Category Archives: Science in the News

End of the road for Gingers?

Should red heads around the world be in panic as reports of the extinction of their unique gene runs through the media? Should all gingers rush to mate with another ginger in fear of this theory?

The red hair gene first appeared thousands of years ago in northern Europe as a result of a genetic mutation in the MC1R gene. It was first reported that having the red headed gene increased the ability of the body to cope with sunlight as it allowed for more vitamin D in the body. However, carriers of the gene today are more sensitive to heat and cold, as well as, more likely to acquire skin cancer.

It is rare to spot red haired individuals; in fact, National Geographic reported that less than 2 percent of the world’s population today carries the gene for red hair. Genetic scientists are reporting that the “dying breed” will be basically extinct in the next 100 years. However, there seem to be experts that argue that the gene can merely be dormant for several generations before appearing once again.

Genetics at Work Image Gallery

The reason for the prediction of extinction is due the recessive nature of the gene. Both parents must pass on the recessive gene for the offspring to physically express red hair. However, we should all be aware that a couple does not have to both be red headed in order for their children to be the same. Two blondes, or brunettes also have the possibility of producing an offspring with that phenotype, as long as they are both heterozygous dominant for the gene.

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Therefore, while there is a chance for a decline of red headed populations due to lower chances of a red headed individual pairing with another red headed partner, the potential of having red hair will not go away. For now, it is too early to determine that extinction of all redheads will occur.

-Maral Altanbadralt

Possible Clinical Benefits of Yoga

There are many myths among the general public regarding yoga. For example, some believe that yoga is only for those who are super flexible, or perhaps, only for women. I’m writing this to convince you that these myths are very false, and as it turns out yoga may hold some other lesser known benefits for its practitioners.

Yoga Pose By Lululemon Athletica via Wikimedia Commons

Yoga is a good way to improve on flexibility, it can help you with breathing as well as core strength. However, did you know that it may be able to help you lift you mood or help you sleep? A review of 16 recent studies found that yoga could help those who suffer from depression as well as those who complain of sleep problems. The studies suggested that yoga was able to influence chemical messengers in the brain, inflammation in the body, and other biological processes that influence us.

The way yoga influences our mood is by the effect it has on GABA. Low GABA levels in the body are associated with depression and other anxiety disorders. A study was performed on a group of people who regularly attended yoga classes and compared these people who went on walks instead. The study found that people who were doing yoga had higher GABA levels than those who walked, even though the two groups were burning similar amounts of calories. Also, it was found that these same people also reported a better overall mood and general well being compared to the walkers.

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Health Benefits of Yoga by CTV Edmonton

When hormones in the body are out of sync, many processes we take for granted can get thrown out of whack. For example, Cortisol (AKA “the stress hormone”) can have many negative effects on our body. It has been known to increase blood pressure, decrease immune function, impair cognitive function, increase abdominal fat, as well as a laundry list of other symptoms. Many of these problems can be treated by prescription pharmaceuticals. However, there is also one other widely recommended treatment for all of these problems……you guessed it, yoga!

For those of you out there looking for a new form of exercise that isn’t as high impact as running, or simply just looking to lead a healthier lifestyle, yoga could be the thing for you. It is not just the slow exercise solely for holistic women that everyone seems to think it is. It has become more popular in recent years because of its health benefits becoming known by the general public. I have recently taken to doing yoga a few times a week, and i can vouch for its efficacy. It’s a great way to get into a more healthy lifestyle for all of you out there who are falling behind on those new years resolutions.

– Alex Gibson

Hairy Eyeball?!

I think we can all agree that one of the most annoying occurrences that can happen in our day to day lives is when we get a hair in our eyes.  That annoying feeling, the constant blinking and the frantic rubbing to try and retrieve what feels to be the thickest hair you’ve ever made out of one of the most sensitive parts of our body.  Now, imagine how this unnamed 19-year old man from Iran felt when doctors found out he had hairs growing out of his eyeballs.

A Limbal Dermoid. Author: A Akram, via Flickr Creative Commons

Now, this isn’t something sudden that just appeared in this young mans eye, but is actually something that had been with him since he was born and gradually increased in size as he got older.  While not causing any physical pain, it had caused the young man to have vision defects as the effected eye saw 20/60  while the left eye saw 20/20.  It also caused him mild discomfort when blinking and what is reported as, “an intermittent sensation of the presence of a foreign body.”  From the above symptoms and conducting their own tests, doctors were able to identify the mass as a limbal dermoid, a very rare tumour mass found in about one in 10,000 patients made of special choristomatous tissue .

