Category Archives: Science in the News

Global domination of teleost fish

With humans surviving on every continent, it is easy to believe that we are the dominant species on earth. However, humans live on land which takes up only 29% of the earth’s surface. The other 71% of earth is covered by water. Here a different class of organisms dominate, the teleost fish.

What are teleost?

Teleost fish are the largest group of ray-finned fishes with over 26, 000 species. Approximately 96% of fish on the planet are considered teleost.

Teleost fish are the largest infraclass of Actinopterygii, the ray-finned fish. Image taken from Wikimedia.

Teleost fish are often identified by their:

  • Symmetric forked tail structure
  • Moveable upper jaw
  • Swim bladder
  • Unique eye structure

Teleost fish include many well known species such as rainbow trout, piranhas, and clownfish. Some examples of non-teleost fish include the sharks, rays,  sturgeons, and lampreys.

Sturgeon is an example of a non-teleost fish. Image taken by Melissa Shavlik.

Current reserach with teleost

How did these teleost fish win the evolutionary race against other species and dominate today’s oceans? Dr. Brauner, a researcher in the Department of Zoology at UBC, attempted to solve this mystery through his research article, “A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina.”  which was published this August. In this article, Dr. Brauner explains how the presence of a unique blood vessel structure (choroid rete mirabile), behind the eye is lined with a type of protein (vacuolar-type H+-ATPase) that is part of an efficient chemical mechanism in the eye. These factors allow teleost to be more sensitive to light over their competition.

The eyes of the teleost fish have fewer visible blood vessels in the eye compared to other species. Image created by Chris Betcher.

While the cause of teleost dominance has yet to be proven, Dr. Brauner hopes to find answers to this in the future as well as using this research to help better understand how the acidification of the ocean could affect teleost fish. He also noted that oxygen delivery is a hot topic in the cancer research field and that this mechanism could help us better understand and treat cancer in the future.

Fish Physiology series co-editors Dr. Colin Brauner and Dr. Anthony Farrell. Image from UBC Library.

In the following video, Dr. Brauner elaborates in detail on the eye mechanisms of teleost fish along with explanations on the sheer efficiency inside the teleost fish eyes compared to human eyes. 

How the teleost changed over time

The HOOKED podcast segment features a discussion on the significance of teleost dominance, along with additional evolutionary mechanisms that were developed by the teleost fish species. 

Mysteries of the teleost that have yet to be unlocked.

While the true factors which caused the teleost class of fish to become evolutionary dominant remains a mystery, researchers like Dr. Brauner are using various mechanisms to help us try and find these answers. This could ultimately lead to the uncovering of new truths about evolution, the history of fish, how these fish will be affected by climate change, as well as helping us better understand the species which we share a planet with. After all how can humanity plan for the future without understanding those we share the planet with?

– A collaboration by Michelle Huynh, JD Villareal, Gordon Wu, & Yoshinao Matsubara

Additional sources: The Hooked Podcast uses bubble sound effects and congo sound effects from soundbible.com.

AI in Medical Care: Google’s Patent

Google is about making a revolution in the medical world. They have obtained a patent to process patient diagnostic data using artificial intelligence (AI). This will align the contents of clinical notes written in different styles to the same format. Organizing clinical notes makes it easier for medical institutions to share patients’ information on Electronic Health Records (EHR). In addition to preventing misdiagnosis due to oversight of treatment plans and medical history, the prediction of diseases and illnesses can be done using data analysis.

Image: Runner 1928/Wikimedia

EHR

EHR has been generalized among US medical institutions to compile and store the patients’ data. A most important part of  EHR data is a clinical note that provides all the information from a patient’s medical history to diagnosis and treatment planning.

However, the way medical professionals write a clinical note is different; some notes are handwritten whereas some of them are voice memos.  Unorganized clinical notes can lead to information oversights and data duplication, which can affect clinical outcomes.

The patent that Google obtained uses a neural network to edit, to systematize, and to interpret unorganized clinical notes so that doctors can make accurate diagnoses.

Image: Own Work/Wikimedia

How the System Works

The patent explains the system called “future health prediction system” that uses neural networks to capture patient data from clinical notes and to interpret the data. It then shows the patient’s diagnosis and findings on future health risks.

