Category Archives: Biological Sciences

Eating your mucous: a defence mechanism?

 

 

Mucous-ingestion:source flickr commons

Mucous-ingestion by this man, although disgusting,may actually be aiding his immune system. Image by imgarcade. Source: Google Image

 

 

As much as everyone would like to hide it, you have all picked your nose at one point or another in your life. And each time, you’ve probably been reminded of how disgusting and unhygienic the act is. Some people even take this behaviour to the next level, proceeding to ingest the hidden treasures. Could ingesting the contents of your nose actually be the opposite of what your mother has told you? Even, healthy?

Professor Napper at the University of Saskatchewan hypothesizes that eating the pathogen-containing mucous from the nose can actually produce an effect similar to that of a vaccine. The mucous and the hairs in the nose are a part of the innate immune response, which is essentially the first line of defence against invading pathogens. When you ingest the mucous, you’re ingesting all of these pathogens, some of which are potentially very dangerous if they enter into your bloodstream. Once ingested, these pathogens skip the bloodstream and make their way to the gastrointestinal tract where they teach our immune system to defend, such as a vaccine would. Professor Napper’s work is still in the beginning stages and no formal study has been conducted.

S.aureus, common pathogen in nose: source Google commons

S.aureus is a common pathogen in the nose that may be ingested and induce an immune response. Raeky. Source: Wikipedia

On the other hand, Dr Bischinger’s work, which is summarized in this article , describes the mechanism with which the immune system is boosted. He believed that  the pathogens that you introduce from the nose to the body, similar to those of vaccines, are already weakened. He suggested that there are bacteria-killing properties in the mucous of the nose that kill and weaken most of the bacteria, allowing it to be easily contained by our immune system. This mechanism  produces antibodies that our body desperately needs when the full-strength pathogens enter the body.

Moreover, parallels could be drawn from this to that of mothers who kiss their babies in the hopes of boosting their child’s immune system.  In the same way, pathogens that the baby is exposed to are weakened by the mother and then passed on to the baby, producing long-lasting immunity.

Mother kissing the baby: source Google commons

Mother kissing the baby in the hopes that she can provide the baby with weakened pathogens that can be more easily handled by the baby’s weak immune system. Image by Vera Kratochvil. Source Google Image

In conclusion, although pending actual scientific studies, I think that this just might be the natural immunity boost that we all need. However, I don’t think we are ready as a society to start picking away at our noses whenever we please!

 

-Gurtaj Mahil

 

Unmanned Aerial Conservationists…?

Unmanned Aerial Vehicles (UAV) or, more commonly, drones have been used by the United States military for many years. They are associated with warzones and the subsequent collateral murder of innocent civilians. Attempts to kill 41 men by the US have resulted in the deaths of an estimated 1,147 people in Pakistan alone. But what if drones were adapted to conserve rather than kill? NGOs such as SoarOcean and ConservationDrones have been developing drone technology to serve as wildlife protection.

The rainforests of Sumatra and Borneo are home to the orang-utans, a tree dwelling member of the great apes. Their habitat is being converted to palm trees at an ever increasing rate by developers keen to cash-in upon the rising demand for palm oil, a substance that is estimated to feature in half of all packaged products sold in supermarkets. This has led to a fall in orang-utan numbers, from 300,000 to fewer than 50,000. ConservationDrones are working with local NGOs to survey the forest habitat to obtain a better picture of the individuals movements and where they are likely to aggregate in groups. This evidence will provide strong support to pressure the government into protecting certain areas. Previous efforts on foot can be expensive and time-consuming in the dense jungle, whilst a 30-minute flight can capture 900 images of 30-times satellite clarity over a 30 km2 region. A vast improvement upon conservation efforts.

Photo courtesy - National Geographic

Photo courtesy – National Geographic

Drones could also be used to tackle Illegal, Unreported and Unregulated (IUU) fishing, a major concern to Belize due to its detrimental effect upon environmental, social and economical axes. Such practices are often undertaken by distant water fishing vessels from other nations who hide their identity through changing flags in order to obtain the valuable resources from the territorial waters of vulnerable countries without prosecution. The 70 enforcement personnel of Belize struggle to police the 386 km coastline and 200 islands, hence the need for drones. These could catch illegal fishers by surprise to gather evidence for prosecution in court, eventually acting as deterrent from the territorial waters. The $2,400 cost per drone is economically viable but practice must be undertaken and safety protocols established prior to their implementation. Belize could soon be patrolled by the buzz of drones to protect from and prevent IUU fishing.