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Video from Youtube by user: 1OneMinuteNews.

Choristomatous tissue is made from the tissue of other body parts.  For example: the tissue in fat, sweat glands, muscles, teeth, cartilage, bone, and skin can all make up choristomatous tissue.  This explains how the young man has hairs growing out of his limbal dermoid, as the tissues in his tumour could be made of skin cells and also other cellular elements that skin cells are made along with such as hair follicles and sweat glands.

This mass can usually be found in 3 different places of the eye, all around the cornea.  It is either found just outside the cornea, slightly overlapping the cornea or in extreme cases , replacing the cornea itself!   The dermoid can vary in colour depending on the specific tissue found in the tumor mass but it is always firm and “fleshy” in nature and would help explain the discomfort the young man felt every time he closed his eye as well as the sensation of the presence of a foreign body.

Luckily, the 19 year-old man  didn’t have the horrific case of having his entire cornea replaced as the tumour was found bordering his cornea (see picture above).  This story also ends with a happily as doctors were able to successfully remove the 5mm by 6mm mass.  While doctors don’t expect improvement in his vision due to this removal, I know for sure he’ll be very happy not having hairs in his eye all the time.

– Ho-Hin Leung

Living with Only Half a Brain?

It is actually possible! There are many cases around the world where people are living with only half a brain. This ability for people to live with only half a brain is due to a brain phenomenon known as plasticity.  Plasticity is the capability of the brain to be modeled by experience. Experiences that we gain throughout our lifetime changes our brain, like modelling clay.

Brain development begins before birth and continues rapidly after. Connections in the brain are created through synapses which allow electrical signals to be transmitted from one area of the brain to another. These synapses are the changes that are responsible for the brain’s plasticity.

Brain development happens through synapses, which are responsible for creating connections. Image obtained via wikimedia commons author US Government.

There are two types of processes that model the brain: experience-expectant plasticity and experience-dependent plasticity.

Experience-expectant plasticity are experiences that every healthy individual expects to gain in their lifetime. For example, vision. With this type of plasticity comes a sensitive time period. If this experience is not met within this limited time period, the window closes and the skill can no longer be developed.

The other type of plasticity is called experience-dependent plasticity. These are neural connections that are created through experience, which can occur throughout the lifetime. These experiences include riding a bike and learning a musical instrument.

The brain’s plasticity can be seen in Michelle Mack, who was born with only the right side of her brain. To compensate for the missing side, the right side of her brain was rewired to take over the functions of the left.

Human brain’s division into the right and left hemispheres. Image obtained via wikimedia commons author Gvdmoort.

Due to the sensitive time period, a child’s brain has a better chance than an adult’s brain to reorganize itself and recover from a brain injury or surgery. 

This sensitive period plasticity is demonstrated in a girl in North Carolina named Cameron Mott. At age 3, she was experiencing 10-15 seizures a day due to an inflammation of the right side of her brain. She underwent surgery to remove the inflamed side of her brain which paralyzed the left side of her body. Immediately after the surgery, she was put into intensive therapy to recover the left side. Due to the brain’s plasticity and her young age, the left side of her brain was able to take over the functions of the right side.

A segment called Today’s Health on the Today Show interviewed Cameron Mott and her family about Cameron’s extraordinary condition:

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The Today Show’s segment, YouTube video from username ichoosepeople.  

Scientists used to believe that the brain was hard-wired and could not undergo changes once the brain was developed. There was the belief that children with only one side of their brain would not be able to live but these real cases have shown the brain’s capability to change known as plasticity.

– Christine Wong

Sci-Fi turned into reality: Transplant organ made from plastic!

A lot of things around us are made of plastic, but did you know that plastic commonly found in soda bottles can be made into a fully functional organ that can be transplanted into patients?

Human organ is one of the most scarce medical resources.  For example, in Canada last year, nearly 5000 Canadians were on waiting list for organ transplant, and about 200 people died while waiting for one. What if YOU needed a transplant organ one day? Wouldn’t it be nice if there were a way to synthesize human organs from scratch? It turns out that stem cell research is the most promising solution to organ shortage.

