{"id":30,"date":"2012-03-27T00:16:52","date_gmt":"2012-03-27T07:16:52","guid":{"rendered":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/?page_id=30"},"modified":"2012-04-03T16:45:13","modified_gmt":"2012-04-03T23:45:13","slug":"conclusion","status":"publish","type":"page","link":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/conclusion\/","title":{"rendered":"> Conclusion"},"content":{"rendered":"<p><a title=\"Vengador by fotos.rotas, on Flickr\" href=\"http:\/\/www.flickr.com\/photos\/fotosrotas\/2730765130\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright\" style=\"border-image: initial; border-width: 1px; border-color: black; border-style: solid;\" src=\"https:\/\/farm4.staticflickr.com\/3110\/2730765130_baf50fab04_n.jpg\" alt=\"Vengador\" width=\"175\" height=\"246\" \/><\/a>As it currently stands, <em>in silico<\/em>\u00a0methods such as creating predictive and expert models still require further development before it can be widely accepted by \u00a0both the regulatory and the scientific community.<\/p>\n<p>For an <em>in silico<\/em>\u00a0method to replace an animal test method, major steps include:<\/p>\n<ul>\n<li>test development<\/li>\n<li>prevalidation<\/li>\n<li>validation<\/li>\n<li>peer reviews<\/li>\n<li>regulatory acceptance<\/li>\n<\/ul>\n<p>Hopefully, systems similar to the European Centre for the Validation of Alternative Methods (ECVAM) will be established worldwide. Such systems focus on developing and incorporating <em>in silico <\/em>\u00a0methods with <em>in vitro<\/em>\u00a0methods to create integrated processes to reduce the reliance on <em>in vivo<\/em>\u00a0animal tests.<\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/blogs.ubc.ca\/computationaltoxicology\/files\/2012\/03\/lolcat1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-171\" style=\"border: 1px solid black;\" title=\"lolcat1\" src=\"https:\/\/blogs.ubc.ca\/computationaltoxicology\/files\/2012\/03\/lolcat1-295x300.jpg\" alt=\"\" width=\"295\" height=\"300\" srcset=\"https:\/\/blogs.ubc.ca\/computationaltoxicology\/files\/2012\/03\/lolcat1-295x300.jpg 295w, https:\/\/blogs.ubc.ca\/computationaltoxicology\/files\/2012\/03\/lolcat1-59x59.jpg 59w, https:\/\/blogs.ubc.ca\/computationaltoxicology\/files\/2012\/03\/lolcat1.jpg 492w\" sizes=\"auto, (max-width: 295px) 100vw, 295px\" \/><\/a><\/p>\n<p style=\"text-align: center;\">Basically, less animals used in research = more cute animal pictures!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As it currently stands, in silico\u00a0methods such as creating predictive and expert models still require further development before it can be widely accepted by \u00a0both the regulatory and the scientific community. For an in silico\u00a0method to replace an animal test method, major steps include: test development prevalidation validation peer reviews regulatory acceptance Hopefully, systems similar [&hellip;]<\/p>\n","protected":false},"author":12467,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-30","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/pages\/30","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/users\/12467"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/comments?post=30"}],"version-history":[{"count":13,"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/pages\/30\/revisions"}],"predecessor-version":[{"id":128,"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/pages\/30\/revisions\/128"}],"wp:attachment":[{"href":"https:\/\/blogs.ubc.ca\/computationaltoxicology\/wp-json\/wp\/v2\/media?parent=30"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}