Tag Archives: Biology

Hiding Beneath our Noses: A New Subspecies of Goshawk

Could there be a new subspecies of bird hiding beneath our noses?

Researchers at the University of British Columbia (UBC) have recently discovered a new subspecies of Northern Goshawks  living on Haida Gwaii.  They looked at DNA of Northern Goshawks and found the birds on Haida Gwaii were different from those found anywhere else. This stunning discovery will help improve current policy and conservation efforts for these endangered birds.

Courtesy: Flickr | Photo Credit: Aleksander Cocek | A Northern Goshawk.

Northern Goshawks are native to British Columbia. These medium sized birds have sharp beaks, large talons, and live in British Columbia’s (BC) mature forests.  They are birds of prey and feed on other birds, small mammals, and even insects.  To learn more about these amazing birds, check out this interesting Scie 300 Podcast.

For decades, the birds along the coast have been seen as one species.  However, recent evidence suggests the birds on Haida Gwaii, an island archipelago off the coast of central BC, may be a subspecies of their own.  Kenneth Askelson is one of the researchers behind this study.  Kenneth explained the 433 samples they had was one of the largest collections of its kind and relied on contributions from museums and collectors.  “To collect all these samples by hand would have taken 30 years,” he explained.  Kenneth and his team analyzed the genetic samples and found differences not found in samples from other locations.

Goshawks numbers have been falling around the province, and the species along the coast is officially listed as endangered. There may only be about 1200 of these birds left in BC.  The population on Haida Gwaii is even smaller and estimated to have only 50 individuals. This small population is also at risk of inbreeding. Inbreeding is when closely related birds mate with each other. This can produce children that are more susceptible to changes in the environment or have genetic defects. It is not known for sure why these birds have remained isolated for so long.

Courtesy: Flickr | Photo Credit: Nick Goodrum | A Northern Goshawk spreads its wings.

This begs the question, are we doing enough? Human population growth has caused many species around the globe to disappear, and many more are at the verge of disappearing.  The Goshawk is seen as an important indicator of forest health. If the Goshawk species is struggling, the forest may also be struggling.  Current efforts to prevent further loss of this species include the creation of Wildlife Habitat Areas. The government of BC hopes to have 90 such areas set up by 2020, with many of these being created on Haida Gwaii.

However, effective conservation depends on knowing where species live and the  issues they face.  Mr. Askelson prides himself on, “being someone who can provide the most information to make the best management decisions possible.”  This study will help policy makers make informed decisions that could save the Haida Gwaii Goshawks from disappearing.

Goshawks are pretty cool, aren’t they? Check out this short video for more information.

 

 

-Sukhman Bhuller, Farhan Muhib, Janet Lee

Predicting Marine Populations with Phytoplankton

View of Earth from space. Photo from Wikimedia Commons.

Did you know that the ocean is predicted to warm over 4°C  the next 100 years? There’s certainly more than meets the eye when it comes to understanding the effects of global warming, and knowing how ecosystems change in response to changes in temperature can help make our efforts more focused and accurate.

As a recent PhD graduate from the University of British Columbia, Dr. Joey Bernhardt is already making waves in the science community. Her most recent paper describes the use of phytoplankton to analyze growth rates among species under different temperature conditions. Most of the study’s work actually occurred just last September, and we were lucky enough to be able to meet Dr. Bernhardt to explore the bigger picture issues she’s addressing.

What’s so special about phytoplankton?

Green swirls of phytoplankton in the Baltic Sea. Photo from Wikimedia Commons.

To debunk a common misconception: not all of the oxygen we breathe comes from trees. In reality, nearly 50% of the world’s oxygen supply is produced by phytoplankton. What’s more, phytoplankton serve as the basis of marine food webs, so it’s no surprise that they were the main subjects used in Dr. Bernhardt’s study. These remarkable organisms can actually help us make predictions about species populations in the context of global warming.

What issues are being addressed?

2070-2100 global warming predictions map. Photo from Wikimedia Commons.

One of the most pressing issues in our global warming narrative surrounds how temperature changes affect species population. While it’s easy to measure population growth rates in the controlled conditions of a lab, Dr. Bernhardt explores whether we can apply these results to the unpredictable, fluctuating temperatures of the outdoor environment.

If we were to disregard the fact that in nature temperatures fluctuate, we will ultimately make inaccurate population predictions. To generate a more realistic sample, Dr. Bernhardt collected phytoplankton off the coast of Vancouver Island and placed them in lab incubators that mimic a natural environment using a variety of temperature settings.

