Biofuels. Good or Bad?

As an answer to the increasing oil prices, energy conservation and concerns regarding global warming, biofuels have been considered a plausible alternative to other energy sources.  Biofuels consist of a variety of fuels, which have been derived from biomass, earth’s renewable biological resources.   Through some reading online, I believe that biofuel is as an environmentally harmful resource for three main reasons.  Whether it be because the fact that food prices will increase with a decrease in crops…or because there will be an actual increase in global warming…or because of the inability for crops to keep up with the demand of biofuel-materials…I feel that biofuels need to reconsidered as an alternative for our everyday energy uses.

Biofuels work at Argonne by Argonne National Laboratory via Flickr Creative Commons

First, biofuel is produced from plant oils and from edible crops, which means that we have to make the choice between food and oil.  Scientists studying this issue have realized that food prices have and will continue to increase with an increasing demand for biofuel.  The increase in demand for a production of biofuels, in particular biofuels from maize and sugarcane, has had a numerous implications on grain supply-and-demand systems around the world.  And because of the need for specifically maize (corn crops), which is extremely profitable to grow, an increasing amount of farmers who previously grew wheat and rice are now switching over to maize crops thus decreasing the availability of wheat and rice.

corn by tricky via Flickr Creative Commons

Second, in order to produce biofuel, the clearing of natural ecosystems for these crops will actually increase global warming contrary to common belief.  This is due to the fact that carbon dioxide is produced when you clear natural grasslands and other land areas to create farmland for biofuels.  The conversion of native habitats to cropland for biofuels releases carbon dioxide into the atmosphere as this is due to burning or microbial decomposition of organic carbon that is stored in the biomass of the earth.  Basically, until the carbon debt is repaid, biofuels from converted lands will actually have greater green house gas emission than the fossil fuels they are displacing.

Clear cutting land for cultivation by Lon&Queta via Flickr Creative Commons

Last but not least, the current crops we are producing cannot keep up with the demand of bio-materials needed for producing biofuel.  Farmers struggle to keep up with the demand for biofuel crops, as this demand shifts up demand for staple crops.  In other words, the biofuel demand is so high, that farmers cannot maintain their main crops, staple crops, and as a result these main crops also end up being in high demand.

It seems as though biofuel will only increase food prices, increase global warming and cause farmers to be faced with an inability for their crops to keep up with the demand of biofuel-materials.  With these main points in mind, I ask you to reconsider the use of biofuels in our society and question whether they are not only beneficial to us humans, but also beneficial to the earth we live and rely on.

-Derek Rejto

The man whose brain has been penetrated by iron bar

We all know that brain is one of the most important human organs. Now imagine someone whose brain has been penetrated by a 1.1 m long iron bar weighting 6 kg …OUCH!! That sounds horrible!

This unfortunate man is named Phineas Gage. Gage used to be a normal railroad worker, but one day at work in 1848 he made a mistake with his explosives which shot an iron bar towards his head. The iron bar entered  his left cheek and pierced through his brain and exited through his skull. With an injury this gruesome and severe you probably think that there is no way he’d survive. That was what people around him thought too: they prepared a coffin for Gage. But amazingly, he survived this terrible accident. In fact, most of his intellectual functions were quite normal because most of his brain was actually undamaged. The primary site of injury was his prefrontal cortex, which resulted in drastic personality change in Gage.

Phineas Gage skull via Wikipedia Commons from uploader Roy Baty

 

 

 

 

 

 

 

 

 

 

Prefrontal cortex is in the anterior part of the brain. Different parts of the brain have different functions and this particular portion of the brain is important for planning, attention, and behaving appropriately in society. Because of damage to the prefrontal cortex, Gage changed to a different person. Before the injury Gage was hardworking, responsible, and popular among his co-workers.  After the injury, however, he was stubborn, impatient, violent, and non-compliant. He lacked self-control and even molested children!Because of his obnoxious personality after the injury, people felt he was “no longer Gage”

Here is a video account of Gage’s story:

from youtube user Jpick311

Gage’s story is a great tragedy but it provided strong evidence that prefrontal cortex of the brain is involved in personality and contributed a lot to brain research.

-Stella Meng

The Art of Acupuncture

Have you or someone you know experienced a persisting headache that didn’t go away even after taking painkillers? If you were from a Chinese family like mine, perhaps the first remedy would be the suggestion of Acupuncture: the practice of penetrating skin on certain areas of the body with needles to “heal” physical pains and ailments. For over thousands of years, the Chinese have been using this method to treat pains, allergies, paralysis, asthma and many other illnesses.

