Author Archives: karlys4

Oregano, Grapes and Cancer – Oh my!

With November here, most people are aware that “Movember” is also in full swing, promoting prostate cancer research, among other things. What isn’t so common knowledge is the fact that two rather yummy research endeavours are showing promise in the field of prostate cancer treatment.

Oregano – photo from Fernando Stankuns via Flickr

Already well known for being an antioxidant, oregano was used in one study to test its effects on prostate cancer cells. Researchers tested carvacrol, a component of oregano, in varying concentrations against human prostate cancer cells for different time intervals. Amazingly, they discovered that the carvacrol completely wiped out the cancer cells!

From their research, the team found out that the carvacrol actually caused apoptosis, or ‘cell suicide’, in the cancer cells. It is still in its beginning stages but “if the study continues to yield positive results, this super-spice may represent a very promising therapy for patients with prostate cancer,” says Dr. Bavadekar, the lead researcher. Watch here as the SourceFed team talks about this new research:

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The next study looks into the effects of a compound found in red wine and grape skin on prostate cancer cells. Previous studies have shown that this compound, resveratrol, may have health benefits concerning heart health and stroke prevention. In this study, researchers found that the compound caused the prostate cancer cells to be more vulnerable to radiation. Watch here as the MU News Bureau talks to the researchers about their discovery:

 

Red Wine – photo from Emiliano De Laurentiis via Flickr

The resveratrol causes the cancer cells to express two proteins, perforin and granzyme B, which work together to cause the cell to weaken. When combined with radiation, more cancer cells were killed than with just radiation alone.

The drawback to this discovery is that the body metabolizes resveratrol very efficiently. This means that a very high dosage would need to be consumed in order for the compound to be effective at the tumour site. Due to this, researchers are looking into alternate delivery methods, as the treatment is otherwise promising.

I believe that both of these studies show a lot of potential and are particularly interesting because the compounds used are naturally occurring. It makes me wonder about all the other naturally occurring treatments that may still be out there. Who knows, maybe the next promising cancer treatment will be from pomegranates or blueberries!

-Karly Stillwell

I am deadly, see me flash!

Found hiding under rocks and in shells along beaches from Japan to Australia, the blue ringed octopus, Hapalochlaena lunulata, is one of the most beautiful creatures in the waters; but, it’s appearance can be deceiving as it is also one of the most deadly octopuses in the world.

Photo from CirclesOfLight via Flickr

These small octopuses are only the size of a golf ball but their bite contains a strong neurotoxin with the ability to be fatal to an adult human. When resting, they appear yellow in colour with brown spots; however, when provoked, they exhibit about 60 bright blue rings that cover their body.

Most octopuses utilize three structures when demonstrating colour change of their skin: chromatophores, iridophores and leucophores. Chromatophores are sacs in the skin, filled with pigment and controlled by the surrounding muscles. Upon contraction or relaxation, the sacs shrink or expand to change the look of the pigment. Iridophores are iridescent sheets located beneath chromatophores that are controlled by the shift of proteins and cytoplasm. This results in the sheets reflecting different wavelengths of light or UV rays to change the sheet’s appearance. Lastly, residing under iridophores, leucophores reflect white light to give contrast to the other colours from the chromatophores and iridophores.

Photo from Steve Childs via Flickr

Recently, researchers have found that this typical method of visual display is not how the blue ringed octopus warns its prey. The rings on this small octopus are made of iridophores with no chromatophores above them; instead, the chromatophores were located beneath and surrounding the rings. To give its warning, the octopus relaxes the muscles above its rings and contracts the ones surrounding it, exposing the iridescent blue of the iridophores and dark pigments of the chromatophores. With the iridophores on clear display and chromatophores surrounding, the blue ringed octopus is able to employ an impressive and vivid warning signal as seen below:

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As impressive as this display is, it is also very effective. The blue-green section of the visible spectrum is seen by most of the predators interested in eating these octopuses and it is vivid in underwater light. The speed at which the display is activated combined with the bright colour proves beneficial for both predator and prey as the predator is warned before it attacks the deadly octopus and the octopus survives to live another day.

The defensive nature of this small creature just goes to show that appearances can be deceiving – even the most beautiful of creatures can be deadly.

 – Karly Stillwell

When in doubt, throw it out!

You’re up late studying for midterms, desperately trying to avoid blinking for fear of falling asleep. As a quick pick-me-up you reach for a piece of Halloween candy. You open the wrapper and in your sleep-deprived state, your candy falls to the floor. According to an old wives tale, you have approximately 3-5 seconds to grab your tasty treat before it becomes covered in bacteria and whatever else might want a bite. Your candy is sitting on the floor, helpless. Regardless of whether it’s two seconds after you dropped it or six, you pick it up. Apart from the stray fluff from your fuzzy socks, it looks relatively unharmed. Now, the big question: do you eat it?

According to researchers, the answer is a resounding NO. Bacteria and other microorganisms immediately contaminate food that falls to the floor. There are some factors to take into account but in general, it is safer to ditch the dropped food. This is why some researchers think we should be using a ‘when in doubt, throw it out’ philosophy as opposed to the mythical ‘five second rule’.

Two factors that determine how many bacteria end up on your food are the moisture content of the food and the cleanliness of the surface upon which it falls. Moist food, such as cheese or meat, is quite easy for bacteria to stick to and ends up with higher bacteria contamination when dropped. Bacteria have a more difficult time with dry food, such as crackers or cookies, which don’t become contaminated as easily. As for the surface in question, obviously a cleaner surface will have less bacteria and a lesser chance of contaminating dropped food. Watch here as Dr. Philip Button outlines his take on these two factors:

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But what about the length of time food is left on the floor? It has been shown that the difference in amount of bacteria on food that was left for two seconds or six seconds is not significant. If bacteria are there, they are going to be on that food faster than you can react.

And what about wiping it off? Or rinsing it with water? Once food has been dropped or has touched something it shouldn’t, there is really no way to get it back to its original state. Wiping or rinsing may get rid of some bacteria, but it cannot get rid of them all.

So if you drop a piece of dry food on a clean surface, what’s the big deal? As clean as the surface may be, you don’t really know which bacteria are present. The bacteria that end up on the food may require only a small number of organisms to be present in order to cause disease, which could be costly for someone with a weak immune system.

The next time you drop a piece of food on the floor, think about the circumstances under which it is falling and who will be eating it. Remember: when in doubt, throw it out!

-Karly Stillwell