Category Archives: Science in the News

Gluten-freedom?

   Image: jefferyyw  Image from flicker by jefferyw

     Diet trends come and go. (Anyone remember the Atkins’s diet?) The newest fad that has seemed to appear is the gluten-free lifestyle, claiming to help you lose weight, increase energy, and decrease that bloated feeling. However, there have been increasing cases of gluten sensitivity that have emerged  due to various external factors. So is gluten sensitivity really becoming more common? Or is being gluten-free another diet fad?

Gluten is a protein found in wheat, barley, and rye. It is what gives our breads the texture we love. It gives pizza dough its stretchy consistency. It gives soups and stews viscosity.

However, gluten proves problematic for people with celiac disease, which affects around 1 in 133 Canadians.  Celiac disease is a disorder where a person is not able to digest gluten protein as the body sees it as an invader and attacks it with antibodies and at the same time injuring the small intestine. This damage causes nutrients not be absorbed properly through the villi in the intestine, consequently causing the individual to be malnourished and feel sickly. Other symptoms include fatigue, skin problems, and even depression.

Brown, from the John A. Burns School of Medicine at the University of Hawaii, believes that gluten sensitivity is emerging as a separate condition from celiac disease. The increase in cases of gluten intolerance may involve plant genetic modifications, gluten as a food additive, environmental toxins, and human genetics.

Gluten intolerance is now starting to be seen as a spectrum where at one end is celiac disease, and at the other end is a person who seems to be digesting gluten fine. However, gluten is generally a protein that is not easily digested by humans. Everyone has a limit to the amount of gluten that the body will digest with ease.

People with even just a low level of gluten sensitivity may live a gluten-free lifestyle simply because it makes them feel better. However, switching to gluten-free is not an easy step and requires planning. Although gluten-free foods are now easier to find at your local grocery store, they are not necessarily healthy. Many of these pre-packaged foods are loaded with extra sugar or fat in order to make the food taste better. So skip the gluten-free brownies.  A gluten-free diet is only a healthy one if you consume adequate fruits and vegetables, lean high quality meats, and substitute your usual carbohydrates with rice and grain-like crops like quinoa.

Gluten sensitivity has been found to be more common than it has been previously, especially affecting those with an eastern European background. Along with this increase has been a rising trend in individuals who choose to eat foods without gluten even though they do not need to, and claim to feel much better living that lifestyle. Ultimately,eating gluten-free is not a dangerous fad diet, but  is rather a very healthy lifestyle if done properly.

First Earth-like planet in habitable zone discovered by NASA Kepler team

Earth is one unique planet among the rest of the planets scattering across the universe. It is the only known planet which liquid water is abundant and numerous living organisms inhabit. However, Earth may no longer be as unique as we think it is.

The Kepler mission‘s science team has found a planet that is similar to Earth which locates in the “habitable zone” of its solar system. A habitable zone is a region around a sun where water can maintain its liquid state on a planet with sufficient atmospheric pressure. 600 light years from Earth, Kepler-22b, a planet which orbits in Kepler-22 system, has a radius 2.4 times the radius of Earth and an orbit period about 290 days. Its star, Kepler-22, is slightly smaller and cooler than our Sun. The composition of Kepler-22b is not yet determined by the Kepler Science team. However, judging from the size of Kepler-22b, the team estimated that the composition of Kepler-22b is most likely to be similar to earth composition with abundant amount of water.

(Artist’s concept of Kepler-22b from Kepler: Home Page)

How did Kepler science team find Kepler-22b which is 600 light years from Earth? The science team used Kepler telescope, which can monitors the slight decrease in brightness of stars when a planet orbits across the star. Kepler telescope can detect the change in brightness up to one ten-thousandth difference. Based on the amount of brightness decreased, the team can determine the size of the planet. In order to confirm the change in the brightness of a star is caused by a planet orbiting across the star, the team has to find 3 dips of brightness. These dips are separated with a set period of time to confirm the orbital period of the planet.

Although Kepler-22b is the first confirmed Earth-like planet which orbits in the “habitable zone” of its system, there are total of 48 possible planet candidates that are being observed by the Kepler mission’s science team. There is little doubt that more Earth-like planets will be discovered by the Kepler mission. Perhaps, within these planet candidates, there may be life living on one of these Earth-like planets.

