ACHOO syndrome: not your usual sneeze

Have you ever experienced a desire to sneeze after looking at an abrupt bright light, like the sun? I know I have, along with about a third of the world’s population.

Photo of a man sneezing. Author: James Gathany via Wikimedia Commons

This surreal way of sneezing is called photic sneeze reflex, or, conveniently, ACHOO syndrome. Despite being highly prevalent around the world, we know very little regarding this phenomenon. In fact, a study has found that victims of this reflex, including myself, think this occurs in everyone, whereas “normal” people become bewildered when finding about its existence. This level of unawareness might be due to the little threat that this condition poses to those who have it.

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Due to the common occurrence of this condition within a family, it is generally regarded as an autosomal dominant trait, which simply means that it is likely for an affected parent to have an affected child. This is surprising, since the sneeze that we are all familiar with is acquired from environmental factors like viruses, regardless of how we are genetically shaped.

So how is it then that the sun or any other light sources trigger sneezing? Many theories were considered, with the first one dating back to Aristotle’s time. He speculated that the sun’s heat had a direct effect on the nose, causing it to become irritated and therefore induce sneezing. Clearly, this hypothesis was refuted later on, because the sneeze disappears if you close both eyes.

The most supported reasoning behind this involves the cranial nerves, particularly the optic and the trigeminal nerves. It is our trigeminal nerve that is primarily responsible for sending information that leads to sneezing to the brain. However, due to the complexity and the compactness of our heads, this nerve occasionally picks up signals from other sources, like the optic nerve. Thus, when some of us look at a bright light that stimulates the optic nerve, it is erroneously translated by the brain as the body’s need to sneeze.

Here is a video that gives a very simplified explanation:

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As I mentioned before, this condition is generally harmless to those who have it. However, it can still pose serious risks in certain situations. For example, it is common for drivers to get a sudden outburst of sunlight shone onto their eyes. 66% of the population would squint their eyes and pull down the sun visors. The remaining 33% on the other hand, would experience an uncontrollable movement caused by the photic sneeze reflex. Considering that they are driving, you can imagine how dangerous that can be.

Although you may find it hard to believe, there is a perk to inheriting this condition. I am sure that all of us had a moment where we had a desire to sneeze, but was not able to produce it. However, this is not a problem for around 2.3 billion people, including myself, since we can deliberately produce a sneeze. Besides, who wouldn’t want to feel elevated, given that a sneeze is 1/8 of an orgasm?

-Sanggi(Daniel) Hong

The Perfect Nap

Have you ever wondered how long the perfect nap is?  As we are all university students I am sure that at one point or another we have had the urge to take that quick nap in an attempt to replenish our mind and body.  However, I feel that most of us have also experienced waking up from our nap feeling groggy and just plain out-of-it.  So what is the secret to a perfect nap?  It is called the power nap!

Nap time by buhny via Flicker Creative Commons

To understand the power nap we must first understand how the stages of our sleep cycle work.  Essentially, sleep comes in various stages.  In the beginning, known as the light sleep stages, you drift off as your brain slows down.  On the other hand, in later states, known as the deep sleep stages, you reach deep sleep and REM.  When we awake from the earlier stages we feel refreshed, alert and energized! This is because your brain hasn’t fully entered the sleep cycle and so waking up from it isn’t a strain on your brain. But on the other hand, if we awake during the deep sleep cycle we wake up feeling groggy and exhausted.  This is because your brain has now entered deep into the sleep cycle, thus interrupting this cycle makes you feel the opposite of refreshed.

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Youtube by AsapSCIENCE

Now you may be wondering how long of a nap this would require to avoid the deep sleep cycle.  Many studies have shown that power naps less than 30 minutes are ideal for most people in achieving optimal results when waking, as these awake you during the light sleep cycle.  For example, there was a study at the University of Düsseldorf that discovered that even naps as short as 6 to 10 minutes were able to restore memory , alertness and better learning/performance.  Additionally, the Flinders University explained through their study that a 10 minute nap was the best length for a nap in terms of recuperation.  This 10 minute length was based on the subjects only having 5 hours of sleep the night prior.

Idea Man by hank_rhoads via Flickr Creative Commons

Idea Man by hank_rhoads via Flickr Creative Commons

Overall, the power nap can be extremely efficient in dealing with exhaustion and a fatigued mind when done right.  It seems weird that a shorter amount of napping time will lead to better results when waking up, but we must consider how our brain functions when we sleep.  So the next time you get back from lecture and only have an hour or so before your next lecture, why not try out a quick power nap to refresh and replenish your mind and body!

