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Global domination of teleost fish

With humans surviving on every continent, it is easy to believe that we are the dominant species on earth. However, humans live on land which takes up only 29% of the earth’s surface. The other 71% of earth is covered by water. Here a different class of organisms dominate, the teleost fish.

What are teleost?

Teleost fish are the largest group of ray-finned fishes with over 26, 000 species. Approximately 96% of fish on the planet are considered teleost.

Teleost fish are the largest infraclass of Actinopterygii, the ray-finned fish. Image taken from Wikimedia.

Teleost fish are often identified by their:

  • Symmetric forked tail structure
  • Moveable upper jaw
  • Swim bladder
  • Unique eye structure

Teleost fish include many well known species such as rainbow trout, piranhas, and clownfish. Some examples of non-teleost fish include the sharks, rays,  sturgeons, and lampreys.

Sturgeon is an example of a non-teleost fish. Image taken by Melissa Shavlik.

Current reserach with teleost

How did these teleost fish win the evolutionary race against other species and dominate today’s oceans? Dr. Brauner, a researcher in the Department of Zoology at UBC, attempted to solve this mystery through his research article, “A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina.”  which was published this August. In this article, Dr. Brauner explains how the presence of a unique blood vessel structure (choroid rete mirabile), behind the eye is lined with a type of protein (vacuolar-type H+-ATPase) that is part of an efficient chemical mechanism in the eye. These factors allow teleost to be more sensitive to light over their competition.

The eyes of the teleost fish have fewer visible blood vessels in the eye compared to other species. Image created by Chris Betcher.

While the cause of teleost dominance has yet to be proven, Dr. Brauner hopes to find answers to this in the future as well as using this research to help better understand how the acidification of the ocean could affect teleost fish. He also noted that oxygen delivery is a hot topic in the cancer research field and that this mechanism could help us better understand and treat cancer in the future.

Fish Physiology series co-editors Dr. Colin Brauner and Dr. Anthony Farrell. Image from UBC Library.

In the following video, Dr. Brauner elaborates in detail on the eye mechanisms of teleost fish along with explanations on the sheer efficiency inside the teleost fish eyes compared to human eyes. 

How the teleost changed over time

The HOOKED podcast segment features a discussion on the significance of teleost dominance, along with additional evolutionary mechanisms that were developed by the teleost fish species. 

Mysteries of the teleost that have yet to be unlocked.

While the true factors which caused the teleost class of fish to become evolutionary dominant remains a mystery, researchers like Dr. Brauner are using various mechanisms to help us try and find these answers. This could ultimately lead to the uncovering of new truths about evolution, the history of fish, how these fish will be affected by climate change, as well as helping us better understand the species which we share a planet with. After all how can humanity plan for the future without understanding those we share the planet with?

– A collaboration by Michelle Huynh, JD Villareal, Gordon Wu, & Yoshinao Matsubara

Additional sources: The Hooked Podcast uses bubble sound effects and congo sound effects from soundbible.com.

HOW CLIMATE CHANGE IS MAKING HURRICANES SCARIER

The Greatest Storm on Earth

When thinking about powerful natural events on Earth, one might think of raging tornadoes, or blizzards that can shut down cities, but the power of a hurricane is so immense, that they can release up to 10000 nuclear bombs worth of energy of the course of their lives. The power of these natural storms is so great, they are sometimes even visible to Earth even from other planets in our solar system, take the Great Red Spot of Jupiter for example. On Earth, generally hurricanes start to develop in areas of high humidity and relatively warm surface water temperatures, mixed with faint winds. This is why “hurricane season” is generally in the summer and early fall in the northern hemisphere. Hurricanes are devastating to the terrain and any infrastructure caught in their path, and as such is an important issue for people who live in areas known that are likely for hurricanes to hit. The video below from National Geographic goes over some of the specifics when it comes to how a hurricane is made, for further info on the topic.

Hurricane Decay

Eventually, when hurricanes hit land they will slowly start to decay, as the moisture from warm ocean subsides, the hurricane has nothing fueling it, as hurricanes require moisture and heat to continue on. After being cut off from the ocean, the decrease in moisture level also contributes to an simultaneous decrease in the hurricanes intensity.

