Publications

Lee JH, Park ES, Choi JR, Matthews K, Lam AV, Deng X, Duffy SP, Ma H, See-N-Seq: RNA Sequencing of Target Single Cells Identified by Microscopy via Micropatterning of Hydrogel Porosity. Communications Biology, 5, 768, 2022 [Link to article]

Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H, Assessing Red Blood Cell Deformability using Deep Learning. Lab on a Chip, 22, 26-39, 2022. [Link to article; BioRxiv]

Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H, Data for Assessing Red Blood Cell Deformability using Deep Learning. Data in Brief, 47, 108928, 2023. [Link to article]

Lee R, Witherspoon L, Robinson M, Lee JH, Duffy SP, Flannigan R, Ma H, Deep Learning-based Automated Rare Sperm Identification from Testes Biopsies. Fertility and Sterility, 118, 90-99, 2022. [Link to article; BioRxiv]

Matthews K, Lamoureux E, Myrand-Lapierre M, Duffy SP, Ma H, Technologies for Measuring Red Blood Cell Deformability. Lab on a Chip, 22, 1254-1274, 2022. [Link to article]

Islamzada E, Lamoureux ES, Matthews K, Duffy SP, Mark D. Scott, Ma H, Blood Unit Segments Accurately Represent the Biophysical Properties of Red Blood Cells in Blood Bags but Not Hemolysis. Transfusion, 62, 448-456, 2022. [Link to article; BioRxiv]

Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Mark D. Scott, Ma H, Degradation of Red Blood Cell Deformability during Storage in Blood Bags. eJHaem, 3, 63-71, 2022. [Link to article; BioRxiv]

Choi JR, Lee JH, Xu A, Matthews K, Xie S, Duffy SP, Ma H, Monolithic Hydrogel Nanowells-in-Microwells Enabling Simultaneous Single Cell Secretion and Phenotype Analysis, Lab on a Chip, 2020. [Link to article]

Berryman S, Matthews K, Lee JH, Duffy SP, Ma H, Image-based Cell Phenotyping Using Deep Learning, Communications Biology, 3, 674, 2020. [Link to article; bioRxiv]

Satti SR, Deng P, Matthews K, Duffy SP, Ma H, Multiplexed End-point Microfluidic Chemotaxis Assay using Centrifugal Alignment, Lab on a Chip, 20 3096-3103, 2020. [Link to article; bioRxiv; PMID: 32748936]

Chiu JCY, Teodoro J, Lee JH, Matthews K, Duffy SP, Ma H, Selective Laser Gelation of Methylcellulose Enabling Selective Propagation of Antibody-Producing Cells, Lab on a Chip, 20, 1544-1553, 2020. [Link to article; bioRxiv; PMID: 32270803]

Lee JH, Santoso AT, Park ES, Matthews K, Duffy SP, Ma H, Lossless Immunocytochemistry using Photo-polymerized Hydrogel Thin-films, Analyst, 145, 2897-2903, 2020. [Link to article, bioRxiv; PMID: 32129326]

Islamzada E, Matthews K, Guo Q, Duffy SP, Ma H, Deformability based Sorting of Stored Red Blood Cells Reveals Donor-dependent Aging Curves, Lab on a Chip, 20, 226-235, 2020. [Link to article, bioRxiv; PMID: 31796943] Article profiled by AABB NewsCityTV, EurekAlert, IFL Science, Bioengineer.org, Science Codex, Phys.org, The Medical News, Business Standard, Outlook India, Medindia, Hans India, Mirage News, Daily Excelsior, Devdiscourse, Medical Device Network, UBC News

Park ES, Yan JP, Ang RR, Lee JH, Deng X, Duffy SP, Beja K, Annala M, Black PC, Chi KN, Wyatt AW, Ma H, Isolation and Genome Sequencing of Individual Circulating Tumor Cells using Hydrogel Encapsulation and Laser Capture Microdissection, Lab on a Chip, 18(12), 1736-1749, 2018. [Link to article; PMID: 29762619]

Kang N, Guo Q, Islamzada E, Ma H, Scott MD, Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation, Integrative Biology, 10(4) 207-217, 2018. [PMID: 29570200]