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References:

Media announcement of NASA’s Kepler mission’s science team on December 5th,2011:

https://www.youtube.com/watch?v=en5OObU0ryU

Article of discovery of Kepler from NASA website:

http://www.jpl.nasa.gov/news/news.cfm?release=2011-373

Kepler Mission: Home Page

http://kepler.nasa.gov/

Kelper-22b From NASA Kepler website:

http://kepler.nasa.gov/news/nasakeplernews/index.cfm?FuseAction=ShowNews&NewsID=165

Artist’s concept of Kepler-22b

http://kepler.nasa.gov/images/Kepler22bArtwork.jpg

 

How fireworks produce various colors in the sky?

 (Image from Daily Disney by Joe Penniston)

Have you ever wondered how fireworks produce various colors in the sky? It sounds easy to produce; however, there is a lot of physics and chemistry involved in making fireworks. Colors in fireworks are generated by pyrotechnic stars usually just called stars, and the stars generally require an oxidizing agent, fuel, binder (which holds pellets together), and color producing chemicals to produce color effects.

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            Video from YouTube: Basic compositions of fireworks

Color production in fireworks involves two main mechanisms Incandescence, and Luminescence.

Incandescence from fireworks

Incandescence is one of the processes by which fireworks emit light produced from heat.

•The light emitted through Incandescence is produced through extreme heat, which when applied to another chemical compound can cause a bright glow that changes colors (initially emitting infrared, then red, orange, yellow, and white light) as the temperature intensifies.   When the temperature of a firework is controlled, the glow of components, such as charcoal can be manipulated to be the desired color (temperature) at the proper time. Metals, such as aluminum, and titanium, burn very brightly, and are useful for increasing the temperature of the firework.

 Luminescence from Fireworks

Luminescence is light produced using energy sources other than heat.

• Sometimes luminescence is called “cold light”, because it can occur at room temperature and cooler temperatures, thus it is the low temperatures involved in the process of luminescence that gives fireworks cooler shades of light, emitting instead blue, and green.  Luminescence is produced when energy is absorbed by electrons resulting in the electrons going into an unstable state of excitement. As the energy is absorbed by the molecule, the electrons in the atoms rearrange from their lowest energy rate to a higher energy state. When the electron returns to a lower energy state the energy is released in the form of a photon (light). The energy of the photon determines its wavelength or color.

 

Visible light of different wavelengths is detected by our eyes as a range of colors. Of the light that we can see, red has the longest, and violet has the shortest wavelength.

Image from hueconsultingblogspot

 

Color producing compounds (Careful formulation is required)

To make fireworks colorful, various metal salts are added to the basic oxidizing agent fuel.

Image (list of fireworks metal salts) from allsparkfireworks blog

(If you would like to see some colorful fireworks, watch this video.) Thank you

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          Video from YouTube:London Fireworks 2012  presented by BBC.

References:

http://www.pyrouniverse.com/consumer/howtheywork.htm

http://answers.yourdictionary.com/science/how-do-fireworks-work.html

http://www.elmhurst.edu/~ksagarin/color/discussion3-F07.html

http://chemistry.about.com/od/fireworkspyrotechnics/a/fireworkcolors.htm

http://en.wikipedia.org/wiki/Fireworks

http://hueconsulting.blogspot.com/2010/07/how-fireworks-produce-color.html

2012 will be even longer than you thought

This year is special for many reasons.  One reason being that it has an extra day. But did you know that it will actually be 366 days plus one second longer? We have all heard of leap years, but have you heard of the leap second?

Prague Astronomical Clock. Photo from Flickr by simpologist

For about the past 1000 years, the rotation rate of the Earth has been slowing down. This has made our day of 24 hours, or 86 400 seconds, about 0.002 seconds longer.  Over the course of a year, this adds about 1 second.  Therefore, a second (the leap second) is added to the Coordinated Universal Time approximately every year.  This maintains its time within 0.9 seconds of the timescale of the rotation of the Earth, also known as Universal Time.  The rotation of the Earth can vary, which means that the leap second it not added at the same time every year, nor is it added every single year.  The last leap second was added in 2008, the next one will be added June 30th this year.

