Category Archives: Outreach Project

Exploding Arctic Seal Populations: Is Climate Change to Blame?

Melting ice. Rising sea levels. Intense weather patterns. We know it all too well. Now, what if I told you that certain types of seals in the Arctic are increasing in numbers despite all the other negative predictions associated with climate change?

Harbour seal by Steinkobbe

Katie Florko, a Ph.D. student at the University of British Columbia, observed increasing population changes of Harbour seals in the Churchill River Estuary for the last two decades. Florko’s research team believes that this increase is associated with melting ice sheets due to the recent atmospheric warming, consequently exposing the ground and water beneath. Harbour seals, unlike their Arctic neighbours such as Ringed seals, prefer laying on exposed rocks, sand, and mud banks instead of ice. The following video goes into the specifics:

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The Big Picture

       Anyone with background knowledge on ecology might question the effect of this increase on the stability and diversity of Arctic ecosystems. The answer is complicated. All plants and animals, including us, in an ecosystem are interconnected making it difficult to tell which way the populations will shift in fast-changing environments. However, the outcomes of climate change are generally negative. With alarming rates of melting ice, the Arctic region is where change is most evident. It is brought on by the continuous release of greenhouse gases into our atmosphere from increasing population energy demands, use of transportation fuel, and unsustainable resources. As a result of their warming habitats, Arctic species are forced to shift northwards, chasing their ideal conditions.

Melting Ice Cover in the Arctic by Jeremy Potter/NOAA

Drive for Deeper Understanding

     “The Arctic is one of the areas that is undergoing one of the most rapid changes related to climate change”, said Florko. Studying the Arctic and other regions of the world can provide a deeper understanding of the consequences of climate change on global ecosystems. People are also affected as melting ice brings on sea level rise, endangering coastal infrastructure world-wide

As crucial as Arctic research is, the investigation into the effects of climate change is not easy. Arctic research, specifically, requires extensive commitments, funding, and equipment. Only those brave enough to face the extremely cold conditions of the Arctic icefields go up to study its wonders. Nonetheless, modern-day technology has made it easier for scientists to travel north. The podcast below goes into more detail about the various aspects of Arctic field studies.

While Florko’s study solved a small puzzle piece of the effects of climate change in the Arctic, there is still substantial amounts of research needed to be done.

As for the non-scientists, it’s good to keep in mind that drastic changes are happening in places where most people might not see but that does not make them any less of a concern.

 

Written by: Ellena Yoon, Jocelyn Cheng, Polina Orlov, Brian Agafitei

A New Organic Compound has Potential in Removing Nuclear Uranium Wastes

          On September 20, 2018, Mohammad Chaudhry, a Ph. D student at the University of British Columbia and his team of researchers have produced a new chemical compound known as an expanded campestarene. This new compound is a large, cyclic molecular structure that possesses the unique property of binding strongly to uranium ions. This can have real-world applications in the future as a tool to manage nuclear waste since the uranium by-product produced by nuclear reactors is a growing concern. Expanded campestarenes’ ability to strongly bind to uranium ions can be used to specifically remove dangerous, radioactive uranium waste.

The hollow cavity of expanded campestarene in the middle will hold the uranium ion.

The Campastarene Creation:

          The process for making such a compound is not an easy process. It requires a lot of trial and error, and an extensive knowledge of macrocycle chemistry, a subsection of chemistry. Despite being an expert on this subject, it still took Chaudhry a lengthy time to obtain enough of these molecules to call it a success. According to Chaudhry, “I basically went through the periodic table, and I went through a list of which elements would make sense to work in this type of reaction, and uranium was one I thought would work.” Overall, this process took about eight months.

          After selection of uranium ion, a reflux reaction was used to produce the compounds. A reflux reaction is simply heating a bunch of chemical compounds in order to input energy and make the reaction more likely to happen. “Basically, you mix it and you heat it and then you purify it, and that’s it,” says Mohammad.

          The following video contains the journey that Chaudhry and his colleagues have taken to create this molecule.

SO Project Group 5 Video” by Group 5 is licensed under YouTube.