Guo Q, Matthews K, Islamzada E, Duffy SP, Deng X, Ma H, Deformability based cell sorting enabling phenotypic fractionation of leukocytes, Scientific Reports, 7, 6627, 2017. [Link to article; PMID: 28747668]

Matthews K, Duffy SP, Myrand-Lapierre M, Ang RR, Li L, Scott MD, Ma H, Microfluidic analysis of red blood cell deformability as a means to assess hemin-induced oxidative stress resulting from Plasmodium falciparum intraerythrocytic parasitism, Integrative Biology, 9, 519-528, 2017. [PMID: 28524208; pdf]

Park ES, Jin C, Guo Q, Ang RR, Duffy SP, Matthews K, Azad A, Abdi H, Todenhöfer T, Chi KN, Black PC, Ma H, Continuous Flow Deformability-Based Separation of Circulating Tumor Cells Using Microfluidic Ratchets, Small, 12(14), 1909-1919, 2016. [PMID: 26917414; pdf]

Todenhöfer T, Park S, Jin C, Ang RR, Duffy SP, Matthews K, Abdi H, Ma H, Black PC, Microfluidic enrichment of circulating tumor cells in patients with clinically localized prostate cancer, Urologic Oncology, 16, 30121, 2016. [PMID: 27658563]

Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H, Deformability based Sorting of Red Blood Cells Improves Diagnostic Sensitivity for Malaria Caused by Plasmodium Falciparum, Lab on a Chip (Communication), 16, 645-654, 2016. [PMID: 26768227; pdf]

Santoso AT, Deng X, Lee JH, Matthews K, Duffy SP, Islamzada E, Myrand-Lapierre M, McFaul SM, Ma H, Microfluidic Cell-phoresis Enabling High-throughput Analysis of Red Blood Cell Deformability and Biophysical Screening of Antimalarial Drugs, Lab on a Chip, 15(23), 4451-4460, 2015. [PMID: 26477590; pdf]

Deng X, Duffy SP, Myrand-Lapierre M, Matthews K, Santoso AT, Du Y, Ryan KS, Ma H, Reduced Deformability of Parasitized Red Blood Cells as a Biomarker for Antimalarial Drug Efficacy, Malaria Journal, 14(1), 428, 2015. [Link to Article; PMID: 26520795]

Matthews K, Myrand-Lapierre M, Ang RR, Duffy SP, Scott MD, Ma H, Microfluidic Deformability Analysis of the Red Cell Storage Lesion, Journal of Biomechanics, 48(15), 4065-4072, 2015. [PMID: 26477408; pdf]

Qin X, Park S, Duffy SP, Matthews K, Ang RR, Todenhöfer T, Abdi H, Azad A, Bazov J, Chi KN, Black PC, Ma H, Size and Deformability based Separation of Circulating Tumor Cells from Castrate Resistant Prostate Cancer Patients using Resettable Cell Traps, Lab on a Chip, 15, 2278-2286, 2015. [PMID: 25876237; pdf]

Myrand-Lapierre M, Ang RR, Deng X, Matthews K, Santoso AT, Ma H, Multiplexed Fluidic Plunger Mechanism for High-Throughput Analysis of Red Blood Cell Deformability, Lab on a Chip, 15(1), 159-167, 2015. (PMID: 25325848[pdf] [SI Video]

