Multivitamins for health?

Many of us take daily multivitamin or mineral pill. It is convenient and we feel that by doing so, we are getting all the vitamins and minerals our body needs. But is it really beneficial? And is it safe? Let’s take a closer look.

 

Health benefits of multivitamins:

Vitamin and mineral supplements cannot act as a complete food substitute because they can’t provide us with all the benefits that whole foods, such as vegetables, fruits, dairy and whole grains, do. However, many people don’t eat well-balanced diet because they don’t like some type of food, don’t have time or are on a special diet. Therefore, multivitamin and mineral supplements can be used as a way to fill in the gaps in our diet. This can ensure an adequate intake of micronutrients  so our body stays healthy.

According to Dr. Jane Higdon of the Linus Pauling Institute, multivitamin supplements may play a role in prevention of chronic diseases such as heart disease, osteoporosis and cancer. For example, folic acid can decrease risk of cardiovascular diseases and Alzheimer disease and vitamin D and calcium intake promotes healthy bones. Inadequate intake of many vitamins and minerals can cause health issues such as anemia (low red blood cell count) due to iron deficiency or rickets (softening and weakening of the bones) due to vitamin D deficiency.

 

Possible risks and things to watch for:

The most common risk associated with an intake of vitamin and mineral supplements is that of overdosing. Taking too much of some vitamins and minerals can be harmful to your health. For example iron overdosing can cause organ failure and too much of vitamin A can lead to nervous system damage and osteoporosis. Therefore avoid megadoses; don’t take multivitamin and mineral supplements which contain more than 100 percent of the Daily Value of any of the micronutrients. Also, some type of foods, such as cereals or beverages, might be fortified with vitamins so check the labels. You don’t want to get more vitamins than you need.

Always take the vitamin pills with food so that the vitamins can be properly absorbed. For instance, fat-soluble vitamins, such as vitamin A or E, need to be taken with fatty foods, otherwise your body won’t absorb them.
Check the label. Never buy supplements with no expiration dates on them and don’t take vitamins or minerals which are past their expiration date.

Here you can watch an episode from BBC Horizon TV series. It examines if multivitamins are really beneficial to us and if there might be “too much of a good thing” when taking vitamin supplements.

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A few words at the end:

If you need to take multivitamin or mineral supplements because you don’t get enough micronutrients in your diet, choose carefully before you buy. Look at the content as well as the quality verification and when in doubt, consult with your doctor.

Nesim Lichy

How Obesity Reduces Cognitive Skills

Image from: CNN
http://thechart.blogs.cnn.com/2012/10/18/your-brain-on-food-obesity-fasting-and-addiction/?hpt=he_t4

How to live healthy is common interest of all people. However, obesity has limited the movement of living healthy. Due to human tendency to crave sugar and abundant food supply in 21st century, people are getting fat. For example, in the United States and Canada has adult obesity rate is 35.7% and 17% respectively. In the case of the United State, obesity is very serious problem since one third of its entire population is obese. As it is well known, obesity is the main cause of diseases such as heart diseases and high blood pressure levels. However, new study reports that obesity could also impact in lowering brain function. Therefore, this blog is created to illustrate how obesity affects brain function.

Future Obesity Rate in the U.S. (video link)

Researchers at the University of Turku and Aalto University explained how obesity alters brain function. Mid-region of the brain called striatum uses glucose for its metabolism and commands the body to obtain sugars. In obese individuals, striatum is over-activated causing excessive intake of sugars. Meanwhile, increase in activity of striatum decrease prefrontal cortex (front part of brain) function where cognitive function is controlled. Professor Lauri Nummenmma from University of Turku explains cognitive function is suppressed by the overly activated striatum and preventing the body from controlling amount of sugar intake.

Picture retrieved from:
http://www.impactlab.net/2012/10/17/how-diet-affects-brain-function-revealed-in-studies/

Timothy Verstynen reported at the Society for Neuroscience that obesity reduces cognitive function. Verstynen gathered 29 participants with different body mass ranging from normal weight to obese and asked them to solve questions. Based on the brain image of all participants in the study, the brain activity was observed greater in obese group than the lean group to solve the same questions. What this indicates is that obese participants are inefficiently solving a question. Therefore, obese population has more difficult time in solving complex tasks than those of lean population.

Video: How Obesity Affects Brain function in teens (specific case)

The common dieting method among the people is to fast. However, the result is not promising. Tony Goldstone claims that skipping breakfast could result gaining of weight. This is because skipping breakfast activates specific brain region called orbitofrontal cortex, located at the frontal side of the brain. Upon activation, it commands the body to eat high calorie foods. However, having a breakfast lowers the activation and prevents the body from eating high calorie foods. In general, obese population has their orbitofrontal cortex overly activated, craving them for higher calorie foods and preventing from losing weight. Therefore, obesity not only cause gaining of weight but also manipulates the normal brain function.

