Author Archives: anna tam

Thicker than Fish Skin

Does the underwater superhero name ‘Aquaman’ sound familiar to you? Notice that Aquaman is part fish, and part human. His scaly costume provides incredible strength, torpedo swimming speed, and impenetrable skin. Ever wonder what it’s like to have scaly fish skin, or even become half fish? Science is getting close!

Aquaman’s upper torso is covered with fish skin, which enables him to breathe and swim underwater at tremendous speeds. Image Credit: sfgate.com

A new medical innovation was recently discovered in Brazil, after the number of skin donors started to become scarce. The dean of plastic surgery in São Marcos Hospital, Dr. Maciel, collaborated with his research team to utilize the skin of Tilapia fish for treating burns. Tilapia skin showed progressive healing properties when applied on skin wounds. They call this an alternative treatment- with surprisingly good results!

A victim suffered from second degree burns after a gas canister explosion. Instead of wrapping her wounds with gauze, doctors applied an unusual bandage- using Tilapia fish skin! I mean, how weird is that? Her arm looked like a fish mutant straight out of the X-Men comics, if you ask me!

The fish skin is first sterilized by using chemicals, and then undergoes radiation treatment to kill viruses. Once cleaned and processed, they are vacuum-sealed, and can last for up to two years.

Tilapia was chosen as the prototype for the animal skin-grafting experiment because it is the most common, disease-resistant fish found in Brazil. Image Credit: feednavigator.com

Doctors then apply the fish skin to the burned skin area. The tilapia skin sticks on the wound and creates a buffering effect that blocks out contamination while keeping in moisture. It stays bonded to the wound until it completely heals over. The tilapia skin dries up and flakes off after 10 days, and reveals new scar tissue underneath. The greatest advantage is that you don’t have to change this bandage dressing daily, which reduces the trauma and pain suffered by patients. I think that’s an excellent plus!

After suffering from horrific burns from a canister explosion, Maria was the first patient to receive tilapia fish grafts on her damaged skin. Her arm is pictured below after treatment once the fish skin was removed, revealing healthy scar tissue. Image Credit: thesun.co.uk

Lab analyses revealed that tilapia skin is rich in Type 1 collagen and proteins, which help restore damaged skin for a speedy recovery. Type 1 collagen is important for wound healing because it provides skin with a stretchy, elastic-like quality.  It also enhances growth of connective fibres that hold skin together to prevent tearing. As a result, collagen stimulates healthy skin cells to grow and creates a new layer of scar tissue. The high level of humidity in fish skin helps to soothe wounds and eliminates the need for painkillers.

As of today, more than 50 patients have received tilapia fish-skin graft treatments for their painful burns, and all patients have shown successful healing results. It’s the first aquatic animal skin in the world to be tested in burn patients. Researchers say the skins are cost-effective and eco-friendly, and believe it will help burn victims to save time, medication costs, and hours of pain.

This video shows how tilapia skin is sterilized and then applied on the wounds of burn victims. Video Credit: statnews.com

The revolutionary treatment is currently only being practiced in Brazil, where tilapia skin is plentiful, and is donated to create more skin grafts. Brazilian plastic surgeons hope that this new pioneering treatment will spread to other countries in the nearby future.

-Anna Tam

Fatal Fentanyl: The Pill that Kills

Imagine this house party scene: I’m stuck at my best friend’s house for his birthday, and everyone is either passed out or wasted. My best friend comes up to me, insisting that I try fentanyl for the first time.

“Just one pill. It won’t hurt,” he says persuasively, and places the green pill on my palm.

Fentanyl is often crushed into powder using a pedicure file and then snorted for rapid ingestion. Image Credit: CalgaryPolice.ca

Peer pressure  gets the best of me, and I reluctantly swallow the green pill. “It can’t be that bad, could it?” I question myself.
As it turns out, swallowing that fentanyl pill was one heck of a big mistake!

Image illustrating that less than a dime-sized amount of fentanyl can fatally harm a person. Image Credit: abbypd.ca

A single green pill contains merely 50mg of fentanyl, which was more lethal than I thought! A deadly dose of fentanyl is just 2mg, which is equivalent to 2 grains of salt. Fentanyl works by binding to opioid receptors in the brain, which control a person’s breathing rate, emotions, and pain. This produces a state of peaceful happiness for the user, making fentanyl a highly addictive drug. However, fentanyl can stop a person’s breathing as a side effect, which can lead to death. Fentanyl is an opioid drug that is up to 100 times stronger than morphine! The high potency in a small amount of fentanyl misleads users to take a higher dosage, and greatly increases overdose risk.

Recreational drug use is on the rise, and many street drugs are unknowingly laced with fentanyl. Fentanyl’s potency makes it attractive for drug traffickers to smuggle many doses into a small package, but proves to be deadly for users.

Barcharts illustrating the number of deaths caused by fentanyl overdosage in BC. The number of deaths 2015 was ten times more than the number of deaths in 2012.
Image Credit: cbc.ca

B.C’s drug overdose crisis continues to take a terrible toll, and most are fentanyl-related deaths. Since July 2016, every 4/5 drug testings in Vancouver were positive for fentanyl. Teenagers and young adults aged 16 to 21 are the most vulnerable to drug abuse because of their high tendency for experimentation.

An important tool to help fight against B.C’s fentanyl crisis is the Naloxone kit, which contains medication that reverses the effects of opioid overdose. BC‘s Take Home Naloxone (THN) Program provides training and resources for overdose emergencies. Naloxone is now available to the public without prescription. It is easy to use, has small side effects, and provides a life-saving solution! Increasing access to naloxone is the fastest way to reduce the dramatic number of fentanyl-related deaths.

BC’s Naloxone Program distributes lifesaving kits and trains people to use overdose-reversal medication. This video shows how to recognize and respond to an overdose. Video Credit: towardtheheart.com/

Poster outlining the dangers of drugs cut with fentanyl. Image Credit: knowyoursource.ca

As I mentioned before, fentanyl binds to opioid receptors, which puts the person in a state of ‘suffocating happiness’. Naloxone works by knocking out fentanyl from opiate receptors in the brain and restores normal breathing rate. Without Naloxone, brain cells die without proper oxygen circulation, and the drug user receives serious brain damage and memory loss.

If you decide to take recreational drugs, be sure to carry a Naloxone kit with you. In addition, don`t be afraid to call 911 if you sense that someone is overdosing. Don’t let either you, or your friend, become another fentanyl victim.

-Anna Tam