Wu T, Guo Q, H Ma, Feng JJ, The Critical Pressure for Driving a Red Blood Cell Through a Contracting Microfluidic Channel, Theoretical and Applied Mechanics Letters, 5, 227-230, 2015. María Belén Jiménez-Díaz, Daniel Ebert, Yandira Salinas, Anupam Pradham, Adele Lehane, Marie-Eve Myrand-Lapierre, Kathleen G. O’Loughlin, David M Shackleford, Mariana Justino Lage de Almeida, Julie Clark, Adelaide Dennis, Jonathon Diep, Xiaoyan Deng, Aaron N. Endsley, Greg Fedewa, Armand Guiguemde, Maria Gracia Gomez-Lorenzo, Gloria Holbrook, Jeremy Horst, Charles Kim, Jian Liu, Marcus C S Lee, Amy Matheny, Maria Santos Martínez, Ane Rodriguez-Alejandre, Laura Sanz, Martina Sigal, Natalie Spillman, Phillip D. Stein, Zheng Wang, Fangyi Zhu, David Waterson, Spencer Knapp, David Fidock, Francisco Javier Gamo, Susan A Charman, Jon C. Mirsalis, Hongshen Ma, Kiaran Kirk, Santiago Ferrer, Iñigo Angulo-Barturen, Dennis Kyle, Joseph L DeRisi, David M. Floyd, R. Kiplin Guy, (+)-SJ733: A Clinical Candidate for Malaria that Acts Through ATP4 to Induce Rapid Host-Mediated Clearance of Plasmodium, Proceedings of the National Academy of Sciences of the United States of America, 111(50), E5455-62, 2014. (PMID: 25453091[Link to Article]

Guo Q, Duffy SP, Matthews K, Santoso AT, Scott MD, Ma H, Microfluidic Analysis of Red Blood Cell Deformability, Journal of Biomechanics, 47(8), 1767-1776, 2014. (PMID: 24767871[pdf]

Beattie WJ, Qin X, Lin W, Ma H, Clog-free Cell Filtration Using Resettable Cell Traps, Lab on a Chip, 14(15), 2657-65, 2014.(PMID: 24710608[pdf]

Park S, Ang RR, Bazov J, Chi KN, Black PC, Ma H, Morphological Differences Between Circulating Tumour Cells from Prostate Cancer Patients and Cultured Prostate Cancer Cells, PLoS ONE, 9(1), e85264, 2014. (PMID: 24416373) [Link to Article] [pdf]

Jin C, McFaul SM, Duffy SP, Deng X, Tevassoli P, Black PC, Ma H, Technologies for Label-free Separation of Circulating Tumor Cells: from Historical Foundations to Recent Developments, Lab on a Chip, 14(1), 32-44, 2014. (PMID: 23963515[pdf]

Lin BK, McFaul SM, Jin C, Black PC, Ma H, Highly Selective Biomechanical Separation of Cancer Cells from Leukocytes using Microfluidic Ratchets and Hydrodynamic Concentrator, Biomicrofluidics, 7, 034114, 2013. (PMID: 24404034[pdf]

Kwan JM, Guo Q, Kyluik-Price DL, Ma H, Scott MD, Microfluidic analysis of cellular deformability of normal and oxidative-damaged red blood cells, American Journal of Hematology, 8(88), 682-689, 2013. (PMID: 23674388[pdf]

Milavanovic L, Ma H, Method for measurement of friction forces on single cells in microfluidic devices, Analytical Methods, 4, 4303-4309, 2012. [pdf]

Lu PJ, Hoehl MM, MacArthur JB, Sims PA, Ma H, Slocum AH, Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination, AIP Advances, 2(3), 032110, 2012. [pdf]

Guo Q, McFaul SM, Park S, Ma H, Microfluidic micropipette aspiration for measuring the deformability of single cells, Lab on a Chip, 12(15), 2687-95, 2012. (PMID: 22622288[pdf]

McFaul SM, Lin BK, Ma H, Cell separation based on size and deformability using microfluidic funnel ratchets, Lab on a Chip, 12 (13), 2369-2376, 2012. (PMID: 22517056[pdf]

Guo Q, Reiling SJ, Rohrbach P, Ma H, Microfluidic Biomechanical Assay for Red Blood Cells Parasitized by Plasmodium falciparum, Lab on a Chip, 12 (6), 1143-1150, 2012. (PMID: 22318405[pdf] Press coverage: CBC Radio International, Chemistry World, CNET News, OMNI National News

Guo Q, McFaul SM, Ma H, Deterministic Microfluidic Ratchet Based on the Deformation of Individual Cells, Physical Review E, 83, 051910, 2011. [pdf]

Gerhardt T, Woo S, Ma H, Chromatographic Behaviour of Single Cells in a Microchannel with Dynamic Geometry, Lab on a Chip, 11 (16), 2731-2737, 2011. [pdf]

