Category Archives: Science Communication

Crossed Legs, Health Risk or Not?

How do you usually sit on chairs? Sitting cross-legged is one of my unchanging habits because I feel very comfortable sitting like this. Even now, I have my legs crossed! Is this really harmful to us? Many say crossing legs can lead to numerous health problems even if it may seem harmless. Commonly known consequences of spending long hours with legs crossed are effects on blood pressures and heart, varicose veins, and blood circulation. Check the video below for brief overview.

Credit: Abilhail Abihu

According to the study in 2007, sitting with crossed legs at knee increased blood pressure, whereas with crossed legs at the ankles didn’t result the same. In the study, 50 healthy volunteers and 53 patients with hypertension, abnormally high blood pressure, participated and randomly allocated. Seated blood pressure was measured with their legs in three different positions; one with feet flat on the ground and two with legs crossed differently. During blood pressure measurements, crossing legs increased systolic and diastolic blood pressures in patients with hypertension. In contrast, healthy volunteers had an increased systolic blood pressure, and a little effect on diastolic blood pressure. Blood pressure was higher when seated legs crossed, but it was a temporary increase.

Varicose veins, enlarged veins that are visible through the skin due to increased blood pressure, appear commonly in legs and feet. Age, genetics, obesity, gender, and pregnancy are all risk factors. Dr. Mohmmed Moursi, an UAMS vascular surgeon, indicated that crossing legs isn’t the major cause of this vascular problem. Instead, they result from an intrinsic problem inside the veins. Another common belief he mentioned was that standing for long hours is another cause of varicose veins. Nonetheless, standing may magnify the existing problems with veins but shouldn’t directly cause them.

Varicose_veins

Normal Vein (left) and Varicose Vein (right). National Heart Lung and Blood Institute via Wiki Commons

Many say crossing legs can cause problems for blood circulation but there aren’t many evidences supporting that. Not only sitting cross-legged, but also staying in one position for too long can lead to the numbness in feet. The sensation is from sitting legs crossed which created pressure on the peroneal nerve, located in the back of the knee. People generally change their position when they begin to feel uncomfortable. The recent study in Korea found that sitting legs crossed wasn’t the cause, and in fact, sitting sedentary positions for long time did affect.

Crossed Legs

Women sitting with legs crossed. Ion Chibzii via Wiki Commons

Perhaps, avoiding sitting stationary or improving postures when seated are the solutions. In fact, good posture can improve muscle function, blood flow, lung functions, and mental health. Surprisingly, recent studies showed good posture affects intelligenceimproves abilities to remember, and protects from having back-problems. Thus, sitting with legs crossed isn’t the direct cause but sitting in the same position for long periods of time can be. Exercising regularly, stretching, taking walks in between, and even focusing on sitting up straight can help one change one’s sedentary lifestyle. 

By: Josephina Kim

New AIDS vaccine trials to be performed on Humans for the first time in history

In 1984, Human immunodeficiency virus (HIV) was discovered by a team led by Dr. Roberto Gallo, which opened the gates for mankind in order to gain more knowledge about this deadly incurable disease which was the reason for the deaths of millions of people. As the director of the Institute of Human Virology (IHV), Dr. Roberto Gallo is now launching the institute’s first clinical trial of a vaccine for AIDS – a project that has been 15 years in the making.

HIV is one of a group of atypical viruses called retroviruses that maintain their genetic information in the form of ribonucleic acid (RNA). HIV virus has an enzyme known as reverse transcriptase, which makes it capable of producing deoxyribonucleic acid (DNA) from RNA, whereas most cells carry out the opposite process, transcribing RNA from DNA. The activity of the enzyme enables the genetic information of HIV to become integrated permanently into the genome (chromosomes) of a host cell. Since HIV virus controls the genetic information of the cell, it makes the cell produce more HIV virus using the host machinery, thus replicating at a fast rate. With HIV’s inherent ability to rapidly mutate and escape the immune system, conceiving an effective vaccine against it has been a seemingly difficult challenge.
Mechanism of HIV virus invading a human cell