Blog 1 - Rhino photo

Photo courtesy – Jeremy Smith

The poaching of rhinos across Africa has seen a stark increase in recent years, from 122 deaths in 2009 to 388 in 2012. Their horns are of high value due to their demand for use in traditional Asian medicine. Organised gangs deploy advanced technologies to exploit this illegal market with park rangers out-manned and out-gunned. However, the use of drones could be an alternative combative measure. The Wildlife Conservation UAV Challenge is an international competition whereby robotics teams are tasked with building inexpensive, easy-to-fly drones with an emphasis upon data process for use in wildlife protection. See the following video for more information:

YouTube Preview Image

Video courtesy – National Geographic

For more interesting uses of drones, check out this link!

Toby Buttress

Drying your hands doing more harm than good?

With the growing need to constantly be efficient in almost every aspect of our lives we could be doing more harm than good. Hand washing is considered the most simple and important procedure to prevent sickness but the method we dry our hands may be counterproductive. According to the Malaysian Journal of Pathology, electric hand dryers dispersed bacteria at a radius of 3 feet from the dryer. In the experiment by the department of Microbiology in Kuala Lumpur, Serratia marcescens (bacteria) was placed under the dryer to stimulate someone drying their hands (in a hospital setting) and the results indicated that the bacteria was blown an average of 3 feet. A more recent study done by the University of Leeds also found that electric hand dryers spread bacteria in a bathroom setting. Using paper towels does consume trees but is the trade-off worth the risk?

bacteria

Picture of bacteria obtained from Flickr – credit to Cesar H.

Using an air dryer, it takes longer to dry hands relative to paper towels which means that people may not completely dry their hands. This being said, it may be possible that bacteria could grow on surface skin. Skin flora can then be transmitted from one person to another in a variety of ways such as the casual hand shake or simply by touching objects after hand washing. Someone could wash their hands and then dry them using an electric hand dryer and have bacteria blown onto their hands that will spread with contact. In other words a non-contaminated surface can become contaminated with skin flora even if the contact surface is not immediately under the dryer. Electric dryers may not only spread bacteria, it may provide an environment for growth.

Head Dryer

Picture obtained from Flickr courtesy of Walter J.

The environment that is in the inside structure of an electric hand dryer provides conditions suitable for growth of bacteria according to Dailymail. Bacteria can multiply in the electric dryer in between uses and then spread by becoming airborne when the dryer is turned on. By using electric air dryers to ultimately reduce the amount of trees that are cut down every year according to the Slate. Paper towels do not cause bacteria to become airborne but they do cause many trees every year to be cut down and are inefficient in terms of the environment. Electric air dryers do provide a good alternative to paper towels but they cause the spread of bacteria. As technology and science continue to improve hopefully a solution to this problem will be in the near future where we can protect the environment as well as ourselves at the same time. It may seem like a small part of our lives – washing and drying hands – but the consequences can potentially be severe. In the end, using electric hand dryers saves millions of trees worldwide and is worth the risk in my opinion. Below is an example video of the efficiency of electric hand dryers.

Kevin Nand

Can Lucid Dreaming Provide Insight into Psychosis?

Psychosis is a serious mental disorder, how can we treat it? A is for psychosis. Source: Flickr Common. Credit to: Al Shep

Are the characteristics of dreaming and the characteristics of the psychosis of mental illness similar to some extent? As it turns out, both dreaming and psychosis share many similar cognitive peculiarities, with the most common being a lack of insight into current mental state. With this in mind, neuroscientists are tackling a new approach that could allow psychotic patients to gain insight into their own pathological state. This approach consists of understanding lucid dreaming, a rare phenomenon where the sleeping subject is conscious that he or she is dreaming, thereby gaining insight into their dreaming state. In other words, scientists believe that by understanding how lucid dreamers come to be aware that they are dreaming, they can use this knowledge to teach psychotic patients to gain insight into their illness.

In my opinion, psychosis is one of the most debilitating conditions of all psychiatric disorders as the majority of people suffering from psychosis have no insight into their pathological state. I believe a good way to study this “lack of insight problem” would be to use lucid dreaming as a new therapeutic approach in order to train patients to gain insight into their own mental states. The idea of such a model has already been proposed to study this loss of touch with reality but was wholly speculative, until recently. Indeed, in a recently published paper, researchers examined the activation of neurons in the brains of both lucid dreamers and psychotic patients. Their results showed that the impaired brain regions of the cerebral cortex in psychotic patients who lack insight into their pathological state highly overlap with brain regions activated during lucid dreaming. That being said, if we further study the phenomenon of lucid dreaming, and how lucid dreamers get to be aware of the fact that they are dreaming, we could use this approach as a viable treatment option for those suffering from psychosis and lacking insight into their disorder.

