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  • Jasmine Lee 1:00 am on November 25, 2015 Permalink | Reply
    Tags: Canada, , , ,   

    Product Recall due to Undeclared Allergens 

    Product recalled due to undeclared allergens (CFIA, 2015)

    Mustard, sesame, soy and wheat not declared on label. (CFIA, 2015)

    Early this year on January 19th, the Canadian Federal Inspection Agency (CFIA) issued a notice to recall Mann’s Mediterranean Style snap peas due to not declaring the presence of allergens, specifically mustard, sesame, soy and wheat in the toppings and dressing. The allergens were first identified by the manufacturer and they had immediately halted distribution to their exclusive Walmart and Sobeys retailers across Canada. Fortunately, there had not been any reported hospitalizations or deaths, but individuals with hypersensitivities were advised to dispose or return the product to the retailer. Given that the best before date was January 25th, remaining products should have reached the end of its shelf life by the end of the week.

    Mechanism and Characteristics of Food Allergies

    Food allergy is a health concern that should not be overlooked. According to Soller et al.’s cross-sectional study (2012), adverse reactions to one or more allergens were self-reported by 6.67% of Canadians. Unfortunately, these numbers are expected to increase (Hengel, 2007).

    Food allergies are classified as a category of hypersensitivity where the immune response recognizes and abnormally believes the offending food or component to be harmful. The mechanism of an allergic response commences when the ingested allergen, which is typically a protein, crosses the intestinal barrier to the bloodstream and is recognized by circulating lymphocytes or white blood cells. These immune cells trigger the release of IgE antibodies that bind to mast cells. Through antibody-receptor interactions, inflammatory mediators, i.e. histamine, will be secreted to the surrounding tissues and result in adverse symptoms involving the skin, gastrointestinal, respiratory and/or cardiovascular systems. Initial exposure to the allergen is usually asymptomatic, but subsequent exposures may result in a quicker and more severe response. This is because some IgE-coated mast cells are already present and bind immediately to the same antigens to release histamine. Allergic symptoms may appear immediately after a few minutes or can be delayed up to 24 hours. They can be mild and localized to one or more body systems, such as nausea and vomiting from the gastrointestinal system. Alternatively, symptoms may progress in severity to affect all body systems, resulting in anaphylaxis or death. (Taylor, 2006)

    Fact or Myth: Consuming processed foods reduce the risk of developing allergenic reactions.

    Adding to the complexity of allergies, food processing will interfere with the allergenic capacity. IgE antibodies tend to bind well to a particular region on antigens, known as epitopes. These may be linear amino acid chains or 3D conformational structures. The binding affinity of IgE antibodies may be reduced during processing. For instance, high heat denatures the 3D conformation and fermentation cleaves the amino acid sequences. At the same time, allergenic capacity may be promoted as some epitopes are no longer hidden by the protein’s 3D conformation and can bind to IgE. Additional structures and IgE binding sites may be created from protein and peptide modifications during processing. Overall, further studies are necessary to develop a clearer answer for processed foods. (Hengel, 2007).

    Prevention Strategies

    Given the importance of allergens and potentially life-threatening consequences, CFIA is enforcing mandatory labelling for the top 10 allergens: wheat, soy, peanuts, tree nuts, sulphites, eggs, seafood, mustard, milk and sesame. Food manufacturers also need to take precautionary measures to avoid cross-contamination at the plant and practice proper product labeling. Consumers should periodically review the list of product recalls on the CFIA’s webpage. While there are currently no approved treatments, individuals with severe allergies should follow a strict diet and carry an EpiPen in case of a sudden reaction. Overall, prevention and awareness are pertinent to reducing food allergies.

    What are your thoughts on the prevalence of food allergies? Do you think processed foods may be associated with the upward trend of food allergies?