To gain a better understanding of the methodology behind Dr. Bernhardt’s study, check out our video:

https://youtu.be/F5rC4PLMsds

Why should I care?

When a species find themselves in an environment outside of their normal temperature range, they will either die off or relocate to more habitable areas. This now presents an entirely new problem since it’s not always easy for the communities that rely on these populations to pack up and move as well. From an economic standpoint, there are whole industries built upon the reliance that these populations will return, year after year.

The Future of Global Economic and Climate Change Issues

These experiments allow us to see the range of temperatures at which a species can persist. We can then pair this with the knowledge of how temperatures around the globe will shift over time in order to build more sustainable communities.

We take a deeper look into the applications of this technology in our podcast:

Group 213-5: Danny Israel, Christy Lau, Christina Rayos

Do humans have superpowers? -Magnetoreception

What if you had a superpower? What would you want it to be? The ability to fly? Superhuman strength? Well, what if the ability was to tell which direction the sun would rise from without actually seeing the rise, or just finding your way back to camp when you get lost in the woods? Researchers from Caltech and the University of Tokyo have found evidence that humans can subconsciously detect changes in the Earth’s magnetic fields.

Although this study only suggests that the effects of changes in magnetic fields are detectable by our subconscious brain, they feel that this could open up the window for new research. Prof. Shinsuke Shimo, in a YouTube video with science communicator Derek Muller says, “This is just the first step to make sure that it’s not theoretically impossible that our ancestors might have utilized this ability for their navigation.”

 

Derek Muller from Veritasium takes the test of magnetoreception

The ability of an organism to detect magnetic fields to identify directions, altitude or location is known as Magnetoreception. Have you ever wondered how pigeons are always able to find their way home? Or how birds know which direction is south when they migrate? Evidence of magnetoreception has even been found in dogs that will usually sit in North-South direction while they poop.

Prof. Shimo also believes that this ability may potentially reside in modern humans. Not so long ago, Prof. Joseph Kirschvink of Caltech claimed that he had discovered magnetoreception in humans. A few years later, Kirschvink, along with Shimo and co have found evidence suggesting humans may potentially posses a superpower.

It is important to remember that as of this moment, humans are only capable to detecting changes in magnetic fields subconsciously in a state with no distractions from the surroundings. However, if we were able to study and bring this ability to the consciousness, we would not only be gaining a superpower but also making inroads into bringing other parts of subconsciousness into consciousness.

If you wish to learn more about magnetoreception, you can watch this short video by Science Magazine.

 

 

 

Maybe my mom was right…

Ragged, calloused fingers danced across the damp ivory keys of the slightly out-of-tune instrument. A nocturne echoed, howling across the room, as the fear of failure kept his teary eyes glued upon the page. A metaphorical chain shackling him to the traditional device of torture twisted deep into the flesh of his aching wrists. A slave to the music. Broken, tired, and hungry. Those dark and terrible years would haunt him for the rest of his life.

As soon as I could walk, I was forced to play the piano. The daunting task of rehearsing the same piece for hours enraged my heart as a child, and when I asked my mom “why?” she always replied with “you’ll appreciate it when you’re older.” After 14 years of slaving away on that wretched instrument, along with having symptoms of carpal tunnel syndrome, I realized, maybe she was right. I was privileged to have an opportunity that she hadn’t had when she grew up and it allowed me to appreciate music further as well as learn other instruments with ease. But beyond this, I questioned, “in what other ways did I benefit from playing an instrument?” As a kid, I remember overhearing how playing piano had some correlation between being better at math, and although this seemed crazy, it led me to ponder the effects that playing instruments had on the brain.

 

Piano Keys By Elliot Billings 

How does playing an instrument affect the brain?

Today, the study of the brain is conducted by monitoring participants as they complete tasks such as reading or mathematical equations. Neuroscientists have found, that in doing such specific areas of the brain were activated. When monitoring the activation as participants listened to music, they found multiple areas across the brain firing all at once which differed from other activities.  Moreover, when playing a musical instrument nearly the entire brain was stimulated.

How does this transfer over to things outside of music?