One such treatment approach is metacognitive lucidity training, where subjects are not only trained to develop self-reflective thoughts but also are also trained to develop a conscious understanding of their own mental state. This treatment has been used in a variety of mental disorders, such as phobias and nightmare therapy, where subjects can improve their capability of self-reflecting. By assessing this therapeutic approach to individuals suffering from schizophrenia, or other psychotic disorders, these patients might learn skills that lucid dreamers gave developed in order to gain insight into their state of mind.

One possible limitation with this type of approach, however, is the fact that this phenomenon of lucid dreaming is quite rare. Nonetheless, I still believe that further research on the topic could be a great tool to shed light on the psychotic state present in mental disorders such as schizophrenia.

Schizophrenia. Source: Flickr Creative Commons. Credit to: Dejenee Shiflet.

Psychosis is most often characterized by a loss of touch with reality and a lack of insight. Schizophrenia. Source: Flickr Creative Commons. Credit to: Dejenee Shiflet.

 

If you feel like experiencing a brief simulation of a psychotic episode, watch the video below!

Source: Youtube. Credit to: braschlosan

Sara Larivière

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Life in a Petri Dish: From Skin Cells to Fertility

The number of partners facing infertility in Canada has doubled since the 1980s; it is now predicted that every one in six couples face infertility. With the numbers rising, due to factors such as obesity and substance use, this issue is becoming increasingly more common in our modern world and scientists across the globe are in a constant race to overcome it.

New research emerging from Cambridge University has provided hope in the form of a new infertility treatment. In collaboration with the Weizmann Institute of Israel, researchers have come forward with a potential new form of in-vitro fertilization. Its origin? Human adult skin cells.

IVF: the insertion of sperm into a human oocyte (egg cell).

IVF: The insertion of sperm with a glass pipette into a human oocyte (egg cell). In-vitro Source: Wikimedia Commons

For the first time, scientists have been able create manmade (reproductive) primordial germ cells, known as PGCs; these cells act as predecessors and are considered the common origin of  both sperm and egg cells. PGCs arise from pre-existing adult stem cells, which is an undifferentiated cell that has the ability to develop into many different tissue types. Their ancestor-like quality that creates a common origin, allows the eventual creation of  many different cell types, such as skin and liver cells.

Kyoto University used skin cells to create mice pups in 2012.  Lab Mouse Source: Google

Kyoto University used skin cells to create mice pups in 2012.
Lab Mouse Source: Wikimedia Commons

The team of researchers, led by Hanna and Azim Surani, followed a “recipe” originating from a Stem Cell Lab at Kyoto University, who created mice pups from a female germ cell by re-programming stem cells back in 2012. Based on this, the Cambridge-Weizmann team replicated the in-vitro portion of the experiment, where they grew the cells in a sterile and controlled environment.

The team was successful in making the primordial reproductive cells from human stem cells. The key finding was a gene known as SOX17, who is responsible for directing stem cells into their specialization; this is how primordial germ cells are created. This gene can also direct stem cells into becoming the external layer of skin, therefore showing that the reprogramming of an adult tissue type, such as skin cells, could give rise to the primordial germ cells.

Current British law has banned any fertility clinics in the United Kingdom from using a manmade sperm and eggs to treat an infertile couple, due to both ethical reasons as well as safety concerns. If this law is changed, the creation of a genetically identical sperm or egg cell can be taken from a patient for use in in-vitro fertilization.

Mother and Child Source: Wikimedia Commons

Mother and Child
Mother Source: Wikimedia Commons

This discovery has laid down foundation for all future research; scientists can now compare the development of both sperm and egg cells in both healthy as well as infertile people. Representing a huge step forward in the world of stem cell biology, the researcher’s work, published in the journal Cell, may mean a change in the age at which a woman can stop having children. This breakthrough means that manmade primordial germ cells are capable of passing on an offspring’s genetic code to their own offspring, creating the fundamental bond from generation to generation.

Check out Cambridge University’s video on a similar topic, the derivation of brain cells from skin cells:

Thanks for reading!

Samantha Mee