Tag Archives: brain

Not Seeing Gains at the Gym? Have you heard of Mind-Muscle Connection?

When individuals talk about increasing muscle mass and getting stronger, several different strategies are brought up. For example, most people like to focus on nutrition or training harder at the gym. Don’t get me wrong, these are important strategies to improve your physique and build muscle mass, but there is one thing that is often overlooked. This is the phenomenon called “Mind-Muscle Connection”.

A study conducted in 2015 by Joaquin Calatayud and team, describes the mind-muscle connection and what happens when you mentally apply yourself during workouts. If you haven’t heard of mind-muscle connection, you may be wondering what it is and how can this apply to you?

What is Mind-Muscle Connection?

In simple terms, mind-muscle connection (MMC) is when you consciously and deliberately contract a specific or group of muscles in your body. The brain sends a signal to your muscles at the “neuromuscular junction,” telling the particular muscle to contract. The neuromuscular junction acts as a bridge and connects the skeletal system to the human body’s nervous system.

This video showcases what MMC is in a nutshell:

Source: PictureFit (YouTube)

MMC used in Resistance Training

The study determined if performance will improve if an individual focused on specific muscles (chests and triceps) when doing a bench press.The subjects of the study were separated into three groups where they performed the bench press while: 1) not concentrating on any specific muscle in the body, 2) concentrating on the pectoralis (chest) major muscles, and 3) concentrating on flexing the triceps muscles. In these conditions, the subjects performed the bench press at 20%, 40%, 50%, 60% and 80% of their 1-repitition max (1-RM). The final results of the experiment showed that the muscle activity did increase when emphasis was put on the two target muscles, but only up to 60% of their 1-RM.

Man performing bench press. Source: muscleandstrength.com

You may be asking, why is MMC only effective up to 60% 1-RM? This is because when you create a mental connection with your brain to the muscles, it requires concentration and attention. You will only be able to concentrate when you lift a weight that you can manage, for example, around 20-60% of your 1-RM. If you go over 60% of your 1-RM, you will not be able to solely focus on the specific muscle, since your mental focus will be directed towards how heavy the weight is.

How can you create MMC when you lift? Give these two tricks a shot during your workouts:

  • Slow Down: Your muscles have to work more if you move slowly, allowing you to have more time to connect your brain to the specific muscle movement.
  • Ego Check: Many people are obsessed with lifting more and more weight, but instead, focus on the quality of each repetition.

It is common to see muscle growth coming to a halt when going to the gym and when results are not seen, this results in a lack of motivation. For those of you who are experiencing this, MMC can be the missing piece for you.

– Parwaz Gill

Treating Depression: Personalized Deep Brain Stimulation

How would you feel if the treatment or medication you were taking had little to no effect in suppressing your symptoms? Unfortunately, this is the case for 1 in 3 patients diagnosed with depression. These patients fall under a category known as treatment-resistant depression. Personalized deep brain stimulation, a promising alternative to conventional treatments, has the potential to treat various forms of depression by allowing physicians to tailor treatment to an individual.

THE PROBLEM

Depression, which is characterized by low mood, is linked to an imbalance of serotonin, norepinephrine, and dopamine neurotransmitters in the brain. It is a common mental illness that affects the way someone feels, thinks, and acts. However, it is important to note that depression varies significantly among individuals and many other factors play a role.

Source: flickr.com

As stated by Ben Paul from USC Viterbi School of Engineering,

“Mental disorders can manifest differently in each patient’s brain.”

There is no single treatment that can effectively treat the symptoms of depression among all diagnosed individuals. This makes it hard for physicians to provide the best treatment for their patients.

WHAT IS DEEP BRAIN STIMULATION?

Deep brain stimulation (DBS) is a surgical procedure where electrodes are implanted within specific areas of the brain. By electrically stimulating these parts of the brain, physicians can reduce the symptoms associated with depression. The amount of stimulation is controlled by a pacemaker that is placed under the skin on the chest.