Just as working out makes a person stronger, practicing an instrument is found to strengthen the brain functions used. For example, since studies show that there are common mechanisms used when playing an instrument and reading, it can be said that music can be used to promote child literacy. Similar suggestions from other studies can also be said for playing an instrument with linguistics and mathematics. These benefits, even when done as a child, were retained all the way into adulthood.  Furthermore, the act of playing an instrument utilizes both sides of the brain. In doing so, musicians are found to have increased volume and activity in the brain’s corpus callosum, which is what links the two sides together. This means that the brain has an easier time sending messages from one side to another, which could be beneficial as each side focuses on different processes. The TED-ED video below goes into further detail on the topic. 

The Corpus Callosum by Henry Vandyke Carter

So, in the unfortunate case that I end up with a child, I’ll probably get them to learn an instrument at a young age, and if they ask why, I’ll tell them “You’ll appreciate it when you’re older.”

-Nelson Bulaun

 

 

 

Help! I can’t stop eating!

A child eating pizza. Image from Wikimedia Commons

One slice of pizza turns into five boxes of pizza and twenty hours later… you’re still eating! Imagine an insatiable hunger and a love for food turned deadly. When eating becomes your worst enemy, Prader-Willi Syndrome may be the culprit.

What is Prader-Willi Syndrome?

Prader-Willi Syndrome (PWS) is a rare genetic disorder in which an individual feels hungry all the time. So much to the point where they are found constantly eating, and can continue eating even after they’re full. These individuals can literally eat to the point of death.

PWS was first described in 1956 by Swiss doctors Andrea Prader, Alexis Labhart, and Heinrich Willi. Anyone can develop PWS, and it was found that this disorder affects nearly 1 in every 15,000 births. As a result, PWS is one of the leading causes of childhood obesity.

Symptoms of a Deadly Appetite

The most common symptom of PWS is chronic hunger. Other symptoms can include: poor muscle tone during infancy, early-onset obesity, limited growth, delayed motor and verbal skills, behaviour and mental disorders, and curvature of the spine.

A 15-year-old child with typical PWS facial features. Note the presence of mild truncal obesity. Image from Wikimedia Commons

How does this happen?

PWS is a genetic disorder, which means that children inherit this disorder from their parents. Specifically, from an abnormality in a chromosome that comes from the father. This abnormality arises when a part of the gene is missing or malfunctioning. When this occurs, the hypothalamus (the part of the brain that controls hunger and thirst and releases hormones that promote growth) stops working which results in an inability to regulate food intake.

Is there a cure?

Unfortunately, there is no known cure for PWS. In fact, most of the research to date has only been targeted towards developing treatments for the disorder. For example, doctors may prescribe a growth hormone to treat PWS that not only increases height, but also decreases body fat, increases muscle mass, improves weight distribution, increases stamina, and increases bone mineral density.

Ultimately, the inability to regulate food intake remains one of the biggest obstacles that prevent individuals with PWS from living independently. There is still no effective medication that aids in regulating appetite. Nevertheless, those with PWS can still live a long and fulfilling life with the right guidance and support, as seen with Katie in the video below. Her documentary on living life with PWS gives us a better insight into the disorder, and presents a new meaning to the saying “you are what you eat”:

Documentary of Katie, a child living with PWS. Video from Youtube.

-Christina Rayos

Can Sharks Help Us Cure Cancer?

There are very few things in this world that are more terrifying to humans than sharks are. After all, with their intelligence, size, agility and ideal anatomical features, they really are the perfect predators. They have dominated the ocean for over 400 million years, instilling fear in other animals and humans alike. But what if these fierce hunters actually hold the key to surviving some of our deadliest diseases?

A great white shark in Dyer Island. Courtesy of Wikimedia Commons (Olga Ernst).
Source: https://commons.wikimedia.org/wiki/File:Great_white_shark_Dyer_Island.jpg

Recently, scientists at the Save Our Seas Foundation Shark Research Center characterized the full genome of a great white shark, essentially the genetic blueprint that maps the structure and function of the animal. Their studies revealed that sharks are just as resilient on the inside as they look on the outside.

Their research, published in the Proceedings of the National Academy of Sciences of the United States, found that sharks can repair and alter their DNA, the material in our bodies that carry genetic information, in order to fight diseases and heal wounds efficiently as they age. Their built-in resistance to DNA damage increases their genetic stability and health, which is how they are able to thrive for millions of years.

