Category Archives: Biological Sciences

A “Smart” Way of Eating

You may know that it is a good idea to eat fruits and vegetables to keep healthy; you may know that we can lose weight by controlling the calories input. But do you know that we can simply stay healthy and lose weight by having a “smart” eating pattern while not changing what we eat? What does the eating pattern mean in this case?

Different eating patterns including a regular way and a non-traditional way –TRF, which stands for time-restricted feeding. TRF simply means we restrict the total amount of time of food consumption every day. The time spread of the regular eating pattern is usually 16 hours. But if we eat the same amount of food but reduce the total time spread to less than 16 hours, we can easily stay healthy and even lose weight by maintaining a relatively stable heartbeat.

The figure below can better explain different eating patterns.

[source: http://www.pnas.org/content/pnas/111/47/16647/F3.large.jpg]

As the five figures are shown above: the blue area of the circle represents the daytime and the black area represents the night time. The regular eating pattern is shown as the pattern A. It includes three large meals plus snacks during a 16-hour period of wakefulness. Pattern B, C, and D illustrate the concept of TRF, which is what we recommend in this article. The common idea shared among the TRF eating patterns is the limited eating time — the total time spread of food consumption is less than 16 hours.

To be more specific, eliminating midnight snack and limiting eating to 12 hours is the “smart” eating pattern that we are encouraged to have. A research conducted by Tina Hesman Saef found that fruit flies with only 12-hour spread had steadier heartbeats in old age than flies with unrestricted eating time.

[source: www.sciencenews.org/sites/default/files/main/articles/ti_fly_feeding_graph.png]

The experiment was designed to have two groups of flies. One group ate a cornmeal diet anytime they want; another group had access to same food for 12 hours only. Both groups ate about the same amount of food and had similar amounts of activity. The result of the research shows that after 5 weeks, the group with TRF had the steadier heartbeat. Stable heartbeat can help maintain fat metabolism by adjusting the tolerance of glucose and adjusting blood pressure. Therefore, TRF helps weight loss due to its effect on the heartbeat and metabolism.

However, does this eating pattern mean we only need to consider the time sprints of food consumption without thinking about the frequency or time of food taken? The answer is no. If we do not stick to the same eating schedule every day, our body clock will be in a mess. This will cause unstable heartbeat and harm our immune system. In general, the recommended frequency of food intake should be three times a day. A research on female participants with different meal frequency supports this by analyzing the level of energy intake and expenditure.

Does this sound great? We can easily lose weight by limiting our meal time while eating the same things! Try to eat within 12 hours every day and don’t eat the midnight snack. Let’s see how easy and comfortable it is to live a healthy life!

by Qingyue Wang

Shrooms That Trip Together, Stay Together

I’m sure that many of you have heard of magic mushrooms, maybe you’ve even had first-hand experience with them, but where exactly does their name originate from, and why are there so many different kinds?

Psilocybe Cubensis (magic mushroom); photo courtesy of Flickr user Dick Culbert

Basically, magic mushrooms are hallucinogens. They are substances that cause alterations to your perception, your thoughts, and even to your feelings. Essentially, they cause you to “trip,” or “trip out,” because it’s almost as if they are taking you on a mind-altering journey.

The substance behind all of these fascinating effects is a naturally occurring drug known as psilocybin, and it is produced in more than 100 different species of mushrooms. When psilocybin is ingested, it is converted into psilocin, and this is the element that actually causes the hallucinogenic effects characteristic of most magic mushrooms.

For those of you still interested in the psychedelic effects of psilocybin, here is an interesting video of psychopharmacologist Roland Griffiths’ knowledge on this drug and how it may even prove to be beneficial to the terminally ill.

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The real question now is, why is this specific chemical present in so many different species of mushrooms? Well, a few scientists shared that same inquiry and this led to a study that was published in the journal Evolution Letters. This study has suggested that the production of psilocybin is primarily used as a defense mechanism against the overconsumption of the mushroom population by insects. A common side effect of psilocybin is the suppression of appetite, therefore, by causing these insects to “trip,” the bugs become less hungry and are less likely to consume more of the mushrooms.

However, this isn’t even the most interesting part. The study actually found that the genes that cause the production of psilocybin were very similar amongst distant species of mushrooms, even more so than some genes shared between members of the same species. According to the researchers, this illustrates that these genes are not inherited from a common ancestor, but are actually transferred between different species of mushrooms. This phenomenon is known as Horizontal Gene Transfer (HGT).

In essence, the genes are passed from species to species during HGT and if the gene proves to be useful, this process will continue until as many species as possible can benefit from them. Hence, the presence of psilocybin in over 100 different species of mushrooms. HGT is thought to be rare in complex living things and much more common in single-celled organisms like bacteria, making this phenomenon even more incredible.

