Category Archives: Biological Sciences

Solar Powered Sea Slug: Power of Photosynthesis!

We have learned that photosynthesis is an inherent characteristic of plants reserved for their survival by collection of sunlight as a means to their survival, but what would you say when there is an animal living on photosynthesis? Prepare to get your socks knocked off by what is about to come because this is an introduction to the sea slug literally living off the solar power.

Sea-Slug, Elysia chlorotica From Pedro Jorge Peu (pinterest)

Sea-Slug, Elysia chlorotica
From Pedro Jorge Peu (pinterest)

Photosynthesis is a process that generates sugar by absorbing the sunlight. More specifically, chloroplasts which are the food producers of the cell converts light energy of the sun into sugars that can be used by cells. It is a process thought to be reserved for the Kingdom of Plantae, eukaryotic, and multicellular organisms. Imagine a solar panel powering electricity to charge our cell phones; plants absorb their energy in a similar way too.

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Photosynthesis From Flickr Commons

Kingdom of Animalia on the other hand, derives from the Latin word Animalis literally meaning “having breath”, they are eukaryotic, multicellular, and do not survive relying on photosynthesis. However, in 2010, CBC news reported that in the case of the brilliant emerald green coloured sea slug Elysia chlorotica, it is not the case.

The photosynthesizing sea slug lives by the incorporation of chloroplasts within the cells which allows it to capture energy directly from sunlight as most plants do, through the process of photosynthesis. What was thought to be exclusive to plants is not the case due to the discovery of organisms such as E. Chlorotica. Generally speaking, it will have algae for its food supply, but if they are not readily available, these slugs will survive and function for up to nine or even ten months by the sugars produced through photosynthesis performed by their own chloroplasts.

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[Credit to FORA.tv]

In a study, it was found and proven that these slugs definitely have a way to support the survival of their chloroplasts. After the eight month period of its survival without readily available food source, “the majority of the chloroplasts within the slugs appeared to have remained intact and also maintaining their fine structure.” They do this by not spending their precious energy on activities involving finding food but staying intact synthesizing their own chloroplasts; ability acquired from yellow-green alga (Vaucheria Litorea). The studies are on-going for this slug as scientists are researching for its potential genes that could support chloroplast survival and photosynthesis.

Even after all this, they are still not truly photosynthetic organisms. Last year, Gregor Christa and his researchers reported that as E. Chlorotica can survive in dark environment which is why they still belong to the Kingdom Animalia. Animal or plant, it may be up to how the reader may decide. I decide on classifying this beauty as an animal true to its purpose; survival.

Grace Kim

Is that a new tortoise or an existing tortoise?

According to scientists, there are millions of organisms that have yet to be discovered. While many newly discovered organisms are insects, other organisms such as mammals, reptiles and birds are more rarely discovered. But, where do these undiscovered organisms live? Most of these unknown organisms may live at the bottom of ocean trenches or in remote parts of the world that have not been explored yet; however, can undiscovered organisms live among existing organisms that scientists have simply overlooked? Well simply, yes.

Map of Galapagos Island Source: Storpilot (Wikimedia Common)

Map of Galapagos Island
Source: Storpilot (Wikimedia Common)

The Galapagos Islands are a collection of islands that is home to many species of birds, land animals and sea creatures, most notably the finches that Charles Darwin observed. Additionally, the Santa Cruz Island, part of the Galapagos Islands, is home to two tortoise populations that live on the east (Cerro Fatal) and west (Reserva) ends of the island. For many years, scientists believed that the two populations were from the same tortoise species, but recent studies show that they are two distinct tortoise species. This is exciting because as previously stated, new species of organisms, other than insects, are rare; but when new species are discovered, a lot of new information can be gained from studying the unknown organism.

Tortoise Source: Chad Sparkes (Flickr Commons)

Tortoise
Source: Chad Sparkes (Flickr Commons)

Now, what are tortoises and how are they different from turtles? The definition for what constitutes a tortoise from a turtle differs depending on the country. Turtles and tortoises are a part of the Testudines order. In America, turtles are members of the order Testudines that live in freshwater and marine environments primarily. On the other hand, tortoises, by definition, live exclusively on land. Some morphological differences are that turtles have a streamlined shell and webbed feet to navigate marine environments, while tortoises have an arched shell and clubbed feet to help them survive on land.