A 3D-model of DNA strands.
Courtesy of Flickr Commons (Helen Carmody).
Source: https://flic.kr/p/R8JhxZ

Healing progression of a lemon shark over a three year period. Courtesy of YouTube (Ramon Llaneza Technical Diving). Source: https://www.youtube.com/watch?v=-lrn5AHipp8. 

Our cells, the building blocks of our body, along with our DNA, which provide the layout for the cells to function, breakdown as we age. This damage, termed genomic instability, is what makes humans so vulnerable to serious age-related diseases like cancer.

By studying the shark genome, the scientists hope to understand the mechanisms behind how these animals are able to preserve its stability, information that may potentially help us fight cancer and other serious human diseases. It may also help improve current flesh-healing treatments.

There is still so much to learn from sharks, both from a biomedical perspective and from an environmental perspective. Hopefully, this newfound research will heighten our appreciation for these evolutionary superheroes instead of feeling the need kill them.

– Justine Law

The Fall of Sea Stars

1986-014-01: Sunflower seastar

1986-014-01: Sunflower seastar” by August Rode is licensed under CC BY-SA 2.0

Once an abundant species of sea star, the sunflower sea stars have become harder to find on the West Coast of North America. A recent study co-led by the University of California, Davis, and Cornell University claims that the combination of ocean-warming and an infectious wasting disease has led to the declined population of these large sea stars.

The sunflower sea star is one of the largest sea star species, they can grow as big as manhole covers. Commonly found in the northwest Pacific, they were once regularly found from Southern California to Alaska and some of the largest sunflower sea stars could be found in Puget Sound, British Columbia and Alaska.

In 2013 and 2014, a disease called sea star wasting syndrome affected around 40 different species of sea stars, including the sunflower sea star, to die off along the North American Pacific coast. Symptoms of the disease would be lesions and tissue decay, which the body structure of the sea star would start to breakdown. For example, their arms may twist and fall off and the sea stars would become limp. Eventually, the sea star would disintegrate and melt away into a white, mushy blob and no longer be a sea star. It is unclear where this disease originated from but researchers believe ocean-warming might be the reason why this disease continues to affect the sea stars and why the sea star population is not recovering fast enough.

Dying sea star

Dying sea star” by Oregon State University is licensed under CC BY-SA 2.0

Ocean-warming is an effect of global warming. The ocean absorbs excess heat from the atmosphere which contains greenhouse gas emissions, which leads to rising ocean temperatures. Increasing ocean temperature can affect many marine species and ecosystems. Warming of the oceans have been linked to the increase and spread of diseases of marine species.

The sunflower sea star species has been detrimentally affected by sea star wasting syndrome. The study conducted by Dr. Harvell and her colleagues collected data over eleven years to show how the population of sea stars have diminished due to this disease. In addition, scientists also found that the ocean water has warmed almost 4 oC within a four-year span in some areas. Results of the study showed the population crash of sunflower sea stars from Southern California to Alaska whilst tracking patterns of unusual warming in the Pacific Ocean. The sunflower sea star is shown to be highly susceptible to this wasting disease because they do not have a complex immune system. As a result, the data showed an 80 to 100% decline over the period of the study.

Sunflower Star Imperiled by Sea Star Wasting Epidemic” by Hakai Institute

If the sunflower sea star dies off, this should be an important indicator of the effects of ocean-warming and its impact on marine ecosystems. Sunflower sea stars are voracious predators in the deep and shallow waters of the northwest Pacific, and if these sea stars were to go away we could see an unbalanced ecosystem in our waters.

– Katherine Lam

Recording the Cell? New technologies further uncover mysteries surrounding the cell.

Does anyone really know what life is like inside of a cell? Sure, we can all say that the mitochondria is the powerhouse of the cell, and we’ve learned mitosis more time than we can count, but do we really know about the intricacies of day to day cellular processes? Historically, answer has been an overwhelming no, but that is something the researchers behind CAMERA are hoping to change.

CAMERA, or CRISPR-mediated analog multievent recording aperture is a tool developed by David Liu and Weixin Tang of Harvard university to record the molecular interactions within a cell, all of which are stored on the cell’s DNA. This new discovery allows scientists to observe and therefore clarify the processes that contribute to such things as the emergence of cancer, aging, environmental damage, and even embryonic development. CAMERA is only one of the many developments based off of the gene cutting technology known as CRISPR-Cas9.

Thyroid Cancer Cell Line. Courtesy of NASA’s Marshall Space Flight Centre and Flickr Commons. 

