Case Study 1

The Genetics of Resistance to HIV Infection

This case uses the example of HIV, to explore the relationships between viruses, cells and the immune system, and the role of genes in disease resistance. An animation explains PCR (polymerase chain reaction) and electrophoresis and their practical use as a genetic test.

We will see how mutations in an HIV receptor confer relative reslstance to infection. We will find out how often this mutation occurs in the general population, and see data about additional mechanisms of HIV resistance.