    Check out the following references and video (particularly about unpasteurized milk from times 14:40-15:13 and parasitic worms on allergies from times 23:09-25:44).

    https://youtu.be/q25mCI_WWKY

    References

    CFIA. (2015). Food Recall Warning (Allergen) – Mann’s brand Mediterranean Style Snap Pea Sensations recalled due to undeclared mustard, sesame, soy and wheat. Retrieved from http://www.inspection.gc.ca/about-the-cfia/newsroom/food-recall-warnings/complete-listing/2015-01-19/eng/1421730513089/1421730556698

    Health Canada. (2012). Food Allergies and Intolerances. Retrieved from http://www.hc-sc.gc.ca/fn-an/securit/allerg/index-eng.php

    Hengel, A. J. (2007). Food allergen detection methods and the challenge to protect food-allergic consumers. Analytical and Bioanalytical Chemistry 389(1):111-118.

    Soller, L., Ben-Shoshan, M., Harrington, D. W., Fragapane, J., Joseph, L., St. Pierre, Y., Godefroy, S. B., La Vieille, S., Elliott, S. J. & Clarke, A. E. (2012). Overall prevalence of self-reported food allergy in Canada. Journal of Allergy and Clinical Immunology 130(4):986:988.

    Taylor, S. (2006). The nature of food allergy. In S. J. Koppelman & S. L. Hefle (Eds.), Detecting Allergens in Food (pp.3-20). Boca Raton, FL:Woodhead Publishing Limited, Boca Raton.

     
    • ColleenChong 12:03 pm on November 25, 2015 Permalink | Reply

      Hi Jasmine, I really like how you were able to incorporate the topic of allergens into to your blog. Allergens are a major source of recalls, specifically undeclared allergens. It is good to see how proactive CFIA is with recall and was done so before anyone in the public was affected. It seems like food allergy seems to be increasing but It might be the fact that there’s better technology to help detect the cause of allergy in individuals. The list of allergens seems to be slowly growing, which may also increase the number of individuals who may have allergens. I think processed foods is associated with an upward trend of food allergies because many companies that process allergens may also use the same equipment to process foods without allergens. The residual allergen may be transferred into the second process. To prevent this properly cleaning and sanitation is essential. But the best solution would be having one process line with allergen containing food and the other one without.

    • TamaraRitchie 9:35 am on November 26, 2015 Permalink | Reply

      It is nice to see the CFIA being so quick to get this product off the shelves. I feel with a product such as snap peas, many people would not assume there would be any allergens in the product. As we learned in class and as you explained above allergic reactions can be very severe and lead to death. It is just as important for the CFIA to be on top of allergen recalls as it is for food borne illnesses. Both types of illness can be extremely harmful to the public. Overall I hope in the future we can have more research on what is causing the upswing of allergens. I am very curious as to what is causing it, it may be an increased in processed foods or it may be something we have not even thought of yet. I would not be surprised if the increase of processed foods were in some way contributing to the increase in allergens.

    • catherine wong 3:32 am on November 27, 2015 Permalink | Reply

      Since allergens can cause such severe illnesses or death as Jasmine mentioned above, it is kind of reassuring to know that CFIA is working hard and efficiently in taking products with undeclared allergens off of store shelves. I actually wonder how they found out about the undeclared allergens. Did the producer test their products for allergens or did they look over their production records for that day and found that they did not clean their equipment between switching from producing a product with allergen to a product without that allergen? I do agree with Colleen that during production, having one process line just for the allergen would be the best to reduce contamination. Even though a designated allergen line would cost money and not all processing plants can afford that which is why the cleaning process is so important for them. With all the undeclared allergen recalls that CFIA always has on their website, I feel that a designated allergen line in plants might be worth it because undeclared allergens is a very serious matter.

