Writing a Journal Article
Introduction (from general-specific)
1. Set the context and background – What’s the problem?
2. What is the scientific/clinical/public health importance of this problem?
3. Demonstrate the gap in research to date, i.e. what makes your work unique – no one has done it before.
4. Objectives – State the specific research question you are addressing.
Methods
o Name the study design.
o Describe exposures of interest and primary and secondary outcomes. Justify these.
o State hypotheses.
o Describe inclusion and exclusion criteria.
o Describe study setting
o Include power calculations
o Describe analysis plan. Name variables that you will be evaluating as potential confounders and effect modifers.
Results
o Describe number of subjects in comparison groups, rate of participation among eligible subjects.
o Compare baseline characteristics of comparison groups. This material will be in Table One –give an overview in the text.
o Describe findings – make your primary and secondary outcomes clear.
o Present adjusted and non-adjusted estimates of risk (Table two).
o Findings from subgroup analyses if relevant.
Discussion (from specific general)
o Summarize your main findings—What is the punch line?
o Explain findings – what was the mechanism linking outcomes to exposure?
o Use Hill’s criteria for causality to explore if this is a causal relationship: biological gradient, temporality, consistency with other findings, strength of association (size of RR, OR), biological plausibility, coherence with what is known about the subject.
o Discuss study imitations (with a rebuttal). Think one step ahead of the reviewer.
o Conclusion
o Implications for practice, if relevant.
o Recommendations for future research.
Read Journal of the American Medical Association, American Journal of Epidemiology, New England Journal of Medicine, and Lancet as examples of good writing.