Tag Archives: ethanol

Is alcohol beneficial?

 

Alcohol Beverages (Source: http://sports.yahoo.com/top/news?slug=ycn-10798319)

In terms of chemistry, an alcohol is an organic compound that contains the hydroxyl functional group (-OH) attached to a hydrocarbon group. The hydrocarbon group has a central carbon single-bonded to three other hydrogen atoms. Thus, the general formula for alcohols is CnH2n+1OH. However, in everyday use, the word “alcohol” refers particularly to ethanol, of which the chemical formula is C2H5OH, and it is the type of alcohol used in alcoholic beverages. For thousands years, humans have been producing and consuming ethanol as alcoholic beverages. Because of its intoxicating effects, ethanol has been an intoxicating ingredient of alcoholic beverages since ancient times. This feature makes the alcohol be consumed widespread, for it relieves people’s stress. There has been a controversy whether the alcohol is beneficial to our health or not because it can cause a fatal illness to humans at a sub lethal dose.

However, to accurately examine the effects of alcohol to our health, we need to look at how cell biology mechanism of it works. The primary metabolite of ethanol is acetaldehyde and secondary metabolite is acetic acid, which largely cause the toxicity of ethanol. Toxicities of acetaldehyde and acetic acid are similar to those of aldehydes and carboxylic acids, which are the products from the breakdown of primary alcohols. Within the human body, alcohol dehydrogenase converts ethanol into acetaldehyde, and then acetaldehyde dehydrogenase converts it into the acetyl in acetyl CoA, which is the final product of fat and carbohydrate metabolism. Ethanol may be considered as a nutrient since acetyl can be used to produce energy for these metabolisms. Nevertheless, acetaldehyde contains higher level of toxicity than ethanol, and it has been revealed that acetaldehyde is closely related to most of the clinical effects of alcohol.

Metabolism of Alcohol (Source: http://pubs.niaaa.nih.gov/publications/AA72/AA72.htm)

From the mechanism above, when used in therapeutic dose, alcohol does not cause serious and harmful problems to humans. Alcohol in light dose decreases the risk of heart disease. The effect of alcohol to people’s health is clearly exhibited by the study done by Liu, PM. In this study, the relationship between alcohol consumption and risk of stroke and coronary heart disease was examined among Eastern Asian men. It was found that light alcohol consumption (≤ 20 g/d) reduces the risk of stroke, while heavy alcohol consumption increases the risk of stroke; and moderate alcohol consumption (21–60 g/d) helps decreasing the risk of coronary heart disease morbidity and mortality.

In conclusion, small to moderate alcohol consumption is beneficial to our health. Based on many studies and experiments, it was shown that people who consume alcohol moderately have fewer heart attacks than those who do not drink at all, and also that moderate drinking lowers risk of diabetes in both men and women. The consumption of alcohol in large dose causes intoxication though. Depending on the dose and the regularity of its consumption, alcohol can be beneficial or harmful to our health.

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This shows how the alcohol has beneficial effects to people’s health by Dr. Matt DeVane. (This video is from the youtube username HeartSmartMD.)

-Jong Jin Park