Author Archives: ghsi

Glaciers of British Columbia

The distinctive topography of British Columbia is in large part due to the presence of massive volumes of ice during the last ice age. Locally, this last major glacial advance is called the Fraser Glaciation. Although there have been at least four major advances of ice since the beginning of the Pleistocene (1.8 million years ago), each successive advance has wiped out evidence of the previous advance. Most of the erosion and depositional landforms we see today are the result of the last, Fraser Glaciation.

Glaciers erode, transport, and deposit clay, silt, sand, and gravel, forming many different landforms. The study of these deposits is called Quaternary geology. The gradual advance of ice started in southern BC about 25,000 years ago and climaxed at about 15,000 years ago in Washington state (see figure). This ice was part of the larger Cordilleran Ice Sheet, which formed as valley glaciers advanced downhill and coalesced to form a large ice mass that covered almost all of BC. A piedmont glacier is also called an expanded foot glacier. It is a continuous sheet of ice at the base of a mountain range and resting on land that is formed by spreading out and coalescing of valley glaciers from the highest elevations of the mountains.

To the west advanced into the Pacific Ocean, although there may have been ice-free corridors at times. To the east the ice joined up with the Laurentide Ice Sheet (see video) that was advancing from Hudson Bay. At times there may have been an ice-free corridor between the sheets along the Rocky Mountains. This is important to archaeologists, as either the coastal or interior corridors may have provided migration routes for ancestral North Americans during this time. By 10-11,000 years ago the ice had left the Fraser Valley.

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As the ice advanced to lower elevations throughout the mountain ranges of the Cordillera, the spectacularly rugged scenery was formed. Small river valleys became filled with ice that gouged out large U-shaped valleys separated by narrow knife-edged ridges and triangular peaks. The local Capilano and Seymour Rivers and Lynn Creek all begin in U-shaped valleys, although their lower reaches include narrow gorges and glacial drift deposits. Steep sided circular depressions high in the mountains on the Cheakamus map sheet are called cirques and are the birthplace of mountain glaciers.

As the ice advanced, large volumes of outwash sand were spread out in front of the glaciers by meltwater rivers. In southwest BC, as the ice moved down the Georgia Depression from north to south, over 500 metres of sand, silt, and gravel were deposited in this fashion. It is probable that in the northern part of the Georgia Strait, dry land existed across the strait. The sands that filled up the depression are called the Quadra Sands and can be seen in the sea cliffs at UBC and at Point Roberts.

References:

Siegert, Martin. Ice Sheet and Late Quaternary Environmental Change. London: Wiley, March 2001.

The Neurological Basis of Williams Syndrome

Williams Syndrome is a rare non-fatal congenital condition in which affected children are mildly to moderately retarded and score below average on IQ tests. They usually read and write poorly and struggle with simple arithmetic,  yet they display unique abilities in other areas of intelligence, especially emotional intelligence involving socializing and empathy. The disorder affects males and female from all racial backgrounds at an equal probability.

The disorder is caused by deletion of a tiny piece from one of the two copies of chromosome 7 present in every cell of the body. Twenty-give or more genes are deleted and loss of one in particular (ELN) which codes for elastin, a connective protein gives rise to cardiovascular problems.

Such cardiovascular problems include heart murmurs and narrowing of major blood vessels, and supravalvular aortic stenosis, a constriction of the aorta. Babies may have difficulty feeding or suffer from stomach pains and hernias.  As they develop, they show delayed physical and mental development with unsteady voices. They walk awkwardly for the rest of their lives and fine motor control is impaired. They are also highly sensitive to noise, grow to a  shorter height than average and seem to have gray hair and wrinkles earlier. Lifespan for Williams patients is shorter than average due to the complications from these medical problems, but not from the Syndrome itself.

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Williams patients usually have vocabularies larger than expected for their mental age and tend to be more expressive than normal children. However, they typically do poorly on tasks involving visual processing such as coloring and copying drawings. The brain anatomy of Williams syndrome patients is normal, but the total volume is slightly reduced. The areas that seem to be unaffected include the frontal lobes and a part of the cerebellum called the neocerebellum, as well as parts of the temporal lobes known as the limbic area, and the primary auditory area.

Study of this syndrome has shown that low IQ scores can indeed cover the existence of other skills and capacities. And it thus serves as an example that other so-called mentally disabled individuals could have lots of potential waiting to be discovered if only researchers and society take the time to look for and nuture them.

References:

Hemizygosity at the Elastin Locus in a Developmental Disorder: Williams Syndrome. A.K. Ewart et al. in Nature Genetics, Vol. 5, No. 1, pages 11-16; September 1993.

http://children.webmd.com/williams-syndrome-11011

DNA Computing

There are limits to desktop and supercomputers as eventually there will come a point when electronic miniaturization can go no further as components become smaller and more transistors are embedded onto silicon chips. DNA computing is just one of many new computing techniques already in development. Because DNA is so ubiquitous, it is convenient as well; the four constituent bases  of DNA act as “bits” of information comparable to 0 and 1 in binary.

First demonstrated in principle in 1994, DNA techniques were used to solve a Hamiltonian directed-path graph, an important type of problem in mathematics and computer science.  Those who haven’t heard of this problem need only to think back to elementary school, where teachers might have presented a puzzle challenge to draw a continuous set of lines through several points on paper without retracing any lines.  The logic behind this is that any solution attempts are carried out simultaneously, breaking down larger problems into smaller ones, which can then be solved at the same time.

In the initial demonstrations, each point on the was represented as a 20-unit oligonucleotide (a short segment of the DNA molecule), and allowed moves between any two points were represented as 10 unit complements. Whenever a grand total of oligonucleotides was linked to DNA polymerase (an enzyme that copies DNA), then all possible paths were produced.