Tag Archives: advancement

Mission Impossible: Red Bull Stratos

Felix Baumgartner moments before attempting his record breaking leap
(Courtesy of Extreme Tech)

Imagine staring down from the heavens and seeing that it could just be moments away. We can only speculate what’s going through the mind of Felix Baumgartner before his death-defying leap. Red Bull created this mission to “Advance scientific discoveries in aerospace for the benefit of mankind.” By doing so, Baumgartner and Red Bull broke three major world records; height reached in a balloon, highest skydive,  and being the first person to travel faster than the speed of sound without a vehicle. Furthermore, years of planning went into this event as some of the most brilliant minds on the planet collaborated to examine the scientific principles involved. Special suits, shuttles, and balloons were to designed to account for the extremities to be encountered.

Felix Baumgartner mid-flight
(Courtesy of Engadget)

“I wanna go fast,” is a quote uttered by almost every child, however Felix Baumgartner got to live this dream as he became the first person to break the sound barrier in free fall. The speed of sound is 1,255 km/h and Baumgartner’s top speed was 1,342 km/h. To put this in perspective, the majority of jets used in the army don’t reach this speed.

Capsule used in the space jump
(Courtesy of Wired)

Nevertheless, breaking the speed of sound is a great accomplishment, but the pressure that high in the atmosphere may have been the biggest threat to Baumgartner’s life. The atmosphere is broken down into multiple layers where the pressure decreases as you go higher. Not only that, the temperature also decreases decreases dramatically with height. Baumgartner was protected from changes in pressure and temperature by his specially designed suit and capsule. The suit and capsule were acclimatized to not allow a change in pressure. If the air pressure in space was equal to the pressure in the suit, all of the liquids in Baumgartner’s body would turn to gas killing him instantly.

A comparison of the balloon used vs the Statue of Liberty
(Courtesy of Geeky-Gadgets)

Now, how is it possible to get a balloon over 120,000 feet in the air? Well, it actually works the same way as when you release a balloon and it flies into the air. However, being 55 stories long, this helium balloon is much larger than anything you can buy at the dollar store.  Helium is able to rise in the air because of a principle called density. As a rule, denser objects fall and less dense objects rise. Since helium is much less dense than the surrounding air it rises. The amount of helium was specifically chosen as that amount will cause the capsule to float around 120, 000 feet.

Below is a video of the event

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With all of this new information the only question is, what’s left. With humans constantly pushing change and technological advancement, there is no limit to what people can accomplish. This story should also serve as an inspiration to others as nothing is impossible.

Written by Arman Gill

 

Peanut butter diamonds

Image from http://fashionbride.wordpress.com/2008/10/25/love-is-in-the-diamonds/

Wish that you had some magic ingredients that would enable you to create a diamond that you could afford? Well, you probably already do! Diamonds have been created using only peanut butter as an ingredient. But don’t go running to your pantry too fast- it’s not as simple as that. Although, the majority of us can easily afford our favourite jar of peanut butter, turning this spread into diamond requires a process that is very costly.

 

Diamond formation in mantle
Image from http://geology.com/articles/diamonds-from-coal/

Diamond is an allotrope of carbon, meaning that it is one form in which pure carbon can be found; it is the hardest naturally occurring material found on Earth. Naturally, diamonds are formed under specific conditions. According to Dr. Hobart King, most commercial diamonds are formed in specific areas of the Earth’s mantle. Located just below the Earth’s crust, the mantle is a high-density section of the earth’s interior upon which tectonic plates of the crust flow. The mantle is a very thick layer of the earth (spanning from about 30km to 2900km below the surface); thus, it has a large temperature range of about 870°C to 2200°C. Under these high temperature and pressure conditions, diamonds are formed from carbon sources in the mantle. However, diamond will only form at very specific conditions within the mantle: at temperatures over 1050°C and at depths of approximately 150km below the Earth’s surface. At these depths, humans are unable to obtain the diamond. But, when rare deep-source volcanic eruptions occur, material from the mantle is brought up the surface of the Earth where it can be obtained by us humans. From this, we get diamonds.

 

Discoloured diamond
Image from http://multichrome.blogspot.ca/2012/06/diamonds-from-peanut-butter.html

Professor Malcolm McMahon, of Edinburgh University, has been able to create conditions that mimic the high temperature and pressure conditions of the Earth’s mantle.  McMahon explains that he created these conditions with the ‘stiletto heel effect,’ where in this case, peanut butter was squeezed in between the tips of two diamonds. Using this method, pressures of approximately 45 to 60 kilobars with temperatures of 900 to 1300°C were generated. Peanut butter, being made from primarily roasted peanuts, is a good source of carbon. So under these conditions, McMahon was able to transform peanut butter into diamonds. These diamonds are not perfect, however, as many impurities from the peanut butter cause the diamond to be discoloured. Nevertheless, the diamonds created have previously been on display as they could be a step in the direction of creating cheaper, synthetic diamonds from easily-accessible materials.

 

So, we have been able to create synthetic diamonds in the laboratory; but, currently it would not be economical to create diamonds from peanut butter as creating the conditions required to do this is very expensive. Who knows, maybe one day a cheaper alternative will enable us to do this for less. So appreciate your peanut butter, like the dog in the video below, knowing that it alone can be used to create diamonds!