    • Stephanie Chen 6:57 pm on December 1, 2015 Permalink | Reply

      As the incidence of food allergies seems to be on the rise, particularly in children, it is critical for allergen labelling to be strictly enforced. I feel that a designated allergen line could still have potential cross contamination within a plant. We often see products with labels such as “may contain [allergen]” or “processed in a plant that also uses [allergen].” It may be in the best interest of those with known allergies to avoid these foods altogether (though snap peas may come as a surprise). On another note, it is really interesting that you presented the fact of myth concerning the potential link between processed foods and allergy development. I also wonder what factors could be associated with the increase of allergens, whether genetically, environmentally, or even due to the changes in the foods we eat?

    • EmilyLi 2:19 pm on December 2, 2015 Permalink | Reply

      In my opinion this is a very informative post. It is great to know that CFIA is so quick and efficient with the issuing the recall. Allergen in food had been a concern especially for parents with severe allergic children. I think that it’s great that the CFIA is strict on the labeling to ensure consumers health safety. However the factor we may need to bring to attention is the genetically modified foods. Genetically modified food consist of genetic material that wasn’t originally found in the food. This may alter the different protein that a certain food product can contain thus initiating a allergic reaction. I wonder how we could put a standard or have a regulations for this kind of foods.

    • flyingsquirrel 3:59 pm on December 2, 2015 Permalink | Reply

      Interesting how you brought up that processing the foods may render them less likely to cause allergic reactions through changing protein composition (through processes such as heat etc.). This would explain why some people are able to eat certain foods they are normally allergic to as long as it is deep fried. One hypothesis at the moment as for why there seems to be a higher number of people allergic to foods may be due to over protection. This idea comes from the increasing amount of mothers keeping their children from being exposed to said products at an early age (thus not allowing them to build better immunological systems that can tolerate the food proteins). Therefore popular foods associated with allergies in certain demographic areas (ex. peanuts in the west) will be avoided most often, this may end up bringing adverse effects and perpetuate the development of food allergy that one is trying to avoid. I don’t know how true this idea is, but it makes you re-think what to give children to eat.

    • KristinaRichmond 8:17 pm on December 4, 2015 Permalink | Reply

      Great article! I also found it interesting how processing can change the allergenic potential of food. I think this would be a good area for further research since food allergies can be so severe and life-threatening, and it’s easy to get accidentally exposed if you’re not the cook or really diligent about reading labels. I think one problem with processed foods is that they can be quite complex and contain many different (and sometimes unusual) ingredients, so I think it’s good that the CFIA enforces labelling for the top 10 allergens.

    • RainShen 9:03 pm on December 10, 2015 Permalink | Reply

      As we learned in this course, food allergy would be fetal sometimes, so it is very critical to state all the allergens in the food product, especially for those highly processed foods. Sometimes the ingredients in the dressing or sauce, or even contacting with other foods in the same production environment will cause food allergy for the consumers. Comparing to food safety, food allergy does not have very strict rules for the manufacturers to state every allergen that might be possible contained in the products so sometimes it might be a big concern for costumers, especially for children and infants. Since food allergy is not dose related, even a very small amount of the allergen may cause very severe results. However, according to your post, CFIA recalled the suspected products before any hospitalizations or deaths happen. In my opinion the food inspection of CFIA is very sufficient in this way.

    • yichen25 1:47 am on December 11, 2015 Permalink | Reply

      Food allergy is very prevalent to those who are not able to develop a clinical tolerance towards the food protein that has been ingested. Failure to develop a clinical tolerance will lead to a series of hypersensitivity reactions which can be be potentially life-threatening if not treated immediately. Besides, the application of food processing as mentioned above has the ability to interfere with the binding of the antibodies to the antigens. However, more research should be done to further confirm the effect of food processing in the allergenic capacity. As for now, I personally think that both labeling of the food allergens and listing out the ingredients in the food product are very effective to inform consumers on the presence of allergenic compounds in the food product.