Turtle Source: Michael Menefee (Flickr Commons)

Turtle
Source: Michael Menefee (Flickr Commons)

In their study, Nikos Poulakakis, Danielle L. Edwards and their team tested and compared the genes of the two tortoise populations located on the Eastern and Western parts of Santa Cruz Island that are believed to be one species, Chelonoidis porteri. To their surprise, the analysis revealed the two populations to be distinct from one another, thus creating a new species of tortoise for the Cerro Fatal tortoises, C. donfaustoi. Although many of the differences between the two species of tortoises are contained in DNA, the Reserva tortoises are on average, larger in body size, shell size and head opening than the Cerro Fatal tortoise.

As a result, new organisms can be found in many different places. Even organisms that were once believed to be a member of an existing species can become a new species as our technology and knowledge of different species increases. Who knows what new organism people will discover next?

Adrian Li

The Promising Near Future of Blood Transfusions

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Rendering of red blood cells. Source: Flickr Creative Commons – Nocturnal lust

Have you ever donated blood? Canadian Blood Services is always looking for more blood, because they need lots of it. For example, here’s a table of the required donations per single procedure.

Required amount of blood donors per case. Source: Canadian Blood Services – Who does my donation help?

As you can see, a single car crash can require blood from up to 50 donors. Such events can cause a shortage of blood. In fact, just last year, Canadian Blood Services issued an appeal for more blood donations, as blood supplies hit an all-time low, especially for type O universal donors.

What are universal donors? Donors of blood type O can donate to every other blood type, because they have no antigens (molecules that can cause severe and harmful responses by immune system on the recipient of the transfusion). The video below explains the concept of blood types and why some people can flexibly donate to all others blood types. Credit for this video goes to user nafis A on Youtube.

The problem with blood donations is that we can’t simply take many donations and stop worrying about blood reserves. This is because, just like milk, blood is perishable. Blood Centers Organization states that red blood can only be stored for 42 days before going bad. This creates a need for a continuous supply of blood donations to account for any emergencies.

On the bright side, the future of blood supplies look promising due to a recent publication by a research group at the University of British Columbia (UBC) at the Centre for Blood Research. They discovered a method to genetically enhance an enzyme which removes the antigens from blood. To do this, they used a genetic manipulation method called directed evolution.

David Withers’ Research Group at the Centre for Blood Research. Source: UBC Centre for High-Throughput Biology

This process introduces step-wise mutations in the DNA that encodes the enzyme. They use a multi-pronged approach by introducing many random mutations to the gene, and select the best performing mutants and do this for multiple rounds. The researchers at UBC claim that after five rounds of directed evolution, the enzyme which removes antigens from red blood cells is 170 times faster than the original enzyme. The original enzyme, although functional, was never fast enough to be a feasible way of removing antigens from blood. This genetically enhanced enzyme, however, can be used practically in the medical setting.

This discovery could potentially eliminate the shortage of antigen-specific blood by converting all donated blood to donor types! I think this has great potential for saving lives. From what I know about Biology, once the DNA of this hyper-enzyme has been sequenced, it can be easily generated from protein farms – where bacteria produce large quantities of the protein which can be purified and extracted for clinical use. I think it’s amazing to hear that my university is at the frontier of such impactful discoveries!

Blog by Justin Yoon

Commented on the following blogs:

Electronic cigarettes by Brian Cheng

Bioethics dilemma by Paul Yi

Imposter syndrome by Luxi Xu

Embalming Rosalia Lombardo

King Tutankhamun, Otzi the Iceman, and Lady Xin Zhui…what do they all have in common? They are all world-famous mummies. Here is another one: Rosalia Lombardo of Capuchin Catacombs of Palermo, Sicily, also known as the “Sleeping Beauty” of Palermo. The embalmed body of Rosalia has several characteristics that made it so significant and special among hundreds of other mummies that are thousands of years older: fleshy appearance, faint discoloration, and well-preserved internal organs.

Rosalia Lombardo was embalmed back in 1920, shortly after her death, by embalmer Alfredo Salafia. Being one of very few modern mummies, Rosalia shows potential to eternality, for showing almost no signs of deterioration 90 years after death. As one of the first embalmers to use formalin (a modern chemical known to have good preservation effect in preventing natural decomposition) in body preservation, Salafia is credited his choice and formula in creating Rosalia.