-Derek Rejto

Hairy Eyeball?!

I think we can all agree that one of the most annoying occurrences that can happen in our day to day lives is when we get a hair in our eyes.  That annoying feeling, the constant blinking and the frantic rubbing to try and retrieve what feels to be the thickest hair you’ve ever made out of one of the most sensitive parts of our body.  Now, imagine how this unnamed 19-year old man from Iran felt when doctors found out he had hairs growing out of his eyeballs.

A Limbal Dermoid. Author: A Akram, via Flickr Creative Commons

Now, this isn’t something sudden that just appeared in this young mans eye, but is actually something that had been with him since he was born and gradually increased in size as he got older.  While not causing any physical pain, it had caused the young man to have vision defects as the effected eye saw 20/60  while the left eye saw 20/20.  It also caused him mild discomfort when blinking and what is reported as, “an intermittent sensation of the presence of a foreign body.”  From the above symptoms and conducting their own tests, doctors were able to identify the mass as a limbal dermoid, a very rare tumour mass found in about one in 10,000 patients made of special choristomatous tissue .

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Video from Youtube by user: 1OneMinuteNews.

Choristomatous tissue is made from the tissue of other body parts.  For example: the tissue in fat, sweat glands, muscles, teeth, cartilage, bone, and skin can all make up choristomatous tissue.  This explains how the young man has hairs growing out of his limbal dermoid, as the tissues in his tumour could be made of skin cells and also other cellular elements that skin cells are made along with such as hair follicles and sweat glands.

This mass can usually be found in 3 different places of the eye, all around the cornea.  It is either found just outside the cornea, slightly overlapping the cornea or in extreme cases , replacing the cornea itself!   The dermoid can vary in colour depending on the specific tissue found in the tumor mass but it is always firm and “fleshy” in nature and would help explain the discomfort the young man felt every time he closed his eye as well as the sensation of the presence of a foreign body.

Luckily, the 19 year-old man  didn’t have the horrific case of having his entire cornea replaced as the tumour was found bordering his cornea (see picture above).  This story also ends with a happily as doctors were able to successfully remove the 5mm by 6mm mass.  While doctors don’t expect improvement in his vision due to this removal, I know for sure he’ll be very happy not having hairs in his eye all the time.

– Ho-Hin Leung

Living with Only Half a Brain?

It is actually possible! There are many cases around the world where people are living with only half a brain. This ability for people to live with only half a brain is due to a brain phenomenon known as plasticity.  Plasticity is the capability of the brain to be modeled by experience. Experiences that we gain throughout our lifetime changes our brain, like modelling clay.

Brain development begins before birth and continues rapidly after. Connections in the brain are created through synapses which allow electrical signals to be transmitted from one area of the brain to another. These synapses are the changes that are responsible for the brain’s plasticity.

Brain development happens through synapses, which are responsible for creating connections. Image obtained via wikimedia commons author US Government.

There are two types of processes that model the brain: experience-expectant plasticity and experience-dependent plasticity.

Experience-expectant plasticity are experiences that every healthy individual expects to gain in their lifetime. For example, vision. With this type of plasticity comes a sensitive time period. If this experience is not met within this limited time period, the window closes and the skill can no longer be developed.

The other type of plasticity is called experience-dependent plasticity. These are neural connections that are created through experience, which can occur throughout the lifetime. These experiences include riding a bike and learning a musical instrument.

The brain’s plasticity can be seen in Michelle Mack, who was born with only the right side of her brain. To compensate for the missing side, the right side of her brain was rewired to take over the functions of the left.

Human brain’s division into the right and left hemispheres. Image obtained via wikimedia commons author Gvdmoort.

Due to the sensitive time period, a child’s brain has a better chance than an adult’s brain to reorganize itself and recover from a brain injury or surgery. 

This sensitive period plasticity is demonstrated in a girl in North Carolina named Cameron Mott. At age 3, she was experiencing 10-15 seizures a day due to an inflammation of the right side of her brain. She underwent surgery to remove the inflamed side of her brain which paralyzed the left side of her body. Immediately after the surgery, she was put into intensive therapy to recover the left side. Due to the brain’s plasticity and her young age, the left side of her brain was able to take over the functions of the right side.

A segment called Today’s Health on the Today Show interviewed Cameron Mott and her family about Cameron’s extraordinary condition:

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The Today Show’s segment, YouTube video from username ichoosepeople.  

