Tag Archives: 3D Printing

Move over, 3D Movies. 3D Printing is the New Trend.

Do you remember the quote “You wouldn’t download a car”? It was the message that accompanied the dark, serious commercial on piracy. But with the wonders of technology, something like that is actually possible as silly as that sounds. How? 3D printing.

3D printing has been around since the 1980’s but has really started to take off more recently in the 2010’s due to a reduction in price and availability of the 3D printer. Although the 3D printer shares its name with the commonly used 2D computer printer, they are fundamentally quite different as the 3D printer prints out material in layers, one over another. Due to the versatility of the 3D printer, science has been utilizing 3D printers in a wide variety of ways, and this progressive stance has made an impact on many fields.

Regular 3D Printer (Photo by: Eva Wolf, Source: WikimediaCommons)

One example of science’s venture into 3D printer comes in the form of medical science, as 3D printer allows for the creation of things like the human liver. Obviously, the 3D printer doesn’t just magically make a kidney appear out of nowhere, so how does it do it? The San Diego Company, Organovo has been making a great deal of progress on it, and they are doing this by printing out a mass of human cells which can be thought of as the ink. These human cells cluster to form structures, before adding another layer. These layers eventually fuse to form the 3D shape of the organ.  Although that description is a bit simpler than what actually happens, it gives a brief idea of how it is done.

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Another way science has been utilizing 3D printers is in a field like marine-ecology. 3D printers are capable of recreating coral reef that can be placed into damaged marine ecosystems. These artificial coral reefs provide a source of habitat and helps improves the health of marine life there. This is exactly what is happening in the region of the Persian Gulf, an area where overfishing has been negatively impacting the ecosystem there. The use of artificial reef is bringing back balance back into the area.

Coral Reef (Photo by: Nick Hobgood Source: WikimediaCommons)

Those two examples give just a quick glimpse of what 3D printing can do and although it isn’t too widespread at the moment due to the price and the tech of the 3D printer. Over time, as price decreases and tech goes up, 3-D printing will continue to make its mark on science.

– Jeffrey Chen

Printing the Sum of Our Parts

You don’t have to know anyone with a failed organ to understand what kind of stress they must go through while they’re on the organ transplant waiting list.  Many don’t live to see the end of that line-up and heartbreakingly, the ones who make it are still at danger from organ rejection. Thankfully, a solution is on the horizon. In the near future, all a patient has to do is wait for their kidney or liver to be printed, 3D printed that is.

You may have heard a thing or two about 3D printers, the method of manufacturing an object, layer by layer, guided by a digital model of what you wish to print.  While it may seem complicated enough to print plastics or metal into complex shapes, scientists and engineers are now working on creating ways to print fully functional organs.

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We’ve had the ability to print tissues (hyperlink) made of a single type of cell for some time now, but the possibility of producing entire organs is now on the horizon, most notably, the human liver.

Organovo-3D-Printed-Liver

However, there are still many major milestones to reach before the first printed organ can be transplanted to a donor.  Currently, the greatest tissue thickness that can be printed is about a centimeter; adding more layers causes the tissue to suffocate from lack of oxygen and nutrients. Only once a way to incorporate blood vessels into the tissue is developed will there be serious talk of transplantation.

Nevertheless, we are already beginning to reap the benefits of these techniques. The thin pieces of functioning liver tissue are being used as ‘organs on a chip’  in testing new drugs. This means we can finally begin moving away from animal testing, without sacrificing reliability of animal models. In fact, such ‘organs on a chip’ save money and resources for medical research. Finally, something both PETA and pharmaceutical companies can be happy about.

As for clinical applications in humans, the current state looks rather disheartening; so far, only 3D printed implants have been used. However, for the thousands currently in line for a transplant, this technology offers reason to hope.

 

Published by Alena Safina