Good Science! Bad Science?

Scientific literacy is a big part of science education; the ability to recognize pseudoscientific beliefs from scientific facts and theories is essential for science students. photo credits: openparachute.wordpress.com

In an attempt to retrieve interesting blogging topics, I spent part of my weekend scouting through scientific magazines (mostly on-line but also in prints). And it was awful.

First try, I found a newspaper article describing a link between global warming and skin cancer. According to this article, since global warming increases the earth’s average temperature, it affects the cloud formation at the poles, which in turn interacts with the ozone layer and increases the size of the ozone hole, which allows more UV radiation and may explain the increase cases in skin cancer reported in the US and Europe. For a while, I searched for the sources they cited, but to no avail. It turns out, they were citing from a draft from WMO (World Meteorological Organization) that is not yet released to the public. Thus, there wasn’t a way to verify the information. In addition, the author’s name was not specified.

In retrospect, this article can be easily identified as BAD SCIENCE. However, in the mist of my excitement on that tired bus ride home, the science sounded great. I even convinced myself that I to buy more sunscreen for this summer (to prevent damage from the extra UV rays). My point is, scientific babbles can appear anywhere and everywhere and at a time when we are least expecting.

Identifying GOOD SCIENCE

According to the library resources available here, and through our course blog, we can evaluate our readings using AACCOP.

A-   AUTHOR or SOURCE

A responsible scientist will stand behind him/her article, and be backed by a notable organization.

A-   ACCURACY

Good science is always falsifiable. Find the source of the information, and verify it for yourself.

C –CURRENCY

Science is always advancing; what was true ten years ago might now be obsolete.

C –COVERAGE

Is the research completed or only in progress? A hypothesis may only be a “guess” until the final conclusion.

O –OBJECTIVITY

Sometimes enthusiasm can cloud one’s good judgement. A scientist should present the research with disinterestedness.

P  -PURPOSE

Could there be a hidden agenda? Are the scientist hired by a neutral party? Or by the pharmaceutical companies themselves?

Lastly, just remember, we should always approach findings with a healthy dose of curiosity and skepticism. Good luck for everyone doing research!

Alzheimer’s Disease

A recent clinical trial on the hit show “Grey’s Anatomy” that was being conducted to find the cure to Alzheimer’s inspired me to write this blog post because I really don’t know much about this disease other than the fact that patients diagnosed with Alzheimer’s suffer from dementia and therefore, wanted to know more about the causes of this disease.

Alzheimer’s is a “progressive and degenerative disease” and is the most common form of dementia. The name for this disease comes from the doctor who first identified the disease: Dr. Alois Alzheimer. According to his research there are two main features to this disease: Plaques and Tangles

Plaques are made of a protein already consisting within the brain called A-beta. A patient with Alzheimer’s generally has more of this protein that accumulates in the brain. They accumulate in such high numbers that it makes it difficult for the enzymes in the brain whose job is to get rid of this protein overwhelming the whole system. Over time as they accumulate they condense into plaques that are toxic.  Researchers believe that these A-beta proteins somehow change the genetic code of the tau protein thereby promoting development of “Tangles”.

Tangles as mentioned before are made of tau protein. These are located in the nerve cells and perform key duties such as self-repair of the nervous system as well as maintaining a transport system within the nerve cells. However after these are modified by the A-beta protein they tend to pile up and create tangles. By creating these tangles the transport system of the cells is disrupted and therefore the cell dies.

The toxic plaques along with the tangles leads to the slow degeneration of cells in the brain, thereby causing the brain to shrink as seen in the following picture.

"Normal Aged brain vs Alzheimer's patient"

I hope to look into more research that has been done on the purpose of the A-beta protein as well as other further research into how doctors might proceed to deal with this disease in the future. Until then I will direct you to the following link that has more information on Alzheimer’s Disease.

http://www.alzheimer.ca/english/

To boldly go ever after? The search for habitable planets.

Have you ever dreamed of exploring outer space? Of reaching up into the stars to venture where no person has gone before, exploring strange and exotic worlds all the while saving mankind from imminent destruction? From Star Wars to Battlestar Galactica the imaginative world of science fiction has painted a picture of the galaxy quite dissimilar from our own. Theirs is a universe filled with habitable-world’s innumerable star systems surrounded by small rocky planets. While this makes for compelling story-lines, until recently it was thought that this view couldn’t be farther from the truth.

