Tag Archives: parkinson’s disease

Singing to Treat Parkinson’s Disease: It Works!

Do you know someone that has Parkinson’s Disease? Did you know that there are more than 10 million people around the world that suffer from this disease, but there is still no cure?

A recent study has discovered what could be a therapy for Parkinson’s Disease, but it is quite unconventional! Keep reading to find out more.

To provide some background information, Parkinson’s Disease (PD) is a “neurodegenerative disorder”, which means that it causes serious damage to the nerves of the brain. Symptoms of the disease include hand tremors, extreme difficulty walking as well as mental problems such as hallucinations or delusional thoughts. The disease typically affects people over the age of 50.

Diagram of the “Basal Ganglia”, which is the part of the brain affected by Parkinson’s Disease. Source: Wikimedia Commons. This image is part of the public domain.

Now, the good news! A group of researchers at Iowa State University have been investigating the effects of singing therapy on a group of PD patients, and found that the participants’ heart rate, blood pressure, as well as self-reported anxiety and sadness decreased over the 2.4-year-long treatment period. These results show that the overall health and well-being of the participants improved as a result of the therapy!

What is “singing therapy”, you ask? Essentially, the treatment is weekly or bi-weekly, and consists of sessions in which the PD patients undergo vocal exercises and sing well-known songs as a group. Researchers found that the PD patients were able to breathe more effectively after the therapy!

You might be wondering how singing could possibly affect such a complicated disease, but as lead investigator Elizabeth Stegemoller describes it,

“We’re not trying to make them better singers, but to help them strengthen the muscles that control swallowing and respiratory function. We work on proper breath support, posture and how we use the muscles involved with the vocal cords, which requires them to intricately coordinate good, strong muscle activity.”

Essentially, singing therapy is beneficial to PD patients because it helps them strengthen the muscles used for swallowing and breath control, which are tasks that become difficult with the onset of the disease.

In addition to these benefits, the study found that the patients experienced improvements in their tremors and walking.

A depiction of a PD patient drawn by neurologist Sir William Richard Gowers in 1886. This image is currently used by the medical community as a reference for the symptoms of PD. Source: Wikimedia Commons. This image is part of the public domain.

Looking to the future, researchers are hopeful that singing therapy will be implemented as a clinical treatment for PD patients, as it is cheap, extremely low-risk, and lots of fun!

YouTube Preview Image

Watch this YouTube video (published by Iowa State University and available as part of the public domain) to find out more about the Parkinson’s Disease research being conducted by Elizabeth Stegemoller at Iowa State University.

Maya Liepert

Slow and Steady: New Research Claims That Removing The Appendix Decreases Risk of Parkinson’s Disease

Many people have a friend or family member who is afflicted by Parkinson’s Disease, a long-term degenerative disease affecting the brain’s central nervous system. Seemingly unrelated, many people also have removed their appendix, a small finger-like length of intestine that is widely removed due to appendicitis. Perhaps somewhat unexpectedly, a recent study analyzing more than 1 million people in Sweden has concluded that an appendix removal done decades ago may reduce the chances of developing Parkinson’s Disease (PD).

Scientists speculate that the removal of the appendix affects the development of an abnormally formed protein, named α-synuclein (alpha-synuclein), which is present in PD patients.

What Is Parkinson’s Disease?

Parkinson’s Disease is a genetic neurological (brain) disorder that can have significant impact on the physical and mental state of patients, with more than 55,000 Canadians diagnosed with PD. The onset of PD is slow, often alongside symptoms such as hand tremors and body stiffness.

Parkinson’s encompasses a wide subset of symptoms and related complications: restricting the movement of a patient gradually, eventually initiating other symptoms such as difficulty speaking, loss of coordination, and development of depression.

Prevalence of Parkinson’s disease in household population, by age group and sex, population aged 45 or older, Canada excluding territories, 2010/2011 Source: StatCan

Presence of α-synuclein In PD Patients

A protein called α-synuclein, in its misfolded (mutated) form, is fairly abundant in the appendix of both healthy people and PD patients. The mutated version of α-synuclein has the same structure as the version of α-synuclein that is found in the brains of patients afflicted by PD, which scientists have suggested causes PD by damaging the brain cells which control bodily movement.

Highly magnified image of mutated α-synuclein.
Source: Van Andel Research Institute

α-synuclein tends to travel from the appendix, leading scientists to investigate whether the protein present in the appendix is the same as the protein in the brain of PD patients.

Study on More than 1 Million Swedes Found…

Knowing this information about α-synuclein, Viviane Labrie (the first author of the study) and her team at the Van Andel Research Institute in Michigan analyzed 1.6 million Swedish medical records to find that appendix removal showed almost a 20% decrease in chances of developing PD.

The data analysis also showed that an appendix removal also delays the diagnosis of PD for the people in the data set who did go on to develop PD for more than 3 years.

Why Is This Important? 

Parkinson’s Disease is not only a devastating and debilitating disorder, but also it is increasingly common as the general population begins to age. In recent years, PD is affecting more than 60,000 people each year in the United States. As PD is the second most common neurodegenerative (brain disorder) disease in Canada, it is with hope that these findings will inspire investigations into the pursuit of a treatment for Parkinson’s Disease.

See below for a video posted by Parkinson Society of BC, showcasing a young patient and her goals despite her disorder.

An instalment of Parkinson Society of BC’s This Is Parkinson’s Disease campaign, sharing Hilary’s story: a real-life British Columbian living with PD.
Source: Parkinson Society of BC

-Allison Chiang