{"id":1142,"date":"2018-04-06T19:48:02","date_gmt":"2018-04-07T02:48:02","guid":{"rendered":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/?p=1142"},"modified":"2018-04-06T19:48:02","modified_gmt":"2018-04-07T02:48:02","slug":"origion-of-the-kwaday-dan-tsinchi-man-inferred-through-mitochondrial-dna-analysis","status":"publish","type":"post","link":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/2018\/04\/06\/origion-of-the-kwaday-dan-tsinchi-man-inferred-through-mitochondrial-dna-analysis\/","title":{"rendered":"Origion of The Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi Man Inferred Through  Mitochondrial DNA Analysis"},"content":{"rendered":"<p><span style=\"font-weight: 400\">\u00a0 \u00a0 Just imagine, a group of hunters comes across a mummified ice body aged hundreds of years old and you might just be related to this ancient artifact. One may be skeptical about how this unknown body can possibly be related to, but in this day and age science and technology have opened the doors to many extraordinary phenomena, including the analysis of <a href=\"https:\/\/ghr.nlm.nih.gov\/primer\/basics\/mtdna\" target=\"_blank\" rel=\"noopener\">mitochondrial DNA<\/a> (mtDNA) to trace the descendants of unknown bodies like the famous<a href=\"http:\/\/www.ancient-origins.net\/history\/long-ago-person-tracking-canadian-ice-man-006580\" target=\"_blank\" rel=\"noopener\"> Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi<\/a>, also known as the Canadian Iceman. \u00a0<\/span><\/p>\n<div id=\"attachment_1143\" style=\"width: 310px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1143\" class=\"wp-image-1143 size-medium\" src=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/excavating-300x199.jpg\" alt=\"\" width=\"300\" height=\"199\" srcset=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/excavating-300x199.jpg 300w, https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/excavating.jpg 377w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><p id=\"caption-attachment-1143\" class=\"wp-caption-text\">Excavation of the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi in BC. Source: Sarah Gaunt (CAFN)<\/p><\/div>\n<p><span style=\"font-weight: 400\">\u00a0 \u00a0 Maria Monsalve, a senior instructor for the Faculty of Medicine at the University of British Columbia, completed her post-doctoral training at the University of Cambridge on ancient remains. Her interest and love for mummies allowed her and her colleagues\u2019 proposal from being the first to be chosen to study the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi\u2019s tissue samples. Dr. Monsalve\u2019s breakthrough using mtDNA analysis of the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi was used to trace back many of the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi\u2019s common descendants.<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u00a0 \u00a0We had the opportunity to interview Dr. Monsalve about her research on the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi to clarify some of the complex concepts and techniques that were used during her study. In this video, Dr. Monsalve describes how she was able to come across working with the tissue samples of the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi as well as the advantages of using mtDNA analysis for investigating ancient preservations. \u00a0<\/span><\/p>\n<p><iframe loading=\"lazy\" title=\"SO Project Video\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/OhWuS-qPWU4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p><span style=\"font-weight: 400\">\u00a0 \u00a0It is well known that DNA can provide a variety of information regarding the past and present history of one\u2019s family tree but the testing of mtDNA for the analysis of forensic samples is quite striking and unexpected. Mitochondrial DNA has multiples copies, unlike nuclear DNA which only has a single copy. This allows mtDNA to be incredibly useful for forensic analysis of ancient remains since the probability of mtDNA from being degraded from weather factors such as UV radiation and humidity is much lower than nuclear DNA. Not only does having several copies of mtDNA allow it to be highly useful when investigating ancient tissue samples, but the maternal transmission of mtDNA allows the common mtDNA lineage to be used to trace back the common descendants of ancient mummies.