Tag Archives: Cancer

Think you know your spit? Think again.

How would you feel if you couldn’t taste or swallow your food? How about if speaking was uncomfortable? Having a dry mouth, or not having enough saliva, can cause these unpleasant symptoms.

Most people don’t know all the uses of saliva or the importance of it. Take a listen to our podcast below to see for yourself.

Audio source: Own project group

As was mentioned in the podcast, saliva is necessary not only for digestion of food, but also for tasting, oral health, prevention of bad breath, chewing, fighting germs, preventing tooth decay and communication. Researcher Hal Clark and his team looked into saliva loss resulting in a condition called xerostomia, more commonly known  as dry mouth.

Xerostomia is known to cause a decrease in patient’s quality of life, such as discomfort in speaking and swallowing, pain and possibly anxiety and sleep disturbance. So what causes xerostomia? One of the main causes of xerostomia is linked to radiation therapy for patients with head-and-neck cancers. Radiation therapy consists of targeting X-rays to the area of the tumor (external) or inserting a device near the tumor that emits radiation. Hal Clark and his team investigate loss of saliva due to dose of radiation therapy, or amount of X-rays, for head-and-neck cancer patients.

Source: Own project interview

Source: Own project interview

In this recent study, patients underwent radiotherapy treatment for head-and-neck cancers at the BC Cancer Agency. The researchers collected saliva output from the patients 3 months and one year after radiation therapy. Hal then compared this output with that of baseline, or the saliva output before radiation therapy. Clark found that the average loss of saliva after 3 months was 72% of baseline and the average loss after 1 year was 56% of baseline. To conclude his study, Hal suggested a minimum radiation dose to the main salivary gland to greatly reduce the chances of xerostomia.

In the following video, Hal and his supervisor, Dr. Steven Thomas explain saliva output measurements and radiation therapy treatment.

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Video source: Own project interview

The machine seen in the following video of the patient’s point of view when receiving radiation treatment is the same technology that Hal Clark and his team used for radiation treatment in their study.

Video source: from Vimeo

The level of saliva output affects the patients’ quality of life. Therefore, to reduce the side effect of radiation treatment, researchers are working hard to find the right balance between killing the tumor and maintaining the saliva output of patients. Tasting, swallowing and even speaking would be uncomfortable and painful if you had xerostomia. To put it simply, the fact that efforts are being made to reduce dry mouth shows that our saliva is important. So…don’t forget about your spit!

Surekha Gangar, Seungwon (David) Lee, Jay Wong, Uttara Kumar

Clearing Up The Smoke Around E-Cigarettes in Vancouver

Late last year, Vancouver made the controversial move to ban the use of  electronic cigarettes (e-cigarettes) in public places where smoking is prohibited as well as their sale to minors. The controversy behind the ban was evident by the results of a poll by Metro News, where out of over 2500 of its readers, 65% of people opposed the ban.

This may be because many people think of e-cigarettes as a less harmful alternative to smoking cigarettes, similar to that of products such as nicotine patches or nicotine gum. However, it is worth noting that in Canada, only e-cigarettes that do not contain nicotine can be legally sold which means that e-cigarettes may not curb cravings as well as the aforementioned nicotine containing products. Regardless, when it comes to their safety in comparison to cigarettes, opponents may be on the right track. When the Canadian Cancer Society was asked whether e-cigarettes were less harmful than cigarettes, they said, “Yes, because the products contain no tobacco, nor tobacco smoke.”

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E-cigarette and Cigarettes Side By Side Source: Flickr Commons                             Credit to: TBEC Review

So if e-cigarettes appear to be less harmful than cigarettes, why the big fuss? An article in the Vancouver Sun about the topic made it clear that one of main causes of concern is the effect of e-cigarettes on youth. In the article, Dr. Meena Dawar, a medical health officer with Vancouver Coastal Health, says that although e-cigarettes aren’t proven to be linked to any cancers, they are quite new and the vapour they produce may still contain certain carcinogens, cytotoxic chemicals and heavy metals present in tobacco smoke. Moreover, a study published in The New England Journal of Medicine found that high levels of formaldehyde, a cancer causing agent found in cigarettes, was present in some varieties of e-cigarettes which is a concern as it would eventually be inhaled by the user.

Lastly, an article in the Metro adresses the concern that e-cigarettes are normalizing the concept of smoking  and are diminishing the work that has gone into making smoking ‘taboo’ in our society. Additionally, proponents for the ban argue that advertising for e-cigarettes often seems to be targeted to youth in terms of the different flavours available and the ‘fun’ packaging.

The YouTube video shown below is a great summary of the potential health risks of e-cigarettes.

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Credit:  CNN on Youtube

In summary, although there is not much conclusive evidence out there on the dangers of using e-cigarettes compared to what is out there for cigarettes, I personally support Vancouver’s decision to go ahead with the ban because e-cigarettes are relatively new and it is hard to evaluate their long term effects. Additionally, when it comes to the health of our society, I don’t think it’s ever a bad idea to err on the side of caution.