So what are stem cells? Stem cells are cells that have the ability to self-renew and turn into specialized cells. Examples of stem cells include bone marrow cells and blood cells.

A couple of years ago, a patient named Andemariam Beyene had a tumor in his windpipe and was out of treatment options. His doctor Paolo Macchiarini came up with a radical idea: to build a new windpipe out of plastic and the patient’s own stem cells.

Video about Mr. Beyene’s plastic trachea: 

http://youtu.be/_GyQWAiDu0w

(From youtube user NTDTV)

The tissue engineers first obtained CT scans of the patient’s existing trachea and tailor-made the plastic trachea to ensure it matched precisely.  They then covered the plastic with the patient’s bone marrow stem cells and placed it in a in an incubator.

After two days, the semi-artificial organ was implanted into the patient’s body. The surgery was a success and Mr. Beyene is now breathing normally. In fact, he does not even need to take drugs to prevent organ rejection issues (which are common problems associated with donor organs) because his own cells were used to develop the transplant organ.  

As of today, only simple organs like windpipe have been made from stem cell and transplanted, but the future of stem cell research is promising. It’s possible that in 10 years or so, complex organs built from stem cell will save your life!

-Stella Meng

Why I Wouldn’t Follow Dr. Oz Down the Yellow Brick Road

Dr. Mehmet Oz was educated at Ivy League universities, has won numerous medical awards, is a professor and vice-chair of surgery at Columbia University College of Physicians and Surgeons and came to prominence giving medical advice on the television show Oprah. Sounds highly credible right? On paper yes, but let’s take a closer look.

Photo of Dr.Oz at the Time 100 Gala. Author: David Shankbone, via Wikimedia Commons

First, let’s talk about those “miracle supplements” Dr. Oz so commonly refers to; in particular, Garcinia cambogiaDr. Oz stated that this was “the newest, fastest fat-buster.

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From YouTube user: garciniacambogia009

No exercise, no diet, no effort? It sounds too good to be true, right?  It is.

Slate.com was first to bust this “find” and stated that in 1998 a study looked at its effects as an “antiobesity agent” in 135 people and found that Garcinia cambogia pills were no better than placebo for weight loss. More recently, a study involving 706 participants was unable to provide support that Garcinia cambogia extract had any impact on weight. In some studies, a few trials showed short-term slimming, but the overall effects were so small and most studies were so flawed that the authors were unable to conclude any results. Dr. Oz handpicked data to support his claims because really, who wants to watch a television show exclaiming “Garcinia cambogia: Proven to do nothing!” It seems Dr. Oz has sold his scientific morals for ratings.

Experiencing large disapproval from the scientific community, Dr. Oz decided to conduct his very own experiment to prove he still has his roots firmly planted in the scientific method. Unfortunately, Dr. Oz only managed to add supporting evidence that he does not follow good scientific practices. Looking for toxic levels of arsenic, he tested apple juice from five popular juice makers in the U.S. claiming that he found toxic levels in all five. There are too many problems with this study. First, Dr. Oz asked a lab to test for total arsenic, but there are two forms of arsenic: Organic and inorganic. Organic is found everywhere and is practically harmless. He received a warning letter from the FDA stating that arsenic occurs naturally in many foods and that only inorganic forms are toxic. Testing for total arsenic can therefore not be used to determine whether a food is unsafe. Second, never replicated his own results. He didn’t even question the numbers he got from the lab, which the FDA warned were giving erroneously high results. Yet, Dr. Oz  showed no hesitance when reporting the results on his show. He didn’t express even the slightest uncertainty about his findings. Even the media caught on. ABC’s medical editor interviewed Dr. Oz who danced around the accusations.

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From YouTube user: ABCNews 

These are just a couple instances of Dr. Oz demonstrating a lack of adherence to scientific principles. He may have the brains and the heart for science, but Dr. Oz needs to find his courage as he presents himself as the cowardly lion far too often.

-Nicole Gehring

Ahchoo: Oh no not the flu!