A sterile needle used in Acupuncture (lengths may vary). No drugs are introduced into the body. Source: Wikimedia Commons

As a victim of these needles, I had wondered, how could pricking one’s body with very fine needles provide relief of ailments? Could science be used to explain this treatment? First, let’s look at the basic concepts of this practice.

Qi and the Meridians

Acupuncture practitioners believe that aches and pains are a result of blockage or irregular flow of Qi (pronounced “chee”): life energy that flows throughout the body of all living things. This “Qi” flows throughout the body via pathways or Meridians, which are known to reach tissues of the skin, muscles, bones, joints and organs. Unlike the conventional needles used for giving shots, acupuncture needles are very thin and do not puncture or damage tissues. Inserting these needles in certain areas (known as pressure points) of the meridians unblock or assist the proper flow of Qi, ultimately relieving the individual of ailments.

 Outline of the different meridians in the body.
Source: Wikimedia Commons

Seems pretty far-fetched right? The idea of fixing the flow of “magical life energy” inside one’s body isn’t exactly convincing to scientists and especially those who hate needles. However, a large abundance of testimonials, reviews and research articles have repeatedly claimed the effectiveness of acupuncture and this in fact, has garnered the interest of many western doctors and researchers.

A Scientific Approach

In an attempt to provide a scientific explanation for the effects of acupuncture, researchers have studied the impact of needle insertions on the brain using fMRI. It was found that triggering certain pressure points decreased the activity in structures of the brain involved with pain sensation, with no negative effects on other areas of the brain.

In addition, several studies have also discovered the correspondence between pressure points and nerve bundles or muscles within the body. For example, an individual having a heart attack will experience pain running from their chest to the length of their left arm. Coincidentally, this pathway is associated with what acupuncture practitioners know as the “heart meridian”. One study finds the stimulation of this area to affect heart rate and areas of the brain associated with cardiac muscle regulation.

Although many doubts still remain about the evidence behind acupuncture treatments, interest in this practice has become increasingly popular, with more and more evidence supporting the effectiveness of these needle insertions.

Check out the video below for more information on Acupuncture

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Video from user: aguinther

   – Grace Lam

 

Will bananas last forever?

Banana via Flickr by Gori

Bananas are one of the most popular fruits in the world. It is cheap, tasty, and nutritious.

They are very rich in nutrition. At only 110 calories per 4-ounce offering, high concentration of vitamin B6, which plays a significant role in fighting infection, is contained. Also, bananas are rich in potassium and fiber. It is known that bananas are the staple diet for half billion people in Asia and Africa.  

While the fruit itself is loved as an important dietary staple, the other parts of plants are used as  food, clothing, paper, and tableware.

A box made with banana paper via a company DwellSmart by Terracycle

A box made with banana paper via a company DwellSmart by Terracycle

However, we will be saying good bye to beloved bananas. It is estimated that they will be extinct in about 10 years.

What are threatening bananas?

We have been consuming almost only one type of banana: Cavendish banana, which makes up 99% of consumed bananas.

They have a critical problem. Cavendish are seedless and cannot reproduce sexually, so all plants of a single variety are grown from cuttings. Basically, they are clones of one another and equally vulnerable to diseases. Because Cavendish are genetically identical,  if one member of population is attacked by bacteria, then the whole population will be killed soon.

There are three types of diseases that are threatening bananas:

  1. Panama disease, caused by a soil fungus, which wiped out the Gros Michel variety in the 1950s
  2. Black sigatoka, another fungal disease which has reached global epidemic proportions 
  3. Pests invading plantations and farms in central America, Africa and Asia alike.

Among the three types of disease, the most threatening type of Black sigatoka. It first appeared 20 years ago in Malaysia.  At first time, it spread slowly, but not it is moving at a rapid speed.

You might be wondering why farmers don’t use pesticide to kill bacteria. It is reported that as soon as a new fungicide is used to kill bacteria, surprisingly,  bacteria develop resistance.  Fungicide is very ineffective against the bacteria, especially against the black sigatoka.

Another type of diseases which endangers bananas is black leaf streak disease, which is caused by fungus Mycosphaerella fijiensis.

M. fijjensis by Cecilia M. Rodriguez-Garcia via Flikr

This fungus kills banana plants by affecting  leaf photosynthesis, and causes premature ripening.

banana leaf affected by bacteria via Flikr, by  Cecilia M. Rodriguez-Garcia

 

“It starts with small flecks and spreads to the whole banana leaves – the disease can totally destroy the whole banana plant,”Stephanie Robert, a molecular virologist said.

Then what do we have to do?

At this moment, only genetic modification (GM) is solution.  With the traditional techniques of selective breeding, ones with ability to resist against disease will be developed and they will be cloned.

