Category Archives: Biological Sciences

Baby Sharks Face a Gloomy Future

Sharks are considered the lions of the sea but due to climate change they are losing their glory. With global warming causing the rise of ocean temperatures one particularly tough and beautiful species, the epaulette shark sometimes referred to as the walking shark, may be heading towards disaster.

An Epaulette Shark

An Epaulette Shark: Source: flickr.com/Richard Ling

The epaulette shark lives in the Great Barrier Reef in Australia and finds its food in shallow puddles between the coral. This shallow environment is dangerous and would leave most fish stranded out of the water left to cook and die under the sun. This amazing animal is not so easily defeated and is able to preserve its breath and march back towards the sea.

Video Source: Nature on PBS| Youtube

The epaulette shark has proven itself to be resilient in low oxygen environments but rising temperatures may not be handled so well, especially by its offspring.

A new study conducted by PhD candidate Carolyn Wheeler on the eggs of epaulette sharks showed that increasing ocean temperatures significantly affect the development of its young. The researchers analyzed the growth of epaulette shark embryos until they hatched, – at temperatures of 27°C, 29°C, and 31°C – measuring the growth, development and metabolic performance of the animals. It was found that the growth rates of the embryos increased at the higher temperatures, as in the warmer water the sharks tended to consume their yolk-sacks faster which is their only source of food before they hatch. This in turn caused them to hatch sooner, and due to the reduced time in the embryonic stage they were born smaller and lacking in energy. The newborns which hatched at higher temperatures struggled to survive and needed to feed significantly sooner after birth compared to those at 27°C. Other studies have additionally observed that at 32°C the likelihood of epaulette shark eggs hatching becomes very low.

Epaulette Shark Embryo: Source: flickr.com/CLF

The average temperature of the Great Barrier Reef is currently at 28°C during the period of embryo development in the wild, but with climate models predicting that average temperatures in this region will rise to 32°C by the middle or end of the century these animals are in trouble. As we explored earlier, epaulette sharks are known to be tolerant to low oxygen environments and are more so than any other shark. Additionally, in other experiments it has been found that their eggs and newborns are even tolerant to ocean acidification.

Since the increasing temperatures will likely have a detrimental impact on the epaulette shark – which is considered a tough and resilient species – we can only imagine the negative impacts it will have on other more vulnerable wildlife.

– Adam Soliman

Methane Reduction and the Magic of Mushrooms

When you think of Reishi mushrooms, what do you think of? A delicious food? A health fad? Well it may surprise you to know that beyond everyday consumption, Reishi mushrooms have a high potential for impacting our atmospheric conditions. A recent study done by researchers at the University of Minnesota examines certain fungus’ ability to capture and filter methane, and its impact on the current climate crisis.

 

Reishi Mushrooms. Source: Pixabay

 

Why is methane a problem?

Methane, a greenhouse gas, is one of many chemicals that contributes to the rise of global temperatures. It has many sources, both biological and man-made, the most common being agricultural practices, wetlands, and transportation of coal and natural gas. While most research is being done to reduce carbon dioxide emissions, it is just as important to address methane emissions, as in the first two decades of release, methane can be up to 84% more potent than carbon dioxide. Methane is incredibly effective at absorbing heat, which is what makes the chemical so detrimental to atmospheric conditions.

 

How do Reishi mushrooms help?

While there are currently other organisms that can break down methane, removing it from the atmosphere, there is one critical way that Reishi stands out:

In order for Reishi to degrade methane, the gas does not need to travel through any kind of biofilm, which decreases the total time needed for degradation. 

The cells that make up fungal structures, called hyphae, are able to extend and grow deep within the soil and other environments. When nutrients are detected, they travel through the hyphae until the desired location with the fungus is reached. There is a specific special protein, called hydrophobins, which is found on the exterior of the hyphae, which is responsible for trapping gases such as methane. Once trapped, the gas is transported within the fungus and is degraded as needed.

Mushroom hyphae. Source: Wiki Commons

The researchers who conducted the study found that Reishi mushrooms that are grown outside of the soil have a better removal rate, compared to those in the soil, where natural microbes may out-compete the mushrooms for nutrients. Shockingly, the researchers found that even dead fungi had some function at removing methane from the surrounding air.

While there is still a need for more research to be completed, it can be comforting to know that there are solutions to global warming that can come from the most unlikely places.