<\/span><\/p>\n<div id=\"attachment_1146\" style=\"width: 279px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1146\" class=\"size-medium wp-image-1146\" src=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/mtdna-269x300.jpg\" alt=\"\" width=\"269\" height=\"300\" srcset=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/mtdna-269x300.jpg 269w, https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/mtdna.jpg 300w\" sizes=\"auto, (max-width: 269px) 100vw, 269px\" \/><p id=\"caption-attachment-1146\" class=\"wp-caption-text\">Mitochondrial DNA (mtDNA). Source: Wikipedia<\/p><\/div>\n<p><span style=\"font-weight: 400\">\u00a0 \u00a0Through this podcast, Dr. Monsalve thoroughly describes the precautions and steps that were used when extracting and sequencing the mtDNA lineage of the tissue samples of the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi in the UBC pathology lab.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1151\" src=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/audioclip-1523035268-1.jpg\" alt=\"\" width=\"1\" height=\"1\" \/><\/p>\n<div class=\"wp-playlist wp-audio-playlist wp-playlist-light\">\n\t\t\t<div class=\"wp-playlist-current-item\"><\/div>\n\t\t<audio controls=\"controls\" preload=\"none\" width=\"478\"\n\t\t\t><\/audio>\n\t<div class=\"wp-playlist-next\"><\/div>\n\t<div class=\"wp-playlist-prev\"><\/div>\n\t<noscript>\n\t<ol>\n\t\t<li><a href='https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/final-podcast-MP3.mp3'>Podcast Group 6 Dr.Monsalve<\/a><\/li>\t<\/ol>\n\t<\/noscript>\n\t<script type=\"application\/json\" class=\"wp-playlist-script\">{\"type\":\"audio\",\"tracklist\":true,\"tracknumbers\":true,\"images\":true,\"artists\":true,\"tracks\":[{\"src\":\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/files\/2018\/04\/final-podcast-MP3.mp3\",\"type\":\"audio\/mpeg\",\"title\":\"Podcast Group 6 Dr.Monsalve\",\"caption\":\"background music licensed through itunes\",\"description\":\"\",\"meta\":{\"length_formatted\":\"5:14\"},\"image\":{\"src\":\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-includes\/images\/media\/audio.svg\",\"width\":48,\"height\":64},\"thumb\":{\"src\":\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-includes\/images\/media\/audio.svg\",\"width\":48,\"height\":64}}]}<\/script>\n<\/div>\n\t\n<p><span style=\"font-weight: 400\">\u00a0 \u00a0Although Dr. Monsalve has limited time, the phenomena of mtDNA allowed her and her committee to find <a href=\"https:\/\/thegeneticgenealogist.com\/2008\/04\/27\/kwday-dn-tsnchi-long-ago-person-found\/\" target=\"_blank\" rel=\"noopener\">17 descendants in the BC area that was related to the Kw\u00e4day D\u00e4n Ts&#8217;\u00ecnchi.<\/a> It is technology and breakthroughs like this that allows us to investigate the past and present wonders of life and give a glimpse of what life might have been like hundreds of years ago.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Project by: Jasmine Hyun, Linjian Li and Ran Bi (Group 6)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u00a0 Just imagine, a group of hunters comes across a mummified ice body aged hundreds of years old and you might just be related to this ancient artifact. One may be skeptical about how this unknown body can possibly &hellip; <a href=\"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/2018\/04\/06\/origion-of-the-kwaday-dan-tsinchi-man-inferred-through-mitochondrial-dna-analysis\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":57082,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[132756,431980,132763,132758,431983,3151391],"tags":[3462628,2992,3462965,3463315,3462833,717144],"class_list":["post-1142","post","type-post","status-publish","format-standard","hentry","category-biological-sciences","category-outreach-project","category-public-engagement","category-science-communication","category-science-communicators","category-science-in-news","tag-ancient-remains","tag-biology","tag-canadian-iceman","tag-family-tree","tag-kwaday-dan-tsinchi","tag-mitochondrial-dna"],"_links":{"self":[{"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/posts\/1142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/users\/57082"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/comments?post=1142"}],"version-history":[{"count":11,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/posts\/1142\/revisions"}],"predecessor-version":[{"id":1189,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/posts\/1142\/revisions\/1189"}],"wp:attachment":[{"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/media?parent=1142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/categories?post=1142"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.ubc.ca\/communicatingscience2017w211\/wp-json\/wp\/v2\/tags?post=1142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}