 

Impending Doom: A World Without Antibiotics

Imagine a world where the common cold or a cut on your finger could be potentially life threatening. Operations, transplants and even child birth could once again be deadly. This nightmarish situation might not be as far fetched as some might think. The World Health Organization warns us of such a future – one  without antibiotics.

Sir Alexander Fleming‘s discovery of antibiotics was one of the single greatest contributions to medicine. He’d made the discovery of penicillin in 1945, but even then the awareness of bacterial resistance to the drug was present. Sir Alexander Fleming stated:

It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body.

Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.”

Sir Alexander Fleming.
Source: Wikimedia Commons via Calibuon

The resistance that Sir Alexander Fleming mentioned is materializing into a harsh reality of today. As bacteria become exposed to different drugs, they eventually adapt and find ways to survive, rendering the drug ineffective. The US Centers of Disease Control point out the emergence of “nightmare bacteria,” those that are capable of resisting multiple drugs, as well as a select few that are immune to all antibiotics. For the most part, as long as new and improved drugs are developed, resistance to the majority of bacteria will not be a problem. However, there has not been a discovery of a new class of antibiotics since 1980.

Scanning electron micrograph of Staphylococcus aureus bacteria (gold) outside a white blood cell (blue).
Source: Wikimedia commons via NIAID/NIH

Although antibiotics are the main cause of the adaptation and development of more resistant strains of bacteria, a world without antibiotics would be far more dangerous. Antibiotics are extremely important in compensating for a suppressed immune system resulting from major surgeries or long term treatments such as chemotherapy. A future without antibiotics is surely a grim one.

Some initiatives have already been taken in order to decrease the amount of unnecessary use of antibiotics. Europe, for example, has banned the use of antibiotics to increase the growth of livestock, as it can promote resistance in bacteria. It has also been argued that antibiotics should be far more expensive, forcing people to reassess how badly they need them.

Professor Laura Piddock, from the Institute of Microbiology and Infection at the University of Birmingham, talks about the importance of using antibiotics carefully:

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Source: YouTube via pharmamixvideo

The speculation of a future without antibiotics forces us to rethink our casual use of the drug. Although the description of such a situation may seem a little over exaggerated, the message should be taken seriously or dire consequences may ensue. While bacterial resistance to antibiotics is increasing, careful regulation of its use could prevent this “bacterial apocalypse” that is so vividly described.

 

– Curtis Ma

 

What do you know about “humanized mice”?

Ordinarily, doctors wouldn’t have much choice for a 56-year-old patient with advanced colon cancer which is one of the deadliest diagnoses, but to try chemotherapy drugs  one after the other each coming with their own massive side effects or to strike the tumour with a bunch of different chemicals that appeared to be functional in previous cases. But today, doctors have a new brilliant option! And that is to try out potential treatments on mice. Scientists were able to  plant human tumours in mice before; yet, there was no guarantee as to how the mice would metabolically react with the implant. That is, if the mice’s reactions would be in anyway similar to that of humans.

Mouse being injected with chemotherapy drugs, credit: Aaron, from aaronlogan.com/blog

In a new approach by Alice Chen, the Lemelsen-MIT prize winner at the University of Stanford in the U.S, young mice are engineered to lack immune systems and then receive portions of human immune system as transplants. As the mice grow older, they tend to develop a very human-like immune response system which, as a result, reacts to drugs and infectious agents just as human immune system would.

Dale Greiner of the University of Massachusetts Medical School said: “the idea is that you can take human immune systems and put them in a mouse and make them functional, and by doing so you can manipulate them as if you were manipulating little humans without ever putting patients at risk.

Here is a video of Alice Chen explaining how she first invented this method by transplanting human liver cells into humanized mice.

YouTube Preview Image This video is from the youtube username Lemelson MIT

Already using this technique, for many cancer patients, scientists have been able to identify the correct treatment before therapeutically testing the drug on the patient. For instance, scientists at UC Davis of California have been able to develop a new drug delivery system for bladder cancer using humanized mice. In their experiment, mice were specially injected with bladder cancer cells from the patients with the disease and the new treatment method was tried out a dozen times on a number of these mice throughout the project. This way, the most reliable treatment was identified and used on human subjects.

Making Mice More Human, Credit: E. Feliciano, from sceinecenews.org

But this is not the end! Humanized mice are not only useful in cancer treatment, but in studying the effect of infectious agents such as HIV and dengue virus,  and complex diseases such as rheumatoid arthritis  and diabetes. For instance, Doctor Greiner, studies the immune system in hyperglycaemic mice in pursue of a better understanding and therefore cure for type one diabetes which is an autoimmune disease.

Although the day your family doctor will be able to grow a colony of  your personal humanized mice is still years away, this is definitely a revolutionary technique to attempt at fighting diseases that we have yet to cure.

-Ashkan Nasr