Scientists used to believe that the brain was hard-wired and could not undergo changes once the brain was developed. There was the belief that children with only one side of their brain would not be able to live but these real cases have shown the brain’s capability to change known as plasticity.

– Christine Wong

Sci-Fi turned into reality: Transplant organ made from plastic!

A lot of things around us are made of plastic, but did you know that plastic commonly found in soda bottles can be made into a fully functional organ that can be transplanted into patients?

Human organ is one of the most scarce medical resources.  For example, in Canada last year, nearly 5000 Canadians were on waiting list for organ transplant, and about 200 people died while waiting for one. What if YOU needed a transplant organ one day? Wouldn’t it be nice if there were a way to synthesize human organs from scratch? It turns out that stem cell research is the most promising solution to organ shortage.

So what are stem cells? Stem cells are cells that have the ability to self-renew and turn into specialized cells. Examples of stem cells include bone marrow cells and blood cells.

A couple of years ago, a patient named Andemariam Beyene had a tumor in his windpipe and was out of treatment options. His doctor Paolo Macchiarini came up with a radical idea: to build a new windpipe out of plastic and the patient’s own stem cells.

Video about Mr. Beyene’s plastic trachea: 

http://youtu.be/_GyQWAiDu0w

(From youtube user NTDTV)

The tissue engineers first obtained CT scans of the patient’s existing trachea and tailor-made the plastic trachea to ensure it matched precisely.  They then covered the plastic with the patient’s bone marrow stem cells and placed it in a in an incubator.

After two days, the semi-artificial organ was implanted into the patient’s body. The surgery was a success and Mr. Beyene is now breathing normally. In fact, he does not even need to take drugs to prevent organ rejection issues (which are common problems associated with donor organs) because his own cells were used to develop the transplant organ.  

As of today, only simple organs like windpipe have been made from stem cell and transplanted, but the future of stem cell research is promising. It’s possible that in 10 years or so, complex organs built from stem cell will save your life!

-Stella Meng

Do you want happy and healthy life? Eat veggies!

For a long time, we all have been heard how vegetables are good for health. It is highly recommend to have fruits and vegetables regularly.YouTube Preview Image

But how specifically do they make us healthier?

A new study  reveals that vegetables improve not only physical health but also psychological health by increasing optimistic level, and as we know, psychological well being is closely associated with physical well being.

Veggies by Danny. O via Flicker Creative Commons

According to a recent research done by Dr. Boehem at Harvard School of Public Health, people having three or more servings of  fruits and vegetables a day showed significantly higher level of carotenoid in blood than people having less than two servings of fruits and vegetables. Carotenoid , which is rich in vegetables, is a type of antioxidant which is well known for preventing some forms of heart disease and cancer. 

Interestingly, this higher level of carotenoid is also associated with  more optimistic thinking. Optimism ultimately leads to longer and healthier lives as it lowers cancer heart disease, and other chronic disease rates. 

The fact that more optimistic people showed tendency of engaing in healthier behavior such as eating fruits and vegetables and avoiding cigarette smoking, Dr. Boehem’s study only partially explains the relationship between optimism and level of carotenoid.

However, Dr. Boehem indicated that even though optimism level and carotenoid level cannot be conclusively determined, this finding is a promising association.

 

A specific example of showing how veggie may help people to be more optimistic is effect of tomatoes. Researchers analyzed that tomato rich diet lowers the chances of suffering depression.

Tomatoes by Sean Duan via Flicker Creative Commons

Researchers analyzed that tomato rich diet lowers the chances of suffering depression. This research showed high level of antioxidant chemicals in tomatoes reduces oxidative stress and damage to healthy brain cells, and consequently promotes both psychological and physiological health. According to research published in the Journal of Affective Disorders  , people eating tomatoes two to six times a week had 46% lower chance of suffering depression than people who eating less than once a week.

Both mental and physical health are critical for our lives.                                               A long stressful and depressed life or happy but short life is not what we want to live.

Healthy and optimistic life can be easily achieved. Eat veggies!!

 

Why I Wouldn’t Follow Dr. Oz Down the Yellow Brick Road

Dr. Mehmet Oz was educated at Ivy League universities, has won numerous medical awards, is a professor and vice-chair of surgery at Columbia University College of Physicians and Surgeons and came to prominence giving medical advice on the television show Oprah. Sounds highly credible right? On paper yes, but let’s take a closer look.

