Category Archives: Biological Sciences

Link

Robots build after cockroaches will save lives

Robots build after cockroaches will save lives

Cockroaches. They are not nice or fluffy and spotting them indoors means trouble. In our minds, cockroaches are associated with mold, dirt, and cavity and they are in fact suitable carriers for diseases such as E-coli and salmonella. However, behind its repugnant appearance there is one of the most fascinating creatures living in our environment.

They are thought to be the world oldest pests and legend has it that they will survive the nuclear apocalypse. During their long evolutionary history, cockroaches have developed high degrees of resistance to environmental risks. Their population experiences a rise in the hot seasons and despite the efforts of pest control companies, cockroaches often become gradually resilient to pesticides.

25859665686_b207b4c0c3_b

cockroaches can stand pressure up to 900 times their weight

The extraordinary physique of the cockroaches have inspired scientist in developing robots that can potentially save many lives. The flexible nature of cockroaches’ bodies enables them to swiftly squish throw crevices of only two pennies (one tenth of an inch) wide. Researchers at the University of California, Berkeley have produced a prototype robot modelled after cockroaches’ physique that can be released into the cracks and vents of rubbles after an earthquake to quickly locate survivors.

2768539094_b0952577f0_b

Cockroaches’ locomotive abilities let them move as fast as five feet per second, allowing them to squish through gaps and cracks by reorienting their legs to one side. Moreover, cockroaches are highly resilient against extreme pressure and they can stand up to 900 times of their body weight. This enables cockroaches to survive crashes under the rubble, making them strong and yet agile. Robots designed by researchers at UC Berkeley, which were modeled after cockroaches, were named CRAM for compressible robot with articulated mechanisms. The shell of the robot can be compressed by up to 20 lb and its unhinged legs allow it to move under compression.

 

So cockroaches amazing capabilities are not only inspiration for urban myths, they inspire scientists, too.

 

Sadaf Yadegari

Why haven’t we found HIV vaccine yet?

In 1984, after the cause of AIDS was discovered, US Health and Human Services Secretary announced that a vaccine for HIV would be available in two years time. Three decades later, more than eighty clinical trials and over thirty prospective vaccines to date, the virus is still winning!

Why is it such an impossible task to create an effective vaccine against HIV? A task that seems to have disheartened many researchers from striving to find the solution to a persistent pandemic! Without a cure for AIDS, a vaccine is the only way to slow it down; it has wiped out over 30 million people world wide and has over 34 million people currently living with HIV. Therefore, with millions of dollars being allocated to HIV vaccine research annually, why is a breakthrough still lacking?

Normally, vaccines are composed of a harmless form of the virus or parts of it such as surface proteins; these stimulate immune cells to produce compounds known as antibodies that bind a small part of the virus component called an epitope; the attachment deactivates the virus preventing it from invading healthy tissues and causing disease. Vaccines also activate immune cells that kill infected cells.

However, this type of vaccine, successful in controlling more than 30 most contagious illnesses, is defective when it comes to HIV. This is because HIV, like the common cold virus, undergoes numerous errors when replicating it’s DNA. Therefore, HIV’s epitopes are very prone to changing. Due to the high specificity of antibodies and “killer” cells, viruses that have changed epitopes cannot be deactivated by the same antibodies and “killer” cells. This property of HIV makes it very challenging to create an effective vaccine. Despite being weakened, using live HIV as a vaccine is also gravely concerning; it could possibly evolve into a virulent form as the virus is constantly mutating (changing). HIV particles are also by nature very different despite being incredibly mutable. This is because they descend from numerous ancestors. For an effective vaccine to be created, its breadth should be large enough to account for all HIV variants.

Another setback in the development of HIV vaccine is the fact that AIDS recovery is rare; vaccines are usually geared to mimic the immune response generated by our bodies after infection and recovery from the subsequent disease. In the case of HIV, the body cannot develop this immunity as HIV attacks immune cells. Lastly, HIV integrates its DNA with ours and becomes a part of us! This gives “killer” cells a hard time detecting infected cells where virus assembly takes place. These factors among others are what have stalled HIV vaccine development. But that does not mean a vaccine is impossible.

Despite the difficulties, no need to worry! We all possess an intangible, non-medicinal vaccine that undoubtedly has the highest success rate in preventing HIV infections so far; the will to take preventative measures as HIV isn’t easily transmissible. Learn more on how to protect yourself here.

-Jane Wanjiru

Cutting too quick?

In 2015 the number of cesarean sections (c-sections) were at a whopping 32% of all births- this is almost double the number of c-sections performed in the 90’s! It is important to note that the risk factors that warrant doctors to perform an emergency c-section are not also on the rise. C-sections are being more and more often performed on low risk pregnancies, inherently putting both baby and mom at a higher risk of complications. The graph below show’s the maternal morbidity rate of women by method of delivery. It is evident that c-sections have a much greater risk than vaginal births!

screen-shot-2016-10-11-at-7-00-52-pm

So if risk factors leading to c-sections are not on the rise and a c-section puts a mother at a higher risk of complications, why is the prevalence of c-sections so high? Lets take a look at some of the possible reasons:

Technology Electronic fetal monitoring begins once a pregnant woman enters the hospital. It tracks the babies vitals and can detect signs of distress. As the only way to really assess the babies safety, it’s a great tool. However, there isn’t extensive research on how to interpret the readings and there are many false positives, leading to more c-sections than probably necessary.

Decline in VBAC V-what? Vaginal Birth After Cesarean. Once a woman has her first cesarean birth- warranted or not-  there are complications involved in a subqequent vaginal birth. This means that a mother who delivers via cesarean will most likely have to deliver by c-section for all subsequent births. This is a positive feedback loop, definitely contributing to the rise in c-sections!

