Tag Archives: chemistry

Your Brain in Love

Have you ever rejected someone who was madly in love with you? Have you ever been rejected by someone you really loved?

Neuroscientist, Helen Fisher, asked these two questions 20 years ago, both to which 95% of men and women said yes. Determined to understand this magic, she began a multipart project in 1996 to investigate the neurochemistry involved in romantic love.

She studied couples who had just fallen madly in love with each other, individuals who were dumped by their partners that day (talk about a rough day, huh), and couples who have been married for 20+ years. The fMRI scans revealed that people in love show brain activity in the same regions, the nucleus accumbens and the ventral tegmental area (VTA), as those addicted to hard drugs such as opioids and cocaine. Both of these areas are associated with dopamine production and distribution. Dopamine is a neurotransmitter (chemical messenger) associated with the brain’s reward system, primarily involved in addiction, cravings, energy, and motivation.

Brain areas associated with dopamine.             Source: Wikimedia

Dopamine. Source: self

Essentially, this means that lovers and drug addicts show similar behaviour. I think that perhaps romantic love is an even stronger addiction in a sense that everyone experiences it at some point but the same can’t be said for other addictions such as substance abuse or gambling. Those in love show the same fundamental symptoms of addiction: craving, tolerance, emotional dependence and when they get dumped they experience withdrawal and relapse.

Another neurotransmitter involved, according to Fisher, is serotonin which regulates mood, anxiety, and depression. Interestingly, she found that new lovers and long-term lovers had the same basic reward systems, with one exception. The fMRI scans showed that new couple had more activity in brain regions linked with anxiety; whereas long term couples showed activity is regions associated with calmness and pain suppression.

Serotonin. Source: self

With 20 years of research on the brain in love, Helen Fisher is a household name in Neuroscience. She nicely summarises her major findings over the years in this TedTalk. Dating platforms such as Match. com, Tinder, and others use her research on what attracts people to each other in their algorithms.

I think love as a positive addiction is certainly an interesting perspective. I believe that the scope of this can go far beyond just algorithms. Perhaps this means that building strong and healthy relationships can help people recovering from addictive behaviours such as substance dependence, binge eating disorders, gambling, etc. by acting as a reward replacement. Additionally, with rising divorce rates cross-culturally, understanding the mechanisms involved in love and how we form relationships, can help us become more empathetic and build long-term relationships as a society.

 

A Search for Cleaner Water

Photo taken from Flickr Commons. Increasing demand for clean drinking water to drink.

As the Earth’s population grows, there is a parallel increase in demand for clean, potable water.

The ability to effectively and efficiently filter water is a problem that many researchers and scientists are trying to solve. Water clean enough for human consumption is free of undesirable chemicals, biological contaminants, and harmful gasses.

To address this growing issue, researchers have been exploring the applications of carbon nanotubes. Analogous to aquaporins, proteins in cells that transport water, these nanotubes are synthetically created to have a higher efficiency of water transport and selectivity for ions and molecules.

Aquaporins: Biological water transporter located in the cell membrane. What researchers are trying to replicate.

The structural feature responsible for the successful transport of water in aquaporins is the narrow, hydrophobic (water fearing) channel which forces water to translocate in a single-file arrangement. Past studies have tried to mimic this structure using a >1 nm diameter, but failed to replicate the effectiveness of aquaporins.

However, new studies done by Tunuguntla et al.  have proven that it is possible to create artificial water channels with increased productivity to the natural protein translocator. They have created carbon nanotubes with diameters approximately 0.8 nm wide. The new nanotube models showed water flux at a rate 6 times higher than aquaporins.

In addition, their experimentation showed a very high ion selectivity. In solutions with a very high salt concentration (NaCl), the nanotubes were still able to transport water. This finding is very promising for the desalination of water. In areas were fresh water is unavailable, application of carbon nanotubes in water purification systems would prove immensely beneficial to communities facing water scarcity.

These findings are especially promising because scientists have created an artificial water channel that rivals biological equivalent.

-Mya Dodd