The Uranium Situation and the Campastarene Solution

          The expanded campestarenes produced by Chaudhry’s team are very unique molecular compounds. The most notable property is its ability to bind strongly to uranium ions. The expanded campestarenes have an internal cavity that can specifically bind to uranium ions, forming a very stable complex. As a result, it is a useful uranium sequestering agent. Uranium sequestration describes the process of removing uranium ions from solution by strongly binding to it.

          This property can be extremely useful when it comes to managing uranium waste produced by nuclear reactors. With our increasing need for nuclear energy, more uranium waste is being produced. There are two types of uranium waste produced from these power plants: non-radioactive and radioactive uranium.  Radioactive uranium is dangerous to humans and the environment. It can damage one’s DNA, cells, tissues, and organs, and can also contaminate groundwater and soil, drastically impacting the environment. In addition, uranium waste is very difficult to get rid of because it takes hundreds-of-thousands of years to decompose naturally

          However, removing radioactive uranium is not as easy as it may seem. It is hard to differentiate the safe, non-radioactive uranium from the harmful, radioactive uranium. Therefore, by creating an expanded campestarene that can specifically bind to dangerous, radioactive uranium, it can be safely removed. This binding process is called chelation, where a molecule with specific structure allows it to target specific metal ions (like uranium).

         The following podcast by SCIE 300 Group talks about the daily-used chelating agents, such as chelating food additives and chelating agents in water purification. Also, the podcast contains an interview with Mohammad Chaudhry about the practical implication of expanded campestarene.

SCIE 300 SO Project Podcast” by Group 5 is licensed under YouTube

          Although uranium sequestration has practical applications, especially when it comes to nuclear waste, modifications to Chaudhry’s expanded campestarenes still need to be made before it can be used for practical use. “This experiment was mostly an academic curiosity,” Chaudhry says. However, Chaudhry’s discovery has set the foundation for future research on the topic of expanded campestarenes. Perhaps in the future, the specific binding nature of expanded campestarenes can be put to applicable use, especially in dealing with the radioactive uranium waste problem.

Alzheimer’s and research on a possible cure?

Alzheimer’s is a disease that has been distraught on families for decades. It starts by damaging the brain cells, eventually killing them off, and causing dementia (memory loss) as a result. Current medical resources can slow down symptoms but no cure has been found yet.

Source: https://drjockers.com/alzheimers-disease/

Recent research that points to decreasing levels of steroids in the brain (neurosteroids) and the risk of Alzheimer’s with increasing age suggests that Alzheimer’s might be related to the decreasing neurosteroids. In response to this, Dr. Daniel Tobiansky has found that the brain likely produces its own testosterone, and testosterone has been found to decrease inflammation of cells in male rat brains.

The Research of Dr. Daniel Tobiansky:

The human brain has always been thought to be a passive recipient of steroids such as testosterone and estrogen from our body. However, researchers may have found recent evidence that suggests otherwise. In particular, Daniel Tobiansky, a postgraduate doctoral fellow at the University of British Columbia performed an experiment, with gonadectomized (removal of testes or ovaries) rodents to observe the difference in sex-steroid levels of the brain in contrast to the control animals (not gonadectomized). If the brain indeed does not produce its own steroids, then, control animals should observe regular levels of steroids in the blood while others have none due to the lack of sexual organs.

What They Found:

The results of the experiment came just as hypothesized, with no signs of testosterone in the blood. Interestingly, parts of the brain such as the mesocorticolimbic system that functions as the “reward system” of the body, were found to have the same levels testosterone as it was in the control animals. This incredible in the context that further understandings to this simple discovery that the brain produces its own steroids can suggest potential cures to diseases and disorders such as depression and Alzheimer’s.

Source: https://slideplayer.com/slide/5724554/

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Conclusion:

There is currently strong evidence suggesting that brain damage is related to the regression of neurosteroids. If Alzheimer’s is indeed associated with decreasing neurosteroid levels in the brain, then ramping up those steroid levels might help with slowing down the disease or even curing it.