Tag Archives: Brain

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Synesthesia, a Real-life Superpower

Have you ever wanted to have night vision, or Clark Kent’s super-hearing? Although those particular powers may be firmly set in the realm of comic books, there are real people in the world with what many describe as a special ability; synesthesia.

Synesthesia is a phenomenon where one stimulus triggers two or more of the areas of the brain that deal with processing sensations. Basically, synesthetes (people who have synesthesia), have the sensation of tasting colors, seeing music or experiencing other, even more amazing examples of the blending of perception. A synesthete may taste raspberries just from seeing the color blue, or vice versa!

There are many different types of synesthesia, however the most prevalent is grapheme-color synesthesia, which means that someone associates color to a particular letter.  Patricia Lynn, a writer and a famous synesthete, explains how she sees text:

“For as long as I could remember, each letter of the alphabet had a different color.  Each word had a different color too… and so did each number.  The colors of letters, words and numbers were as intrinsic a part of them as their shapes, and like the shapes, the colors never changed.”

How synesthetes with grapheme – color synesthesia might see these letters.

Besides being a cool get-to-know-you fact, synesthesia can have practical benefits. Patricia explains how synesthesia helped her learn her letters as a child: “[To] make an ‘R’, all I had to do was first write a ‘P’ and then draw a line down from its loop. … I was so surprised that I could turn a yellow letter into an orange one just by adding a line,”.  Other perks include having a better memory for certain tasks, or identifying musical notes more easily thanks to this biological quirk.

Like many other synesthetes, Patricia went a large part of her life without knowing that the way she saw the world was unique.  This fact has somewhat impeded our ability to study what is going in the brains of people with synesthesia; potential subjects don’t know that they are different from others.  Worse still is that just a few decades ago, those who actually realized they could feel what others didn’t would be labeled as having an overly-active imagination. Knowledge about this phenomenon was just too niche and most did not believe that this is how synesthetes legitimately saw the world.

Thankfully, that’s changed in the past few decades. We now have a better understanding of what is happening when, say, a dog barking sets of a display of fireworks in the mind of the synesthete. In the average brain, all the major regions are quite predictably interconnected; our functional networks are hooked up to give us the every-day perception of reality (how dull!). One theory states that unlike us, people who have synesthesia have significantly greater connectivity  between two or several of their perceptual centers .  Say, a person who experiences music as sensations in their body would have a greater amount of connectivity between the auditory and somatosensory (the part that processes touch) centers of the brain. How this occurs is still mostly a mystery.

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Steffie Tomson (Synesthesia Researcher) [Creative Commons attribution licence]

Although almost all synesthetes are born with their ability, there have been incidents of people getting synesthesia as a result of brain trauma. Although I would love to see  songs give me a personal visual display when I go dancing, I don’t think I’d ever resort to such extreme measures.

 

Written and published by Alena Safina

 

It’s in the Blood

Breakthrough research was published on March 9th 2014 by Dr. Howard Federoff and a team of researchers in Washington DC. They developed a blood test that identifies 10 biological markers which has been shown to determine if healthy individuals will develop Alzheimer’s Disease within two or three years. This amazing stepping stone could help individuals receive treatment before developing symptoms of this horrible neurodegenerative disease.

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35 million people all over the world have been diagnosed with Alzheimer’s, the most common form of dementia, and this number is rising rapidly. The ripple effect of this disease touches many family members by having to care for them or put them in care-homes. Individuals with onset Alzheimer’s disease become confused, frustrated, and forgetful and eventually progress to where they cannot talk, feed, or even dress themselves. Alzheimer’s is a horrible disease affecting many innocent elderly people and hopefully in the near future, there will be tremendous progress in the treatment of Alzheimer’s; it may just start before symptoms even begin.

Visual representation of Alzheimer’s (Shuttershock)

“This is a very exciting time,” says Federoff, who leads the team. He states that the test could help patients at risk of developing Alzheimer’s disease and perhaps delay or even stop the progression. “We don’t really know the source of the ten molecules,” admits Federoff, but he suggests that they reflect the destruction of neurons in the brain, which ultimately leads to cognitive impairment and Alzheimer’s disease. When neurons are destroyed in the brain, they cannot come back online or be built again.

Simon Lovestone, a University of Oxford neuroscientist is also excited about the findings in this study. “We desperately need biomarkers which would allow patients to be identified – and recruited into trials – before their symptoms begin”, says Lovestone, who is also a coordinator of a European public-private partnership that searchers for new biomarkers for Alzheimer’s.

Blood Vials (Flickr: loscheiner)

Previous studies have emphasized treatment after diagnosis of Alzheimer’s disease, but no one has ever been completely cured. This new and important research uses blood that is easily accessible, and it has the ability to identify potential risk factors before any symptoms arise. Stopping the disease before it even happens could be an incredible advancement in this field.

Federoff highlights that larger studies must be done exploring a more diverse range of individuals including different races and ages. When these large-scale studies show positive results, perhaps early diagnoses can prevent the disease from becoming aggressive and debilitating to controlled and stable. Overall, this is very promising research that I see possibly flooding the medical field.

By Danielle Marcoux

Sources:

  • http://www.nature.com/news/biomarkers-could-predict-alzheimer-s-before-it-starts-1.14834
  • http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3466.html
  • http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp
  • http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-medications-fact-sheet
  • http://www.webmd.com/alzheimers/guide/treatment-overview