    • WinnieLiao 7:45 pm on December 14, 2015 Permalink | Reply

      As learnt in other courses as well as in this course, allergens indeed can induce many severe or fatal issues and contamination of these foods with allergens would definitely require a recall. Thankfully in Canada CFIA is quick to react and is helpful in facilitating recall of these food items. The consequences of food allergic reactions can range from mild to severe; I’ve seen red spots and rashes developing on people’s skin after ingesting these foods with allergens. Also it’ interesting to know that food processing steps can expose the epitopes promoting the binding with IgE. However, the processing can also decrease the IgE binding affinity with antigens. Besides the food processing procedures, I wonder if there are other factors that can potentially bring in allergens from other food sources and how these outbreaks associated with allergens can be traced.

    • CandiceZheng 3:01 pm on December 15, 2015 Permalink | Reply

      First of all, it is great to know that CFIA and the manufacture realized the problem very quickly and issued the recall so efficiently that there were no reported hospitalizations or deaths. This is a very informative post that introduced a lot of information related to food allergen, and I really like the subtitles that makes the post very clear and organized. In addition, I like the discussion about how food processing would alter the allergenic potential of food in various perspectives.

  • flyingsquirrel 6:30 pm on October 19, 2015 Permalink | Reply
    Tags: Canada, , PHAC, ,   

    A Canada Exclusive: Salmonella Across the Country, Majority on the East-side! 

    Just last Friday on October 16th, news outlets have published an article about a recent outbreak on Salmonella, with reports starting from June 12, 2015. The Salmonella outbreak has spread over the country in 8 provinces by the 20th of September with the most cases reported in Ontario. Other provinces include British Columbia, Alberta, Saskatchewan, Manitoba, Nova Scotia, New Brunswick, and Quebec. Luckily, there has been no reported deaths.

    The source of outbreak is still unknown as of today, however many common food carriers of Salmonella pathogens include: poultry and poultry products (ex. eggs), beef, pork, nuts, and produce (ex. fruits and vegetables.

    A Study has shown that Salmonella can be a tricky pathogen as it can become resistant to standard sterilization procedures in food industries through cross-protection. Cross-protection occurs when a pathogen experiences sub-lethal conditions—in which it develops resistance to harsh environments—followed by conditions that would have otherwise killed it (Fong, 2015). In the case of Salmonella, lethal conditions include but are not limited to: pH <6.5, temperature>70 degrees Celsius, and water activity <0.93.

    This means that Salmonella can be found not only on food sources, but surviving on surfaces that have come into contact with the contaminated products! It is a very versatile pathogen, which means that the source of outbreak could be identified in any step of the food chain:

    1. Agricultural Sector
    2. Manufacturing/processing Sector
    3. Distribution and Transportation Sector
    4. Retail Sector
    5. At home/restaurants in which the foods are prepared and consumed

    2Salmonella can cause symptoms within 6-72 hours of ingestion. Common symptoms include: fever, chills, diarrhea, abdominal cramps, headache, nausea, and vomiting which can last 4-7 days. In more severe cases, such as for those with compromised immune systems, are elderly, or are children, may have to be hospitalized and in the worst case scenario, death may occur. In some cases, people may be asymptomatic and spread the bacteria onto others by not practicing hygienic procedures (handwashing, keeping equipment clean, etc.). (Public Health Agency of Canada, 2015).

    This outbreak is a very curious incident as it has spread so far across the country, yet the source(s) is/are not pinpointed to exact foods or modes of process/transportation. With the largest cases found in Ontario and incidences tapering off towards the west, it would seem that the source of outbreak would be from the east. However there may also be a chance that the outbreaks are due to improper food handling methods at home. Another interesting finding is that over half of the effected are female.

    With such a large difference of outbreaks between the east and west, could there be a difference between provinces for public education in food handling procedures? Could there be any meaning behind why half of those affected were women?

    Before this reported outbreak, there had been another in January 2015. These incidents have been identified rather quickly. However there is an ongoing debate about whether inspection has become quicker and well executed, or if the increased frequency in outbreaks is due to recent cuts in finance for CFIA. More about the cuts can be read on from this article.