In the scientific literature, there are already studies looking at how climate change affects hurricanes, and particularly how climate change affects the intensification of some tropical cyclones, but until recently, the question of how the intensity decay was being affected by climate change remained unanswered.

A hurricane at the start of hurricane season / Taken from Flickr user militarymark2007

The Findings

Recently, researchers Lin Li and Pinaki Chakraborty of the Okinawa Institute of Science and Technology have determined through an analysis of historical climate data, alongside computer simulations, that climate change is contributing to the slower decay of hurricanes after landfall. By checking through the hurricane intensity data gathered over the last 50 years in the North Atlantic, they found that “hurricane decay has slowed… in direct proportion to a… rise in the sea surface temperature”. Looking back to the late 1960’s, an average hurricane then would lose around three quarters of it’s intensity a day after it made landfall, whereas an average hurricane now would only lose around half of it’s intensity a day after making landfall. By using computer simulations, they determined that the higher sea surface temperatures are causing the slower decay rate, as the moisture level is now also higher, alongside the amount of heat to fuel the hurricanes ‘engine’, leading to a longer and stronger hurricane after landfall.

Looking Ahead

As we look forward, strategies to mitigate climate change and reduce global warming might become top priorities in a world with an ever increasing climate, and unfortunately now, with even stronger hurricanes.

Hurricane as seen from the ISS by Astronaut Ed Lu. By Image courtesy of Mike Trenchard, Earth Sciences & Image Analysis Laboratory, NASA Johnson Space Center. – http://earthobservatory.nasa.gov/NaturalHazards/view.php?id=12140, Public Domain, https://commons.wikimedia.org/w/index.php?curid=625449

 

– Mehdi Mesbahnejad

Does an Obesity Gene Exist?

Genes play a big role in determining how a person looks including our eye color, hair color, and height, but can your genes also determine your waistline? As of now, 61% of Canadians are overweight or obese and that number is even higher in America, with 66% of its citizens overweight or obese.  While these numbers can be attributed to a more sedentary lifestyle and poor diet, genetics has been shown to be a factor. A study in 1986 found that adopted children’s BMI more closely matched their biological parents than adoptive parents. While environmental factors play a huge role in a person’s weight, the importance of genetics cannot be understated.

One of the first genes to be linked to obesity was the melanocortin-4-receptor gene (MC4R). In 1998 a study found that mutations in MC4R would lead to early-onset obesity in children. However, this mutation is extremely rare, affecting less than 5% of those suffering from obesity leading researchers to search for more common genetic variations. Starting in 2002 scientists began to perform genome-wide association studies (GWAS). Instead of looking at genomes of a few hundred people, scientists could now look at entire DNA sequences of hundreds of thousands of people in order to find links between certain genes and illness.  A GWAS in 2007 led to the discovery that variations in the fat mass and obesity (FTO) gene were associated with higher BMI’s. These variations were much more common with 43% of the population carrying this “risky” allele of the FTO gene.  The study found that individuals with certain variations of this gene were 1.67 times as likely to be obese. Despite this, the FTO gene itself only raised BMI .4 kg/m^2 an amount much too small to lead to the increase in BMI observed (3 kg/M^2). This is why the majority of obesity in the population is caused by many genes, not just one. Since 2006 GWAS has led to the discovery of more than 50 genes associated with obesity.

The discovery of these genes not only can tell us who is predisposed to becoming obese, but who is also more likely to suffer from metabolic diseases associated with obesity like heart disease, stroke, and type 2 diabetes. This video from the University of Michigan explains some of the surprises that came from studying genes related to obesity and how we can use this information to benefit people.

YouTube Preview Image

 

 

However, just discovering these genes isn’t enough. In order to treat these variations, we have to better understand the mechanism of these genes. Recent studies have revealed that variations of the FTO can cause alterations in satiety that people feel, but the exact mechanism of these effects are still largely unknown. For now, proper exercise and nutrition can counter the effects of most of these “fat” genes. In the future, people may be able to find the best way to prevent weight gain based on their genetic makeup. Only time will tell if future discoveries can reverse this obesity epidemic.