One of the abilities of the system is calculating the risk of a certain disease. The system extracts the medical history from the patient’s EHR and converts the data to a variable that the neural network can recognize and process. If the system finds, for example, a disease A in his/her family’s medical history, then it points out that the patient is at a higher risk of developing this disease.

This system will also be useful for preventive care. For example, if a family doctor introduces this system to show patients risk factors for various illnesses based on medical records, it will be able to predict the possibility of certain diseases such as heart attack and stroke in the future. This will allow them to make more preventive decisions, such as recommending a low-salt diet or requesting the use of certain medications, which may reduce the patient’s risk of developing the disease in the future.

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Source: Google

Why is this important?

Doctors who do not have a complete record of the patient may make an incorrect diagnosis, which could result in an inadequate treatment plan for the patient.  The system helps doctors diagnose a patient’s specific illness by simplifying and supplementing the diagnostic process and improving the accuracy of the diagnosis.

These patents haven’t been put to practical use yet, but there is no doubt that they will make a big difference in medical care soon.

ーShunya Sunami

Fighting Climate Change by Capturing Excess CO2.

Climate change is becoming a serious issue as temperatures continue to rise due to increasing global greenhouse emissions. Greenhouse gases such as CO2 trap reflecting sunlight and radiation that would normally escape the atmosphere of Earth and this trapped heat then leads to warmer temperatures. Over the past 150 years, Carbon dioxide(CO2) emissions around the world have increased mainly due to human involvement through the burning of fossil fuels and industrial processes. The figure below outlines the percentages of various greenhouse gas emissions and their sources.

Credit: IPCC(2014)

Due to these rising emissions, there are many researchers and technology companies around the world that are looking at ways to reduce the amount of atmospheric CO2 and mitigate climate change before it is too late. In the past few years, many new technologies and techniques to capture excess carbon have emerged. Some of these main ones include Bioenergy with Carbon Capture and Storage(BECCS or bio-CCS) and Direct Air Capture(DAC). Although the ultimate goal of both methods is to reduce carbon emissions, BECCS focuses on capturing CO2 released through combustion in industrial facilities while DAC aims to directly capture excess CO2 from the atmosphere. From these two methods, companies such as Carbon Engineering who are employing DAC have gained more traction as they have landed large investors such as Bill Gates and Chevron.

A study posted in 2018 outlined the process and cost of Direct Air Capture(DAC). Through this research, a Canadian company called Carbon Engineering based in Squamish, BC has tested the Direct Air Capture technology and hopes to make various large scale carbon storage plants over the next few years. Another company called Climeworks based in Switzerland is using similar methods to capture carbon from the atmosphere. Carbon Engineering has a plan to use the carbon from the atmosphere in 2 different ways which are reusing the stored carbon as a source of fuel and the second being storing solid carbon underground. According to the company, one large scale plant can store as much carbon as 40 million trees. They believe it is an efficient way to reducing carbon emissions and as they continue to get more funding they become closer and closer to their goal.

This video below explains the Direct Air Capture(DAC) method of removing CO2 and also outlines the various ongoing and future projects to mitigate climate change.

-Sandeep Singh

Why Does Good Music Give Us The Chills? How Music Can Affect Your Mind

People enjoying music

People enjoying music. Image: OmarMedinaFilms on pixabay.com

For as long as it has existed in the world, music has been pleasing generations of people who adore the art form.  But, even though many of us listen to music for pleasure, how exactly does music give our brains that pleasure? Until recently, no studies had definitive answers for that question. But, a recent breakthrough study from a group of French neuroscience researchers may have an answer for that question of how music makes us feel good.

What The Study Found

This study differs from previous papers on the same topic by introducing a method of collecting information not used before in this type of research: electroencephalograms (EEGs). EEGs are a collection of sensors attached to a person that is used to monitor a person’s specific brain activity. Below is a short video explaining how the technology works. The study used EEG technology to monitor 18 participants who were monitored for a baseline reading before being given headphones with preselected music that the participant had chosen based on what gives them chills.

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Past research on the topic had already illuminated the possibility of good music affecting human reward centers in the brain, similar to how eating good food or having sex activates human reward centers. But this study was the first to actually monitor some of these reward centers activating in the brain in response to music.

