Category Archives: New and innovative science

Shaking up what we knew about shaken baby syndrome

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Keeping infants safe is important.

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But is shaking as harmful as it is made out to be?

When infants arrive in emergency with spinal injuries and bleeding in the brain, doctors are often quick to point the finger at the caregiver. Recently more and more evidence supports mechanisms other than shaken baby syndrome as the cause of such injuries in infants.

The cover story of The New York Times Magazine from Feb 2 2011 explores the issue and the implications for people who have been charged under these circumstances.

NYTMag cover

New York Times Magazine cover image

When caregivers are on trial for child abuse, lawyers use doctors to testify how the injuries of the child were inflicted. More and more doctors are testifying for the defense and in turn exposing the prosecution doctors to the validity of these alternative explanations (such as infant stroke caused by and infection).

This article is not discounting shaken baby syndrome as a real problem, but claims that some people have been wrongly accused because the diagnosis was made too hastily.

Some important issues are brought up regarding the use of science in the courtroom.

First of all doctors can be paid for their testimony. I think the outcome should not be reflective of the doctor the accused can afford. When monetary value is placed on the information presented in the courtroom the facts given to the jury can be skewed. Even worse the picture of scientific knowledge presented is not limited to the courtroom; news and media coverage of high profile cases will pass biased scientific information on to the rest of the world.

A particularly relevant point is that jurors may have difficulty understanding the science presented to them, and this can hinder their ability to properly decide on a verdict. What we learn in Scie 300 can have significant impacts on how effectively science is used in the courtroom.

This issue also points out a flaw in the scientific method; conventionally scientists come up with hypotheses which then raise new questions to be tested. Unfortunately when dealing with the law, a hypothesis that is rejected years after it was formulated can have a major impact on those who were wrongfully accused according to the knowledge at the time. Here we have a tradeoff between putting innocent people away and letting a child abuser continue putting children in harms way.

The bottom line still is: never shake a baby.

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Cloning the Mammoth: It’s Big!

Will mammoths once again walk the earth? Photo - Flickr: Tracy O

Personally, when anyone talks about mammoths, which isn’t actually very often, I immediately think of Manny, the grumpy, but loveable, mammoth from Ice Age. However, Manny may soon be the second most well known mammoth around. Last month the headline: “Mammoth ‘could be reborn in four years’” was published in the British newspaper The Telegraph. Akira Iritani, a professor at Kyoto University, believes that we now have the technology to resurrect the giant mammal, and he wants to make it happen.

Until recently, cloning from frozen specimens was thought to be impossible. Ice crystals formed in the cell during freezing cause extensive damage, rendering cells unviable. However, in 2008, Dr. Teruhiko Wakayama and his team successfully cloned a mouse using mice that had been frozen for sixteen years. The trick was that they didn’t use whole cells, instead they searched for intact nuclei that hadn’t been damaged during freezing. The intact nuclei were inserted into mouse cells, from which the DNA had been removed, and implanted into a surrogate mother.

Cloning the mammoth could require as little as a few grams of soft-tissue from a frozen mammoth. Iritani plans to look for a specimen in the permafrost of Siberia this summer. After finding the tissue and isolating the viable nuclei, researchers will insert the nuclei into the egg of an African elephant and she will act as the surrogate mother for a gestation period of close to 600 days.

Cloning the mammoth would be an amazing scientific breakthrough, but this kind of science raises many concerns and I can’t help but wonder: Why we’re doing it?

In 2008, in the Guardian, Bill Holt, head of reproductive biology at the Zoological Society of London, raised the following concern: “You have to think about why you would do it and where you would put it”. Planet earth has changed drastically since the mammoth disappeared at the end of the last ice age. So I have to ask: Where will the new mammoth live? Will we clone more than one? Will they reproduce? If so, they will have a very small gene pool.

