Category Archives: Issues in Science

That’s Nuts! A New Take on Allergy Treatment

Everyone knows the best way to treat allergies is to avoid what causes them, right? Well, according to a recent study that is not the case. But before we go into that, we need to know a little about what allergies really are.

food-allergies

Image credit: Salt Room Millenia Wellnes Center

Everyone has heard of them, but what are they really? Generally speaking, an allergy is an over-reaction of the body’s immune system to something that is harmless for most people, such as eggs, pollen, or peanuts. These substances are called ‘allergens’, and the immune responses they cause can do serious harm. More information on allergens can be found in the video below, credit to eMedTv YouTube channel.

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So, why do people have allergies anyway? This question stumped scientists until DP Strachan proposed in 1989 that allergies develop primarily from the lifestyle changes of our modern society, such as increased hygiene and cleanliness. This idea has come to be commonly known as ‘the hygiene hypothesis‘. The basic principle of the hypothesis, that less exposure to certain substances causes allergies, appears to hold true under more recent analysis.

Food Allergies cause 200 000 emergency room visits each year in the U.S., with more than 15 million Americans living with food allergies. From 1997 to 2008 the number of reported peanut allergies in the U.S. tripled, breaking three million cases according to Food Allergy Research and Education (FARE). This time period coincided with increasing attempts to lower exposure of children to peanuts. Clearly something isn’t working.

Nut Free Logo Nut free school logo

Image credit: Logo-kid.com

With understanding of allergies, why they arise, and how they affect people, the importance of finding effective treatment methods becomes clear. Using logic that follows from the hygiene hypothesis, one research group may have found a strikingly simple solution.

In a paper published February 2015, Du Toit and associates studied 640 infants, 4-11 months old, that were at risk of developing peanut allergies and separated them into two treatment groups. The first group were exposed to small amounts of peanut butter routinely, while the second group completely avoided peanuts, continuing until 5 years of age. The group with peanut exposure developed peanut allergies with remarkably-less frequency than the second group(1.9% compared to 13.9%).

So what does this mean? Should people start feeding their kids peanuts to avoid a serious allergy? The answer to that is absolutely not. This study was undergone with careful scrutiny by expert physicians to ensure minimal risk. What it does mean, is that allergy treatment is going to be changing in the near future, and hopefully the rate of allergies changes too.

-Dixon Leroux

Moving Beyond Silicon (Part Two): The Unlimited Potential of Graphene

In Part One of this series, I discussed an overarching trend in computer science called Moore’s Law. This law (think of it as a law of computer nature) states that roughly every two years, the overall processing power of the conventional computer will double. Now, while this may be exciting to the consumer who cannot wait to get their hands on a faster computer for the same price; the consequences of this law for the computer engineers who create the devices, have never been more challenging.

The most difficult of these challenges is that as more components are put into the central processing unit (CPU) of a computer, the components will need to become so small that they will eventually reach the size of a single atom! Once at that hard limit, there will simply be no more room left in the microchip for more components. Consequently, the method of how we manufacture computers will need to be drastically reimagined if technological innovation is to continue in the foreseeable future.

Moore's Law and Technological Innovation

Moore’s Law can be directly linked to technological innovation. As our computers become more powerful, cutting-edge technologies proliferate. Credit: Humanswlord (WordPress)

That said, as many novel options for how to compute information differently have become available, scientists have wondered if the problem lies in what we compute our information with. Particularly, what if extending Moore’s Law for the next century meant that we only had to change the material we make our computers with? Enter the miracle material, graphene.

Put simply, graphene is a very thin layer of carbon, measuring only one atom thick. These single carbon atoms are packed together tightly to form what is known as a hexagonal honeycomb lattice.

Graphene in a Hexagonal Honeycomb Lattice

Graphene in a Hexagonal Honeycomb Lattice. Each carbon atom (represented by the “C”) is perfectly bonded to it’s neighbours. Credit: Karl Bednarik (Wikimedia Commons).

