Once piece of factual knowledge that I acquired since the start of the course is that the \u201cadd something\u201d experimental approach is a test of sufficiency for a result that we wish to induce. For example, we may want to know if adding certain transcription factors to differentiated cells can induce the cells to become pluripotent.<\/p>\n
This new piece of knowledge fits into what I already knew by providing an additional method of studying the functions of genes. Previously, I was more familiar with the \u201cremove something\u201d approach for studying genetics because I volunteer at a lab where experiments are often done by using a wild-type strain as a control group and a knockout strain as an experimental group. In my experience, I have never used the \u201cadd something\u201d approach in the lab, so I consider it to be an interesting alternative way to perform experiments.<\/p>\n
One thing that comes to mind when thinking about the \u201cadd something\u201d approach is using CRISPR as a means to do the \u201cadding\u201d. I often hear about how CRISPR can be used to add or edit genes, but I do not know very much about how CRISPR actually works. I would be interested in learning more about CRISPR in BIOL 463.<\/p>\n
In my opinion, the \u201cadd something\u201d approach fits into the general concept of using experimental approaches to obtain information. Earlier in this journal, I mentioned the \u201cremove something\u201d approach as another experimental approach used to obtain information. Furthermore, in class, we also discussed the \u201clook\u201d approach as yet another experimental approach. Thinking about the concept of experimental approaches in general, I am curious about other approaches that may be possible which allow scientists to obtain information in different ways. Just like how the \u201cadd something\u201d approach is a test of sufficiency and the \u201cremove something\u201d approach is a test of necessity, I wonder how other approaches can provide information in other ways.<\/p>\n","protected":false},"excerpt":{"rendered":"
Once piece of factual knowledge that I acquired since the start of the course is that the \u201cadd something\u201d experimental approach is a test of sufficiency for a result that we wish to induce. For example, we may want to … Continue reading