Lady Xin Zhui, Source: David Schroeter on Flickr

Lady Xin Zhui, Source: David Schroeter on Flickr

Other than formalin, Salafia included glycerine, zinc and salicyclic acid in his solution as well. Both formalin and salicyclic acid have hygienic effects: the former kills off bacteria, and the latter prevents fungi generation. Glycerine is effective in reinforcing the effects of formalin. Zinc is used of petrifying the interior, and maintaining the shape of the body. This fluid was injected into the corpse via the femoral artery (one of the main blood vessels located on the thigh) and the navel.

Upon inspections, Panzer and her team of researchers were able to determine extent of preservation of Rosalia’s body, despite the limitation that it has to be kept within the glass casket. Since touching and feeling the mummy was not allowed, based on observation, Rosalia’s head and cheek did not seem to have shrunk or distort. In addition, CT scan (a series of X-ray tests that produce cross-sectional images of the body) conducted on the body was able to show that most of the internal organs are still recognizable by shape.

There is no denial, however, that the body of Rosalia is starting to show signs of oxidation on top of numerous efforts made to conserve the body. This is the evident to the imperfection in human ability to embalm, as well as another reason to people to pursue for the ultimate perfection. Therefore, scientists today continue to tirelessly search for better alternatives in embalming, a profession that has been passed on for millenia and will continue for many more.

 

Hui Esther Lo

Trash to Treasure

Wouldn’t it be great to convert something that is harmful, yet naturally occurring in the environment to something that is useful to the human kind? That is exactly what a few researchers led by Dr. Da Deng at Wayne State University in Detriot did.

Multi-colored algae blooms may sound like one of nature’s many beauty wonders, however it is far from wonderful. Typically, these harmful algal blooms (HAB) consists of massive growth of one or more phytoplankton species, blooming up to a concentration of hundreds to thousands of cells per millilitre. These blooms of varying size can cover the surface of water for weeks. Some blooms are large enough, they can even be seen from space!

This satellite image capture algal bloom in Lake Erie Basin, taken on July 28, 2015. source: Nasa Earth Observatory

This satellite image captures the algal bloom in Lake Erie Basin, taken on July 28, 2015. source: Nasa Earth Observatory

In 2011, the algal bloom that occured in Lake Erie broke the record of worst algal bloom ever observed, topping the chart at 10 of the 10-point severity index. In August, 2014, the Toledo water crisis in Lake Erie left nearly half a million people without safe drinking water. Although the exact cause of algal bloom is yet to be determined, scientists believes that are many contributing factors including: water temperature, sunlight, current and presence of essential nutrients like nitrogen, carbon and oxygen. Although only a few algae species produce toxins, the effects they have on humans and aquatic life are detrimental as the toxins make their way up the food chain into animals we eat.

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[Video Courtesy to: Ohio Sea Grant]

Dr. Da Deng and his team of researchers aimed to reduced HAB in freshwater lakes by converting it to something useful. The team collected samples of  toxic HABs from Lake Erie, and converted it to hard carbon by heating it in argon gas at high temperatures of  700-1000 °C. Hard carbon, often derived from petroleum made from biomass, is an ideal electrode (electric conductor used to connect non-metallic part of the circuit), used for sodium-ion batteries. The final electrodes created by the researchers consists of 80% hard carbon (derived from algae), 10% black carbon and 10% binder. The scientists found that overall, the sodium electrode had a high capacity of up to 440 mAh/g in the first cycle. However, there were some issues of irreversible capacity loss after the first cycle, resulting in a lower capacity of 230 mAh/g.

Although, Lithium-ion batteries are more dominant in use right now compared to Sodium-ion batteries, sodium is more abundant and could potentially replace the more-expensive Li-ion batteries in the future. However, more extensive research still needs to be conducted to increase the stability and capacity issues with these algae-derived sodium electrodes to improve their performance in the future. The researchers also noticed that the temperature of which the algae was heated also affected its stability and capacity performance. This is something scientists can take in account as they aim to improve this discovery.

 

 

DNA TAKE ON A NEW ‘SUPERCOILED’ SHAPE

The iconic double helix of DNA that James Watson and Francis Crick first published in 1953 was not the end of DNA structure as new Study revealed.The double helix of DNA was just a tiny fraction of a real genome.It consists of 12 DNA base-pairs that later formed building blocks of DNA known as helical ladder.

