Event Schedule

2025 URS Schedule:

Time Main Room – LSC 1 Secondary room – LSC 2
8:30-9:00 Sign-in and poster pin-ups
9:00-9:15 Opening statements
9:15-10:15 Rapid Fire Talks – 8 Total (see below)
Co-op Projects
10:15-10:30 Chimeric Antigen Receptor (CAR) Regulatory T-cell (Treg) therapy could control rejection of hiPSC-CM grafts, a promising heart failure treatment

Phoebe McNair-Luxon

10:30-10:45 Development of a human monocyte-derived macrophage assay to screen for anti- and pro-inflammatory compounds using whole blood stored at room temperature for more than 48 hours

Michaela Grace Monachello Schweitzer

10:45-11:00 Designing Islet-specific TCR Tregs for Type 1 Diabetes

Emily Sie Yan Leong

11:00-11:15 Break
Directed Studies Projects
11:15-11:30 Bowel preparation facilitates pathogen colonization in an intestine-on-a-chip model

Brian Deng

The Stress Test: Assessing Gut Microbial Replication via PCR Assay

Asmita Jain

11:30-11:45 Helminth infection elicits sex specific microglia differences in a multiple sclerosis mouse model

Susan Zhang

Gut barrier disruption is observed in experimental autoimmune encephalomyelitis and manifests as systemic inflammation modulating the activity of microglia in the mouse brain

Burak Ozkan

11:45-12:00 Intestinal microbiome-modulation of microglia in the developing brain

Shreya Gandhi

Discovery and In vitro Characterization of Two Novel Human TMPRSS2 Inhibitors as Leads to Potential Drugs Against Influenza A (H1N1) Viruses

Michelle Ho

12:00-1:00 Lunch and Posters
1:00-2:00 Keynote: Dr. Megan Levings
Directed Studies and Course-based Undergraduate Research Experiences
2:00-2:15 Engineering gp70 chimeric autoantigen receptor T cells using MRL/lpr derived cells

Elizabeth Adefolaju

Expression of Truncated SurA Potentially Disrupts BrkA Maturation in Escherichia coli

Andrew Huang, Aivi Tran, Cyrus Yong, Thomas Yeung

2:15-2:30 Investigating the influence of the BrkA autochaperone region on recombinant protein surface expression and activity

Gabi Reznik, Artemis Melville-Bowser, Miles Da Silva, Natalia Blanco

 Type 1 fimbriae may sterically hinder Antigen 43-mediated autoaggregation in Escherichia coli

Catherine Pepin, Brian Deng, Alex Pei, Lester Cheng

2:30-2:45 Autodisplay of the Burkholderia cepacia lipase and its chaperone foldase using the BrkA autotransporter system

Mya Bal, Monica Leca, Samantha Tang, Delphine Zhou

Development of a Model for Intimin Expression and Detection at the cell surface of Escherichia coli BL21

Carolyne You, Asha Octoman, Claire Rollins, Nicholas Taraviras

2:45-3:00 Utilizing BrkA passenger domain to surface display lead remediator EC10 on Escherichia coli

Norman Li, Renee Li, Arshia Tavangar, Le Qi Chen

Expanding Biocatalytic Applications: Surface Display of Dimeric Sorbitol Dehydrogenase Using BrkA Autotransporter

Kerry Shi, Kristen Tien, Carleton Young, Ashine Zhang

3:00-3:15 Evaluating the impact of geneX and BrkA expression on outer membrane stability in Escherichia coli

Jeyah Cruz, Joshua Lin, Georgia Langdon, Victoria Rogers

Chaperone protein SurA may be necessary for the secretion of BrkA in E. coli BW25113 during the stationary phase

Melika Hajimohammadi, Salva Sherif, Joshanne Palces, Rana Ghadymimahani

3:15-3:30 Ag43-Mediated Autoaggregation of Escherichia coli Requires the Passenger and the Autochaperone Domains but In Vitro Passenger Domain Folding and Self-Interaction Does Not Require the Autochaperone Domain

QingRu Kong, Keheng Wang, Ran Tao, Zurui Zhu

Developing a Chloramphenicol-Selectable Cpx Stress Reporter and Investigating BrkA-Induced Envelope Stress in E. coli strain BW0052

Arian Afshari, Amy Kim, Ramdeep Kailay, Sherinay Xierenayi, Mohammed Akif

3:30-3:45 Captivity reduces gut microbial diversity and metabolic pathway abundance across mammals with different diet and gut fermentation types

Tiffany Wu

Sociodemographic Factors have Nuanced Effects on Gut Microbiome of Human Immunodeficiency Virus Patients in Zimbabwe

Tien Do, Steven Chen, Savitha Singarajan, Thomas Yuen, Susana Chung Wang

3:45-4:00 Stretch break  
4:00-4:20 Final Remarks and Prizes

3×1 Presentations (aka Rapid Fire Talks)

1 Interaction between salmonids symbiotic microbial communities and their environment

Jasmilan Saini

2 Understanding the role of urobiome-derived lysophosphatidic acid in renal tubular epithelial cell and barrier functioning

Pailin Cui

3 Peritonitis Model Development to Assess the Efficacy of Cationic Liposomes Containing TLR7/8 Agonists (Resiquimod) in Combination with Antibiotics

Tien Do

4 An Examination of the Intracellular Domain of NCAM-1 and Its Phenotypic Effects on RIG-3 Mutations in Caenorhabditis elegans

Charlotte Lee

5 Development and validation of a serum bactericidal antibody assay to evaluate functional antibody responses against Klebsiella pneumoniae

Sina Hakimpour

6 Exploring the Accessibility of Functionally Important Conserved Epitopes on Prefusion-Stabilized SARS-CoV-2 Spike

Paria Sokhanran

7 Impact of Integrase Strand Transfer Inhibitor Treatment on the Gut Microbiome of People Living with HIV

Edward Sobczak, Jordan Drotsky, Emily Huang, Emily Wiebe

8 The Type 3 Immune Response: A Hero or Villain in Crohn’s Disease?

Mya Bal