A very simplified version of HGT and the passing of DNA from one cell to another of a different species; photo courtesy of Gregorius Pilosus from Wikimedia Commons

In a way, these mushrooms have worked together to form a solution to a problem that their individual genetic codes could not deal with alone. Now, the presence of these psilocybin-producing genes has become very widespread and has produced a huge variety of magic mushrooms. So, the next time you’re working in a team and you hear your group members stuck in a disagreement, let them know that if mushrooms can work together, so can they, and then maybe you’ll all be able to produce a little magic too.

By Silvana Jakupovic

A Glass a Day Keeps the Doctor Away!

At the end of a draining week, there is nothing more satisfying than having a long awaited glass of red wine. This may seem like a guilty pleasure, but what if your favourite weekend beverage actually has proven health benefits?

Source: Flickr

History has shown that red wine has been in production for over 6,000 years, and has been used primarily for religious purposes since its origin. However, red wine has been proven to be advantageous for one’s health.

The term wine describes an extensive class of alcoholic beverages, which are the result of grape fermentation. Although wine is a fruit product produced from grapes, the process of fermentation allows it to transform from regular grape juice, into the beverage that we all know as wine!

Ethanol is the alcoholic component in wine, and it has been proven that moderate ethanol consumption can lead to a longer lifespan. A study in Eastern France was conducted, and moderate red wine intake, which was defined as 2-5 glasses per day, was shown to have a 24%-31% reduction in mortality. Now, how exactly does red wine make you live longer?

What makes red wine so unique is the presence of secondary metabolites in grapes, which are called polyphenols. Secondary metabolites are organic molecules that are not directly involved in plant development. Rather, they indirectly aid in defense mechanisms, and keep plants safe.

The skin and seeds of grapes are the source of these polyphenols, and are essential components in the red wine making process. During fermentation of red wine, the skin and seeds are left on, thus allowing humans directly consume the polyphenols. In contrast, before being fermented, white wines are pressed off of the seeds and skins, which also explains why red wine has greater benefits when compared to white wine.

Polyphenols have vital antioxidant properties, which help to lower the overall risk of chronic diseases. They protect our body’s cells from damage, thus helping to lower the possibility of heart conditions, diabetes, and even cancer. Specifically, there is strong evidence that mortality caused by certain types of heart disease is decreased when red wine is consumed. For example, red wine can prevent build-up of fats and other substances in the arteries, ultimately reducing the risk of heart disease.

Source: Flickr

Now it is important to remember that this is all in moderation, and doctors recommend 5 ounces, or 1-2 glasses of red wine a day. With that being said, excess consumption of red wine, and similarly other alcoholic beverages, will not have the same effects, and can even lead to higher mortality. So remember, red wine may in fact have health benefits, but it is only a glass a day that will ultimately keep the doctor away.

Bottoms up!

By Alexis Llewellyn

 

The Role of Vitamin D and the Deficiency of Vitamin D

Health issues are one of major concerns of us in present days. As our lives become urbanized and modernized, we take less care of our body. Subsequently, our nutrition balances are getting worse. Unfortunately, it is undeniable fact.

One of crucially important nutrition that we are usually missing these days is Vitamin D. Many of us may have heard about vitamin D at least once.

But, it is just without knowledge of its important role in our body when it is deficient.

Vitamin D, in simple description, is a key nutrition that regulates our feelings and health (preventing depression and strengthens bones). Therefore, it causes several problems without sufficient amount of vitamin D intake.

Vitamin D is synthesized in our cell tissues under the skin with exposure of sunlight, specifically ultraviolet rays:

  • In human, when 7-dehydrocholestrelol in our skin is exposed to sunlight, it is converted into cholecalciferol which is vitamin D3.
  • In plants, when sterol meets sunlight, it is converted into calciferol which is known as vitamin D2; regulates calcium and phosphorus in our body.

Source: wordpress vitaminsaandd

We are only able to treat vitamin D in form of D2 and D3 in our body and they both work the same thing during the metabolic process.

Vitamin D is easily absorbed through the skin into our body within the wavelength of 290 nm to 315 nm. People who spend more than 20 minutes a day outside between 10 am to 2 pm would have no worries of vitamin D deficiency.

However, due to the location of Canada (cloud-covered sunlight during winter in the norther hemisphere region) and long rainy seasons, we are not freely able to enjoy the sunlight well to absorb the enough amount of vitamin D.

So, vitamin D deficiency is very common to people in Canada during the winter season since we have much less exposure to sunlight.

source: nutritionaction

As a result, vitamin D deficiency may causes several serious problems:

1) Weaken the immune system

Vitamin D enhances T-cell; cells that destroy microbes causing diseases. In case of vitamin D deficiency, T-cell may be weakened.

2) Diabetes

Risk of type-2 diabetes increases by up to 80 % – Vitamin D helps with insulin (hormone that regulates blood sugar level) secretion and conversion to glucose (a type of sugar from food we eat) energy. Low levels increase insulin resistance and damage glucose metabolism

3) Cardiovascular diseases (hear and blood vessel diseases)

Vitamin D inhibits renin which is a hormone increases the blood pressure of the systolic period. Vitamin D deficiency increases risk of several cardiovascular diseases, including hypertension (high blood pressure), heart attacks, and heart failure.

