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A Glass of Wine a Day Keeps the Doctor Away?

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Since the 1990’s scientists have wondered whether red wine has any potential health benefits for the average consumer. Studies have shown that a polyphenol known as resveratrol in the wine does help to reduce the risk of cardiovascular diseases, in particular atherosclerosis.

How did scientists know in the first place that red wine could potentially help? It all has to do with the French Paradox. The French paradox looks at how the French have a lower risk of cardiovascular diseases despite consuming a diet that consists mainly of fats. What’s the main difference in these diets from others around the world? They drink a lot of wine.

Studies looking into red wine discovered a polyphenol known as resveratrol. Resveratrol comes from the grapes that make the wine. It was noticed due to its anti-oxidant and anti-inflammatory properties. Scientists believed that this may have something to do with the health benefits of the wine.

Resveratrol was first tested on mice models by feeding them resveratrol supplements and in the end it showed a decrease in the risk of cardiovascular diseases, specifically atherosclerosis. Atherosclerosis is when the arteries harden and narrow making it difficult for blood to flow through the body. The question scientists then wondered was how exactly did resveratrol help with this?

Some ways resveratrol helped is by increasing the amount of high density lipoprotein cholesterol, also known as the ‘good’ cholesterol in our body as well as decreasing platelet aggregation. This coupled with its antioxidant abilities made resveratrol a very helpful polyphenol in red wine.

Benefits of Red Wine (From :Saleem, T. S. M. & Basha, S. D. (2010). Red wine: A drink to your heart. J Cardiovasc Dis Res., 1(4), 171-176.)

The research was more recently extended to human trials and similar results were found as was with the mice. However, to this day doctors are hesitant to encourage patients to drink as the consequences from drinking alcohol are too high for the benefits of resveratrol. Non-alcoholic red wine is available with all the benefits of the polyphenol without the worry of the alcohol.

The idea that red wine can help with our health is interesting, however I believe that the risk of alcohol is too great. You can never be sure how much wine is too much and it varies from person to person. To be on the safe side I would recommend other forms of resveratrol supplements other than red wine to help with any cardiovascular problems. However, it is great to know that drinking red wine isn’t all that bad. Thus in conclusion, the polyphenol resveratrol does help to reduce our risk of cardiovascular diseases, so a glass of wine a day, does keep the doctor away!

~Sajni Shah

 

References:

Chiva-Blanch, G., Arranz, S., Lamuela-Raventos, R. M., & Estruch, R. (2013). Effects of Wine, Alcohol and Polyphenols on Cardiovascular Disease Risk Factors: Evidences from Human Studies. Alcohol and Alcoholism, 48(3), 270-277.

Gilford, J. M., & Pezutto, J. M. (2011). Wine and Health: A Review. American Journal of Enology and Viticulture, 62(4), 471-486.

O’Keefe, J. H., Bhatti, S. K., Bajwa, A., Dinicolantonio, J. J., & Lavie, C. J. (2014). Alcohol and Cardiovascular Health: The Dose Makes the Poison…or the Remedy. Mayo Clinic Proceedings, 89(3), 382-393.

Smoliga, J. M., Baur, J. A., & Hausenblas, H. A. (2011). Resveratrol and health – A comprehensive review of human clinical trials. Molecular Nutrition & Food Research Mol. Nutr. Food Res., 55(8), 1129-1141.

Saleem, T. S. M. & Basha, S. D. (2010). Red wine: A drink to your heart. J Cardiovasc Dis Res., 1(4), 171-176.