Controversy

The United Nations Headquarters in Geneva. Photo from Flickr by calistan

Thursday, January 19, 2012, a United Nations meeting was held on international telecommunications.  At this meeting a recommendation was supposed to be made to keep or abolish the leap second.  However, with the delegates not being able to come to a consensus, the subject was put on hold until 2015.

The United States is the main advocate for eliminating the leap second, concerned about the cost and the potential havoc it could wreak.  Satellite navigation systems rely on the precise synchronization of time for communications.  When the leap second is added, these communications could be disrupted. Computer networks could also have a hard time adding an extra second to their clock.  If the second is added inconsistently across the world, potential disasters could occur in air traffic, financial trading markets, and cell phone networks.

On the other hand, countries like Britain, China, and Canada want to keep the leap second.  They argue that in the 40 years that leap seconds have been added, there have been no problems or disasters.  The elimination of the leap second would stop our day from being in sync with the rotation of the Earth and the Sun.  Also, thousands of years from now it could be noon on the clock, but the sun indicates that it is dawn.  The advocates for the leap second propose that the elimination of the leap second could cause even more difficulties.  One hundred or so years down the line, a leap minute may have to be introduced and this could cause more problems than the leap second.

For now, we will continue to introduce the leap second every year or so.  With the rotation of the Earth and Sun always changing we do not know what the future holds.  Will we keep the leap second?  Only time will tell.

References:

http://www.bbc.co.uk/news/science-environment-15563170

http://www.nature.com.ezproxy.library.ubc.ca/news/2011/111108/full/479158a.html

http://www.nytimes.com/2012/01/19/science/to-keep-or-kill-lowly-leap-second-focus-of-world-debate.html?_r=2&ref=science

http://www.nytimes.com/2012/01/20/science/the-leap-seconds-reprieve.html?ref=science

http://iopscience.iop.org.ezproxy.library.ubc.ca/0026-1394/38/6/6/pdf/0026-1394_38_6_6.pdf

The FUTURE is here! Skin-cell Gun

skin-cell-gunThe skin is our body’s first protective barrier from germs and viruses. Every year, thousands of victims from major effects of skin burns survive but some die while waiting for the skin to fully recover.In the past, burns have been treated with skin grafts which take skin sections from uninjured parts of the patient’s body, or grow sheets of skin artificially, and graft them over the burn. During the recovery period, the exposed flesh gives a greater chance for harmful pathogens to invade the human body.

Professor Jorg C. Gerlach and colleagues of the Department of Surgery at the University of Pittsburg’s McGowan Institute for Regenerative Medicine have been working on a way to minimize the healing time for burn victims, so that the chance of infection is reduced. The concept was first introduced shown in 2008. The good news is that they devised a tool to cut recovery time drastically and save lives. This method is called the Skin-Cell Gun.

The Skin-cell Gun is more like an airbrush gun that holds healthy stem cells that were isolated from a burn victim’s healthy part of skin. Using the device, these healthy stem cells are sprayed onto the burned area of a patient’s body. The surprising thing is the next part which is the recovery time. Instead of a burn wound in the past that normally takes weeks or months to heal, the same wound can be cured a lot faster. Dr Gerlach said the device takes only an hour and a half in total.

At the moment the technique can only be used on second-degree burns, but Dr Gerlach hopes it will later be able to tackle third-degree burns as well.

This video contains scenes that some viewers may find disturbing. This clip will also air on National Geographic‘s Explorer: How to Build a Beating Heart. The skin cell gun is a wonderful work!
References:
Spray-on Skin Is a Reality:
“Skin cell gun” regenerates cells in days

The God Particle Under the Looking Glass

After many decades of searching, CERN– the European Organization for Nuclear Research- may have just caught their first glimpse of the Higgs Boson. Also known as the God Particle for its elusiveness and significance, the Higgs particle is one of the final pieces of the subatomic puzzle that physicists worldwide are trying to solve in order to fully-understand the laws of our Universe.

