was being released from the plastic from everyday wear and tear. Notice the similarities between the two chemicals in the images below.

Chemical structure of BPA – photo from Wikimedia Commons

Chemical structure of BPS – photo from Wikimedia Commons

To further investigate the issue, Hunt designed experimental studies in which mice were exposed to several replacement bisphenols. The effects were observed by looking at the number of DNA points where chromosomes had been reshuffled, known as MLH1 foci. This data was telling as MLH1 foci is indicative of the degree of abnormality. Females who were found to have high numbers of MLH1 foci were producing abnormal eggs. On the other hand, males who had low numbers experienced an increase in cell death during sperm creation.

The thought that plastic, a material that we use daily, could be affecting our reproductive health is extremely concerning. The results from Hunt’s most recent studies are remarkably similar to those seen years ago with BPA and raise the question if bisphenols as a class should be eliminated. I hope an alternative replacement in plastics will soon be discovered so that we can still enjoy the diverse benefits of this material.