    What other underlying factors contribute to outbreaks?

    How should industry procedures change in order to minimize the effect of cross-protection?

    In addition, this link is very helpful with explaining the bacteria and names some organizations involved in food safety for those of you who are looking at the policies currently in place for protecting consumers.

    Any related and passionate comment is welcome!

     

    Works cited:

    Public Health Agency of Canada. 2015. http://www.phac-aspc.gc.ca/fs-sa/phn-asp/2015/salm-0628-eng.php

    Image obtained on October 19, 2015 from http://thumbs.dreamstime.com/thumblarge_1666/16666999.jpg

    Fong, K. 2015. Environmental adaptation and stress response of Salmonella enterica in peanut oil, peanuts, and chia seeds. University of British Columbia.

     

     

     
  • NorrisHuang 11:08 pm on October 12, 2015 Permalink | Reply
    Tags: Alberta, , Canada, contamination, , , , , Vancouver,   

    Escherichia coli on fresh produce 

    Escherichia coli (E. coli) are gram-negative, rod-shaped bacteria that cause a great number of food-borne illnesses annually. For example, according to PHAC, there were 470 reported cases of E. coli O157:H7 infections in Canada in 2013, which was the third highest among all pathogenic bacteria. Although E. coli infection is often referred to as “hamburger disease”, these bacteria also contaminates fresh produce. Earlier this year (between March 13 and 31), there were several E. coli infections cases identified in Canada, majority (9 out of 12 cases) of which were reported in Alberta. More investigations by CFIA are underway, however, leafy greens are considered to be the most possible cause of infections. Depending on strains, consequences of E. coli infections vary. Most people suffer from stomach discomfort, diarrhea and vomiting. Those who are infected with pathogenic strains such as O157:H7 may develop more severe symptoms, such as kidney failure.

    In addition to bacterial contamination, a research done by a group of UBC researchers shows a concerning fact that 97% of E. coli isolated from leafy greens samples purchased from several farmers market in Vancouver were antibiotic-resistant. To be more specific, antimicrobial resistance of E. coli on fresh green, red, and romaine lettuce samples were evaluated. 58% of samples were resistant to amikacin, 48% were resistant to trimethoprim and 45% were trimethoprim-sufamethoxazole-resistant. Resistance to nalidixic acid, kanamycin, ampicillin, amoxicillin-clavulanic acid, cefoxitin, gentamicin and tetracycline were also found. Luckily, only 13% of samples were found to be contaminated with trace amount of E. coli and the microbiological quality of produce was acceptable according to Health Canada guidelines.

    You can read more about the 12 E. coli cases in Canada here: http://globalnews.ca/news/1942601/health-officials-suspect-e-coli-illnesses-linked-to-leafy-greens/

    The use of antimicrobial agent on food animal (e.g. chicken) is one possible cause of antibiotic-resistance in E. coli on fresh produce. Antimicrobial agent is used to promote growth of food animal. Nonetheless, only 10% of the drug would be absorbed by animals and the rest will be excreted. As the wastes are applied as fertilizers. Antibiotics are also introduced to the environment (e.g. soil, water) and vegetables. Antibiotics selects for drug-resistant bacteria on leafy produce, which leads to predominant of antibiotic-resistant bacteria. Additionally, contaminated irrigation water, poor personal hygiene and inadequate food processing also adversely affect microbiological safety of greens.

    To protect ourselves from E. coli contaminations on vegetables, the following precautions can be taken:

    • Wash produce thoroughly before consumption
    • Clean and sanitize food-contact surfaces properly, including cutting boards, knifes, etc.
    • Wash hands for at least 20 seconds with warm water and soap regularly during food handling
    • Keep raw meat and vegetables separated to avoid cross-contamination
    • Store food at refrigerating temperature (< 4 ͦC) to inhibit bacterial growth

    For more information about E. coli, see: http://www.phac-aspc.gc.ca/fs-sa/fs-fi/ecoli-eng.php

     
    • Duncan 1:37 pm on October 13, 2015 Permalink | Reply

      This is a test of the blog’s comment system

    • Duncan 1:39 pm on October 13, 2015 Permalink | Reply

      This is a test of the blog’s comment system, take 2.