When participants listened to a song that gave them the chills, the scientists conducting the study found that there was a significant increase in theta-waves in certain parts of the brain associated with emotional processing. These patterns of theta-waves, which are normal oscillating brain activity, indicate that the brain starts emotionally processing music once it starts to recognize it. In addition to these theta-waves, the study also states that dopamine (a hormone that is associated with pleasurable experiences) is released in the brain in response to hearing music. These two responses combine in the brain to produce, among other things, the effect of having chills.

Diagram of what an EEG and EEG reading looks like. Image credits: springer.com article “Electroencephalogram (EEG) and Its Background”

So why do our brains do this?

While this study has greatly illuminated the processes that occur in the brain in response to music, there is still not much that is known as to why these processes occur in the first place.

Some of the scientists who conducted this study have noted how interesting it is that music activates our reward centers yet it provides no visible evolutionary advantage that could have led to us evolving this response through natural selection.

Many scientists have theorized what purpose music could have played in our ancestral lives, or if it even played any role at all. It is entirely possible that music was created to exploit existing human reward systems similar to how drugs and junk-food exploit evolved-human reward systems from our ancestral lives. But until more research is done on this topic, we cannot conclude why music gives us the chills.

– Ryan Reiss

Scientists have Discovered a Cure for Cancer

You have probably seen many articles with similar titles to this one throughout your lifetime, however as you probably know we do not have a cure for cancer. So what were these cures and why is there such a large disconnect between published research and subsequent mainstream articles published on the topic. I recently came across an article from the BBC titled Immune discovery ‘may treat all cancer’ while the title is not directly claiming that a cure was found, it does make the reader think that we might have a treatment which could help cure all types of cancers. When reading through the article the author talks about how scientists found a type of immune cell which can be modified so that it can detect and kill multiple types of cancer cells while leaving normal cells intact. If we look at the original research article we will find that the researchers genetically modified human immune cells so that they would have an extra receptor that could recognize and kill multiple types of human cancer cells while not affecting non-cancer cells. The video below gives an overview on how scientists are trying to use the immune system to fight cancer, note that the study above uses CAR-T therapy (video taken with Creative Common License).

From this we can see that the author of the BBC article is not lying to their readers, and the author goes even further to state at the end of this article that “the research has been tested only in animals and on cells in the laboratory, and more safety checks would be needed before human trials could start.” This statement is normally the root cause for disconnect between the scientific publications and mainstream articles for two main reasons. First not all mainstream articles will include this information leading the reader to assume that treatment is almost ready or it will be included at the end of the article so that readers who do not complete the article will have a false understanding of how close the treatment is to being used in humans. The second reason I believe there is a disconnect is due to the level of knowledge the general public has about cancer research compared to someone who has experience in the field. Someone with experience will know that cancer research in petri dishes and animal subjects differs heavily for cancer research in humans. For example the mice used in this study had been modified in such a way so that none of the mouse’s original immune system was functional and only the modified human immune cell was functional. Cancer research also takes a long time so if this treatment was approved for human testing today, it would take around 10-15 years before it could be approved as an actual treatment. From this I hope the next time you see a “cure for cancer,” you remember the comic below and check to see how far along in the research stages this treatment is.

This image was taken from: xkcd with Creative Commons License

 

Study Suggests Video Games Can Improve Your Mental Health

A person playing on a Nintendo Switch. Image: Mister Mister / Pexels

With people staying indoors due to the COVID-19 pandemic, many will socially connect through video games. A new timely study by Oxford University, using actual gameplay data for the first time, suggests playing video games can be beneficial for your mental health.

The study, which focused on popular games such as Nintendo’s Animal Crossing: New Horizons, as well as Electronic Art’s Plants vs Zombies: Battle for Neighborville, found that experiences of social connection with others through play may contribute to people’s wellbeing.  In other words, those who enjoyed playing were more likely to report positive wellbeing.

Crucially, the study is the first of its kind. Rather than asking players how much they play, it uses industry data on actual playtime. This let the Oxford University study team link psychological questionnaires along with true records of time spent playing games. This is important since in the past, studies tended to focus on self-reported time playing, which has been found by the study to be weakly correlated with reality.