– Madeline Filewych

Itching Towards a Solution to Eczema’s Problem

For those who are living with atopic dermatitis, commonly known as eczema, it’s not always fun.

Imagine that one minute you’re going on about your day, then suddenly your skin flares into an itchy, dry and blistering rash. The skin irritation becomes agonizing as soon as you start to feel your skin throb and burn, almost as if a million fire ants endlessly crawl all over your skin.

According to the Canadian Dermatology Association, this is what 17 percent of Canadians deal with throughout their lives. 

Source: flickr.com

Recent Research

A recent study published in the Journal of Investigative Dermatology examined the relationship between an enzyme known as Granzyme B and the symptoms associated with eczema. According to Dr. David Granville, UBC’s Faculty of Medicine professor and researcher, increased Granzyme B secretion causes the enzymes to “eat away” cell-adhesion proteins that function in holding skin cells together. As a result, the skin barrier is weakened which increases skin sensitivity, thereby introducing symptoms like skin inflammation, dryness and itchiness. 

So what would happen if these enzyme levels were decreased?

Granville and his team discovered that by lowering Granzyme B secretion levels with inhibitors, skin cell layers were more likely to remain intact as fewer cell-adhesion proteins were eaten by these enzymes. Symptoms such as inflammation and lesion growth were shown to be greatly reduced compared to such increasing symptoms associated with high Granzyme B secretion levels. As these observed symptoms contribute to dryness and itchiness, these findings ultimately introduces a newer approach towards treating eczema.

A Step Closer to Newer Treatments

How can these findings be implemented into future treatments for individuals who have eczema?

Former UBC postdoctoral fellow and lead author of the study Dr. Chris Turner, suggests that with further research and clinical trials, these findings can potentially introduce topical creams or lotions that can inhibit Granzyme B levels in the future, ultimately reducing symptoms of itchiness and inflammation on affected skin. This potentially brings in treatments that avoid damaging the skin.

“Corticosteroid creams are a common treatment for individuals with AD who experience more severe itching and rashes. However, these can thin the skin when used over a prolonged period of time, which can make skin more prone to damage and infection.” (VCH Research Institute)

Source: med.ubc.ca

As further research opens up more information about eczema and the enzyme that aggravates its symptoms, hopefully it’ll help researchers get closer towards developing potential treatments. Perhaps one day a Granzyme B-inhibiting cream will become available in the market.

After all, no one likes to have itchy, dry skin.

– Tina Huynh

Catnip Magic was a Protection Against Mosquitoes (old)

Catnip is a plant that can bring about a euphoric state and cause most cats to act unusually as if they are drunk. If you own a cat, you may have used catnip products and witnessed your cat rolling, flipping, and rubbing. Some cats even zone out. The responses to catnip are also observed in other felids such as lions and bobcats.

“For cats, catnip may be a recreational drug but it’s totally harmless. […] After about 10 minutes, the cats come back down to Earth” (Wild At Heart, BBC Earth)

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Credit: Wild At Heart | BBC Earth

Why do cats behave in this way?

Since the first feline response was reported by a British botanist back in 1759, this behaviour remained mysterious for a long time. It was generally thought that the responses were purely driven by the euphoric experience. However, in January 2021, a team of scientists from multiple universities in Japan and The University of Liverpool found that the responses allow cats to protect themselves from mosquito bites.

The team found that in the silver vine plant (which has the same effects as catnip), the significant component that induces the characteristic behaviour is called nepetalactol. The team also found that it has mosquito repellent activity. In catnip, the corresponding chemical is called nepetalactone and has similar properties.

When cats sniff these chemicals, it stimulates the brain system u-opioid. In humans, this system controls the rewarding effects. Researchers confirmed that the stimulation induces cats to rub their bodies and face against the chemical. This rubbing and rolling behaviour transfer the chemical onto their fur, allowing the cat to gain a chemical defence against mosquitoes.

The neurophysiological and functional significance of silver vine response in cats.
Image Credit: Chie Nakayama adapted from Uenoyama, Reiko, et al. doi:10.1126/sciadv.abd9135.

Their findings confirmed that the euphoric experience drove the behaviour. At the same time, it showed that what seemed like a crazy behaviour was surprisingly a functional one. The research sheds light on developing new mosquito repellents for humans in the hope of gaining protection from the transmission of malaria and yellow fever.

– Chie Nakayama