Given the limited number of viable nuclei, it seems unlikely to me that we will be able to bring the mammoth back for good. Even if we did, they would never be able to live free in the wild. So, as incredible as it would be to see a live wooly mammoth face to face, it seems counterproductive to bring back the mammoth when many other species on earth are also facing extinction. Why not spend our energy saving species that are still here, rather than trying to bring them back once their gone?

The Fifth Dimension

An article posted in the Technology and Science section of msnbc.com indicates that physicists are currently trying to discover the fifth (and even the sixth, seventh, or eighth) dimension with new breakthrough technologies.

It has been claimed that there are four dimensions – the three spatial dimensions and the fourth one being time. However, physicists claim that there are more dimensions that make up our universe. The two leading physicists that support this theory are Lisa Randall from Harvard University and Raman Sundrum from John Hopkins University. Randall and Sundrum’s theories help provide explanations for some of the most profound scientific dilemmas since Einstein’s time.

The lightness of gravity

The weakness of gravity was always a mystery to physicists. In Randall’s book called Warped Passages, she states, “A tiny magnet can lift a paper clip, even though all the mass of the earth is pulling it in the opposite direction.”

By having more dimensions, string theorists – physicists that believe that the building blocks of all the matter in the universe are string-like particles vibrating with their own frequencies – can create formulas and equations that could explain the weakness of gravity.

Smashing particles

With new technology like a new underground particle accelerator, new dimensions could be discovered. New dimensions are hard to detect due to our inability to see them – our human eyes can only perceive the three spatial dimensions. The underground particle accelerator would be able to show the new dimension – the evidence would be a new class of particles that had the same charge as the normal particles but with extra mass. This extra mass indicates that the particles gained extra momentum that propelled them into the fifth dimension.

It seems like in the immediate future, the fifth, sixth or even the eleventh dimension could be discovered. The physics that we come to learn today might be obsolete and so it seems like those science fiction books that people read might be true after all!

Aerobic Exercise Boosts Memory

As midterms are quickly approaching, many of us are trying to retain and cram as much information as we can into our brains. If it hasn’t already become apparent, most of us will realize that our brains can only store a limited amount of information. Fortunately, there appears to be a way to expand and boost our memory, and that is simply through aerobic exercises.

Image from: www.runningrules.com

In a recent article published by Science News (which can be found here), they reported a study that was highlighted in the Proceedings of the National Academy of Sciences. In this study, scientists discovered that adults who frequently performed aerobic exercise activities such as walking developed an increase in hippocampus volume. The hippocampus, which is a memory centre in the brain, normally decreases in size with age, however in the study the reversed occurred. They also found that the members had higher levels of Brain-derived neurotrophic factor (BDNF), which is a brain-aiding molecule.

Image from: www.library.thinkquest.org

Wikipedia article on the hippocampus: http://en.wikipedia.org/wiki/Hippocampus

Wikipedia article on Brain-derived neurotrophic factor (BDNF): http://en.wikipedia.org/wiki/BDNF

The study compared two different groups of adults aged 60 to 80. In one group, the adults did toning workouts such as weight training and yoga sessions for a year. While in the other group, the adults consistenly walked for three times a week. After a year, the group which simply did toning showed normal results, which consisted of some of the test subjects observing a decrease in hippocampus volume. On the other hand, the group that did a year of aerobic exercises observed roughly a 2 percent increase in anterior hippocampus volume.

If adults aged 60 to 80 can develop increases in the hippocampus by up to 2 percent, it begs the question of whether a younger study group would develop an even larger increase in their hippocampus. Hence, this study should be expanded to include a more diverse age group. Furthermore, why should the study stop there? They could also include teenagers, children, and possibly toddlers as well. Perhaps they might discover that people that have superior memory got that way by doing a lot of aerobic exercise during their childhood. It would also be interesting to understand why and how this process occurs. This is definitely a fascinating area of research, and it has great implications. It shows that exercise not only benefits the body, but the brain as well. So it is in everyone’s interest to maintain a healthy lifestyle and to keep fit.