In conclusion, it is found that being obese does not only cause a heart disease but also reduces the brain function. For example, obese individuals are less efficient in solving a problem than the lean individuals. Therefore, it is very important to have healthy and low calorie foods to keep both brain and body in a good shape.

By Young Ryu

 

Is Immortality at Hand?

I don’t want to die.  Ever.  Don’t ask me what I would do after I would have visited all the countries in the world and watched all the re-runs of Two and a Half Men.  I just don’t want to die.

I’m not the only one.  For as long as history can recall, people have been trying to find ways around death.  Whether it is through religion, alchemy or science, us mortals have been trying to put an end to aging and death.  Today, scientists might actually  be onto something which could give us a shot at immortality.

We know that, in humans, cells reproduce through mitosis, a process in which a cell separates its nucleus’ chromosomes into two identical sets, in two separate nuclei.  In 1961, Leonard Hayflick demonstrated that normal human cells can undergo about 40 to 60 divisions before entering a phases of senescence (that is, before becoming old and losing their ability to divide).  Senescent cells don’t replace themselves with new cells.  They stay in the organism to which they belong, accumulating damage until they reach a point where apoptosis, the process of programmed cell death is reached.  A simple way to put it is that once cells stop reproducing, the body gets older.

But why can cells only divide 40 to 60 times?  It’s because each time cells divide, their chromosomes get chopped off at both ends.  This is fine at first because human cells start off with “caps” of otherwise useless padding of repetitive strings of DNA called telomeres.

Telomere Caps

Human chromosomes (grey) capped by telomeres (white) Source from Wikipedia

As cells undergo successive divisions, the telomeres get shorter and shorter until eventually they are no longer long enough to enable complete and relatively error-free duplication of the genetic information that they encapsulate.

From this, it seems that if we could find a way to ensure telomeres remain long enough, we could have endless cell divisions, be forever young and become biologically immortal.

It turns out that an enzyme called telomerase lengthens the telomeres by adding bits of DNA padding to them.  Moreover, ways to activate telomerase production have been identified.

I should probably nuance the above by saying that there are still many hurdles to be passed before we can get immortality treatment at local clinics.  Cancer features prominently among them.  Indeed, cancers are collections of rogue cells that gained the ability to divide infinitely through some fluke of the telomere / telomerase regulation mechanism.

That being said, we humans can go very far to get what we want and avoid what we don’t.  Many want to avoid death for themselves and those they love.  Thus, I wouldn’t be surprised if we finally got our chance at immortality before I die.

The following video is a podcast from Dr. Ed Park explaining the aging as a result of shortened telomeres.

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For more information on the topic:

http://www4.utsouthwestern.edu/cellbio/shay-wright/intro/facts/sw_facts.html

http://www.viewzone.com/aging.html

Life after death

Trees in cemetery. Image from  Rootsweb.

Trees in cemetery. Image from Rootsweb.

Have you ever thought of continuing life on earth after death? Perhaps as part of a tree? Although there is a wide range of beliefs on afterlife, one thing is certain: your body is staying here on Earth

Cremation

One of the popular burial method is cremation . Statistics has shown that in 2004, America’s national cremation rate is 30.88% and continues to rise year by year. Cremated human remains consist mostly of calcium phosphate, along with minor minerals such as sodium and potassium. Other elements such as carbon and sulphur are released as gases during burning, although a small amount of carbon does remain as carbonate.

How does cremated human remains become part of trees?

Bios Urn. Image from CBC News.

Bios Urn. Image from CBC News.

There are several options on what to do with human ashes, such as keeping it at home, burying it, and sprinkling it over the ocean or land. Recently, industrial designers, Martin Azua and Gerard Moline, have developed a creative, eco-friendly way to dispose cremated human remains. They have designed a biodegradable urn made from coconut shells, compacted peat, and cellulose. This is also known as the Bios Urn. Ashes will be placed inside the urn as well as a seed of a tree. The urn will then be buried. Calcium phosphate is an excellent fertilizer and since human remains are a good source of those, it will fertilize the seed which will germinate and grow into a tree. Best part is, you get to decide what type of tree or plant you want to become part of.

Although trees help the environment by taking in carbon dioxide for photosynthesis, the cremation process also releases a bunch of carbon dioxide. Depending on the size of the body, cremating one corpse can require two to three hours in a furnace generating more than 1,800°F of heat. Environment analysts have calculated that this energy releases 573 pounds of carbon dioxide into the air. Environmentalists have been trying hard figuring out ways to reduce carbon footprint, so imagine the amount of carbon dioxide released each year from just cremation, is it worth it? Would you want to be buried in the Bios Urn?

