Author Archives: Matthew Lim

Napping = Lazy?: The Genetics Behind Afternoon Naps

Most humans spend around one-third of their lives sleeping. However, the word “nap” has negative connotations of laziness and lack of self-discipline because of the busy and competitive nature of the current world. The loss of daytime productivity because of naps often leads to self-criticism and loss of self-confidence, which forms the perspective on naps as a waste of time.  Research has discovered that your genes control your desire for daytime naps, and you may be at a significant disadvantage if you love daytime naps.

The Genetics of Nap-Lovers

On contrary to the public perception that environmental or behavioral choices determine the desire for daytime naps, those desires are biologically driven by genes. It’s true that whether we take a daytime nap or not depends on our choices. However, recent research (2021) identified 123 regions in the human genome that are associated with daytime napping. For example, mutation of the genes associated with the production of orexin, a brain chemical that regulates wakefulness, explains why some people nap more than others. Therefore, these nap-promoting gene variants drive daytime naps, not the laziness of the nap-lovers. 

However, that does not mean that there are no disadvantages to these gene variants. Aside from the loss of daytime productivity, the researchers found that some of the gene variants that promote naps have a connection with health risk factors. They found that the nap-lovers generally have larger waist circumference and higher blood pressure compared to those that don’t take naps. 

 

The Genetics of Super Sleepers

On the other hand, another research (2019) discovered the gene of “super sleepers,” a rare breed of humans that requires a shorter duration of sleep. They found that individuals who had inherited an extremely rare gene named DEC2 only require around six hours of sleep per night for full recovery from fatigue. Also, the researchers claim that the super sleepers do not suffer any adverse health effects of chronic sleep deprivation such as cardiovascular disease, cancer, and dementia; instead, they tend to be more optimistic, energetic, and even have a longer life expectancy.

Fortunately, as much as it seems unfair, further studies on super sleepers may help the general population overcome their complications concerning sleep. According to Dr. Ying-Hui Fu, a professor of neurology at the University of California, the sleep quality and efficiency of super sleepers are naturally better; thus, the advantage in health and no need for naps. By analyzing how DEC2 induces superior sleep quality, the researchers anticipate resolving sleep disorders for normal sleepers and optimize their sleep efficiency.

Recommendation for Nap-Lovers

Health professional recommends daytime naps of around three times a week; however, you may want to suspect the quality of your nighttime sleep if you desire naps every day. Although the disadvantages mentioned above may not be happy news for nap-lovers, you must acknowledge the disadvantage and pay more attention to your sleep schedule and health.

Here’s an informative video on daytime naps to end off:

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-Matthew Lim

Forgot Something? Suspect Your Dopamine

You open up an internet browser, but you forget what you were going to search for or why you even started your computer. Have you ever came across these situations?  The recent research on temporary memory loss (2021) has discovered the betrayer within our body: the dopamine.

Dopamine has a reputation as the “happy hormone.” It’s a neurotransmitter, a substance that conveys signals between the neurons that mediate pleasure in our brain and make you crave for the things you love. For instance, you constantly refresh your Instagram feed or click on the next recommended video on YouTube because your brain remembers and relate those activities to pleasure. Then every time you perform those activities your brain release dopamine, which makes you feel good.

Problems with Dopamine Addiction

In a nutshell, dopamine acts very similar to recreational drugs because it constantly tempts and controls you to do things that provide instant gratification and make you crave for stronger pleasure. The problem of dopamine addiction recently arose because of the rapid technological advancement, which allowed for easy access to activities that release dopamine such as social media, video games, and pornography. People have hard time focusing on their work and managing their time because they crave that dopamine shots.

Here’s a video that talks about the effect of dopamine on human and possible solution to overcome addiction:

YouTube Preview Image

Source: TopThink (youtube.com)

In addition, the researchers from Scripps Research Institute revealed dopamine’s another dark secret. They discovered the mechanism in which the stimulation of dopamine circuit is responsible for transient forgetting, also known as temporary memory loss. In particular, the biochemical team specified a single pair of dopamine-releasing neuron, named PPL1- α2α’2, that causes the universal nuisance in our brain.

In summary, the research team trained Drosophila, commonly known as the fruit fly, to associate a certain scent with an unpleasant shock. However, when the flies were introduced to stimuli such as a puff of air or blue light, the type of light emitted from the screens of your electronic devices, the dopamine released due to the stimuli interfered with the flies’ memory signal and the flies temporarily forgot the negative association with the scent.

Furthermore, the research found that the increased strength or intensity of the stimulus increases the duration of the temporary memory loss . In other words, exposure to stronger stimulus, such as illicit drug or concentrated alcohol, requires more time to recover from the transient memory loss.

During the unprecedented period of pandemic, without social interactions, you probably consume more social media feeds or YouTube videos for your daily dose of dopamine. However, think of dopamine as sugar for now. Your body needs it to continue the happy life, but addiction could bring potential complications with regards to your success and health. Experts recommend activities such as the dopamine detox or meditation to overcome the dopamine addiction. Control your dopamine; don’t let the YouTube recommendations control you!

-Matthew Lim

Forgot Something? Suspect Your Dopamine

You open up an internet browser, but you forget what you were going to search for or why you even started your computer. Have you ever come across these situations?  The recent research on the temporary memory loss have discovered the betrayer within our body: the notorious dopamine.

Dopamine has a reputation as the “happy hormone.” It’s a neurotransmitter, a substance that conveys signals between neurons, that mediates pleasure in our brain and makes you crave for the things you love. For instance, you constantly refresh your Instagram feed or click on the next recommended video on YouTube because your brain remembers and relate those activities to pleasure. Then every time you perform those activities your brain release dopamine, which makes you feel good.

Social Media and Distractions

Source: Fauno (pixabay.com)

Q: Sounds good! Everyone loves pleasure and happiness! What’s the problem?

A: Humans are not supposed to feel pleasure every time. In a nutshell, dopamine acts very similar to recreational drug because it constantly tempts you and controls you to do things that provides instant gratification and crave for stronger pleasure. The problem of dopamine addiction recently arose because of the rapid technological advancement, which allows for easy access to activities that release dopamine such as social media, video games, and pornography. People have hard time focusing on their work and managing their time because they crave that dopamine shots.

Here’s a video that talks about effect of dopamine on human and possible solution to overcome addiction:

YouTube Preview Image

Source: TopThink (youtube.com)

In addition, the researchers from Scripps Research Institute revealed dopamine’s another dark secret. They discovered the mechanism in which the stimulation of dopamine circuit is responsible for transient forgetting, also known as temporary memory loss. In particular, the biochemical team specified a single pair of dopamine-releasing neuron, named PPL1- α2α’2, that causes the universal nuisance in our brain.

Source: Tumisu (pixabay.com)

In summary, the research taught Drosophila, the common fruit fly, to associate certain scent with unpleasant shock. However, when the subject was introduced to interfering stimuli such as a puff of air or blue light, the type of light emitted from the screens of your electronic devices, the dopamine released due to the stimuli interfered with the flies’ memory retrieval signal and the flies temporarily forgot the scent’s negative association.

Furthermore, the research found a positive correlation between the strength of the stimulus and the lasting period of memory loss. In other words, exposure to stronger stimulus, such as illicit drugs or concentrated alcohol, require more time to recover from the transient memory loss.

During the unprecedented period of pandemic, without social interactions, you probably consume more social media feeds or YouTube videos for your daily dose of dopamine. However, think of dopamine as sugar for now. Your body needs it to continue the happy life, but addiction could bring potential complications with regards to your success and health. Control your dopamine. Don’t let YouTube recommendations control you!

-Matthew Lim