Photo of Dr.Oz at the Time 100 Gala. Author: David Shankbone, via Wikimedia Commons

First, let’s talk about those “miracle supplements” Dr. Oz so commonly refers to; in particular, Garcinia cambogiaDr. Oz stated that this was “the newest, fastest fat-buster.

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From YouTube user: garciniacambogia009

No exercise, no diet, no effort? It sounds too good to be true, right?  It is.

Slate.com was first to bust this “find” and stated that in 1998 a study looked at its effects as an “antiobesity agent” in 135 people and found that Garcinia cambogia pills were no better than placebo for weight loss. More recently, a study involving 706 participants was unable to provide support that Garcinia cambogia extract had any impact on weight. In some studies, a few trials showed short-term slimming, but the overall effects were so small and most studies were so flawed that the authors were unable to conclude any results. Dr. Oz handpicked data to support his claims because really, who wants to watch a television show exclaiming “Garcinia cambogia: Proven to do nothing!” It seems Dr. Oz has sold his scientific morals for ratings.

Experiencing large disapproval from the scientific community, Dr. Oz decided to conduct his very own experiment to prove he still has his roots firmly planted in the scientific method. Unfortunately, Dr. Oz only managed to add supporting evidence that he does not follow good scientific practices. Looking for toxic levels of arsenic, he tested apple juice from five popular juice makers in the U.S. claiming that he found toxic levels in all five. There are too many problems with this study. First, Dr. Oz asked a lab to test for total arsenic, but there are two forms of arsenic: Organic and inorganic. Organic is found everywhere and is practically harmless. He received a warning letter from the FDA stating that arsenic occurs naturally in many foods and that only inorganic forms are toxic. Testing for total arsenic can therefore not be used to determine whether a food is unsafe. Second, never replicated his own results. He didn’t even question the numbers he got from the lab, which the FDA warned were giving erroneously high results. Yet, Dr. Oz  showed no hesitance when reporting the results on his show. He didn’t express even the slightest uncertainty about his findings. Even the media caught on. ABC’s medical editor interviewed Dr. Oz who danced around the accusations.

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From YouTube user: ABCNews 

These are just a couple instances of Dr. Oz demonstrating a lack of adherence to scientific principles. He may have the brains and the heart for science, but Dr. Oz needs to find his courage as he presents himself as the cowardly lion far too often.

-Nicole Gehring

Ahchoo: Oh no not the flu!

Flu season is gearing up here in Canada so I figured it to be a good time to talk about the flu. Three years ago, there was an unusual flu outbreak with a nasty variant that seemed like it could turn into a pandemic. This year is also a non-typical flu season, as most seasons are. The rate of influenza infection has been on the rise early this year. This means either one of two things: it could mean we are having a flu season that will normalize once it is all over but shifted early or it could mean that we are having a very bad flu season, during which we will see a high peak rate of infection and what we are seeing now is just the beginning.

Flu Trends in BC. Canada: Influenza-like illness (ILI) data provided publicly by the Public Health Agency of Canada.

Doctors recommend that everyone that is 6 months of age or older get the flu shot. If you already got a flu shot this year,  your immune system has been signaled to prepare itself for the invasion of three different strains of flu. A mild reaction such as soreness, headaches and fevers are common side effects of the flu vaccine. There is no downside to getting the flu vaccine other than a few mild side effects, in fact, if more people got the flu vaccine there would be less people getting sick and dying from the influenza virus.

So the question is, “Do I really need to get the flu shot every year?” and to be honest it really depends who you are and who you are around. If you’ve just had a baby, hang out with your grandparents a lot or hang out with someone who is immune-comprised, you’d better get the shot otherwise you risk giving the virus to those who already have a weaker immune system. If you’re a student then getting the vaccine might not be so dramatic although dorms, gyms and schools are warm and moist and what virus isn’t going to love that combination, its basically a giant petri dish. If one person gets sick, everyone gets sick. So it really comes down to can you afford to be sick.

There is no benefit to getting sick with the influenza virus. In fact, there is no reason to even get the influenza virus. We have a vaccine. Yes, there is always the risk that the vaccine may not contain the correct strains and you might get sick anyways but might as well stack the deck in your favor to keep yourself from getting sick.

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G-Flux: Formula for a Superior Body Composition

The popularity of fitness training seems to have increased exponentially over the past couple of years or so. Fortunately, this means that people generally are more educated about how to train and eat properly. However, although people are finally realizing that the “less is best” diet is the most effective, many individuals who are mindful of caloric intake and expenditure do not know that there is an association between the level of this energy balance and body composition. Enter John Berardi‘s principle of G-flux.

