Tag Archives: cardiovascular

To drink, or not to drink…

Paracelsus

Paracelsus Source: Wikimedia Commons

Society has always incurred the issue of dosage. To quote the famous philosopher, Paracelsus, “All substances are poisons; there is none that is not a poison. The right dose differentiates a poison and a remedy.”

Parcelsus’ words do not falter, especially with regards to alcohol consumption. Particularly in red wine, there is a “substance” called resveratrol, a naturally occurring chemical compound found in the skin of certain grapes and berries considered to be an antioxidant. A blog from cancer research UK indicates that a low dose of resveratrol is considered to be 5 milligrams which is equivalent to a 250 mL glass of wine, or roughly 9 ounces. This minimal dose would be enough resveratrol to have an observable effect on the human body.

But how does resveratrol affect the body? You may have heard about the relation between red wine and the heart. In fact, the video below by Buzz60 introduces a study conducted in Israel by the Ben-Gurion University of the Negev which has shown that red wine has an increased positive effect on cholesterol levels. The study had 1/3 of the subjects drinking a glass of water with their meal, 1/3 drinking white wine and 1/3 drinking red wine. Excuse the cheese of this video, but it does go quite well with these wine facts.

http://www.dailymotion.com/video/x3aobr3

As mentioned, resveratrol is an antioxidant; it donates an electron to the free radicals in the body, thereby abolishing the harmful abundance of radicals. By inhibiting free radicals, resveratrol promotes the production of nitric oxide. Consequently, the presence of this biological messenger – nitric oxide – stimulates arteries to relax, open up and allow blood to consistently flow throughout the body. This constant flow aids in the avoidance of a coronary artery spasm; a condition defined as the temporary yet sudden narrowing of the artery walls.

Essentially, red wine contains resveratrol, resveratrol promotes the production of nitric oxide and nitric oxide allows blood vessels to dilate allowing blood to flow steadily throughout the body. The video below echoes this process.

https://www.youtube.com/watch?v=eVoH67d0IDk

So, to sum it all up, go ahead and get that 9 oz of red with your dinner! Your circulatory system prefers it.

Paria Assadipour

Type II Diabetes? There May be a Cure for That

How many times have we passed up a delicious sugary treat because we know that it’s unhealthy for us? It just so happens that scientists may have discovered everyone’s favourite new enzyme: glycerol 3-phosphate phosphatase (G3PP).

white chocolate cake with raspberry cream filling and white chocolate buttercream

– Image Source: Sharyn Morrow, Flickr

A recent study by scientists at the University of Montreal Hospital Research Centre discovered that the mammalian enzyme, G3PP, played a crucial role in controlling sugar accumulation in the body and certain fat conversion processes. They observed that G3PP was expressed at various levels in different tissues and that in the presence of this enzyme, there was lower body weight gain and higher levels of high-density lipoprotein which may protect against heart attacks and strokes.

The new discovery of the G3PP enzyme could also lead to promising therapeutic treatments of obesity and type II diabetes. Type II diabetes is a disease in which specific cells of the pancreas have been presented with excess glucose, and over time, insulin secreted from these cells loses its function on other cells throughout the body or they do not react to insulin properly. This results in high blood glucose levels that can affect other organs of the body and lead to serious complications such as kidney failure. Since the G3PP enzyme prevents excess production of glucose and is able to detoxify excess sugar from cells, it could play a major role in treating type II diabetes.

credit: Animated Diabetes Patient

According to the Government of Canada, there are approximately 60,000 new cases of type II diabetes yearly. Factors that minimize your risk of type II diabetes include limiting fat and sugar intake, as well as keeping cholesterol and blood fats within a target level.

It’s still too early to say whether or not G3PP will be an effective treatment for the reduction of type II diabetes, cardiovascular disease, and obesity. Although researchers are optimistic that the G3PP enzyme will reduce the risk of people acquiring type II diabetes, more experimentation with the G3PP enzyme will need to be done before we can determine whether it will be an effective treatment in the future.

– Brian Infanti