This unique structure of carbon atoms makes graphene the thinnest, lightest, strongest, best heat and electricity conducting material known to science. Not only that, but due to carbon being the fourth most abundant element in the universe, it could very well be the most sustainable material also.  However, it isn’t what graphene is that makes it so spectacular, but what it can do when put it to the task of computation.

In 2013, IBM showed their first generation of graphene-based integrated circuit (IC). Just this last year, IBM announced another breakthrough in creating its next generation of IC built with graphene. In this new generation of graphene based IC, IBM layered graphene in the channels of a microchip (the spots where electricity is conducted and electrons are moved around). From applying graphene in this way, IBM found the microchip to be 10,000 times faster then the current silicon alternative which uses copper. From this, IBM claims that graphene based electronics possess the potential to reach speeds upwards of 500ghz (that is 500 billion operations per second or 20 times faster then the conventional laptops sold today). This is made possible because graphene has little to no electrical resistance, which means it can move electrons around the processor much more efficiently then copper ever could.

With that said, there are still many hurdles which must be passed before graphene makes it into your next mobile device. For one, graphene based IC’s remain incredibly difficult to build using traditional processes for manufacturing microchips. IBM stated that current methods of creating graphene for use in IC’s remain expensive and inefficient. That said, it is only a matter of time before manufacturing processes are streamlined and the great graphene revolution in computer science begins!

For more information on graphene, check out this video by SciShow below.

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Vive la graphene!

– Corey Wilson

One Breath Closer…

According to the World Health Organization (WHO), the leading cause of death worldwide is cancer. More specifically, lung cancer is the most common type of cancer in the world. This terrible disease does not discriminate when it comes to victims. It afflicts both genders, and people of all ages and ethnicities. Luckily, scientists have been working on a new detection device for lung cancer that holds promising benefits for patients. We are literally one breath closer to early detection and treatment of this terrible disease.

lung-cancer-faims

The LuCID Device, Source: Google Images

The article, Ground-Breaking Lung Cancer Breath Test in Clinical Trial, published on February 14, 2015 states that a breath test shows hopeful advancements in detecting lung cancer. Scientists at the University of Leicester have begun the clinical trials of the Lung Cancer Indicator Detection (LuCID) project. LuCID is a device that detects Volatile Organic Compounds (VOC) at low concentrations in a patient’s breath. The evaluation of VOC’s in a patient’s breath can serve as a biomarker to detect lung cancer.

Dr Siddiqui, the lead researcher in this study, states that lung cancer has one of the lowest survival rates of all cancers. More importantly, he emphasizes the importance of early detection to improve a patient’s prognosis. Basically, the earlier the cancer is discovered, the greater the chance of survival for the patient. For this reason, the LuCID device may just be the missing key to early detection. The device is also cheaper, more efficient, and less invasive compared to other detection methods. For example, performing a CT scan exposes the patient to harmful radiation that could result in further health complications. Another downside to invasive techniques is that they are not suitable for everyone, especially children and pregnant women. Overall, the breath test is a safer alternative to more conventional lung cancer detection methods.

The Presence of Lung Cancer Source: Flickr Commons

The Presence of Lung Cancer
Source: Flickr Commons

Though the LuCID project is still in clinical trials, it is showing promising results in early detection for lung cancer. Catching lung cancer at an early stage can give patients a much better chance at fighting this disease. Furthermore, this new procedure may potentially lead to more safer and non-invasive detection methods for other diseases as well.

Check out the BBC News coverage on the LuCID device. The video was uploaded by the user KaFaDoKyA NEWS.

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– Navjit Moore

Is Artificial Photosynthesis a Solution to the Global Energy problem?

One of the greatest problems facing mankind is the search for renewable energy. One potential solution is inspired by photosynthesis in nature. Photosynthesis combines water, carbon dioxide(CO2) and energy from the sun to store energy as sugar, which also releases oxygen. This principle is illustrated below.