    • wen liao 2:51 pm on October 16, 2015 Permalink | Reply

      Haha this is like a very classical example about the effect of antimicrobial misuse as we have talked in class. I have also read similar articles talking about how the bacteria isolated from vegetables are resistant to one or multiple antimicrobials, which sounds quite scary to me, to be honest. However, although the issue with antimicrobial misuse has been prevalent for years and scientists have been addressing this problem at different scenarios, not very many people have taken it seriously. I have a friend who recently got flu, and his doctor prescribed him with antibiotics LOL….In addition although the stuff turkey season is almost gone, I till recall this news I read about how you should not wash store packaged turkey before you baked it in the oven. While wash the turkey with running water cannot remove the bacteria on the surface of the turkey skin, this action might spread the cells all over on the turkey causing more contamination. I don’t know if it would be the same case for your e. coli suggestions haha.

    • dgozali 9:07 pm on October 18, 2015 Permalink | Reply

      I think your article brought up a very important issue of growing antimicrobial resistance. Its quite alarming that a large proportion of E. coli found on leafy greens are resistant as most people consume these vegetables raw and some might not even bother washing them as they’re often labelled as a “ready to eat” food. Hence this makes it much easier for people to get sick from consuming these products. This reminds me of the recent outbreak at UBC’s centenniel celebration where many people got sick from eating the produce from the UBC farm. Perhaps the microbes were resistant strains as well. Either way, this is an increasingly prominent issue that should be taken more seriously!

    • CindyDai 10:42 am on October 23, 2015 Permalink | Reply

      The increasing antimicrobial resistance of E. coli indicates the increasing difficulty of controlling E. coli in food industry. To protect our families, handling food safely is crucial to eliminate any E. coli survived the factory processing in leafy greens. In the original news, there are a few more useful tips from PHAC on safe food handling. I learned that we should always reheat leftovers until steaming hot before eating. Especially for leafy greens, we should always keep them refrigerated and only take them out of fridge right before consumption. When there are E. coli outbreaks, cooking vegetables is a better choice. Food safety is in our hands!

    • ya gao 9:00 pm on October 23, 2015 Permalink | Reply

      After reading this post, I think it is important for government agencies like CFIA to realize the presence of antimicrobial resistant strains of E. coli on leafy green products. Although only 13% of samples were found to be contaminated with trace amount of E. coli and the microbiological quality of produce was acceptable according to Health Canada guidelines, it is a serious problem once breaks out. Leafy green products are usually considered as ready to eat foods and people consume them without heat processing step. With the increasing problem of antimicrobial resistant strains of E. coli on ready to eat foods, food safety may be threaten. CFIA should find a way to resolve this problem by controlling the use of fertilizer from animal waste, as well as doing sample testing on leafy green products more frequently.

    • AngeliMalimban 6:11 pm on December 12, 2015 Permalink | Reply

      I think it is interesting how people have a common misconception about how E. coli can only be found in raw beef. I remember my friend freaking out about my other friend preparing raw beef burgers, while she ate the salad that was from fresh produce. Could she have washed it well enough? Even then, it probably would still contain E. coli since it does not come out unless it is cooked.
      Salads are such a big fad in our society due to its nutritional value, but people should not be surprised if they get sick eating this. It’s also hard to cook vegetables because its nutritional value is best when raw, as most of the vitamins and minerals could dissolve in the water (if boiled) and let’s be real… it’s just SO much easier to eat vegetables raw so we do not have to go through the labour of cooking it!

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