 

By Dylan Chambers

From Earth to Beyond: Colonizing Mars

Past and Present

Humans have always been a curious species and have spent lots of time trying to figure out the mysteries of the universe. From launching thousands of satellites to space to landing a man on the moon, space exploration has continuously advanced through time. In the past, space agencies from around the world have completed various missions to space to explore different stars and planets such as the Moon and Mars. Humans continue to explore as they did in the past and now once again there is an increasing interest in space exploration.

In the past few years, there has been an increasing interest in searching for possible planets for humans to survive on. This has led to increased funding for research on planets like Mars. Mars is one of Earth’s closest neighbouring planets. Mars was first discovered in 1609, by Galileo Galilei who first saw it through a telescope. Since then, many satellites, probes and rovers have been sent to Mars to examine its surface and look for water and other signs that can help sustain life. Mars falls within the habitable zone in our solar system known as the Goldilocks zone. The Goldilocks zone is a zone around a star which is at a distance with a suitable temperature allowing liquid water to exist. The zone is shown in the image below. Research has shown signs of water on Mars but due to its thin atmosphere, much of it has frozen or evaporated. There are methods which are possible to artificially warm-up Mars according to space companies such as SpaceX. Mars also has 38% gravity of Earth which researchers suggest humans can adapt to. Moreover, a day on Mars is about 24 hrs and 37 min which is very similar to a day on Earth. While many factors determine the ability of a planet to support life, these factors have led scientists to consider Mars as a possible candidate for supporting human life.

Credit: Cornell University
Found on NASA astrobiology website

 

The Future

Due to the amount of radiation on Mars surface humans cannot walk around unprotected. The thin atmosphere on Mars would have to be shielded from solar winds and life on Mars would be mostly spent living in capsules. Many researchers and space organizations believe that Mars can be transformed into a fully habitable planet like Earth over time. Many organizations and companies like NASA and SpaceX are expanding Mars research and looking for ways to fix these problems.  SpaceX has a plan to send its first crew to Mars in the year 2024 while NASA has a more long term plan which includes sending crews to the Moon first as a preparation for larger missions to Mars. The video below shows how life on Mars would initially look like. As more research is done, humans will become one step closer to understanding ways of colonizing other planets such as Mars.

 

– Sandeep Singh

Mitigating Climate Change: Carbon Capture (Revised)

Have you heard concerns regarding climate change in the past few years? I think almost everyone has, which goes to show how serious this global issue really is.  One of the main causes of climate change is the release of excess carbon dioxide into the atmosphere, due to the burning of fossil fuels. If we could somehow reduce these greenhouse gas emissions, climate change would pose less of a threat to humanity. 

A solution to climate change

One solution that scientists have proposed in order to reduce the amount of atmospheric carbon dioxide is to capture carbon dioxide in the air and use the captured carbon dioxide as a source of chemical carbon for other processes. This process is known as “carbon capture and utilization” (CCU). Although the potential benefits of CCU are very promising, changing the carbon dioxide into a different form and using it in other chemical processes has been proven to be difficult. Although CCU has gained major traction over the past few years, it will still require a lot of time before it can be used industrially worldwide. Scientists are currently in the process of trying to find the least costly, and most efficient means of capturing carbon emissions to reduce climate change. 

Image: Carbon Capture and Utilization Process                          Source: Wikimedia Commons                                                           Relevance: Shows path of CO2 in this process

 