 YouTube Preview Image CERN’s official statement on the LHC’s recent results and plans of further testing. 13 Dec 2011

But what exactly is this particle, and how has it eluded us for so long? First, The Standard Model of Physics predicts that the origins of mass must come down to a large field- one which surrounds us and pulls on us to supply the known masses in the Universe. In order for such a field to exist, a particle must exist at its core to provide this property, which has been named the Higgs Boson after Dr. Peter Higgs: a theoretical physicist at Edinburgh University. Until December though, most information about this mysterious particle was presented as theory rather than measurable evidence.

It was then that CERN’s Large Hadron Collider (LHC)- the largest particle accelerator in the world- had found signs of a possible Higgs Boson. This was done by colliding two protons at near-light speeds to observe what new matter may be created; this same technique may also discover the sources of dark matter, dark energy, and even the evidence of extra dimensions among other wonders in the Universe. As stated by Sir Martin Rees, the current Astronomer Royal of Britain:

“The LHC will generate, in a microscopic region where beams of particles collide, a concentration of energy that has never been achieved before – a concentration that mimics, in microcosm, the conditions that prevailed in the universe during the first trillionth of a second after the big bang.”

After these protons were destroyed by this massive amount of energy created in the collision, large detectors scoured the site to detect whether any anomalies had occurred. Through these detectors, signal spikes arose in areas where it is deemed likely this Higgs Boson is located; however, there is still an estimated 1% chance that these fluctuations in December were caused by random events. As a result, previous plans to shut down the LHC until 2014 to increase power output have been disregarded, and testing will continue onward well into 2012 to ensure consistently in data. If the accelerator continues to run smoothly, CERN plans to have the God particle isolated by the end of the year. However, this deadline seems rather ambitious considering the LHC’s recent history of shutdowns, including causes from electrical issues, coolant leaks, animal interventions and helium leakages among others since 2008. The magnitude of the discovery further adds to the scepticism that the particle could be isolated so quickly. Nevertheless, the scientific community will wait patiently to hear the results of the world’s largest accelerator.

Dark matter and dark energy will have to wait, it seems.

References

http://www.guardian.co.uk/science/2011/dec/13/higgs-boson-lhc-explained?intcmp=239

http://www.popsci.com/science/article/2011-01/cern-decides-keep-lhc-running-through-2012-hoping-find-elusive-higgs-particle

http://www.popsci.com/science/article/2011-12/tantalizing-glimpse-no-definitive-higgs-sighting-yet-%E2%80%94-wait-2012

Will SAV001 Save Us from AIDS?

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Video from University of Ontario : Media Conference on FDA Approval for SAV001

Acquired immune deficiency syndrome, better known as AIDS, was introduced to human race only a few decades ago but has since become a worldwide problem. Our society faces an AIDS pandemic. Millions of lives were taken by the disease, and more are to be lost if nothing is done to help. Vigorous researches attempt to develop a better understanding of the disease and ways to fight it. Recently, Professor Chil-Yong Kang and his colleagues at the University of West Ontario announced that they have come up with SAV001, a promising vaccine for HIV, and was approved by the FDA to proceed to human testing. Although this is enlightening news, some remain skeptical as HIV vaccines did not turn out successful in the past.

To understand why HIV vaccines are so hard to design, one must understand the mechanisms of vaccines and the nature of the HIV virus.

Image from Wikipedia by Fvasconcellos : Lock and Key Mechanism of Antibody and Antigen

Vaccines promote production of antibodies by white blood cells. Antibodies physically attach to antigens, foreign, potentially harmful molecules, or cells infected by antigens. This allows the immune system to target the tagged cells and destroy them to prevent further spread and damage. Antibodies allow such high level of specificity by recognizing epitopes which are unique and characteristic parts of antigens. In short, vaccines  introduce harmless epitopes and the body produces antibodies which can be used if the real disease infects the individual later on.

 

 

Image from National Institute of Health : Mature and Immature HIV

The difficulty associated with designing an HIV vaccine is related to the fact that the epitope for this virus is very variable. There are many subtypes of HIV and a vaccine designed for specific one of them is not likely to be effective for another. The virus also has a high rate of mutation, meaning that it is possible for a virus that has been genetically modified to be harmless to mutate back to a harmful form. For such reasons previous HIV vaccine candidates either had low efficacy or actually increased the rate of infection in some of their subjects.