 Photosynthesis

Image source: National Energy Education Development Project (NEED)

The idea behind artificial photosynthesis is to create a man made system, or ‘artificial leaf’, that allows water and sunlight to react and form hydrogen gas(H2) to store chemical energy instead of glucose(sugar). This is significant because the hydrogen gas can be stored and utilized as a fuel source.

David Nocera of Harvard University explains the basic principle of artificial photosynthesis using an artificial leaf. Nocera also goes on to say that artificial photosynthesis still has to overcome high engineering costs to become commercially viable. Nocera’s lab is actively researching the topic to try and find more economical methods of artificial photosynthesis. Full David Nocera BBC interview below.

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One review paper visually illustrates how a large scale H2 power plant could operate using sunlight and seawater as inputs. Also shown are green energy sources to enable the power plant to be completely self-sufficient and sustainable.

Vision of a sustainable hydrogen fuel community based on APS.

From Nature article: ‘Artificial photosynthesis for solar water-splitting’ by Yasuhiro Tachibana, Lionel Vayssieres & James R. Durrant

New research suggests that in addition to creating a hydrogen fuel source, artificial photosynthesis may be able to lower atmospheric CO2. This would require a system that more closely emulates natural photosynthesis, using CO2 as well as water and sunlight to create a type of hydrocarbon(contains both hydrogen and carbon) fuel. Atmospheric CO2 is a major contributor to climate change so this would effectively be ‘killing two birds with one stone’ as far as global issues are concerned. The possibility of reducing atmospheric CO2 further sells the case of artificial photosynthesis as a leading energy source for the future.

Artificial photosynthesis surely has some desirable qualities, but is it the solution to the global energy problem? Well, possibly, but not in the immediate future. A full switch to H2 fuel would be a long process involving engineering of new infrastructure for transportation, such as motor vehicle engines.

Research on the topic is fast evolving and it will not be long until artificial photosynthesis is highly efficient with cheap materials. The real challenge now will be turning laboratory research into a large-scale commercially viable energy source. Can we do it? Only time will tell.

-Dixon Leroux

Sitting Leads to Premature Death?

Right now, as you are sitting and reading this blog, you are inviting a premature death. A recent study by Biswas et al. in the Annals of Internal Medicine journal states that sedentary time, i.e. time sitting down, shows a correlation to the risks of cardiovascular disease, type 2 diabetes, obesity, and some cancer types. These diseases allude us to people lacking physical activity however, in the study done by Biswas et al., it is suggested otherwise.

Sedentary Time. Source: Google Images

Sedentary Time. Source:Simpsons Wikia

Physical activity is emphasized deeply in our everyday lives. Data shows physical inactivity has led to many of deaths and is believed that physical activity decreases the risk of diseases. However, in the study done by Biswas et al., the correlation between sedentary time and diseases is independent to physical activity. A related study suggests that reallocating 30-minutes of sedentary time everyday showed to be slightly beneficial, whether it be sleeping, physical activity, or even standing up. The study showed unspecific benefits and were not able to come to a conclusion that physical activity was beneficial.

Pressure Points. Source: Wikimedia

Pressure Points. Source: Wikimedia Commons

 

A CNN coverage on this topic by Jen Christensen suggests that a person should stand up every 30 minutes for 1-3 minutes in order to reduce the risks of these diseases. The coverage suggests that when a person is standing up, there are some pressure points in the body which are activated so that the body secretes certain types of chemicals essential for the body. However, when sitting down, the body does not generate these chemicals hence the increase risk of diseases.

 

The next video describes in further in detail on how the body responds to prolonged sedentary time.

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Everyone nowadays spends at least half of their day sitting down, whether it be at home watching TV, at work finishing up a presentation, or even sitting down to read a book. Contrastingly, healthy living is emphasized so greatly in our lives. Balancing healthy living and our normal lives can be struggling, but taking small steps can help reach that struggle. Standing up and stretching every 30 minutes or so can help, as well as exercising at least 10 minutes a day can decrease the risk of harmful diseases.

-Tommy Kim