Carbon capture methods

One of the carbon capturing methods that has been showing promise in recent scientific studies, is the adsorption of carbon dioxide through the use of solid sorbents. Adsorption is the adhesion or the clinging of gas molecules onto a surface. In this case, the carbon dioxide molecules will stick to the solid surface of the sorbent, which leads to successful carbon capturing. The solid sorbents used in this method can be made of “porous carbonaceous materials, zeolites, alumina, silica, (or) metal-organic frameworks.” Adsorption of carbon dioxide can be categorized into two variations; physical and chemical adsorption. In physical adsorption, the transfer of carbon dioxide into the solid sorbent occurs due to the Van der Waals interactions (attraction between neutral molecules) between the sorbent and the carbon dioxide. The issue with these physical sorbents is that they have “poor selectivity for CO2 and low CO2 adsorption capacities.” A means of improving both the carbon dioxide selectivity and the carbon dioxide adsorption capacities of these sorbents is by adding basic groups to the sorbent surface, which can strengthen its interactions with the acidic carbon dioxide. Although carbon dioxide adsorption via solid sorbents is very promising, more scientific work needs to be done to improve the adsorption capabilities of sorbents.

YouTube Preview Image                                                      Video: Carbon Capture Plant in Squamish, BC

Although CCU has gained major traction over the past few years, it will still require a lot of time before it is used industrially worldwide, and this timeline is uncertain. Moving forward, scientists must also be wary of the energy consumption of these carbon capture mechanisms, as they could use “a quarter of global energy in 2100”.

– Yoshinao Matsubara

Failure to Communicate

Introduction 

Right now communicating science to the general public is more important than ever, and we are failing. Less than 50% of Americans say they would receive a vaccine for COVID-19. This shows the eroding trust that the public has for their once highly esteemed scientist. This is the result of breakdowns in the scientific method that have led to conflicting information being shared with the public.

Mask  Wearing

Perhaps the most notable slip up was the controversy surrounding masks.  While recommended now, it was not until April 3rd, three months into the pandemic, that the CDC began recommending the general public to wear a mask. This was in direct conflict with their earlier statements that only healthcare workers needed masks.  Scientists rushed conclusions that could not be properly verified before being shared with the public. The public demanded answers from a process that can take years, in a matter of weeks. By caving in to public demand, the CDC and World Health Organization were inevitably set up for failure as the pandemic progressed and more data was collected leading to new developments. Tweets from the U.S surgeon general like this

Tweet by Surgeon General Feb 29

only serve to fuel distrust when compared with tweets he makes a few months later.

Tweet by Surgeon General June 14

 

I do not fault scientists for changing their opinion as new data became available, but I do fault (some) scientists for stating their answers with confidence when the proper research and review had not been conducted.

 

Treatment

Image: flickr

Scientists have been under enormous pressure to find treatments for COVID-19 that can reduce mortality and infection rate. This has created haste in the scientific method and has allowed some treatments to receive emergency authorization from the FDA such as remdesivir. Even these emergency authorizations are accompanied by randomized, double-blind, placebo-controlled clinical trials that assure treatments are safe. These methods for testing were not present in the study of Hydroxychloroquine that led to its eventual emergency authorization.  The original study involved only 26 patients treated with Hydroxychloroquine that were compared to 16 untreated patients at a different hospital. Later studies conducted on Hydroxychloroquine would question its effectiveness as a treatment for COVID-19 and thus the scientific process was able to correct itself and the FDA revoked the use of Hydroxychloroquine. However, the public once again lost its trust in doctors. This opened the door to rumors and conspiracy theories to dominate the public view. In a pandemic where time is everything the spread of misinformation costs lives

By allowing leniency in the scientific method, we have opened the flood gates to all types of information being thrust onto the pedestal once reserved for the conclusion from the scientific method. Your uncle’s Facebook post about the healing power of Clorox bleach carries as much weight as the cutting edge research on COVID-19. Scientists have lost credibility with the public. This is not the first time this has happened, but it may be the most damaging.

 

Dylan Chambers

Lowest Levels of PM2.5 are Still Deadly

What is PM2.5 - Pattaya Mail

Image from: Pattaya Mail

There are some things in the world that you know are bad for you, and that you can see, but air pollution is a different story. Ultrafine particulate matter, which are smaller than a strand of human hair, is known as PM 2.5. Because of its size, it can easily penetrate the natural barriers of your mucus and nostrils and directly access the bloodstream. These particulates are considered a major environmental risk and can contribute to a host of illnesses such as an increased risk of stroke, heart attacks, and both chronic and acute respiratory disease. As well, these particulates can exist as dust, fossil fuels emissions, and even indoor cooking smoke! So now you’re probably thinking, I should try to avoid and limit my exposure to PM2.5  as much as possible, but even that might not be enough.