Mechanism of HIV virus invading a human cell

It is found that when HIV infects a person, its surface protein called gp120 attached itself to another protein called the CD4 receptor, which is found in the white blood cells. When it binds to CD4 cell, it can change shape to avoid recognition from neutralizing antibodies which is the usual immune response form the body. This conformational change allows it to bind to a second receptor called a co-receptor, on CD4 cell surface. Once it has a grip on both HIV envelope protein fuses with the cell membrane, thus once within the cell, HIV is safe from attacks from antibodies. 
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The experimental AIDS vaccine, called as “Full length single chain” vaccine contains an HIV surface protein gp120, engineered to link to a few portions of the CD4 receptor. The main aim is to trigger antibodies against gp120 surface protein when it’s already attached to CD4 and the transitional state in which the protein envelope is present is vulnerable to be attacked, thus effectively stopping it from attaching to the second site of co-factor attachment.
According to World Health Organization (WHO), AIDS has been held responsible for over 1.2 million people in the year 2014, if this vaccine turns out to be effective, it could change the world.
-Rikul Thapar
 

The Benefits of Fad Diets: The Ketogenic Diet

Dieting is one of the hottest topics of the 21st Century, as many different diet plans surface the internet each day. According to the summary by Medical News Today, the most talked about diets include the Atkins Diet,  Zone Diet, Vegetarian Diet, Vegan Diet, Weight Watchers Diet, South Beach Diet, Raw Food Diet, and Mediterranean Diet. Different types of diets are chosen depending on the lifestyle people aim for. However, there is one type of diet that has been raved about in the medical field. The Ketogenic Diet, first developed in the 1920’s to treat epilepsy, has now become a recommended diet for tumor patients.

The Ketogenic Diet and a normal diet differ in the amount of macronutrients eaten. In a normal diet, people eat large amounts of carbohydrates, which is then broken down into glucose by insulin. These glucose molecules are used by cells as an energy source. However, when glucose sources become depleted, normal cells can gain energy through other sources like stored fats. Tumor cells cannot find any other way to gain energy and heavily rely on glucose as the only energy source. Therefore, by restricting the intake level of carbohydrates, the glucose levels become depleted and tumor cells die from a lack of energy source.

carbohydrate-diagram

Structures of glucose and carbohydrates. Credit: Blend Space

The Ketogenic Diet works by restricting the intake of carbohydrates to the lowest amount while increasing the intake of fats and proteins to maintain sufficient energy levels.

ketogenic_diet_flowchart

Credit: Meta Ketosis

The diet typically consists of high fat consumption (70-75% of total calories), moderate protein consumption (20-25% of total calories), and low carbohydrate consumption (5-10% of total calories).

dockers-diner

More bacon please! Credit: Vanity Buzz

The high fat consumption compensates for the low carbohydrate intake. Thus, normal cells begin to breakdown fats for energy. The moderate protein consumption controls the amount of insulin, which further prevents the breakdown of glucose. In addition, high insulin levels restrict ketosis from occurring.

As humans’ main source of fuel, diets play an important role in every individual’s health. As healthy individuals we should follow a regular diet instead of pursuing fad diets. However, special diet plans such as the Atkins Diet is still useful in the medical field for improving the health of tumor patients, and should not be easily overlooked. If you’re interested, please take a look at this video to see how this man beat cancer with the Ketogenic Diet:

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Stephanie Lam

NeuroMythBusters – Breaking Down Issues in Science Literacy

As upper-level students at a renowned university, we often pride ourselves on an excess of scientific knowledge. So let me begin by testing that knowledge base.

True or False:

Children are less attentive after consuming sugary snacks or drinks.

There are distinct types of intelligences, and learners have a unique combination of each.

Left or right brain dominance can result in differences in learning ability.

You may be surprised to learn that the answer to each of these statements is false.

But how? These ideas have been taught by a plethora of teachers, science or otherwise. And based on a study by Paul A. Howard-Jones, many educators do believe that the above statements are scientifically accurate.

Teacher at Chalkboard, via Flickr (cybrarian77)

Teacher at Chalkboard, via Flickr (cybrarian77)

These commonly misunderstood notions, or neuromyths, can be attributed to issues in science literacy and science communication as a whole. I will address a few of these problems as they pertain to the neuromyths above.