“Without objective data from games companies, those proposing advice to parents or policymakers have done so without the benefit of a robust evidence base,” said Professor Andrew Przybylski, Director of Research at the Oxford Internet Institute, University of Oxford, and lead-author of the study.

Przybylski said, “this is about bringing games into the fold of psychology research that’s not a dumpster fire,” allowing us to explain and understand video games a leisure activity.

People smiling while playing video games. Image: cotton bro / Pexels

The researchers were surprised by how little data gaming companies actually had about their players — but also how little hard data had been used by previous studies for the potential harms and benefits of gaming.

The study explored the link between objective game time and well-being, examining the association between directly measured behaviour and subjective mental health. It also explored the roles of player experiences, specifically how feelings of autonomy, relatedness, competence, enjoyment and feeling pressured to play related to well-being.

In the study, 3,274 players were asked to complete a survey designed by the researchers to measure well-being, self-reported play, and motivational experiences during play. The survey findings were combined with objective behavioural data for the survey participants, collected by the video game companies.

Looking Ahead

The researchers hope the study will introduce a higher standard of evidence to discussions about the concept of video game addiction, or digital harms in general.

“You have really respected, important bodies, like the World Health Organization and the NHS, allocating attention and resources to something that there’s literally no good data on. And it’s shocking to me, the reputational risk that everyone’s taking, given the stakes. For them to turn around and be like, ‘hey, this thing that 95% of teenagers do? Yeah, that’s addictive, no, we don’t have any data,’ that makes no sense,” Przybylski said.

While the findings indicate an increase in wellbeing through playing video games, this may not be the case if research continues for more games where behavior deemed as toxic may be found.

 

– Amrit Jagpal

The Future of Antarctica

In September 2019, the Amery Ice Shelf in Antarctica produced its biggest iceberg, which beat the record 50 years ago. The massive iceberg named D-28  covers an area of 1,636 sq km, which is slightly more than half of the Metro Vancouver area. It is about 210 m thick and contains 315 billion-tonne of ice.

Iceberg D-28 breaks away from the Amery Ice Shelf. Credit: ESA

 The cause of iceberg D-28 calving?

As a matter of fact, global warming, caused by greenhouse-gasses emission, has contributed to ice melting around the world. It is interesting to note that the calving of D-28 was a part of the normal cycle of ice shelves.

Firstly, glacier gradually moves toward the ocean by its own weight. As the glacier flow, the friction with the bedrock and surface melting thinning the ice sheets and form ice shelves, which are the arm of the ice sheet. Moreover, the warm circumpolar deep water flows in and melts the ice under the ice shelf that weakening its strength. Thus, the plane of ice starts splitting and shedding into icebergs.

Formation of icebergs. Credit: Calvin Pan

Climatic impacts of the iceberg

Melting icebergs influence both global sea levels and ocean salinity. If iceberg D-28 completely melted, researchers projected that sea volume would increase by 2.6 % compared to the volume of saltwater that was displaced. Annually, the global sea level is rising by about 3 mm, whereas the melting of D-28 only accounts for 0.049 mm of increase per year. As such, an individual iceberg would not dramatically raise the sea level. In considering the ocean salinity, indeed, the melted ice would dilute the salt concentration in the ocean and decline its salinity. This process usually occurs at lower latitudes when the iceberg melts. Nevertheless, at higher latitudes (eg, near where the iceberg breaks off), seawater is frozen by nearby icebergs, and its freezing process increases the salinity. The stabilizing influence on ocean salinity promotes the convection and circulation of oceanic currents.

Will climate change alter the Antarctic landscape?

Yes, climate change will accelerate the loss of Antarctic glaciers due to various reasons. For example, warmer sea, higher air temperatures, and higher sea levels fasten the natural cycle of ice shelves. Watch this short video made by Vox to understand the association between glaciers loss and climate change using the example of Thwaites Glacier, as well as possible consequences.

A study has proposed that reducing greenhouse-gas emissions could possibly mitigate the rate of change in Antarctica. Losing antarctic ice will not only raise the sea level but also threaten wildlife and food security because of more frequent extreme weather. Before dealing with an irreversible change in Antarctica, we must start thinking of how we can save the Antarctic ecosystem.

-Calvin Pan