Tina received a Four-Year Doctoral Fellowship. Congratulations!
Congratulations to Jason Hedges
Jay received a 2019 UBC Chemistry Award for Graduate Research Excellence.
Congratulations, Jay!
Piperazic acid-containing natural products
Our new review article on piperazic acid-containing natural products is online at Natural Product Reports.
Check out all the exciting piperazic acid-containing molecules.
Congratulations to Kalindi!
Farewell to Jin
It was Jin’s last day, and we sent her off with a goodbye lunch. She is off to join Applied Biological Materials (ABM) in Richmond, BC where she will be doing some cool work in biotech.
Good luck, Jin! We will miss you!
A Two-Enzyme Pathway Links L-Arg to Nitric Oxide in N-Nitroso Biosynthesis
N-nitroso compounds are carcinogenic molecules previously thought to be made only through non-enzymatic routes. We investigated how the N-nitroso natural product streptozocin is constructed, and we revealed a new two-enzyme pathway that links L-arginine to production of nitric oxide. Congratulations to Hai-Yan and coauthors for their recent publication in JACS!
Mel Higgins receives the Founders Award from the ACS
UBC Chemistry Postdoctoral Fellow Mel Higgins received the 2019 Founders Award from the American Chemical Society Biological Chemistry Division. This award was established in memory of William P. Jencks’ contributions to mechanistic enzymology and is given to an outstanding PhD student or postdoctoral fellow in biological chemistry.
Mel presented her award lecture “Characterization of a heme-dependent N-N bond forming enzyme” at the Winter Enzymes Conference in New Orleans in January 2019.
Grace Ho joins the lab
Welcome, Grace!
Haru’s goodbye dinner
See you again soon, Haru!
PLP-dependent reactions in natural products biosynthesis
Our new review article on pyridoxal phosphate-dependent reactions in natural products biosynthesis is now online.
Check out all the amazing reactions PLP-dependent enzymes can catalyze!
Tina Rothchild joins the lab
Welcome, Tina!