Earlier this month it was released that NASA’s Kepler Mission, named in honour of German astronomer Johannes Kepler whose work laid the foundations for the laws of planetary motion, had discovered its first so-called Goldilock’s planets. A Goldilock’s planet is a terrestrial (rocky) planet of a similar size to Earth in an area known as the Circumstellar Habitable Zone. A system’s CHZ is a spherical region of space surrounding a star where a planet could theoretically possess the life’s essential element, water. In this zone, planets receive enough solar radiation to keep the bulk of the water above freeing, but not so much as to boil. In addition to being in the CHZ a Goldilock’s planet must also be within a region known as the Galactic Habitable Zone (GHZ). Along the same lines as the CHZ the GHZ is a region of the galaxy where it is thought that there is the highest possibility of finding habitable planets. It is far enough away from the galactic core as to not be severely affected by the high-energy radiation common there, but not too far as to be devoid of the heavier elements essential for the formation of terrestrial planets. In the Milky Way this regions starts at around 25,000 lights years from the galactic core and extends to about 32, 000 ly.

While the candidate planets discovered by the Kepler Mission will require careful follow-up to determine if they are indeed Earth-like planets, preliminary observations suggest that five of the fifty-four planet candidates in the CHZ are indeed terrestrial, and similar in size to our own. A new device from the Harvard-Smithsonian Centre for Astrophysics will likely play a key-role in verifying the characteristics of these new worlds. Knows as the High-Accuracy Radial velocity Planet Searcher or HARPS-North for short, the instrument soon to be installed in the Canary Islands will enable researchers to measure the tiny radial-velocity signal produced by small planets like the Earth. This data allows researchers to determine the densities of the target-planets enabling them to distinguish terrestrial worlds from their more common gas-based brethren.

While these five planets represent a tiny fraction of the over 1200 planet-candidates found thus far during the analysis of over 150,000 star systems discovered by the Kepler Mission, that they were all located in such a minuscule fraction of the galaxy suggests that a universe of boundless habitable-worlds might not be too outside the realm of possibilities.

References Cited:

  1. NASA (2011, February 2). NASA finds Earth-size planet candidates in habitable zone, six planet systemScienceDaily. Retrieved February 16, 2011, from http://www.sciencedaily.com­/releases/2011/02/110202133321.htm
  2. ANI. (2011, 2011-02-15). New device to help confirm kepler’s planetary candidates. The Wall Street Journal,
  3. Mori. (2007). Fermi , what paradox? (image credit). Retrieved 02/15, 2011, from http://forgetomori.com/2007/ufos/fermi-what-paradox/

I found this article on the illegal trafficking of kidney organs to be very interesting, since in 2010 about 88,000 individuals required a kidney transplant.

The article begins with an elaborate and engaging story about a man from Athens, Greece traveling to Delhi, India in order to save his life by receiving a kidney transplant. The story continues by explaining how the man ended up in what basically was a kidney hospital/hotel, with entertainment for patients for the duration of their stay. He was initially on dialysis until the operation eventually got scheduled. If you have kept up with the show ‘Desperate Housewives’, you would know that one of Susan Delfino’s kidneys had to be removed due to a trampling incident that caused her kidneys to burst, and she too had to go on dialysis.

The kidney is a vital organ that allows us to filter out the excess water and toxins from our blood. When the kidney fails, often from the result of other problems such as diabetes and high blood pressure, western medicine suggests a treatment method called dialysis. Dialysis allows the blood to go through a cleansing process at least three times a week. The treatment includes side effects such as itching, fatigue, and risk of infection.

The article continues by explaining that the head surgeon, Amit Kumar who doesn’t have a formal training degree in western medicine, built the worlds largest kidney trafficking rings. His clients come from Greece, Turkey, the Middle East, Canada and the US. According to CBI investigator Rajiv Dwivedi, Kumar is India’s foremost kidney surgeon. He has made so much money that he has been able to finance Bollywood movies and fend off extortion threats from the Mumbai mafia.

I have very conflicting feelings about this article. I don’t know whether to feel happy that people in need are getting kidneys, or to feel upset about the corruption in India. The article went on about Kumar’s trial in court and how there was not sufficient evidence to detain him longer. It was interesting to learn about the politics of scientific practices, and I feel that the health care system needs to be more efficient in order to provide this service openly rather than through underground organ trafficking.