Size comparisons for PM particles

Relative small size of PM2.5 compared to other objects.
Image from: USA EPA

 

The Environmental Protection Agency (EPA) recommends that the annual exposure to PM2.5 does not exceed 12 micrograms per meter cubed. However, a recent study showed that even stricter guidelines should be implemented. The study found that 99% of PM2.5 associated deaths occurred at PM2.5 levels below the current EPA guidelines. In the study, they compared 4.5 million veterans with annual levels of ultra-fine particulates where they lived, and the results showed that the average particulate levels were lower than 12 micrograms. So, this begs the question, are our current air pollution laws good enough to prevent the health consequences? Ziyad al-Aly, the co-author of the study says that “there’s not a whole lot a person can do other than really participate in the discussion”.

So what can you do then as an individual who cares about the wellbeing of people and the planet? Demand action by local, regional, and national level policy-makers working in sectors like transport, energy and urban planning. According to the World Health Organization (WHO), one way to reduce PM2.5 levels is by shifting to electric vehicles from diesel engines. A successful example is the Californian Diesel Risk Reduction plan, where the government implemented tighter diesel emission standards for car manufacturers and lowered PM2.5 concentrations.

It is unfortunate to learn that even the lowest levels of particulate matter can affect our health in the long-run, however it also encourages us to take action immediately. By reaching out to policy makers and becoming an active voice in the community, perhaps we can make progress towards cleaning our air.

– Michael Ge

From Earth to Beyond: Will Humans Ever Live on Another Planet and What Would Life Beyond Earth Look Like?

Past, Present and Future

Humans have always been a curious species and have spent lots of time trying to figure out the mysteries of the universe. From launching thousands of satellites to space to landing a man on the moon, space exploration has continuously advanced through time. Throughout time, space agencies from around the world have completed various missions to space to explore different stars and planets such as the Moon and Mars. Humans continue to explore as they did in the past and now with the increasing interest in space exploration, there is no doubt that one-day humans will live on another planet.

Where would we go?

In the past few years, there has been an increasing interest in searching for possible planets for humans to survive on. This has led to increased funding for research on planets like Mars. Mars is one of Earth’s closest neighbouring planets. Mars was first discovered in 1609, by Galileo Galilei who first saw it through a telescope. Since then, many satellites, probes and rovers have been sent to Mars to examine its surface and look for water and other signs that can help sustain life. Mars falls within the habitable zone in our solar system known as the Goldilocks zone. The Goldilocks zone is a zone around a star which is at a distance good enough for liquid water to exist. The zone is shown in the photo below. Research has shown signs of water on Mars but due to its thin atmosphere, much of it has frozen or evaporated. There are methods which are possible to artificially warm-up Mars according to space companies such as SpaceX. Mars also has 38% gravity of Earth which researches suggest humans can adapt to. Moreover, a day on Mars is about 24 hrs and 37 min which is very similar to a day on Earth. These factors have shown that Mars is a suitable candidate for supporting human life.

Credit: Cornell University
Found on NASA astrobiology website

 

How will people get there?

People will travel to destinations such as Mars via rockets. Space flight is very expensive and can cost almost 100’s of millions of dollars just to send one rocket to a planet like Mars. Despite the overwhelming cost of rocket launches, many companies such as SpaceX and government agencies such as NASA and China National Space Administration (CNSA) have invested in Mars research. Technological innovation is leading to a decrease in these prices. SpaceX has a plan to send its first crew to Mars in the year 2024 while NASA has a more long term plan which includes sending crews to the Moon first as a preparation for larger missions to Mars.

Life on Mars

Due to the amount of radiation on Mars surface humans cannot walk around unprotected. The thin atmosphere on Mars would have to be shielded from solar winds and life on Mars would be mostly spent living in capsules. Over time, Mars can be transformed into a fully habitable planet like Earth.

– Sandeep Singh