 

Dr. Kang explained that SAV001 works by infecting cells with HIV to produce more virus, collecting them, and purifying them with chemicals and radiation. The dead virus as a whole is injected to elicit antibody production and activation of associated immune responses. If all goes well, the vaccine may be commercialized within a few years.

Human testing consists of 3 phases where the vaccine is tested for its safety and efficacy. Phase I for SAV001 is to begin in January 2012. Will SAV001 turn out to be a success or leave us in another disappointment? Whatever the result may be research for AIDS prevention and cure must continue. It is not likely that SAV001 will be effective for all people and subtypes of the virus. And will it be accessible in terms of cost and availability for all the people who need it? Probably not. More work needs to be done to fully fight off the disease and the misery it brings throughout the world.

 

Further Reading :

http://www.vancouversun.com/health/Canadian+researchers+start+clinical+trials+vaccine+January/5887090/story.html

References :

http://communications.uwo.ca/media/hivvaccine/

http://en.wikipedia.org/wiki/Hiv_vaccine

http://www.fiercebiotech.com/topics/fda_approval_process.asp

A cure for the common…hangover?

        

Image from Flickr: silent(e)

Recent scientific investigations  have led to the findings of an ancient Chinese herb that is able to remove the painful effects that are known to follow the consumption of alcohol; a college student’s dream!  Yes, this chinese extract from the raisin tree Hovenia dulcis, has the sobering effects on a person after excessive drinking, can relieve the symptoms of a hangover and also may provide a lifetime cure for those suffering from alcoholism.   
 

Hovenia dulcis, Japanese Raisin Tree ; this tree may be the cure to problems involving alcohol. (Image on Flickr by Tie Guy II)

For years, many Chinese people have been  using this extract in their tea to reduce any uncomfort that is associated with a hangover. The compound from the ancient raisin tree that has been found as the source of the cure, is Dihydromyricetin (DHM). It has been recently studied  by Dr. Jing Liang of the University of California on lab rats (as mentioned in NewScientist).  The results included a quicker recovery from intoxication on the rats when they were given alcohol containing DHM (only 5 minute recovery time!), versus alcohol by itself (around  a 70 minute recovery time).  Liang also found through her research, that the addiction for rats that were constantly consuming alcohol began to decrease over time after given small doses of DHM weekly.  

 For the Future
The goal of this research, is ultimately to gain the ability to have it eventually be tested on humans.  Once this is achieved, the affects could be ground-breaking. As more alcoholics are “sobering-up”, they will more likely be able to keep a job and increase the economy.  It is also predicted that the safety of living may increase in regards to drunk driving.  With the help of this “new drug”, one could essentially have an evening of drinks and fun, and still be able to drive home after without being a drunken liability to themselves and others on the road.

But…
Ideally, all of the above outcomes would be true and the drug would be perfect.  However, humans as a race are unpredictable.  Personally, I do not agree that the drug will cure many people, and instead might cause people to drink more.  If there was no consequence of drinking (a hangover etc) then it would just be more appealing.  Other scientists like Marcus Heilig have also voiced their concern regarding the bad outcomes that may occur from use of the drug and whether or not it would be beneficial or harmful to the population. 

Image from Flickr by sfllaw

Dr Liang is on the path to something that could change the lives of many people.  With no side effects currently being seen on their studies thus far, let’s hope she gets approval to begin testing on humans in the near future.

 

 

References:

NewScientist article:
http://www.newscientist.com/article/dn21337-chinese-tree-extract-stops-rats-getting-drunk.html

Hovenia Duclis Journal:
https://www.thieme-connect.com/ejournals/pdf/plantamedica/doi/10.1055/s-0030-1249776.pdf

Link to Dr. Marcus Heilig:
http://www.niaaa.nih.gov/RESEARCHINFORMATION/INTRAMURALRESEARCH/ABOUTDICBR/LCTS/Pages/Chief.aspx

Dihydromyricetin blog:
http://alcoholreports.blogspot.com/2012/01/dihydromyricetin-as-novel-anti-alcohol.html