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Posted by: Angela Johnston

 

Biomarkers in transplantation

A way to predict and diagnose organ rejection without the need for invasive biopsies

Source: http://bit.ly/PTa5tl

For patients with end stage organ failure, transplantation is often the only possible treatment. It involves the replacement of a failing organ with a healthy one from a donor. Although the surgery itself may go smoothly, the patient’s immune system may react to the new organ and reject it.

Biopsy needle.

Biopsy needle.
Source: http://bit.ly/hHKPJP

At present, when doctors want to detect if the recipient’s immune system is attacking the transplanted organ, they take a small sample from the tissue in a procedure called biopsy. Tissue biopsies are costly, painful procedures and in the first year post-transplant, patient would typically undergo around 14 of them. The use of blood biomarkers could decrease or completely eliminate the need for biopsies. The biomarkers would diagnose organ rejection using a simple blood test. This would be a simple and non-invasive method.

Biomarkers explained

In the context of graft rejection, a biomarker is a molecule produced by the action of genes. It can be messenger RNA, a protein or a metabolite, which is produced as a result of body’s immune response. Because people with organ failure express different types and/or quantities of these molecules than healthy people, they can be used as a reliable measure of body’s reaction to the transplanted organ. Their presence can be detected in a blood sample and used as an indicator of the impending organ rejection.

The development of biomarkers is currently underway by the PROOF Centre research team as a part of ongoing movement towards a personalized medicine approach – a patient-centered care providing treatment that is “particularly suited to that patient at that particular time”.

Dr. Scott Tebbutt, Chief Scientific Officer for the PROOF Centre of Excellence, talks about biomarkers:

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Source: http://www.proofcentre.ca/what-is-a-biomarker/

 

For more information about the PROOF Centre and biomarkers, please read here.

Hopes for the future

Laboratory tests currently being used for graft monitoring do not provide a clear measure of immunological risk or accommodation between graft and host. Tissue biopsy thus still remains the primary diagnostic tool for monitoring graft status despite its many limitations. By implementing the use of biomarkers in post-transplant care, researchers hope to completely eliminate or decrease the frequency of biopsies in transplant recipients. Replacing biopsies with a simple blood test would not only reduce patient’s emotional and physical discomfort but would also decrease healthcare costs by preventing disease and improving health.

Submitted by: Nesim Lichy

 

References

1. Biomarkers: A new way to predict and diagnose organ rejection. Transplant Research Foundation of British Columbia Web site. http://www.trfbc.org/site/PageServer?pagename=News_Biomarkers. Accessed 09/20, 2012.

2. Keown PA, McMaster WR, McManus BM. Tools to identify organ rejection and immune quiescence for biological understanding and personalized medical care. Biomarkers in medicine. 2010;4(1):115-121.


A Step Towards Finding Stuart Little?

Unfortunately, scientists have not discovered a rodent that can talk and dresses up as a human. However, they have discovered that rats can experience humanistic emotions and exhibit human characteristics.

The test rat in the process of freeing the imprisoned rat.
Source: http://www.cbc.ca/news/offbeat/story/2011/12/09/rats-empathy-chicago.html

Inbal Ben-Ami Bartal et al. at the University of Chicago have found that rats have the ability to show empathy towards other rats. The research team’s experiment was designed to test whether a rat would open a cage to free another comrade inside. The results showed that the tested rat would free their distressed companion when it hears its calls, regardless of rewards. In order to further test this empathetic behaviour, the researchers performed trials where they placed chocolate in another container nearby to see if the test rat will head to the food instead of the imprisoned rodent. Surprisingly, instead of the anticipated results, the test rat chose to free the restrained rat. Furthermore, instead of hoarding the chocolate, the test rat went as far as to share it with the other.  As such, not only have rats shown empathy in this experiment, they also appear to retain a pro-social behavior towards other rats which is reminiscent of behavior recognized in our culture.

Source: http://rosieheffernan.com/MISC-1

Another finding that exhibits human characteristics found in rats was conducted by Jaak Panksepp, a neuroscientist at Washington State University. He discovered that when tickled, rats emit chirps that are akin to laughter heard through Bat Detectors, a device that can bring high frequencies to our auditory range. These 50 kHz chirps were found to be related to positive affective state in rats (Burgdorf 2011) and can also be heard when the rodents play and chase each other.

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So why should people care whether rats can show empathy or laugh when tickled? These discoveries allow scientists to understand how the brain of specific animal works and its subsequent effect on behavior. Although these studies are focused on rats, the same experimental research may be applicable to other animals as well. This may in turn resolve some of the mysteries of the animal kingdom, from the process that fuels their keen instincts to the impulse that drives certain behaviours.

If further discoveries are made, perhaps we may one day see a genuine Stuart Little that can communicate with us. On the other hand, we might find a duo Pinky and the Brain  and stop them from taking over the world.

Blog post submitted by: Tiffany Ho

References:

Burgdorf, Jeffrey, Jaak Panksepp, and Joseph R. Moskal. “Frequency-Modulated 50 kHz Ultrasonic Vocalizations: A Tool for Uncovering the Molecular Substrates of Positive Affect.” Neuroscience and biobehavioral reviews 35.9 (2011): 1831-6. Print.