1. The use of jargon in surveys and articles

57% of teachers in the UK believe that sugary products make students less attentive. However, studies have proven that there is no connection between sugar and hyperactivity. This idea may be propagated by a difference in understanding – teachers comprehend the word ‘attention’ in terms of behavior compared to neuroscience’s cognitive terminologies. As well, the unnecessarily complex and technical jargon in journals makes it difficult for non-specialists to understand the exact meaning, often leading to oversimplification.

2.  Difficulty in testing

Howard Gardner By Interaction-Design.org [CC BY-SA 2.0 (http://creativecommons.org/licenses/by-sa/2.0)], via Wikimedia Commons

The idea that intelligence cannot be quantified by a single general ability is a popular one. This theory, introduced by Howard Gardner in his book Frames of Mind: The Theory of Multiple Intelligences gained traction because everyone wanted to believe they were smart in some way. A critical review has argued that there is a lack of empirical evidence to support this theory; yet Gardner claims that it was misunderstood. Furthermore, the complexity of the brain makes it nearly impossible to test its legitimacy. When ideas cannot be definitively tested or counter-evidence is not clear, it is easy for the average reader to simply accept ideas.

3. Misinterpretation of graphs and images

H. Garavan, Proceedings of the National Academy of Sciences of the United States of America

Activation of right hemisphere during inhibition control via H. Garavan, Proceedings of the National Academy of Sciences of the United States of America (1999)

Educators are encouraged to determine the dominant side of a learner’s brain in order to teach better. While it is true that different brain regions are preferred for different tasks, the idea of hemispheric dominance has no scientific basis. This neuromyth has been aggressively promoted due to misreading of neuroimagery that shows ‘hot spots’ in the brain. Graphs and images are meant to present information in a straightforward manner; however, non-specialists can be easily led to believe there is a greater significance than what is presented.

So where does this leave us? It is obvious that scientists need to do a better job balancing simplicity and detail, whether it be in the form of words or graphs. Nevertheless, it is encouraging to know that while people may not know a lot about science, they still hold a positive view of scientists and consider scientific progress important. If we can continue to build understanding between science and the public, future generations will develop both skill in critical analysis as well as a fervor for scientific advancement.

Famed astrophysicist Neil deGrasse Tyson on scientific literacy:

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Tim Cheung

Peanut allergy

Image courtesy of: flicker.com

There are different types of food or substances that create allergies in humans. One of the most common allergies is peanut allergy.                                                                                                                   

According to MedicineNet.com, peanut allergy is the allergy which is common among adults and kids, but it usually occurs in children under 3 years old. This kind of the allergy has 80-90% of symptoms are related to skin, for example, skin rash and itching ;despite of that it has some severe symptoms; it affects the respiratory system, gastrointestinal and cardiovascular system; therefore, it might be fatal.

In order for doctors to diagnose patients with peanut allergy, there is a test called skin prick test (SPT). However, if the result is positive, it does not mean that you have peanut allergy and doctors need to take a blood test (peanut specific lgE levels) to make sure that it is peanut allergy.

Good news is that recently, scientists find a cure for this allergy that might save people’s life. In this study, scientists achieve that probiotic treatments will have a positive effect on people who diagnosed with peanut allergy and in the most cases it will protect people from having this allergy reactions.

 Same study shows that probiotics and peanut allergies have negative correlation. Probiotic is a type of bacteria that is beneficial for our health. It will make our immune system strong and has positive effect on our gastrointestinal system and therefore, probiotic treatment is most likely to prevent people from food allergies and more specifically peanut allergies.

watch the following video to find out the details about the effects of probiotic on the peanut allergy.YouTube Preview Image

source:One Post youtube channel

To conclude, if you have already diagnosed with peanut allergy or your kid has this kind of allergy ,instead of being worried about the reactions of your kids to peanuts put probiotics in their daily diet; by using probiotics not only you will save them from fatal reactions to peanuts but also you will make their immune system stronger and therefore, more protective to other diseases. 

Sogand Goharpey