Control  Usually women have the choice of which birthing method they prefer. For some, it is as simple as wanting to choose the day and the doctor that delivers their baby- control only a c-section can give you. While this should still be taken into account, it probably isn’t a huge contributor to the rise in c-sections, as  a recent study found that only 10% of all c-sections were elected procedures.

Commercialization Is it possible that society is turning the most basic and beautiful reproductive right into a business? In a recent study – whose results are shown in the graph below-  it was found that the majority of c-sections occur from Monday to Friday between the hours of 8am and 5pm. Hmm… that’s convenient.  Could the number of c-sections be on the rise because the labor and delivery doc wants to get home in time to eat dinner?

screen-shot-2016-10-10-at-5-52-47-pm

Regardless, it is important that a woman knows her options when she is in the delivery room and it is equally as important that doctors are making the best choice on behalf of the mother, who is in arguably her most powerful and vulnerable state. Whatever factor, or more likely combination of factors, is responsible for the increase in c-sections, it is critical that we don’t lose sight of the most important thing: the safety of both mother and baby.

-Steph Schaupmeyer

The Solution is Sugar!

The farming industry requires an immense amount of labor and money. However, there are many factors that come into play when producing a healthy crop. Focusing on rice agriculture, examples of harmful disease that cause loss of crops are blast and brown spot.

Blast disease is the most important disease that has been affecting rice crops worldwide. This disease infects rice crops by creating lesions on different parts of the plant, such as the leaves, seeds and even roots. The lesions lead to cell death and eventually cause death of the leaves and entire plants. The following video demonstrates the impact of the rice blast disease.

Credit: This Week in Louisiana Agriculture, YouTube.

So, what is being done to protect crops?

Since rice crops are a predominant food source for a vast population around the world, it is important to keep these crops healthy. One method of controlling disease in rice crops are fungicides, however, they sometimes have negative effects on the environment and human health. For example, the fungicide Mancozeb creates concerns in human metabolism and respiration.

Fungicides are not a long-term solution! Pathogens are able to become resistant to fungicides overtime and infect crops. The production and use of fungicides is costly and to have them become ineffective is a waste of both time and money. Due to these effects, research is being conducted in order to find substitutes for fungicides.

What have researchers found?

One solution is sugar! Chitosan specifically, is a sugar that can be found naturally in the shells of crustaceans and is renewable.

Could Chitosan be the solution to the long-lasting issue of using fungicides in agriculture?  The most important benefit of Chitosan is that it is naturally present in the environment and therefore is not as harmful as using chemicals. Secondly, Chitosan is abundant, accessible and not nearly as expensive as producing chemical fungicides — which are only short-term solutions.

How does Chitosan work?

Chitosan possesses properties that help protect plants and promote antifungal behaviour. A study proposed that Chitosan inhibits the access of fungi to essential nutrients of plants, preventing the growth of fungi.

Another study concluded that Chitosan modifies the outer membrane of pathogens, destroying their ability to attack plants and therefore making crops less susceptible to fungal virus and disease. Along with preventing fungal disease, Chitosan also activates defense mechanisms in plants. The dual action of Chitosan makes it an ideal substitute for fungicides.

Is Chitosan a long term solution?

I believe that the Chitosan solution definitely has benefits such as, being renewable and inexpensive but it should be tested extensively to prove success. Research has shown several qualities of Chitosan such as antimicrobial properties against viruses, bacteria, fungi and insects, which further confirm it as a good solution for protecting rice crops. Despite these findings, Chitosan should be tested thoroughly before being put into practice to avoid putting crops at risk of failure.

Pavneet Virk

32 Pearls

If not the hardest, teeth are one of the most solid parts of the human body. There are four different types of teeth in our oral cavity (Figure 1) including incisors, canines, premolars, and molars. Both individually and as a collective they are responsible for many different functions in the human body.

illu_mouth

Figure 1, Oral Cavity

https://en.wikipedia.org/wiki/Mouth_assessment

The main function of teeth is mastication. When we eat food, our body should process it and make it ready for digestion, and the first step in digestion is to break down the food by teeth into smaller pieces. Incisors usually cut the food, then canines with some help from premolars tear it, and at the end premolars and mainly molars grind the food and make it ready for swallowing. Without our teeth, we would not be able to fulfill this critical function, which would as a result lead to many problems with digestion.

The second function of teeth is that they aid in pronunciation. In other words, they help us to pronounce words properly. As we grow up, we learn to pronounce with the use of our teeth and the help of our tongue. Those who lose all or some of their teeth cannot pronounce the words accurately so will have serious problem in speaking.

cc7333d9fe3c092da806bda4bea27ae2

Figure 2, Facial Muscles

https://www.pinterest.com/pin/468022586248651317/

Teeth also have a direct influence on our appearance, therefore they have an important aesthetic function. Teeth support the facial muscles (Figure 2)and other tissues around them, thus the shape and form of our face depends, to a great extend, on our teeth. Having clean and normal teeth will create a nice smile, and it can have direct influence on the personal and professional life of every individual. For example, possessing a nice and beautiful smile has direct impact on professional life of many celebrities.

https://www.youtube.com/watch?v=uHUyg94JSkg

It is clear that teeth have an important role in our lives, and it is beneficial to take care of them as they are as precious as pearls (Figure 3).

white-teeth1

Figure 3, Teeth

http://treeoflifehealthcoaching.com/service/blog/2016/05/10/teethwhitening