Here is a video on how cremation works:

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Blog post submitted by: Celine Hsin

Turning tables: a male birth control pill on the horizon.

This is a newsworthy topic I came across earlier this year and thought would be interesting to share…

For years the birth control burden has been placed mainly on women. Female protection for unwanted pregnancy is available in the form of patches, pills, rings, coils, implanted devices… the list goes on! Male contraception, however, is limited and consists of finicky condoms or the permanency of a vasectomy, two methods which have been around since the 1950s.

Despite strong demand, the successful creation of a male contraceptive pill has yet to be realized. While female contraceptives can affect hormones such as estrogen, drug companies have avoided tampering with the male hormone, testosterone, since it can result in a number of unwanted side effects including increased risk of prostate cancer, or breast enlargement (never a good look!).

Recently, a group of researchers led by Martin Matzuk at Baylor College of Medicine and James Bradner at Dana-Farber Cancer Institute, accidentally came across a drug called JQ1 that can inhibit a gene necessary for sperm production, causing testicles to “forget” how to create sperm. This drug has yet to be tested on humans, but showed positive results on mice, with those tested returning to complete fertility once the drug use was fully stopped. Qinglei Li, a member of the research team, states, “it stopped the sperm production very dramatically. More good news is that there appear to be no side effects whatsoever. Once the JQ1 was no longer given to the mice, they were back to their normal reproduction rates, and it did not affect mating behaviour or the health of the offspring.”

According to a study by the Centers for Disease Control and Prevention, in 2006 approximately 49 percent of births in the U.S. were unplanned, despite the birth control options available for women. The introduction of a male birth control pill to the market could potentially lower this rate. Dr. Matzuk and his research team intend to continue their testing and adjust the structure of the drug in order to minimize the chance of any undesirable side effects. Dr. Matzuk believes that the drug will hopefully be available for human use within the next decade.

Although it is an exciting idea for women and men to be able to share the birth control responsibility, the question to consider is whether men would be willing to take such a pill if it were available to them?

Check out this interview with gynaecologist Dr. Sujatha Reddy on how the male birth control pill would work.

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Posted by Jackie Romeyn.

 

Mission Impossible: Red Bull Stratos

Felix Baumgartner moments before attempting his record breaking leap
(Courtesy of Extreme Tech)

Imagine staring down from the heavens and seeing that it could just be moments away. We can only speculate what’s going through the mind of Felix Baumgartner before his death-defying leap. Red Bull created this mission to “Advance scientific discoveries in aerospace for the benefit of mankind.” By doing so, Baumgartner and Red Bull broke three major world records; height reached in a balloon, highest skydive,  and being the first person to travel faster than the speed of sound without a vehicle. Furthermore, years of planning went into this event as some of the most brilliant minds on the planet collaborated to examine the scientific principles involved. Special suits, shuttles, and balloons were to designed to account for the extremities to be encountered.

Felix Baumgartner mid-flight
(Courtesy of Engadget)

“I wanna go fast,” is a quote uttered by almost every child, however Felix Baumgartner got to live this dream as he became the first person to break the sound barrier in free fall. The speed of sound is 1,255 km/h and Baumgartner’s top speed was 1,342 km/h. To put this in perspective, the majority of jets used in the army don’t reach this speed.

Capsule used in the space jump
(Courtesy of Wired)

Nevertheless, breaking the speed of sound is a great accomplishment, but the pressure that high in the atmosphere may have been the biggest threat to Baumgartner’s life. The atmosphere is broken down into multiple layers where the pressure decreases as you go higher. Not only that, the temperature also decreases decreases dramatically with height. Baumgartner was protected from changes in pressure and temperature by his specially designed suit and capsule. The suit and capsule were acclimatized to not allow a change in pressure. If the air pressure in space was equal to the pressure in the suit, all of the liquids in Baumgartner’s body would turn to gas killing him instantly.

A comparison of the balloon used vs the Statue of Liberty
(Courtesy of Geeky-Gadgets)

Now, how is it possible to get a balloon over 120,000 feet in the air? Well, it actually works the same way as when you release a balloon and it flies into the air. However, being 55 stories long, this helium balloon is much larger than anything you can buy at the dollar store.  Helium is able to rise in the air because of a principle called density. As a rule, denser objects fall and less dense objects rise. Since helium is much less dense than the surrounding air it rises. The amount of helium was specifically chosen as that amount will cause the capsule to float around 120, 000 feet.

Below is a video of the event

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With all of this new information the only question is, what’s left. With humans constantly pushing change and technological advancement, there is no limit to what people can accomplish. This story should also serve as an inspiration to others as nothing is impossible.

Written by Arman Gill