What is CRISPR-Cas9 you ask? Well, it’s basically a really small pair of scissors, so small that it can even cut DNA. CRISPR-Cas9, or CRISPR for short, is a technology based off of the natural defence mechanisms found in bacteria that have been reengineered for editing genomes. It has the ability to cut the double helix strand of DNA allowing for researchers to easily alter DNA sequences and modify gene expression. Some of the major implications of this include the possible correction of genetic defects, and the treatment and prevention of cancer and other diseases.

Video recreating a CRISPR-mediated genome editing. Courtesy of McGovern Institute for Brain Research at MIT .

So how did scientists develop a cellular recording device from this cutting tool? When CRISPR cuts a DNA strand to alter the sequence, the strand will naturally repair itself but in doing so can occasionally add in errors that make the targeted gene inactive. These random errors can sometimes be used as markers, mapping out the cell’s pattern of differentiation. Liu and Tang took this information and set out to regulate it thereby creating a more detailed, continuous record of a cell’s life, documenting not only its responses to external factors but the severity of the response and how long it lasts.

Flowchart of CRISPR mediated gene alterations. Image courtesy of Flickr Commons

At this point in time, CAMERA, is able to document cellular responses to light exposure, antibiotics, viral infections, and internal molecular interactions in as few as 10 cells. As well, it can record multiple events at once making it an impressive candidate for future medical technologies involved in screening embryos for a wide variety of mutations during development. Despite these impressive feats, Liu and Tang are still working towards pinpointing the recording down to one cell, allowing scientists to one day observe the processes of each cell individually and efficiently isolating any mutations. Another big step is proving it works to the same detailed extent when placed in the body of a living mammal as it does in a small cell group in a petri dish. There is still a lot to be done before we can confidently say we know how cells operate but CAMERA is a step in the right direction.

-Tenanye Haglund

No Snow On Date Night

A speck of white twinkled as it fell across the night sky, silent as it danced in the cold wind. She smiled in willful ignorance, praying what she had seen was impossible. Her head tilted, shoulders twitching in anxiety, hoping the one across from her had not noticed. Meanwhile, he felt the itch too, terrified as he glanced at the light fluff drifting onto the table before returning an anxious gaze. The winter was cold, snow was inevitable, but alas… no snow was forecasted for the next week. This is the tragedy of two consenting more than friends trying to figure it out, and their mutual but private battle with an affliction affecting 50 percent of all humans. This is dandruff.

What is Dandruff

Although these white flakes are most noticeable in your hair and on your clothes, dandruff isn’t really a hair condition but is actually due to your scalp. Naturally, your body produces skin cells constantly, and as they travel to the surface of the skin, the epidermis, the old cells fall off. For most, these cells are too small to be noticeable, but for others, when these cells clump together they can be rather large. These larger clumps of dead skin cells are commonly referred to as dandruff.

A woman struggling with dandruff @artem_goncharov

What Causes Dandruff

Dandruff affects about 50% of the population and the exact cause of it is actually unknown. Although, in recent studies, the yeast, Malassezia, is found to play a role in producing dandruff. When reducing the population of Malassezia in the scalp, amounts of flakes have been found to improve. But what is Malassezia and what does it do? Malassezia is a fungus that lives on the scalp where it, unfortunately, happens to be an ideal environment for it to survive. Here it releases enzymes that metabolize fat molecules, this produces oleic acids that are found to irritate the scalp. As a defense mechanism, your scalp can increase the rate it produces skin cells, sometimes causing a months worth of skin cells to appear on the surface in time frames as short as seven days.

Treatments for Dandruff

Many shampoos advertise being good treatments for dandruff but the ideal shampoo should contain anti-fungal or anti-yeast ingredients. A few common examples, found in Selsun and many other anti-dandruff shampoos, are zinc pyrithione and selenium sulfide which have the property of slowing down the growth of yeasts. When used in shampoo’s these ingredients are found to aid in reducing the increased production of skin cells by slowing down the metabolism of Malassezia for people that are dandruff-prone. 

The video, “Dandruff | How To Get Rid Of Dandruff (2018)” by AbrahamThePharmacist, below basically sums up everything I’ve gone over with the exception of stating that Malassezia is the main cause of shampoo as literature states that there is limited research stating such. 

 

Conclusion

Although we don’t have either confident cause or a concrete solution to dandruff, in using shampoos with anti-fungal ingredients this embarrassing condition can be minimized.

-Nelson Bulaun