Author Archives: emily lui

The worst endless cycle

Emma Bryce from Ted-Education explained why we itch, a common phenomenon that occurs to everyone. Although itching may not seem like a big deal, for people with skin diseases, it could become very irritating and painful. In order to target this issue, Emma described the itch-scratch cycle to give us a deeper understanding about itching.

We realize that we get random itching from time to time. So, what really causes itching? Our skin is evolutionarily built to feel the slightest of touch to alert us of harmful things that land on our skin. In our case, the danger that we encounter are things that irritate our skin. This includes bugs and allergens such as pollen and dust.

Skin sensitivity varies from person to person, and this is an important factor for skin diseases. For example, people with super sensitive skin can be prone to conditions like eczema, which is itching that turns into rashes. Another condition is psoriasis, which is an abnormally fast skin reproduction rate that piles up as dead skin, making the infected area look very patchy and scaly. These conditions lead to irritating consequences such as rashes, redness, and skin fissures, which is the skin cracking open. In severe cases, these could lead to bacterial infections.

Eczema, credit to flickr

The itching process occurs very fast. The trigger occurs when some irritant lands on the skin. The skin nerve endings detect it and shoot an itching signal from our spinal cord to our brain. Then, our brain alerts us that particular spot is itchy and our reaction is to scratch it. When we scratch, we are scraping against our skin and this induces a very low level of pain. Then, our nerve endings send pain signals via the same route as the itching signal to our brain. Since only one type of signal can be transmitted per path, the pain signals override the itching signals.

Scratching, credit to flickr

As this happens, our brain tries to relieve the pain by producing a neurotransmitter, which is a chemical messenger that helps neurons send signals to specific cells. In our case, the neurotransmitter is serotonin, and it is overriding pain signals with itching signals. For this reason, we end up feeling itchy again after scratching. This whole process is known as the itch-scratch cycle.

Personally, I have mild eczema and I easily get rashes and redness on my skin. I can definitely relate to the itch-scratch cycle and how irritating it could be. Hopefully, scientists will find a way to disrupt this cycle and find a cure for all these terrible skin conditions.

-Emily Lui

The ultimate stress-reliever

Scientists at Princeton University discovered that exercising stimulates the growth of new brain cells that makes us relaxed. However, this only occurs after three to six weeks of working out. Therefore, we must keep exercising to trigger these positive biochemical changes.

People always knew that exercising is beneficial in many ways, such as improving moods, boosting confidence, and preventing some diseases. But, no one explained this phenomenon scientifically. Thanks to researchers at the University of Colorado Boulder who picked up on what their fellow scientists at Princeton University discovered, these researchers learned that exercising remodels the brain. With exercising, the brain does not need to express a certain neurotransmitter to make us less anxious upon stressful conditions.

Neurotransmitters are chemical messengers that help brain cells send signals to specific cells. One type of neurotransmitter is serotonin, it relieves us when the brain feels like the body is overstressed. The researchers at University of Colorado Boulder decided to target serotonin to see how exercising affects its activity. To do so, they conducted an experiment on rats.

Serotonin maintains mood balance, credit to Flickr

In the experiment, the rats who did not exercise was the control group and the rats who exercised for a few weeks was the experimental group. Both groups were exposed to a stressful stimuli and results showed that control group expressed more serotonin and rats who exercised had minimal serotonin activity. Therefore, this explains how exercising causes people to be less stressed despite facing tough situations, where serotonin is not needed to counter the stress.

Anxiety and stress can lead to oxidative stress, which is the overproduction of harmful free radicals in our body. Free radicals are chemical species that have unpaired electrons. This makes them highly reactive and can lead to cell death if they wrongly react with chemicals that are essential for life. While exercising, our body creates chemicals called antioxidants to counteract these free radicals by donating its electrons.

Oxidative Stress can lead to terrible consequences, credit to Flickr

In an experiment conducted on rats, there were two groups; those who exercised and those who did not. Then, both groups were exposed to an artificial chemical that induced anxiety. Unsurprisingly, the group of rats who exercised were unaffected by the chemical at all.

Exercising does wonders by improving both our physical and mental health at the same time. All we need to do is implement a bit of physical activity into our daily routine and we will feel the effects within a few weeks. From a young child to an elderly, the benefits of exercising do not discriminate. So, what are we waiting for? We should all stop whatever we’re doing right now and go for a run!

-Emily Lui

To drink, or not to drink?

Alcohol is widely consumed among cultures such that each culture has its own alcohol beverage. Despite the unlimited selections of alcohol, all of them lead people to the same fate; the major hangovers after excess alcohol consumption.

Every culture has unique alcoholic beverages. For example, in southeast Asia, venomous snakes are infused in rice wine to make snake wine, credit to flickr

Dr. Erik Hefti of University at Buffalo listed the common over the counter (OTC) medications people used for treating hangovers and focused on the efficacy of each. However, many products lacked evidence that they provided hangover relief at all. Therefore, the best hangover remedy is to either quit drinking alcohol or consume less while remaining hydrated.

Ethanol, the main ingredient in alcoholic beverages, causes hangovers. Ethanol dehydrates the body because its chemical properties force us to produce excess urine, thereby draining our water content. Additionally, the body metabolizes ethanol into a toxic by-product called acetaldehyde, which is harmful and causes minor inflammation. This disastrous combination leads to hangovers, with symptoms such as nausea, dry mouth, irritated eyes, and headaches.

Ethanol metabolism, credit to National Institute on Alcohol Abuse and Alcoholism.

Dr. Hefti debunks myths regarding products that cure hangovers, such as N-acetylcysteine (NAC) and vitamins. NAC is helpful because it enhances antioxidant production, which speeds up ethanol metabolism. Despite the benefits, it does not remedy hangovers. Furthermore, alcohol only impacts the body’s vitamin levels over a prolonged period of consumption, so, vitamins cannot treat acute hangovers. Therefore, people who claimed these products were effective most likely experienced the placebo effect, since there is no scientific evidence behind their claims.

Ineffective hangover remedies are a pain in the butt, so what relieves hangovers? The answer is nonsteroidal anti-inflammatory drugs (NSAIDs), which includes Aspirin and Ibuprofen. These drugs are perfect for hangovers because they target headaches, pain, and inflammation. But, over relying on NSAIDs may cause side effects such as nausea, abdominal pain, and gastritis. Therefore, prolonged use of these drugs is not an ideal solution.

For some people, alcohol is a coping mechanism for stress and misery. For others, they think drinking is fun. However, alcohol is still harmful to the body and people should not turn to it as a remedy or recreational activity. There are many constructive methods to deal with mental health issues, have fun, and live a healthy life. So, why suffer the consequences when one can opt for better alternatives?

-Emily Lui