Ogunnika OT, Rutkove SB, Ma H, Fogerson P, Scharfstein M, Cooper RC, Dawson JL, A Portable System for the Assessment of Neuromuscular Diseases with Electrical Impedance Myography, Journal of Medical Engineering and Technology, Vol. 35, No. 7-8, 377-385, 2010. [pdf]

M. Yip, D.D. He, E. Winokur, A.G. Balderrama, R. Sheridan, H. Ma, A Flexible Pressure Monitoring System for Pressure Ulcer Prevention, Proceedings of the IEEE Engineering in Medicine and Biology Conference, Minneapolis, MN, 2009. (Won 2nd place at the student paper competition) [pdf]

H. Ma, J.H. Lang, A.H. Slocum, Calibration-free Measurement of Liquid Permittivity and Conductivity using Electrochemical Impedance Test Cell with Servomechanically Adjustable Cell Constant, IEEE Sensors. [pdf]

O.T. Ogunnika, M. Scharfstein, R.C. Cooper, H. Ma, J.L. Dawson, S.B. Rutkove, A Handheld Electrical Impedance Myography Probe for the Assessment of Neuromuscular Disease, in Proceedings of the IEEE Engineering in Medicine and Biology Conference, Vancouver, Canada, 2008. [pdf]

W. Wichakool, B.J. Pierquet, K.V. Durand, B.B. Hsu, R. Sheridan, H. Ma, Magnetic Endotracheal Tubes Imaging Device, in Proceedings of the IEEE Engineering in Medicine and Biology Conference, Vancouver, Canada, 2008. [pdf]

F.C. Chen, H. Wu, P.L. Hsu, B.A. Stronger, R. Sheridan, H. Ma, SmartPad: A Wireless, Adhesive-Electrode-Free, Autonomous ECG System, in Proceedings of the IEEE Engineering in Medicine and Biology Conference, Vancouver, Canada, 2008. [pdf]

H. Knight, J. Lee, H. Ma, Chair Alarm for Patient Fall Prevention based on Gesture Recognition and Interactivity, in Proceedings of the IEEE Engineering in Medicine and Biology Conference, Vancouver, Canada, 2008. [pdf]

H. Ma, J.H. Lang, A.H. Slocum, Permittivity Measurements using Adjustable Microscale Electrode Gaps between mm-Sized Spherical Electrodes, Review of Scientific Instruments, Vol. 79, No. 3, p. 035105, 2008. [pdf]

H. Ma, J.H. Lang, A.H. Slocum, Design of an Electrochemical Impedance Test Cell with Servomechanically Adjustable Cell Constant, in Proceedings of the IEEE Sensors Conference, pp. 1233-1236, Atlanta, GA, October 2007. [pdf]

H. Ma, A.H. Slocum, A Flexible-Input, Desired-Output (FIDO) Motor Controller for Engineering Design Classes, IEEE Transactions on Education, Vol. 49, No. 1, 113-121, 2006. [pdf]

J. White, H. Ma, J. Lang, A.H. Slocum, An Instrument to Control Parallel Plate Separation for Nanoscale Flow Control, Review of Scientific Instruments, Vol. 74, No. 11, 4869-4875, 2003. [pdf]

H. Ma, J. White, J.A. Paradiso, and A.H. Slocum, Sub-nanometer Displacement Sensing for the Nanogate, in Proceedings of IEEE Sensors, pp. 1086-1091, Toronto, Ontario, October 2003.

H. Ma, J.A. Paradiso, The FindIT Flashlight: Responsive Tagging Based on Optically Triggered Microprocessor Wakeup, in G. Borriello and L.E. Holmquist (Eds.): UbiComp, LNCS 2498, pp. 160-167, Gotenborg, Sweden, 2002. [pdf]

MIT ORCA team, ORCA-V: An Autonomous Underwater Vehicle, Journal paper for the 2002 AUVSI and ONR Autonomous Underwater Vehicle Competition, San Diego, CA, USA, 2002. [pdf]

H. Ma, “What the Heck are Photonic Crystals?”, Canadian Undergraduate Physics Conference, Quebec City, Quebec, November, 2000. (Won first prize for the best overall presentation)