Flu season is gearing up here in Canada so I figured it to be a good time to talk about the flu. Three years ago, there was an unusual flu outbreak with a nasty variant that seemed like it could turn into a pandemic. This year is also a non-typical flu season, as most seasons are. The rate of influenza infection has been on the rise early this year. This means either one of two things: it could mean we are having a flu season that will normalize once it is all over but shifted early or it could mean that we are having a very bad flu season, during which we will see a high peak rate of infection and what we are seeing now is just the beginning.

Flu Trends in BC. Canada: Influenza-like illness (ILI) data provided publicly by the Public Health Agency of Canada.

Doctors recommend that everyone that is 6 months of age or older get the flu shot. If you already got a flu shot this year,  your immune system has been signaled to prepare itself for the invasion of three different strains of flu. A mild reaction such as soreness, headaches and fevers are common side effects of the flu vaccine. There is no downside to getting the flu vaccine other than a few mild side effects, in fact, if more people got the flu vaccine there would be less people getting sick and dying from the influenza virus.

So the question is, “Do I really need to get the flu shot every year?” and to be honest it really depends who you are and who you are around. If you’ve just had a baby, hang out with your grandparents a lot or hang out with someone who is immune-comprised, you’d better get the shot otherwise you risk giving the virus to those who already have a weaker immune system. If you’re a student then getting the vaccine might not be so dramatic although dorms, gyms and schools are warm and moist and what virus isn’t going to love that combination, its basically a giant petri dish. If one person gets sick, everyone gets sick. So it really comes down to can you afford to be sick.

There is no benefit to getting sick with the influenza virus. In fact, there is no reason to even get the influenza virus. We have a vaccine. Yes, there is always the risk that the vaccine may not contain the correct strains and you might get sick anyways but might as well stack the deck in your favor to keep yourself from getting sick.

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A Little bit of Science That’s the Bee’s Knees

The human knee is a delicate structure, and those who have played sports or done any activities that are high impact know it better than anyone. They’ve felt the pain during the activity, felt sore for weeks after, and have thought to themselves whether or not the activity was sustainable – whether it would be possible to enjoy it into their old age, or whether instead it would render them immobile for their later years. There is hope though, as a new surgical technique in the works has shown to significantly help with cartilage regeneration.

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A model of a knee joint. Holly Anissa via Flickr.

The knee is one the most complex joints in the body, and is the meeting place of the femur, the tibia, and the fibula, and is composed of bone, muscle, ligament, tendon, and cartilage. It contains four ligaments (LCL, PCL, ACL, MCL), responsible for the stabilization of the knee joint, a number of tendons, and two large pieces of cartilage that are responsible for absorbing shock and bearing weight.

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I wonder if he’ll be able to do that again in twenty years?

Courtesy of Teebzguy via Youtube

The prognosis isn’t the best for athletes (both amateur and professional) that participate in a number of popular sports, the highest incidence of knee injury resulting from participation in Football, Skiing, Basketball, Rugby, and Soccer. Although very common injuries include the tearing of the Anterior Cruciate Ligament (ACL) and the Medial Collaterial ligament (MCL), cartilage damage is still a very large concern for both athletes as well as the medical community taking care of such injuries. Due to the strenuous forces associated with these high impact sports, over time, the two large pieces of cartilage in the knee wear down. For some athletes, if left untreated, these pieces of cartilage can wear down completely, until all that is left is bone. When this occurs, simple movements of the knee will result in excruciating pain, as the femur, tibia, and fibula all grind together.

There is good news though! A game changing technique coming out of Johns Hopkins University has proven to lead to significantly higher cartilage regeneration than previously used techniques. Current cartilage repair is undergone by drilling tiny micro holes into surrounding bone, in an attempt to allow the stem cells inside the bones to seep out and form into new cartilage. A study, headed by Blanka Sharma, shows that this old technique led to an average of 64% of the tissue being replaced. The new technique, however, employs the use of a hydrogel along with the drilling, and has shown to lead to an average of 86% of tissue regeneration. Jennifer Elisseeff, Ph.D, along with a number of her co-workers speculated that the old technique was ineffective because it lacked structure for the stem cells to grow on. After years of laboratory testing, the first trial proved a success, MRIs showing there to be no mal-effects associated with the hydrogel implants as well as the increased tissue regeneration.

The technique is still waiting for European approval, and for the time being has been taken over by an independent American company, Biomet. Jennifer Elisseeff, Ph.D has high hopes for the technique, stating that she hopes that “it will become a routine part of care and improve healing”.