4) Depression

Vitamin D deficiency causes low serotonin levels and high cortisol hormone. Cortisol is stress hormone and serotonin is brain hormone that regulates happiness. The level of serotonin is increased when the body is exposed to sunlight.

source: department of nutrition, Harvard school of Public Health

 

To prevent vitamin D deficiency, it is best to expose oneself to sunlight 15~20 minutes a day without sunscreen. When it is not possible to spend time under the sun, however, intake of vitamin D with foods are another good option.

 

source: asianetindia

 

Sources of vitamin D from foods:

  • salmon&tuna
  • whole grains
  • egg yolk
  • mushroom
  • milk
  • cheese

source: BC Medical Journal

 

Even we intake vitamin D with foods, the content is too small for suggested daily dose. Therefore, the intake of vitamin D supplements are considered as the second-best option. However, supplements may cause the overdose problem so that it is crucial to follow the recommended dosage.

 

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Effect of Sleep Deprivation on Health

Recently, there has been increasing interest in the effect of sleep time on the life quality. Some researches show that sleep deprivation costs the UK economy £40 billion a year, due to the reduced productivity and health. And by the recent research in 2015, it indicate that the sleep-deprived human brain has problem in both focusing and remembering. These evidences definitely show us that we need high-quality adequate sleep. So how to make our sleep more efficient had become a mystery that beset scientists for the past 20 years.

Because while the light bulb and advanced technology brought about a world of 24 hours work and productivity. It has come at a cost of our naturally biological clock and our brain’s need for sleep.The evidence shows that nurses who work more than 12.5 hours are significantly decreased vigilance, suffering an occupational injury, or making a medical error. Comparing with the normal physician, the 24-hr on-call physician has twice as many working faults during the night shift and trigger 36% more serious medical errors.

Effects of Sleep Deprivation

Last year, the scientists in Italian concluded that sleep deprivation will cause some cells to consume other parts of our brain’s synapses such as astrocytes. They are kind of star-shaped cells that able to remove worn-out cells. The result concludes that the astrocytes went into overdrive in sleep-deprived mice will cause more broken of the brain’s connections, and may lead to Alzheimer’s disease. Also, the research by Surrey University concluded that over 700 of the body’s genes, including those that govern the immune system, are altered when someone has sleep less than 6 hours.

Synapse

As a result, the weight of evidence suggests that sleep deprivation highly increase fatigue and threaten our safety. For the long-term perspective, it really has a significant effect on our health and well-being. Thus, I hope we can all have high-quality adequate sleep every day.

Having a large sweet tooth may lead to Alzheimer’s

Source: Pixabay

A high-sugar diet has developed a negative connotation over the past few decades. This can be attributed to the countless studies showing the adverse effects sugar can have on the body physically.

To further fuel the negativity associated with sugar, a recent study has found that high blood sugar levels are linked to negative cognitive effects in their participants.

The study, published in Diabetologia, observed 5,189 participants over a period of about 8 years. Their results concluded that all participants demonstrated a cognitive decline over this time span. Interestingly, however, those patients with observed high sugar levels demonstrated a much faster rate of cognitive decline than those with healthy sugar levels.

The study above exposes a clear relation between high sugar levels and cognitive decline, but this revelation is far from ground-breaking. Some scientists have long been referring to Alzheimer’s as ‘type-3 diabetes’. This name came about due to the fact that individuals with diabetes have a higher chance of developing Alzheimer’s.

For me, this is a scary prospect. As a woman with a genetic disposition to diabetes and a sweet tooth propelled by the overwhelming amount of sugar in the South Asian diet, I am a clear candidate for developing Alzheimer’s.

How exactly does this development occur, though?

Dr. Eric Berg, from his YouTube channel Dr. Eric Berg DC, explains the mechanism behind the phenomenon in the video below.

In the video, Dr. Berg states that those with high sugar levels develop insulin-resistance in the body, which results in low sugar metabolism. This ‘starves’ the brain and creates significant memory failures, leading to Alzheimer’s. In the end, he mentions cutting out sugar from our diets entirely, to help prevent the development of the disease.

Cutting sugar out of our diets is no simple thing, however. The Keto Diet Podcast touches on some societal barriers when it comes to switching over into diets that involve less sugar. In her interview with Amy Berger regarding her book, The Alzheimer’s Antidote, Leanne Vogel mentions that even after a run fundraising for Alzheimer’s the meals offered included many dishes with carbohydrates, with few alternative options. She also mentions the candies being ever-present in her grandfather’s care home, despite him having developed the disease already.

Listen to the full podcast by clicking below.

Excess sugar leading to Alzheimer’s disease is a link that may now be considered a fact due to the overwhelming amount of evidence. In order to ensure a future of all round health, we should take care of avoiding extra sugar in our diet. Personally, I plan to replace the chocolate bar with an apple, skip the mid-day Frappuccino, and have the medicine go down without a spoonful of sugar.

-Pravnit Kooner