DNA structure is made up of almost 3 millions base-pairs that must fit into nucleus of a cell which is just 10 micrometers across, thus DNA must really have to coil to fit into nucleus.

To get the bigger picture according to the new research,the researchers recreated DNA molecules in the lab. The researchers forced DNA strands to coil and recoil it at the same for several turns using short circular snippets of DNA that is made up of many base-pairs.
The researchers the discovered a panoply of a breathtaking new shape of DNA.YouTube Preview Image
Supercomputer simulations show how the dynamic motion of the supercoiled DNA causes its shape to change constantly to form a myriad of structures.

Most of which have different shape of DNA like handcuffs or sewing needles.Others through their coiling shape look like rods.
Supercoiled DNA strands

Photo credit: LIVESCIENCE/Thana Sutthibutpong

To make this ‘supercoiled’ DNA strands visible in the human body,researchers inserted an enzyme called human topoisomerase II alpha into the body to show how this ‘supercoiled’ DNA look like in the body.
The enzyme relaxed DNA twisted DNA in human body.This new discovery of ‘SUpercoiled’ DNA was reported today (oct 12) in the Journal Nature Communications posted by livescience that the structural shape of DNA created in the lab resembled the strands of DNA found in the cell nucleus.

The DNA samples were then froze and used a special form of microscopy to capture the first-ever images.
According to James Watson and Francis Crick, DNA helix is formed when complementary base-pairs like adenine and guanine are bound together which is now being contradicted by the new simulation of DNA in the new study that these base-pairs peel apart when the helix is unraveled.

The new discovered has shown us the complexity of the structure of DNA.It is now beyond double helix and it is so interesting to see how ‘supercoiled’ is DNA.

KUOL BIONG

Tragic Island Threatening Our Marine Life

Have you heard about a huge floating island of plastic? You may not believe it, but there it is in the central North Pacific Ocean, called the Great Garbage PatchThe size of the garbage patch is enormous estimated about twice the size of Texas! Charles Moore, the scientist who first discovered the garbage patch, mentioned that the garbage island will even likely double in size in the next ten years. The Great Garbage Patch has become a discourse of environmental debate for its adverse effects on marine life.

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Source: Flickr Commons

Though there are various types and sizes of debris, the majority of the marine debris consists of plastics. Algalita Marine Research Foundationan organization that studies sampling the marine debris to determine the density of plastic debris in the pacific garbage patch, analyzed the increasing ratio of plastic to zoo plankton by weight. This means that the concentration of plastic debris is increasing, contaminating the largest biome on Earth. Increasing accumulation of plastic debris leads to the biological loss by entanglement and ingestion. Every year, over 100000 ocean animals become trapped in marine debris and unfortunately, many of them die. In addition, many marine organisms ingest plastic debris, mistaking them as their food source, being poisoned and starved.

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Author: Chris Jordan Source: Wikimedia Commons

The chemical toxicity in plastics is another factor that deteriorates marine ecosystem. Plastic debris not only contains organic contaminants, but it also contains persistent organic pollutants such as pesticides and petroleum hydrocarbons, which are resistant to environmental degradation: they will remain in the water, aggravating and propelling the speed of contamination of marine life. Also, the high concentration of contaminants causes lethal threats to marine ecosystem as they accumulate in their body through ingestion. Contaminants, such as phthalates and Bisphenol A (BPA), adversely affect reproduction in many marine animal groups, disrupting the development of amphibians and inducing genetic abnormality. BPA acts as a feminizing agent that produces an estrogenic effect in fish. It also affects the processes of sex hormones and disrupts growth, insulin signaling, bone development and brain development. Furthermore, bioaccumulation of chemicals can occur; persistent organic pollutant can accumulate in the fatty tissues of organisms and higher the trophic level, the greater potentially the negative effect on birth or mortality of marine animals.

From the serious damages caused by the garbage patch, people have to be aware that we have caused the destruction of marine life. The environment constantly lets us know through diseases or disasters that it needs care, and people must pick up on the cues and change their behavior in order to save the world from a dark future!

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YouTube video courtesy of: National Geographic

By InHye(Lisa) Kim

I commented on :

Adrian Li’s post on Vitamin C. Miracle Cure or Wannabe Dud or Neither?

Grace Kim’s post on Almost there! Universal blood for all.

Julia He’s post on My Grandma Can Become Stronger by Eating Apples and Tomatoes.