The video below explains this procedure further and contains an interview with Edi Guyton, a patient who had this surgery: 

Source: CNN | Youtube

PROMISING ALTERNATIVE: PERSONALIZED DEEP BRAIN STIMULATION 

Even with deep brain stimulation, each patient’s response to treatment will be different. However, one of the pros of deep brain stimulation is that it results in immediate changes. This is the key component that allows physicians to personalize treatment. A 2021 research study led by Dr. Maryam Shanechi and her team at the USC Viterbi School of Engineering explains an approach that can be used to predict and see how an individual’s brain responds to stimulation. Her research will allow physicians to monitor brain regions in real-time.

How is this done? 

       Two tools have been designed: 

  1. Electrical stimulation wave to map brain activity
  2. Machine-learning techniques that can learn the mapped brain activity which is collected during stimulation 

The stimulation wave tool randomly changes the characteristics (amplitude and frequency) of the electrical impulse over time. A change in these characteristics is the equivalent of changing the dosage of a medication. Analysis of brain activity during these changes will help physicians determine the correct stimulation doses. 

THE FUTURE: TREATING DEPRESSION

Dr. Maryam Shanechi’s research will allow physicians to personalize deep brain stimulation for all patients diagnosed with depression. This can help physicians overcome the difficulty of assisting individuals with treatment-resistant depression. Success within this field of personalized deep brain stimulation not only holds great potential for treating depression but can also lead to improved treatments for other psychiatric disorders. 

Source: flickr.com

 

– Samantha Nalliah

Treating Depression: Personalized Deep Brain Stimulation

Source: flickr.com

How would you feel if the treatment or medication you were taking had little to no effect in suppressing your symptoms? Unfortunately, this is the case for 1 in 3 patients diagnosed with depression. These patients fall under a category known as treatment-resistant depression. Personalized deep brain stimulation, a promising alternative to conventional treatments, has the potential to solve this problem by allowing physicians to tailor treatments to an individual’s needs.

The Problem

Depression, which is characterized by low mood, is linked to an imbalance of serotonin, norepinephrine, and dopamine neurotransmitters in the brain. It is a common mental illness that affects the way someone feels, thinks, and acts. However, it is important to note that depression varies significantly among individuals and many other factors play a role. As stated by Ben Paul from USC Viterbi School of Engineering,

“Mental disorders can manifest differently in each patient’s brain.”

There is no one single treatment that is able to effectively treat the symptoms of depression among all diagnosed individuals. This makes it hard for physicians to provide the best treatment for their patients.

What is deep brain stimulation?

Deep brain stimulation (DBS) is a surgical procedure where electrodes are implanted within specific areas of the brain. By electrically stimulating these parts of the brain, physicians can reduce the symptoms associated with depression. The amount of stimulation is controlled by a pacemaker that is placed under skin on the chest.

The video below explains this procedure further and contains an interview with Edi Guyton, a patient who had this surgery: 

Source: CNN | Youtube

Promising Alternative: Personalized Deep Brain Stimulation 

Even with deep brain stimulation, each patient’s response to treatment will be different. However, one of the pros of deep brain stimulation is that it results in immediate changes. This is the key component that allows physicians to personalize treatment.

Research led by Maryam Shanechi and her team at USC Viterbi School of Engineering have figured out a way to predict and see how an individual’s brain responds to stimulation. This allows physicians to monitor brain regions in real time.

How is this done? 

           Two tools have been designed: 

  1. Electrical stimulation wave to map brain activity
  2. Machine-learning techniques that are able to learn the mapped brain activity which is collected during stimulation 

The stimulation wave designed by Maryam and her team randomly changes amplitude and frequency of the electrical impulse over time. A change in amplitude and frequency would be the equivalent to changing the milligram dose of a pill. Analysis of brain activity during these changes will allow physicians to arrive at the correct stimulation doses.  As a result, physicians will be able to personalize and tailor the deep brain stimulation for the individual. 

This treatment can be used to find an effective approach for almost all patients diagnosed with depression.  Success within this field of personalized deep brain stimulation will hopefully lead to more application for other mental disorders. 

– Samantha Nalliah