Balance of energy in the body (Found at: http://www.180degreefitnesssystems.com/images/negative_energy_balance.jpg)

John Berardi argues that a higher energy balance, that is, a higher amount of energy into the body accompanied by higher energy expenditure by the body, is superior for body composition. So how does G-flux work? Take, for example, an individual who does little to no physical activity from week to week. This person’s daily requirement of calories to maintain their current body composition will be low, due to low energy expenditure. If the same individual were to engage in five to seven hours of weekly physical activity, their energy expenditure will be much higher. Provided that the energy taken into the body (food eaten) balances the caloric expenditure, energy balance level or G-flux, will be higher. G-flux says that the net effect of this higher energy balance is a body that not only possesses a superior composition, but performs better, also.

Ultimate couch potatoes. Author: LAIntern, via Wikimedia Commons

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Usain Bolt after World Record breaking 100m at Beijing Olympics. Author: Richard Giles, via Wikimedia Commons

Some might ask how the body can produce a better composition while still taking in maintenance levels of calories. Many experienced athletes, fitness buffs and studies will tell you that in order to cut fat, a caloric deficit must be achieved – the amount of calories taken into the body (through food) is less than the calories burned through exercise and other activities. This is a tried and true method for leaning out the body, but in a state of caloric deficit the body builds little to no muscle, and other effects such as fatigue may occur. In a state of high G-flux, however, the body is in an environment where fat loss is promoted through intense and frequent activity while still being able to build muscle at maintenance calories.

A great (and humorous) explanation of G-flux by YouTuber, Omar Isuf.

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How can you increase your G-flux? Simply increase your weekly exercise. Choose physical activities that are relevant to your fitness goals and do them for a minimum of five to seven hours a week, while increasing your food intake accordingly to achieve that higher energy balance.

– Curtis M.

For more information on diet and caloric intake, see Earvin Remandaban’s post.

Action Games: Tools for Improving the Mind?

Student playing Counterstrike Source
By ario_ via Flickr Creative Commons

Often, when we are asked to describe a “video gamer”, we think of a person lazing around in front of their computer or tv, wasting time playing games as their brain turns to mush. Personally, I enjoy playing video games once in a while, but they were of no value to me other than for entertainment. That was until I took a psychology course at UBC and discovered that people who played action video games often had better spatial attention than the average non-gamer.

What is Spatial Attention?
Imagine that you’re at a restaurant with some friends; people nearby are chatting loudly, waiters and waitresses are hurrying back and forth with plates, cell phones are ringing, background music is playing and yet, you are able to ignore these distractions and focus on the conversation you are having with your friends. This is your spatial attention at work. You are shutting out the unnecessary sensory inputs and only engaging in the information relevant to your conversation.

Gamers vs. Non-Gamers

A study conducted at the University of Rochester by D. Bavelier and associates, found that VGPs (video game players) displayed greater suppression of irrelevant information than NVGPs (non video gamer players). Subjects were asked to press a button to indicate whether a specific shape was present or not in the  given visual stimuli (figure 1), which included various shapes and moving distractors. As a result, the researchers concluded that VGPs expressed shorter reaction times, suggesting that they are more effective in filtering out irrelevant information. Furthermore, fMRI brain imaging showed that areas involved in spatial attention were less engaged in VGPs than in NVGPs. In other words, non video game players required more effort to ignore distractions, unlike video game players who seemed to do it almost automatically. 

In an attempt to identify differences in cognitive performance between VGPs and NVGPs, researchers assessed numerous individuals in their attention, memory and executive control skills. Overall, it was found that experienced gamers could track faster moving objects, posessed better visual short term memory, were quicker at switching between tasks and were more effective in mentally rotating objects than non-gamers. Interestingly enough, the researchers also suggest that non-gamers could potentially improve their cognitive skills with increased video game experience.

Have 18 minutes to spare? (probably not..) But for those who are really interested, here is a video of cognitive researcher Daphne Bavelier giving a talk about the effect of video games on our brains. She addresses topics such as eyesight, attention, multi-tasking and much more. I found this quite interesting.

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Although  video game players overall display better cognitive performance than non-video game players, it does not mean you should spend most of your time now playing video games in place of studying or other important tasks. However, the next time you decide to take a study break, consider playing an action game. With the right dose, you can de-stress and potentially improve your spatial attention at the same time!

– Grace Lam