Tag Archives: immunology

Global Warming… and Smallpox?

    Heatwaves, droughts, freaky weather, and rising sea levels are just some of the extreme consequences we can expect as global temperatures continue to rise over the next few years. However, according to some scientists, we can add another potential disaster to that list: the introduction of new diseases.

    Researchers based in France and Russia retrieved and analyzed a 30,000 year-old permafrost core, in which was contained a sample of giant DNA viruses. These are viruses that are so big that some are visible underneath light microscopes. This giant DNA virus, which the researchers named Pithovirus sibericum, is believed to have been last active during the previous Ice Age.

The Chukotka region of Sibera, where the permafrost core was taken from. (Source: Wikipedia)

    Researchers were able to bring the sample “back to life” in the lab and believe that its protein coat was a factor in protecting it and ensuring that it could tolerate 30,000 years of being encased in permafrost.

 

    Although this virus only infects amoebas and is therefore harmless to humans, this does have grave implications for people: as permafrost begins to melt across the globe, more viruses with the same protective coating could be introduced again. Some of these viruses may in fact be able to infect humans and we may likely immunity to them (seeing as some have disappeared into the ground before Homo sapiens eventually came about).

Microscopic image of Pithovirus sibericum. (Source: Julia Bartolia and Chantal Abergel of UGS and CNRS-AMU)

    One concern expressed in the comments section is smallpox: although the last case of smallpox was in 1977, many smallpox victims of the 1800’s were buried in northern Canada, where they are encased in permafrost. As temperatures continue to rise and ice continues to melt, many of these bodies may be exposed to the surface. Could smallpox survive? Hopefully not. But in a worst-case scenario, we could see the re-emergence of smallpox and although it would be relatively brief (because of our access to vaccines), it would still be devastating to many.

    However, people must be wary of these alarmist attitudes. For example, we don’t know how likely it is that smallpox could survive. Even if it could, could it be re-animated? Pithovirus sibericum needed the help of a lab to start functioning again. So even if these viruses were exposed to the surrounding environment, could they function and infect people? The ability to infect people is an adaptation: many of these viruses would be older than us, so how would they have to ability to infect humans?

   Global warming is a frightening thought, but we don’t need to scare ourselves silly thinking about things that may be more suited for the script of a science fiction movie.

 – Nicholas MacDonald